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M. bovis AF2122 / 97 Mb0602 (yrbE2A)

annotation: integral membrane protein YrbE2a
coordinates: 686372 - 687169
length: 265

MTTHAVIITYLRDQTQPAVDAIGGFYRTCVLTGKALVRRPFHWREAIEQGWFITSVSLLPTLAVSIPLTV
LIIFTLNILLAEFGAADISGAGAALGAVTQLGPLTTVLVIAGAGATAICADLGARTIREEIDAMEVLGID
PIHRLVVPRVVAATIVAALLNGAVITIGLVGGFVFSVFIQHVSAGAYVGTLTLVTGLPEVIISVVKSATF
GLIAGLVGCYRGLTTKGGPKGVGTAVNETLVLCVIALFATNVVLTTIGVRFGTGH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0602yrbE2A-100% (265)integral membrane protein YrbE2a
M. bovis AF2122 / 97Mb0173yrbE1Ae-11476.14% (264) integral membrane protein YRBE1A
M. bovis AF2122 / 97Mb3531cyrbE4A2e-8966.67% (240) integral membrane protein YrbE4a

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0713-1e-11679.17% (264) hypothetical protein Mflv_0713
M. tuberculosis H37RvRv0587yrbE2A1e-146100.00% (265) integral membrane protein YrbE2a
M. leprae Br4923MLBr_02587yrbE1A1e-11073.00% (263) hypothetical protein MLBr_02587
M. abscessus ATCC 19977MAB_4155c-1e-8965.10% (255) hypothetical protein MAB_4155c
M. marinum MMMAR_0410yrbE1A1e-11475.68% (259) integral membrane protein YrbE1A
M. avium 104MAV_4553-1e-13391.89% (259) hypothetical protein MAV_4553
M. smegmatis MC2 155MSMEG_0132-1e-11277.82% (257) hypothetical protein MSMEG_0132
M. thermoresistible (build 8)TH_0155-1e-11779.55% (264) CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE4A
M. ulcerans Agy99MUL_1060yrbE1A1e-11575.68% (259) integral membrane protein YrbE1A
M. vanbaalenii PYR-1Mvan_0132-1e-11878.79% (264) hypothetical protein Mvan_0132

CLUSTAL 2.0.9 multiple sequence alignment


Mb0602|M.bovis_AF2122/97            -MTTHAV--IITYLRDQTQPAVDAIGGFYRTCVLTGKALVRRPFHWREAI
Rv0587|M.tuberculosis_H37Rv         -MTTHAV--IITYLRDQTQPAVDAIGGFYRTCVLTGKALVRRPFHWREAI
MAV_4553|M.avium_104                ------M--IANYLRGQIQPGIDAVGGFFRTCVLTGKALFRRPFQWRETI
Mflv_0713|M.gilvum_PYR-GCK          -MTTTSG--LSGYVREQVKPGLLAVGGFVRMCVLVGKATFRTPFQWREFI
Mvan_0132|M.vanbaalenii_PYR-1       -MTSSSN--LTGYVREQVKPGLEAVGGFVRMCVLVGKATLRPPFQWREFI
TH_0155|M.thermoresistible__bu      -VTTTDG--LVGYVRGQAKPVLESVGGFVRMTVLTGKALFKPPFQWREFI
MSMEG_0132|M.smegmatis_MC2_155      MTASTDG--FVDYLRGQLEKPLATVGGFFKMSVMTGKALFTRPFQWKEFV
MMAR_0410|M.marinum_M               -MTTSSGPHLMGYLRDQLETPLTMVGGFFRMCVLTGKALFRRPFQWRELI
MUL_1060|M.ulcerans_Agy99           -MTTSSGPHLMGYLRDQLETSLTMVGGFFRMCVLTGKALFRRPFQWRELI
MLBr_02587|M.leprae_Br4923          -MTTETRSSLVEYAHTKLQTPLVLVGGFFRMLVLTGKALFRRPFQWREFI
MAB_4155c|M.abscessus_ATCC_199      -------------MKQQLAAPARAVGGFVSMSLATFRNIFRRPFQGQEFL
                                                  : :       :***    : . :  .  **: :* :

