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VTGQFLWQNVFGVWPVSGEVSAALRGRLHTYAEKAIREAAWHTSWHNPNRAFEDDVHGWLDLVLDGPLAS ELTGLVAHLNSHAESDALAAKLLALTVPGVPDVYQGSELWDDSLVDPDNRRPVDYGTRRVALKALQHPKI RVLAAALRLRRTHPESFLGGAYHPVFAAGPAADHVVAFRRGDDILVAVTRWTVRLQQTGWDHTVLPLPDG SWTDALTGFTASGHTPAVELFADLPVVLLVRDNA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1589c | treYb | - | 100% (244) | maltooligosyltrehalose synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3632 | - | 4e-90 | 62.50% (240) | malto-oligosyltrehalose synthase |
| M. tuberculosis H37Rv | Rv1563c | treY | 1e-144 | 100.00% (244) | maltooligosyltrehalose synthase TreY |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2378 | treY | 1e-106 | 74.17% (240) | maltooligosyltrehalose synthase TreY |
| M. avium 104 | MAV_3211 | treY | 1e-104 | 73.33% (240) | malto-oligosyltrehalose synthase |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_1802 | glgY | 2e-92 | 65.83% (240) | Maltooligosyltrehalose synthase TreY |
| M. ulcerans Agy99 | MUL_1554 | treY | 1e-106 | 74.58% (240) | maltooligosyltrehalose synthase TreY |
| M. vanbaalenii PYR-1 | Mvan_2785 | - | 2e-88 | 62.14% (243) | malto-oligosyltrehalose synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1589c|M.bovis_AF2122/97 --------------------------------------------------
Rv1563c|M.tuberculosis_H37Rv MAFPVISTYRVQMRGRSNGFGFTFADAENLLDYLDDLGVSHLYLSPILTA
MMAR_2378|M.marinum_M MGFPVLSTYRLQLRGPSSGFGFTFADAENVLDYLSELGVSHLYLSPILTA
MUL_1554|M.ulcerans_Agy99 MGFPVLSTYRLQLRGPSSGFGFTFADAENVLDYLSELGVSHLYLSPILTA
MAV_3211|M.avium_104 MGLPVLSSYRLQLRGESSGFAFTFADAEHLLDYLDDLGVTHLYLSPIMTA
Mflv_3632|M.gilvum_PYR-GCK --MTVLSTYRLQMRGPASGEAFTFADAEKLVDYLADLGVSHLYLSPILTA
Mvan_2785|M.vanbaalenii_PYR-1 --MAVLSTYRLQMRGPASGEAFTFADAEKLVDYLADLGVSHLYLSPVLTA
TH_1802|M.thermoresistible__bu --------------------------------------------------
Mb1589c|M.bovis_AF2122/97 --------------------------------------------------
Rv1563c|M.tuberculosis_H37Rv VGGSTHGYDVTDPTTVSPELGGSDGLARLSAAARSRGMGLIVDIVPSHVG
MMAR_2378|M.marinum_M VAGSSHGYDVTDPTTVSAELGGPDGLARLSAAARARGMGLIVDIVPNHVG
MUL_1554|M.ulcerans_Agy99 VAGSSHGYDVTDPTTVSAELGGLDGLARLSAAARARGMGLIVDIVPNHVG
MAV_3211|M.avium_104 TAGSSHGYDVTDPTTVSAELGGRDGLARLSVAARARGMGLVVDIVPNHVG
