For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. bovis AF2122 / 97 Mb3484c (truA)

annotation: tRNA pseudouridine synthase A
coordinates: 3823752 - 3824645
length: 297

VSLTRRPPKSPPQRPPRISGVVRLRLDIAYDGTDFAGWAAQVGQRTVAGDLDAALTTIFRTPVRLRAAGR
TDAGVHASGQVAHVDVPADALPNAYPRAGHVGDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSAL
RRHYVYRLSTAPYGVEPQQARYITAWPRELDLDAMTAASRDLMGLHDFAAFCRHREGATTIRDLQRLDWS
RAGTLVTAHVTADAFCWSMVRSLVGALLAVGEHRRATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPP
DDQLASRNLVTRDVRSG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3484ctruA-100% (297)tRNA pseudouridine synthase A

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4968truA1e-12171.33% (293) tRNA pseudouridine synthase A
M. tuberculosis H37RvRv3455ctruA1e-173100.00% (297) tRNA pseudouridine synthase A
M. leprae Br4923MLBr_01955truA1e-11377.24% (246) putative pseudouridylate synthase
M. abscessus ATCC 19977MAB_3768c-1e-10569.20% (276) tRNA pseudouridine synthase A
M. marinum MMMAR_1092truA1e-11483.76% (234) pseudouridine synthase a, TruA
M. avium 104MAV_4395truA1e-12283.20% (250) tRNA pseudouridine synthase A
M. smegmatis MC2 155MSMEG_1527truA1e-11672.92% (277) tRNA pseudouridine synthase A
M. thermoresistible (build 8)TH_0034truA1e-12076.09% (276) PROBABLE TRNA PSEUDOURIDINE SYNTHASE A TRUA (PSEUDOURIDYLATE
M. ulcerans Agy99MUL_0850truA1e-12482.81% (256) tRNA pseudouridine synthase A
M. vanbaalenii PYR-1Mvan_1438truA1e-12176.00% (275) tRNA pseudouridine synthase A

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4968|M.gilvum_PYR-GCK          MKPSSQPVNEPATDSGGGFV--------RLRLDIAYDGTDFAGWATQAGQ
Mvan_1438|M.vanbaalenii_PYR-1       -------MNEPATDSGGGLVFISSRPGVRLRLDIAYDGTDFAGWATQAGQ
MSMEG_1527|M.smegmatis_MC2_155      ---------MPAIESGGGHV--------RLRLDIAYDGTDFAGWAVQAGQ
TH_0034|M.thermoresistible__bu      ---------MPAIDSGGGHV--------RLRLDIAYDGTDFAGWATQAGQ
Mb3484c|M.bovis_AF2122/97           ------MSLTRRPPKSPPQRPPRISGVVRLRLDIAYDGTDFAGWAAQVGQ
Rv3455c|M.tuberculosis_H37Rv        ------MSLTRRPPKSPPQRPPRISGVVRLRLDIAYDGTDFAGWAAQVGQ
MMAR_1092|M.marinum_M               --------------------------------------------------
MUL_0850|M.ulcerans_Agy99           ---------------------------------------------MQTGQ
MLBr_01955|M.leprae_Br4923          --------------------------------------------------
MAV_4395|M.avium_104                --------------------------------------------------
MAB_3768c|M.abscessus_ATCC_199      ---MVTSHDQPAIPDGGLVR---------LRLDIAYDGTDFAGWATQVNQ
                                                                                      

Mflv_4968|M.gilvum_PYR-GCK          RTVAGVIDDALSTVFRTPVLTRAAGRTDSGVHATGQVAHADIPTDALPHA
Mvan_1438|M.vanbaalenii_PYR-1       RTVAGAIDDALSTVFRTPVVTRAAGRTDSGVHATGQVAHVDVPADALPYA
MSMEG_1527|M.smegmatis_MC2_155      RTVAGVIDEALTTVFRTPVVTRVAGRTDTGVHATGQVAHVDVPAEALPHA
TH_0034|M.thermoresistible__bu      RTVAGVLEEALSTVFRTALQLRGAGRTDTGVHATGQVAHVDVPADALVHA
Mb3484c|M.bovis_AF2122/97           RTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNA
Rv3455c|M.tuberculosis_H37Rv        RTVAGDLDAALTTIFRTPVRLRAAGRTDAGVHASGQVAHVDVPADALPNA
MMAR_1092|M.marinum_M               ------------------MRLRAAGRTDAGVHATGQVAHADVPVDALPNA
MUL_0850|M.ulcerans_Agy99           RTVAGVLDEALTTVLRTPVRLRAAGRTDAGVHATGQVAHADVPVDALPNA
MLBr_01955|M.leprae_Br4923          -----MLDEAFTTVFRTPVRLRAAGRTDTGVHATGQVAHVDIPGTALSKA
MAV_4395|M.avium_104                --MAGVLDEALTTVFRTPVRLRAAGRTDAGVHATGQVAHLDVPGTALPNA
MAB_3768c|M.abscessus_ATCC_199      RTVAGVLGEAFTTIVGDSVQLYAAGRTDAGVHATGQVAHLDVPVACLPGL
                                                      :    *****:****:***** *:*  .*   

