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MPRAHDDNWDLASSVGATATMVAAGRALATKDPRGLINDPFAEPLVRAVGLDFFTKLIDGELDIATTGNL SPGRAQAMIDGIAVRTKYFDDYFRTATDGGVRQVVILAAGLDARAYRLPWPAGTVVYEIDQPQVIDFKTT TLAGIGAKPTAIRRTVYIDLRADWPAALQAAGLDSTAPTAWLAEGMLIYLPPDPRTGCSTTAPNSVLRAA RSLPNLSRALWISTQAGYEKWRIRFASTAWTSTWRRWCIPANAATSSTTCAPRAGTLRAQCGPTYSGAMV CPFPPHTTTIRSAKSSSSAVV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0746c | - | - | 100% (301) | hypothetical protein Mb0746c |
| M. bovis AF2122 / 97 | Mb1758c | - | 1e-82 | 76.84% (190) | hypothetical protein Mb1758c |
| M. bovis AF2122 / 97 | Mb3432 | - | 1e-65 | 55.10% (245) | hypothetical protein Mb3432 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5025 | - | 3e-78 | 67.92% (212) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv0725c | - | 1e-177 | 100.00% (301) | hypothetical protein Rv0725c |
| M. leprae Br4923 | MLBr_02640 | - | 2e-51 | 52.45% (204) | hypothetical protein MLBr_02640 |
| M. abscessus ATCC 19977 | MAB_3787 | - | 1e-65 | 64.62% (195) | hypothetical protein MAB_3787 |
| M. marinum M | MMAR_1057 | - | 2e-83 | 74.09% (193) | O-methyltransferase |
| M. avium 104 | MAV_4444 | - | 4e-87 | 78.24% (193) | methyltransferase, putative, family protein |
| M. smegmatis MC2 155 | MSMEG_1479 | - | 2e-72 | 69.43% (193) | methyltransferase, putative, family protein |
| M. thermoresistible (build 8) | TH_2706 | - | 2e-66 | 63.21% (193) | PUTATIVE putative methyltransferase |
| M. ulcerans Agy99 | MUL_0816 | - | 5e-83 | 73.58% (193) | O-methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1344 | - | 9e-77 | 72.02% (193) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5025|M.gilvum_PYR-GCK MARTPDDSWDLASSVGATATMVAAGRAVASADPDPLINDPYAEPLVRAVG
Mvan_1344|M.vanbaalenii_PYR-1 MARTADDSWDPASSVGATATMVAAGRAAASADPDPLINDPYAEPLVRAVG
MMAR_1057|M.marinum_M MARTHDDKWDLASSVGATATMVAAGRAMASRDPRGLIDDPFAEPLVRAVG
MUL_0816|M.ulcerans_Agy99 MARTHDDKWDLASSVGATATIVAAGRAMASRDPRGLIDDPFAEPLVRAVG
MAV_4444|M.avium_104 MTRTHDDEWDLASSVGATATMVAAGRAMATKDPRGLIDDPFAEPLVRAVG
MSMEG_1479|M.smegmatis_MC2_155 MVRSDNDTWDLASSVGATATMVAAGRAVVSQDPGGLINDPFAAPLVRAVG
MAB_3787|M.abscessus_ATCC_1997 MARTDDDSWDLASSVGATATMVAAQRALASHVPNPLINDPYAEPLVRAVG
Mb0746c|M.bovis_AF2122/97 MPRAHDDNWDLASSVGATATMVAAGRALATKDPRGLINDPFAEPLVRAVG
Rv0725c|M.tuberculosis_H37Rv MPRAHDDNWDLASSVGATATMVAAGRALATKDPRGLINDPFAEPLVRAVG
TH_2706|M.thermoresistible__bu MARSESDTWDLTSGVGVTATMVAAARALASREPEPLIDDPFAAPLVRAVG
MLBr_02640|M.leprae_Br4923 -MRTHDDTWDIKTSVGTTAVMVAAARAAETDRPDALIRDPYAKLLVTNTG