Mflv_3632|M.gilvum_PYR-GCK GVGSSHGYDVTDPTTISAELGGPEGFARLAATARAAGLGLIVDIVPNHVG
Mvan_2785|M.vanbaalenii_PYR-1 AEGSSHGYDVTDPTTISAELGGPEGFERLVHTARAAGLGVVVDIVPNHVG
TH_1802|M.thermoresistible__bu --------------------------------------------------
Mb1589c|M.bovis_AF2122/97 --------------------------------------------------
Rv1563c|M.tuberculosis_H37Rv VGKPEQNAWWWDVLKFGRSSAYAEFFDIDWELG-DGRIILPLLGSDSDVA
MMAR_2378|M.marinum_M VDRPQQNMWWWDVLRHGRNSEYAGYFDIDWDLDEHGRIVLPVLGSDADVA
MUL_1554|M.ulcerans_Agy99 VDRPQQNMWWWDVLRHGRNSEYAGYFDIDWDLDEHGRIVLPVLGSDADVA
MAV_3211|M.avium_104 IDAPRQNPWWWDVLRNGHSSPYATFFDVDWDLDEDGRIVLPVLGSDDDAA
Mflv_3632|M.gilvum_PYR-GCK VDDPTQNAWWWDLLAHGRSSTYCSYFDVDWTLDPDGRIVLPVLGSDDDVA
Mvan_2785|M.vanbaalenii_PYR-1 VDVPAQNRWWWDLLTHGRGSRYAEFFDIDWTLDPDCRIVLPVLGSDSDVA
TH_1802|M.thermoresistible__bu --------------------------------------------------
Mb1589c|M.bovis_AF2122/97 --------------------------------------------------
Rv1563c|M.tuberculosis_H37Rv NLRVDGDLLRLGDLALPVAPGSGDGTGPAVHDRQHYRLVGWRHGLCGYRR
MMAR_2378|M.marinum_M DLLVDGDLLRLGSLAFPIAAGTGTGTGAEVHERQHYRLVGWRRGLCGYRR
MUL_1554|M.ulcerans_Agy99 DLLVDGDLLRLGSLAFPIAAGTGTGTGAEVHERQHYRLVGWRRGLCGYRR
MAV_3211|M.avium_104 DLTVDGELLRLGDLAFPIAPGTAGGTGPEVHDRQHYRLVGWRNGVCGYRR
Mflv_3632|M.gilvum_PYR-GCK DLEVDGDVLRLGDRTWPIAPGTGDGTGAQVHDRQHYKLIGWRHNVCGYRR
Mvan_2785|M.vanbaalenii_PYR-1 DLAVDGDVLRLGDRTWPITPGTGDGTGPQVHDRQHYKLVGWRNNGCGYRR
TH_1802|M.thermoresistible__bu --------------------------------------------------
Mb1589c|M.bovis_AF2122/97 --------------------------------------------------
Rv1563c|M.tuberculosis_H37Rv FFSITSLAGLRQEDRAVFDASHAEVARWFTEGLVDGVRVDHLDGLSDPSG
MMAR_2378|M.marinum_M FFSITSLAGLRQEDRAVFDASHVEIARWFADGLVDGLRIDHPDGLSDPCG
MUL_1554|M.ulcerans_Agy99 FFSITSLAGLRQEDRAVFDASHVEIARWFADGLVDGLRIDHPDGLSDPCG
MAV_3211|M.avium_104 FFSITSLAGLRQEDPAVFDATHAEVGRWFAEGLVDGVRIDHPDGLSDPCG
Mflv_3632|M.gilvum_PYR-GCK FFSITSLAGIRQEDRAVFDASHAEVKRWFDEGLVDGIRIDHPDGLSDPAG
Mvan_2785|M.vanbaalenii_PYR-1 FFSITSLAGLRQEDRAVFDATHAEVARWFSEGLVDGIRIDHPDGLSDPAG
TH_1802|M.thermoresistible__bu --------------------------------------------------
Mb1589c|M.bovis_AF2122/97 --------------------------------------------------