Mb0602|M.bovis_AF2122/97            EQGWFITSVSLLPTLAVSIPLTVLIIFTLNILLAEFGAADISGAGAALGA
Rv0587|M.tuberculosis_H37Rv         EQGWFITSVSLLPTLAVSIPLTVLIIFTLNILLAEFGAADISGAGAALGA
MAV_4553|M.avium_104                EQGWFITSVSLLPTLAVAIPLTVLIIFTLNILLAEFGAADISGAGAALGA
Mflv_0713|M.gilvum_PYR-GCK          LQSWFLLRVAFLPTVAVSIPLTVLLIFTLNILLTEFGAADISGAGAALGA
Mvan_0132|M.vanbaalenii_PYR-1       LQSWFLMRVAFLPTLAVSIPLTVLLIFTLNILLAEFGAADVSGAGAAIGA
TH_0155|M.thermoresistible__bu      LQAWFLFRVSFLPTIAVSIPLTVLIIFTLNILLAEFGAADVSGAGAALGA
MSMEG_0132|M.smegmatis_MC2_155      LQSWFLIRVAFLPTLAVSIPLTVLIIFTLNILLAEFGAADVSGAGAALGA
MMAR_0410|M.marinum_M               LQCWFVMRVALLPTIMVSIPLTVLLIFTLNVLLAQFGAADISGAGAAIGA
MUL_1060|M.ulcerans_Agy99           LQCWFVMRVALLPTIMVSIPLTVLLIFTLNVLLAQFGAADISGAGAAIGA
MLBr_02587|M.leprae_Br4923          LQCWFIMRVAFLPTVMVSIPLTVLLIFTLNVLLAQFSAADLSGAGAAIGA
MAB_4155c|M.abscessus_ATCC_199      DQTWFIARVSLLPTLLVAIPFTVLVAFTLNILLREIGAADLSGAATAFGT
                                     * **:  *::***: *:**:***: ****:** ::.***:***.:*:*:

Mb0602|M.bovis_AF2122/97            VTQLGPLTTVLVIAGAGATAICADLGARTIREEIDAMEVLGIDPIHRLVV
Rv0587|M.tuberculosis_H37Rv         VTQLGPLTTVLVIAGAGATAICADLGARTIREEIDAMEVLGIDPIHRLVV
MAV_4553|M.avium_104                VTQLGPLTTVLVIAGAGSTAICADLGARTIREEIDALEVLGIDPIHRLVV
Mflv_0713|M.gilvum_PYR-GCK          VTQLGPLVTVLVVAGAGSTAICADLGARTIREEIDALEVLGIDPIHRLVV
Mvan_0132|M.vanbaalenii_PYR-1       VTQLGPLVTVLVVAGAGSTAICADLGARTIREEIDALEVLGIDPIHRLVV
TH_0155|M.thermoresistible__bu      VTQLGPLVTVLVVAGAGSTAICADLGARTIREEIDALEVLGIDPIHRLVV
MSMEG_0132|M.smegmatis_MC2_155      VTQLGPLVTVLVVAGAGSTAICADLGARTVREEIDALEVLGIDPIERLVV
MMAR_0410|M.marinum_M               VTQLGPLTTVLVVAGAGSTAICADLGARTIREEIDAMEVLGIDPIHRLVV
MUL_1060|M.ulcerans_Agy99           VTQLGPLTTVLVVAGAGSTAICADLGARTIREEIDAMEVLGIDPIHRLVV
MLBr_02587|M.leprae_Br4923          VTQLGPLTTVLVVAGAGSTSICADLGARTIREEIDAMEVLGIDPIHRLVV
MAB_4155c|M.abscessus_ATCC_199      VTQLGPVVTVLVVAGAGATAICADLGARTIREEIDAMQVLGIDPIQRLVV
                                    ******:.****:****:*:*********:******::*******.****