Mflv_4968|M.gilvum_PYR-GCK          YPRTVRAGEPEFGPLVRRLGRMLTEDVRVRGIVRAAPGFDARFSALRRHY
Mvan_1438|M.vanbaalenii_PYR-1       YPRTTRPGEAEFGPLVRRLGRMLPEDVRVREITRAAPGFDARFSALRRHY
MSMEG_1527|M.smegmatis_MC2_155      YPRHTRPTDAEFTPLVRRLAGFLPADVRVRDIVRAPAGFDARFSALRRHY
TH_0034|M.thermoresistible__bu      YPRTGRPAGHEFLPLVRRLARFLPTDVRVLDIRRAAPGFDARFSALRRHY
Mb3484c|M.bovis_AF2122/97           YPRAGHVGDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHY
Rv3455c|M.tuberculosis_H37Rv        YPRAGHVGDPEFLPLLRRLGRFLPADVRILDITRAPAGFDARFSALRRHY
MMAR_1092|M.marinum_M               YSRSARAGDPEFLPLVRRLARFLPADLRVLDIARAPTAFDARFSALRRHY
MUL_0850|M.ulcerans_Agy99           YSRSARAGDPEFLPLVRRLARFLPADLRVLDIARAPTAFDARFSALRRHY
MLBr_01955|M.leprae_Br4923          NPRSPHTGDPEFLPLLRRLSRLLPVDVRVLDIACAPVGFDARFSALRRHY
MAV_4395|M.avium_104                YPRAPHVGEAEFGPLLRRLGRFLPTDVRVVDITRAPAGFDARFSALRRHY
MAB_3768c|M.abscessus_ATCC_199      RGRYRPAGAPEFDRLVRRLSRFLPSDVRVLDISRAPAHFDARFSALRRHY
                                      *       **  *:***. :*. *:*:  *  *.  ************

Mflv_4968|M.gilvum_PYR-GCK          VYRLTTAPYGVEPAEARFVTAWPRPLDVDAMAGAAQNVLGLHDFAAFCRH
Mvan_1438|M.vanbaalenii_PYR-1       LYRLSTAPYGVEPAEARFVTPWPRPLDVAAMAAAARELVGLHDFAAFCRH
MSMEG_1527|M.smegmatis_MC2_155      VYRLTTAPYGPEPHETRFVTPWTRPLDVDAMNAAAQELLGLNDFAAFCRY
TH_0034|M.thermoresistible__bu      IYRLSVAPYGVMPQLARYVTVWPRPLDVDAMAAASAQLVGLHDFAAFCRH
Mb3484c|M.bovis_AF2122/97           VYRLSTAPYGVEPQQARYITAWPRELDLDAMTAASRDLMGLHDFAAFCRH
Rv3455c|M.tuberculosis_H37Rv        VYRLSTAPYGVEPQQARYITAWPRELDLDAMTAASRDLMGLHDFAAFCRH
MMAR_1092|M.marinum_M               VYRLSTAPYGVEPQQARYVTVWPRELDIDAMTVASRELLGLHNFAAFCRR
MUL_0850|M.ulcerans_Agy99           VYRLSTAPYGVEPQQARYVTVWPRELDIDAMTVASQELLGLHNFAAFCRR
MLBr_01955|M.leprae_Br4923          RYRLSTAPYGVQPNQARYVTAWPRELDLDSMSAASRDLLGLRDFAVFCRH
MAV_4395|M.avium_104                VYRLSTAPWGVLPQQARYVTAWPRPLDVEAMAAASRDLLGLHDFAAFCRH
MAB_3768c|M.abscessus_ATCC_199      EYRLSTASFGVLPLARHDVVGWHRPLDVDAMNEASRNLLGLRDFAAFCRH
                                     ***:.*.:*  *   : :. * * **: :*  *: :::**.:**.*** 