Rv1563c|M.tuberculosis_H37Rv YLAQLRELLGPNAWIVVEKILAVDEALEPTLPVDGSTGYDVLREIGGVLV
MMAR_2378|M.marinum_M YLQWLRELVGQQAWIVIEKILAADEALEPTLPVDGTTGYDVLRELGGLFA
MUL_1554|M.ulcerans_Agy99 YLQWLRELVGQQAWIVIEKILAADEALEPTLPVDGTTGYDVLRELGGLFA
MAV_3211|M.avium_104 YLARLRELVGPDAWIVIEKILAVDEALEPTLPVAGTTGYDVLREIGGVLL
Mflv_3632|M.gilvum_PYR-GCK YLVWLRELTGPDAWIVIEKILAVDEALDTTLPVAGTTGYDALRENGGLFV
Mvan_2785|M.vanbaalenii_PYR-1 YLAWLRKLTGPQAWIVIEKILAVDEALDSSLPVAGTTGYDALRESGGVFV
TH_1802|M.thermoresistible__bu -----------------------------------------------XFI
Mb1589c|M.bovis_AF2122/97 --------------------------------------------------
Rv1563c|M.tuberculosis_H37Rv DPQGESPLTALVESAGVDYQEMPAMLADLKVHAAVHTLASELRRLRRCIA
MMAR_2378|M.marinum_M DPAGAAELTALVESADVDYQAMAALLADLKIRATTDTLSSELSRLRRSIA
MUL_1554|M.ulcerans_Agy99 DPAGAAALTALVESADVDYQAMAALLADLKIRATTDTLPSELSRLRRSIA
MAV_3211|M.avium_104 DPNGAPALTALVDSSGVDYQAMPKMLAELKIHAATVTLASELGRLRRSIA
Mflv_3632|M.gilvum_PYR-GCK DPTGLRSLTELVEAAGTTPSDAAREARRLKVEAVTTTLSSELARLCRAVI
Mvan_2785|M.vanbaalenii_PYR-1 DPSGAEALTALVESAGIQYSATDGQARALKVTAVTVTLASELARLRRSVV
TH_1802|M.thermoresistible__bu DPAGAGPLTELCESAGFDHRAVHDLARRLKAEAVTDTLGSELARLCRVVA
Mb1589c|M.bovis_AF2122/97 --------------------------------------------------
Rv1563c|M.tuberculosis_H37Rv AAAGADHPLLPAAVAALLRHIGRYRCDYPGQAAVLPCALAETHSTTPQLA
MMAR_2378|M.marinum_M ATAGRDHPLLGEAVAALLTHIGVYRCDYPGLASIMPTAIAETCIAAPELG
MUL_1554|M.ulcerans_Agy99 ATAGRDHPLLGEAVAALLTHIGVYRCDYPGLASIMPTAIAETCIAAPELG
MAV_3211|M.avium_104 AAAGVDHPLLPEAIAALLTNIGVYRCDYPGLVALLPTALAETQSAAPHLG
Mflv_3632|M.gilvum_PYR-GCK AATGSDHELLGSSIAALLSHIGVYRSDYQALSAVLPVAMSDTVAENPDLA
Mvan_2785|M.vanbaalenii_PYR-1 AATGRDHDRLGDAIAALLSRVGVYRSDYLALAGILPVAIAETVSAEPDLA
TH_1802|M.thermoresistible__bu AVTGSDHPQLGAAVAELLGNIGVYRSDYRTLSLVLPAAFGETVSARPDLD
Mb1589c|M.bovis_AF2122/97 --------------------------------------------------
Rv1563c|M.tuberculosis_H37Rv PGLQLIAAAVARGGEPAVRLQQLCGAVSAKAVEDCMFYRDARLVSLNEVG
MMAR_2378|M.marinum_M PPLQLVATALAHGGEPASRLQQLCGAVTAKAVEDCLFYRDARLVSLNEVG
MUL_1554|M.ulcerans_Agy99 PPLQLVAMALAHGGEPANRLQQLCGAVTAKAVEDCLFYRDARLVSLNEVG
MAV_3211|M.avium_104 PALQVLAAALARGGEPATRLQQLCGAVTAKAVEDCLFYRDARLVSLNEVG
Mflv_3632|M.gilvum_PYR-GCK EPLALLATALEVSVEVSVRLQQLCGAATAKSMEDCLFYRDARLVSLNEVG