*: .* ** :.**.**.:*** ** : * ** **:* ** .*
Mflv_5025|M.gilvum_PYR-GCK L-DFFTRMLDGELDLSVFPDSSPE--RAQAMIDGMAVRTRFFDDCCLAAA
Mvan_1344|M.vanbaalenii_PYR-1 L-SFFTKMLDGELDLSQFADGSPE--RVQAMIDGMAVRTRFFDDCCGTST
MMAR_1057|M.marinum_M V-DFFIKMMDGEFDLSVLQNVSSA--KAQAMVDGMAVRTKYFDDYFGDAI
MUL_0816|M.ulcerans_Agy99 V-DFFIKMMDGEFDLSVLQNVSSA--KAQAMVDGMAVRTKYFDDYFGDAI
MAV_4444|M.avium_104 V-DFFTKMMDGELDLDAIENATPV--RIQSMVDGMAVRTKYFDDYFVDAT
MSMEG_1479|M.smegmatis_MC2_155 I-EALTMLADGKFDIEKVLPESAA--RVRANIDEMAVRTKFFDDYFMDAT
MAB_3787|M.abscessus_ATCC_1997 I-EYFTKLASGAFDPEQMAGLVQLGITADGMANGMASRTWYYDTAFESST
Mb0746c|M.bovis_AF2122/97 L-DFFTKLIDGELDIATTGNLSPG--RAQAMIDGIAVRTKYFDDYFRTAT
Rv0725c|M.tuberculosis_H37Rv L-DFFTKLIDGELDIATTGNLSPG--RAQAMIDGIAVRTKYFDDYFRTAT
TH_2706|M.thermoresistible__bu V-EFFTRLVDGDLELPADTAEERA--AAQVLTEVMAVRTRFFDDFFTDAT
MLBr_02640|M.leprae_Br4923 AGALWEAMLDPSMVAKVEAIDAEAAAMVEHMRSYQAVRTNFFDTYFNNAV
: . : . * ** ::* :
Mflv_5025|M.gilvum_PYR-GCK SAGVRQVVILAAGLDARTYRLPWPDGTVVYELDQPDVIAFKTQTLRNLGA
Mvan_1344|M.vanbaalenii_PYR-1 TAGITQVVILASGLDARAYRLGWPAGTVVYELDQPAVIEFKTRTLAGLGA
MMAR_1057|M.marinum_M KSGIRQAVILASGLDARAYRLPWPADTVVYELDQPQVIEFKTNVLADLGA
MUL_0816|M.ulcerans_Agy99 KSGIRQAVILASGLDARAYRLPWPADTVVYELDQPQVIEFKTNVLADLGA
MAV_4444|M.avium_104 DAGVRQVVILASGLDSRAYRLPWPAGTVVYEIDQPRVIEFKSNTLAEVGA
MSMEG_1479|M.smegmatis_MC2_155 GRGVGQAVILASGLDSRAYRLPWPDGTVVYEIDQPDVIEFKTRTLADLGA
MAB_3787|M.abscessus_ATCC_1997 AAGVRQAVILASGLDTRAYRLTWPAGTTVYELDQPEVITFKTDTLAELGA
Mb0746c|M.bovis_AF2122/97 DGGVRQVVILAAGLDARAYRLPWPAGTVVYEIDQPQVIDFKTTTLAGIGA
Rv0725c|M.tuberculosis_H37Rv DGGVRQVVILAAGLDARAYRLPWPAGTVVYEIDQPQVIDFKTTTLAGIGA
TH_2706|M.thermoresistible__bu RVGARQAVILASGLDARAYRLTWPDGTVVYEIDQPEVIAFKTRTLAELGA
MLBr_02640|M.leprae_Br4923 IDGIRQFVILASGLDSRAYRLDWPTGTTVYEIDQPKVLAYKSTTLAEHGV
* * ****:***:*:*** ** .*.***:*** *: :*: .* *.
Mflv_5025|M.gilvum_PYR-GCK EPAATQRPVPVDLREDWPAALRAAGFDATRPTAWLAEGLLIYLPPEAQDA
Mvan_1344|M.vanbaalenii_PYR-1 HPTATHRPVPIDLREDWPAALHAAGFDASRPTAWLAEGLLIYLPPEAQDQ
MMAR_1057|M.marinum_M EPRATRRAIPIDLRGDWPVALRAAGLDTTAPTAWLAEGLLIYLPPEAQDR
MUL_0816|M.ulcerans_Agy99 EPRATRRAIPIDLRGDWPVALRAAGLDTTAPTAWLAEGLLIYLPPEAQDR
MAV_4444|M.avium_104 EPTATRRTIPIDLRGDWPAALSAAGFDPAAPTAWLAEGLLIYLPPEAQDR
MSMEG_1479|M.smegmatis_MC2_155 EPTCERRTVSIDLRDDWPAALRAAGFDPSAPTAWCAEGLLIYLPPEAQDK
MAB_3787|M.abscessus_ATCC_1997 SPSAERRTVAIDLREDWPAALQAAGFDPEQPTVWSAEGLLIYLPPEAQDR
Mb0746c|M.bovis_AF2122/97 KPTAIRRTVYIDLRADWPAALQAAGLDSTAPTAWLAEGMLIYLPPDPRTG