Mflv_4968|M.gilvum_PYR-GCK          RDGATTIRELQRLDCVRDGDRISVHVSADAFCWNMVRSLVGALLAVGEHR
Mvan_1438|M.vanbaalenii_PYR-1       RDGATTIRELQRLDCVRDGDRVEVHVSADAFCWNMVRSLVGALLAVGEHR
MSMEG_1527|M.smegmatis_MC2_155      RAGATTIRDLQRLEWVRNGFYINAYVTADAFCWNMVRSLVGALLKVGEGR
TH_0034|M.thermoresistible__bu      REGATTIRDLQRFDWSRHGDLITANVSADAFCWQMVRSLVGAVLKVGEGR
Mb3484c|M.bovis_AF2122/97           REGATTIRDLQRLDWSRAGTLVTAHVTADAFCWSMVRSLVGALLAVGEHR
Rv3455c|M.tuberculosis_H37Rv        REGATTIRDLQRLDWSRAGTLVTAHVTADAFCWSMVRSLVGALLAVGEHR
MMAR_1092|M.marinum_M               REGATTIRDLQRLDWSRNGHLVTAQVSADAFCWSMVRSLVGALLAVGEHR
MUL_0850|M.ulcerans_Agy99           REGATTIRDLQRLDWSRNGHLVTAQVSADAFCWSMVRSLVGALLAVGEHR
MLBr_01955|M.leprae_Br4923          RHGATTIRELQRLEWSREGYLITAHITADAFCWSMVRSLIGALLAVGDHR
MAV_4395|M.avium_104                RENATTIRDLQRLDWTRDGDLIIARVSADAFCWSMVRSLVGALLAVGENR
MAB_3768c|M.abscessus_ATCC_199      REGATTIRELQRFDWGVDGQRLTAYVSADAFCWSMVRSLVGAVLAVGEGR
                                    * .*****:***::    *  : . ::******.*****:**:* **: *

Mflv_4968|M.gilvum_PYR-GCK          RDDTWCVQLLHARHRSSDFAAAPARGLTLVGVDYPPDDELAARNLVTRDV
Mvan_1438|M.vanbaalenii_PYR-1       RDAAWCAALLDATGRSSDFAAAPARGLTLVGVDYPPDAQLEARNLVTRDL
MSMEG_1527|M.smegmatis_MC2_155      RSPEWTAELLGATSRSSEFPAAPARGLTLAAVDYPPDDELEARNVVTRDV
TH_0034|M.thermoresistible__bu      RDPQWCAALLTATRRSSDFAAAPAQGLTLAGVDYPPDDQLAARIAITRDR
Mb3484c|M.bovis_AF2122/97           RATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDDQLASRNLVTRDV
Rv3455c|M.tuberculosis_H37Rv        RATTWCRELLTATGRSSDFAVAPAHGLTLIQVDYPPDDQLASRNLVTRDV
MMAR_1092|M.marinum_M               RTPDWCRELLTATARSSDFAAAPAHGLVLAKVDYPPDDQLASRVLITRDL
MUL_0850|M.ulcerans_Agy99           RTPDWCRELLTATARSSDFAAAPAHGLVLAKVDYPPDDQLASRVLITRDL
MLBr_01955|M.leprae_Br4923          RTIGWCGELLTKASRSSDFTTAPAHGLTFIRVDYPPDDELAERAVITRDL
MAV_4395|M.avium_104                RPVSWCRELLSATNRSSDYATAPAHGLTLVGVDYPPDDQLAARNLITRDV
MAB_3768c|M.abscessus_ATCC_199      RPVQWCVDLLNKERRSSDFAAAPARGLTLVGVDYPPDDQMAARVMITRDV
                                    *   *   **    ***::..***:**.:  ****** ::  *  :*** 

Mflv_4968|M.gilvum_PYR-GCK          RTADEL--
Mvan_1438|M.vanbaalenii_PYR-1       RTADEL--
MSMEG_1527|M.smegmatis_MC2_155      RTIDQSRD
TH_0034|M.thermoresistible__bu      REL-----
Mb3484c|M.bovis_AF2122/97           RSG-----
Rv3455c|M.tuberculosis_H37Rv        RSG-----
MMAR_1092|M.marinum_M               RSRTD---
MUL_0850|M.ulcerans_Agy99           RSRTD---
MLBr_01955|M.leprae_Br4923          RSSF----
MAV_4395|M.avium_104                RSR-----
MAB_3768c|M.abscessus_ATCC_199      RIRPSG--
                                    *