Mvan_2785|M.vanbaalenii_PYR-1 EPLTVLATALSH-REVEVRLQQLCGAATAKSMEDCLFYRDARLVSLNEVG
TH_1802|M.thermoresistible__bu EPLTLLAAAVARGGEAAVRLQQLCGAATAKSMEDCLFYRDPRLVSLNEVG
Mb1589c|M.bovis_AF2122/97 --------------------------------------------------
Rv1563c|M.tuberculosis_H37Rv GEPRRFGVGAAEFHHRAATRARLWPRSMTTLSTHDTKRGEDVRARIGVLS
MMAR_2378|M.marinum_M GEPHRFGVSAAEFHHSAAARTRMWPQTMTTLTTHDTKRGEDVRARISVLS
MUL_1554|M.ulcerans_Agy99 GEPHRFGVSAAEFHHSAATRTRMWPQTMTTLTTHDTKRGEDVRARISVLS
MAV_3211|M.avium_104 GEPHRFGVGAAEFHHSAATRARLWPHTMTTLTTHDTKRGEDVRARIGVLS
Mflv_3632|M.gilvum_PYR-GCK GEPERFGVSAAEFHQRAAVRAHLWPDAMTTLTTHDTKRGEDVRARIGVLS
Mvan_2785|M.vanbaalenii_PYR-1 GEPVHFGVGMAEFHQRASVRAALWPQAMTTLTTHDTKRGEDVRARIGVLS
TH_1802|M.thermoresistible__bu GEPAHFGVSLAEFHQRAAARARQWPQAMVALSTHDTKRGEDVRARIGVLS
Mb1589c|M.bovis_AF2122/97 ----------------------MTGQFLWQNVFGVWPVSGEVSAALRGRL
Rv1563c|M.tuberculosis_H37Rv QVPWLWAKFIGHAQAIAPAPDAVTGQFLWQNVFGVWPVSGEVSAALRGRL
MMAR_2378|M.marinum_M QVPSLWAEFVARAESQAPSPDRATGQFLWQNIFGVWPVTGEVSEQLRDRL
MUL_1554|M.ulcerans_Agy99 QVPSLWAEFVARAENQAPSPDRATGQFLWQNIFGVWPVTGEVSEQLRDRL
MAV_3211|M.avium_104 QVPSLWTEFVARWEVAAPSPDPATGQFLWQNIFGVWPVTGEVTAALRERL
Mflv_3632|M.gilvum_PYR-GCK QVPSLWAEMVQGWESGTPSPDRSTGLFLWQNIFGVWPADGAVTDEHRQRL
Mvan_2785|M.vanbaalenii_PYR-1 QVPSLWAELVRGWQLTTPPPDVTTGLFLWQNMFGVWPTDGVVTDELRRRL
TH_1802|M.thermoresistible__bu QVPSLWAAYVQGWEQRCPAPDPSTGLFLWQNIFGVWPVDGDVTDELRSRL
** *****:*****. * *: * **
Mb1589c|M.bovis_AF2122/97 HTYAEKAIREAAWHTSWHNPNRAFEDDVHGWLDLVLDGPLASELTGLVAH
Rv1563c|M.tuberculosis_H37Rv HTYAEKAIREAAWHTSWHNPNRAFEDDVHGWLDLVLDGPLASELTGLVAH
MMAR_2378|M.marinum_M HSYAEKAIREAAWHTSWNDPDSTFEDAVHRWLDAVLDGPVAGQLTQLVDR
MUL_1554|M.ulcerans_Agy99 HSYAEKAIREAAWHTSWNDPDSTFEDAVHRWLDAVLDGPVAGQLTQLVNR
MAV_3211|M.avium_104 HGYAEKAIREAAWHTSWNDPDAAFEEAVHRWLDTVLDGPVAGQLTELVAQ
Mflv_3632|M.gilvum_PYR-GCK HGYAEKAIREAALHTTWNDPDESFEGAVHTWLDSIIDGPVGIELSALVAR
Mvan_2785|M.vanbaalenii_PYR-1 HGYAEKAIREAALRTSWNDPDADFEGAVHSWIDAILDGPVGTEMGALVAR
TH_1802|M.thermoresistible__bu HAYAEKAIREAALHTSWHDPDETFEARVHAWLDAVIDGPVSAELTGLVAR
* ********** :*:*::*: ** ** *:* ::***:. :: ** :
Mb1589c|M.bovis_AF2122/97 LNSHAESDALAAKLLALTVPGVPDVYQGSELWDDSLVDPDNRRPVDYGTR
Rv1563c|M.tuberculosis_H37Rv LNSHAESDALAAKLLALTVPGVPDVYQGSELWDDSLVDPDNRRPVDYGTR