Rv0725c|M.tuberculosis_H37Rv KPTAIRRTVYIDLRADWPAALQAAGLDSTAPTAWLAEGMLIYLPPDPRTG
TH_2706|M.thermoresistible__bu PPTAPHRPVAVDLRDDWPAALTAAGFDPTVATAWSAEGLLRYLPPDAQDR
MLBr_02640|M.leprae_Br4923 TPTADRREVPIDLRQDWPPALRSAGFDPSARTAWLAEGLLMYLPATAQDG
* . :* : :*** *** ** :**:*. *.* ***:* ***. .:
Mflv_5025|M.gilvum_PYR-GCK LFDTVTALSAPGSTL-ATEYVPGIVDFDGAKARALSEPLREHG---LDID
Mvan_1344|M.vanbaalenii_PYR-1 LFDRITALSAPGSTI-ATEYAPGIIDFDDEKARAMSAPMREMG---LDID
MMAR_1057|M.marinum_M LFDNITALSAPGSTV-ATEFVPGIVDFDVDRARQMSGPFRDHG---LDID
MUL_0816|M.ulcerans_Agy99 LFDNITALSAPGSTV-ATEFVPGIVDFDVDRARQMSGPFRDHG---LDID
MAV_4444|M.avium_104 LFDNITALSAPGSTI-ATEFVPGIVDFDAERVREMSGSFREHG---VDID
MSMEG_1479|M.smegmatis_MC2_155 LFDDIHHLSAPGSTV-ATEFVPALKDFDPEKARQATETLTRMG---VDID
MAB_3787|M.abscessus_ATCC_1997 LFASITELSAPGSRL-VCEQVPGLETADFSKARELTRQFAGET---LDLD
Mb0746c|M.bovis_AF2122/97 -----CSTTAPNSVLRAARSLPNLSRALWISTQAGYEKWRIR-------F
Rv0725c|M.tuberculosis_H37Rv -----CSTTAPNSVLRAARSLPNLSRALWISTQAGYEKWRIR-------F
TH_2706|M.thermoresistible__bu LFDHITDLSAPGSRL-ATEDHPGPGAGLGEKADELGRRWREHG---FEVQ
MLBr_02640|M.leprae_Br4923 LFTEIGGLSAVGSRI-AVETSPLHGDEWREQMQLRFRRVSDALGFEQAVD
:* .* : . . *
Mflv_5025|M.gilvum_PYR-GCK MPSLVYTGA-RTPVMDHLRGAGWQVSGTARAELFARFGRPLPQDADGTDP
Mvan_1344|M.vanbaalenii_PYR-1 MPSLVYAGT-RSHVMDYLAGQGWEVTGVPRRELFTRYGRPLPPEAGDTDP
MMAR_1057|M.marinum_M MSSLVYTGA-RNHVVDYLRAKGWDAEGVTRSELFERNGMAVPAPSDD-DP
MUL_0816|M.ulcerans_Agy99 MSSLVYTGA-RNHVVDYLRAKGWDAEGVTRSKLFERNGMAVPAPSDD-DP
MAV_4444|M.avium_104 MASLVYAGE-RNHVIDYLNGLGWRAEGVTRTELFHRHGIEVPAPEHD-DP
MSMEG_1479|M.smegmatis_MC2_155 MPSLIYHGE-RHSASDYLETKGWQMDSAARATLFTRYGLPAPGHDDD-DP
MAB_3787|M.abscessus_ATCC_1997 LESLVYTQE-RQMAADWLAEHGWTVITEENDELYARLNLDPPNPLLR-SI
Mb0746c|M.bovis_AF2122/97 ASTAWTSTW-RRWCIPANAATSSTTCAPRAGTLRAQCGPTYSGAMVCPFP
Rv0725c|M.tuberculosis_H37Rv ASTAWTSTW-RRWCIPANAATSSTTCAPRAGTLRAQCGPTYSGAMVCPFP
TH_2706|M.thermoresistible__bu LSELFHPGE-RTPVVDYLRGRGWDARARPRAEVFAGYGREFPDSAALAAM
MLBr_02640|M.leprae_Br4923 VQELIYHDENRAVVADWLNRHGWRATAQSAPDEMRRVGRWGDGVPMADDK
* . .
Mflv_5025|M.gilvum_PYR-GCK LGEIVYVSATLAADA---
Mvan_1344|M.vanbaalenii_PYR-1 LGEIVYVSAHRPQ-----
MMAR_1057|M.marinum_M LGEIIFISAALTG-----
MUL_0816|M.ulcerans_Agy99 LGEIIFISAALTG-----
MAV_4444|M.avium_104 LGEIIFISATRTG-----
MSMEG_1479|M.smegmatis_MC2_155 LGEIIYISGTLR------
MAB_3787|M.abscessus_ATCC_1997 FPNIVYVDATLG------
Mb0746c|M.bovis_AF2122/97 PHTTTIRSAKSSSSAVV-
Rv0725c|M.tuberculosis_H37Rv PHTTTIRSAKSSSSAVV-
TH_2706|M.thermoresistible__bu RDSSAVTAVRPVVRAGMR
MLBr_02640|M.leprae_Br4923 DAFAEFVTAHRL------