MMAR_2378|M.marinum_M LNPHAASDALGQKLLALTVPGIPDVYQGTELWEDNLVDPDNRRPVDYAAR
MUL_1554|M.ulcerans_Agy99 LNPHAASDALGQKLLALTVPGIPDVYQGTELWEDSLVDPDNRRPVDYAAR
MAV_3211|M.avium_104 LNPHASSDALAQKLLALTVPGIPDVYQGTELWDDSLVDPDNRRPVDYRAR
Mflv_3632|M.gilvum_PYR-GCK LDPHGRSDALGQKLIALTAPGIPDIYQGTELWEDSLVDPDNRRPVDYGAR
Mvan_2785|M.vanbaalenii_PYR-1 LDAHGRNDALGQKLVALTGPGIPDVYQGTELWEDSLVDPDNRRAVDYAAR
TH_1802|M.thermoresistible__bu LDDHARSDALGQKLLALTVPGVPDVYQGTELWEDSLVDPDNRRPVDYPLR
*: *. .***. **:*** **:**:***:***:*.********.*** *
Mb1589c|M.bovis_AF2122/97 RVALKALQHPKIRVLAAALRLRRTHPESFLGGAYHPVFAAGPAADHVVAF
Rv1563c|M.tuberculosis_H37Rv RVALKALQHPKIRVLAAALRLRRTHPESFLGGAYHPVFAAGPAADHVVAF
MMAR_2378|M.marinum_M RAALRELRHPKIRVVSTALRMRRSHPECFLRGAYTPVLASGTAEDHIVAF
MUL_1554|M.ulcerans_Agy99 RAALRELRHPKIRVVSTALRMRRSHPECFLRGAYIPVLASGTAEDHIVAF
MAV_3211|M.avium_104 RAALQALEHPKIRVVTTALRVRRAHPDTFLHGDYAPLLADGDACDHVLAF
Mflv_3632|M.gilvum_PYR-GCK RKALQSLDHPKMRVVRAALQARAERPDTFLSGGHRPLSASGEHATHLVAY
Mvan_2785|M.vanbaalenii_PYR-1 RQALAGAEHPKMRVVRAALHLRRERPETFLSGGYRPLLATGEAAEHLVSF
TH_1802|M.thermoresistible__bu RRKLRTSDHPKLRVVRAALRLRRDRPDVFVSGDYRPLPARGAAREHLIAF
* * ***:**: :**: * :*: *: * : *: * * *::::
Mb1589c|M.bovis_AF2122/97 RRGDDILVAVTRWTVRLQQTGWDHTVLPLPDGSWTDALTGFTASGHTPAV
Rv1563c|M.tuberculosis_H37Rv RRGDDILVAVTRWTVRLQQTGWDHTVLPLPDGSWTDALTGFTASGHTPAV
MMAR_2378|M.marinum_M RRGEDILVAVTRWTVGLQENGWDDTVLPLPEGSWTDTLTGALASGPAPAA
MUL_1554|M.ulcerans_Agy99 RRGEDILVAVTRWTVGLQENGWDDTVLPLPEGSWTDTLTGALASGPAPAA
MAV_3211|M.avium_104 TRGADIVVAVTRWTVRLAEKGWGNTVLPLPDGTWKDALTGSVVDGPTSAA
Mflv_3632|M.gilvum_PYR-GCK LRGEDVLVAASRWTVRLAETGWGATTLTLPDGTWTDRLTGVTHTGAVPAA
Mvan_2785|M.vanbaalenii_PYR-1 GRGDDVVVAASRWTVRLAETGWGETTLVLPDGTWTDRLTGAAYSGAVRAA
TH_1802|M.thermoresistible__bu GRGGDVLVAATRWSVRLAETDWGDTILDLPNGQWTDRIGGGRFSGPVPAA
** *::**.:**:* * :..*. * * **:* *.* : * * . *.
Mb1589c|M.bovis_AF2122/97 ELFADLPVVLLVRDNA
Rv1563c|M.tuberculosis_H37Rv ELFADLPVVLLVRDNA
MMAR_2378|M.marinum_M ELFSELPVVLLERQA-
MUL_1554|M.ulcerans_Agy99 ELFSELPVVLLERQA-
MAV_3211|M.avium_104 QLFAELPVVLLERHHD
Mflv_3632|M.gilvum_PYR-GCK DLFADLPVALLVRT--
Mvan_2785|M.vanbaalenii_PYR-1 ELFANLPVALLERGDA
TH_1802|M.thermoresistible__bu ELFAGLPVVLLERAGV
:**: ***.** *