Mb0602|M.bovis_AF2122/97            PRVVAATIVAALLNGAVITIGLVGGFVFSVFIQHVSAGAYVGTLTLVTGL
Rv0587|M.tuberculosis_H37Rv         PRVVAATIVAALLNGAVITIGLVGGFVFSVFIQHVSAGAYVGTLTLVTGL
MAV_4553|M.avium_104                PRVVAATIVATLLNGAVITIGLVGGFVFGVFIQHISAGAYVGTLTLITGL
Mflv_0713|M.gilvum_PYR-GCK          PRVIASTFVAMLLNGAVITIGLVGGFIFGVYLQNVSAGAYVSTLTLVTGL
Mvan_0132|M.vanbaalenii_PYR-1       PRVVASTFVAILLNGAVITVGLVGGFIFGVYLQNVSAGAYVSTLTLITGL
TH_0155|M.thermoresistible__bu      PRVVASTFVALLLNGAVITIGLVGGFVFGVYVQNVSAGAYLSTLTLVTGL
MSMEG_0132|M.smegmatis_MC2_155      PRVVASTFVAFMLNGAVITIGLVGGFFFGVYIQNVSAGAYVSTLTLLTGF
MMAR_0410|M.marinum_M               PRVIAATFVATLLNALVITVGLVGGYLFGVYLQNINGGAYLATLTTITGM
MUL_1060|M.ulcerans_Agy99           PRVIAATFVATLLNALVITVGLVGGYLFGVYLQNINGGAYLATLTTITGM
MLBr_02587|M.leprae_Br4923          PRVLAATLVATLLNGLVITVGLVGGYLFGVYLQNVSGGAYLATLTTITGL
MAB_4155c|M.abscessus_ATCC_199      PRVLASTFVALLLNGLVCAIGMVGGYVFSVFLQGVNPGAFINGLTVLTGL
                                    ***:*:*:** :**. * ::*:***:.*.*::* :. **::  ** :**:

Mb0602|M.bovis_AF2122/97            PEVIISVVKSATFGLIAGLVGCYRGLTTKGGPKGVGTAVNETLVLCVIAL
Rv0587|M.tuberculosis_H37Rv         PEVIISVVKSATFGLIAGLVGCYRGLTTKGGPKGVGTAVNETLVLCVIAL
MAV_4553|M.avium_104                PEVVISVVKSATFGTIAGLVGCYRGLTTKGGPKGVGTAVNETLVLCVIAL
Mflv_0713|M.gilvum_PYR-GCK          PEVLISLVKALTFGLIAGLVGCYRGLTVAGGAKGVGTAVNETLVLCVIAL
Mvan_0132|M.vanbaalenii_PYR-1       PEVVISIVKAATFGLIAGLVGCYRGLTVAGGAKGVGTAVNETLVLCVIAL
TH_0155|M.thermoresistible__bu      PEVVISIVKATTFGLIAGLVGCYRGLTVSGGAKGVGTAVNETLVLCVIAL
MSMEG_0132|M.smegmatis_MC2_155      PEVLISVVKATLFGMIAGLVGCYRGLTVAGGSKGVGTAVNETLVLCVVAL
MMAR_0410|M.marinum_M               PEVTIAMVKAATFGLIAGLVGCYRGLTVRGGSKGLGTAVNETVVLCVVAL
MUL_1060|M.ulcerans_Agy99           PEVTIAMVKAATFGLIAGLVGCYRGLTVRGGSKGLGTAVNETVVLCVVAL
MLBr_02587|M.leprae_Br4923          PEVVIATVKAATFGLIAGLVGCYRGLIVRGGSNGLGAAVNETVVLCVVAL
MAB_4155c|M.abscessus_ATCC_199      GELMISEVKAFLFGIFAGLVGCYRGLTVKGGPKGVGDAVNETVVYAFICL
                                     *: *: **:  ** :********** . **.:*:* *****:* ..:.*

Mb0602|M.bovis_AF2122/97            FATNVVLTTIGVRFGTGH
Rv0587|M.tuberculosis_H37Rv         FATNVVLTTIGVRFGTGH
MAV_4553|M.avium_104                FAVNVVLTTIGVRFGTGR
Mflv_0713|M.gilvum_PYR-GCK          FAVNVVLTTIGVRFGTGT
Mvan_0132|M.vanbaalenii_PYR-1       FAVNVVLTTIGVRFGTGS
TH_0155|M.thermoresistible__bu      FAVNVILTTIGVRFGTGR
MSMEG_0132|M.smegmatis_MC2_155      FAVNVVLTTIGVRFGTGR
MMAR_0410|M.marinum_M               YAVNVILTTIGVRFGTGH
MUL_1060|M.ulcerans_Agy99           YAVNVILTTIGVRFGTGH
MLBr_02587|M.leprae_Br4923          YAVNVVLTTIGVRFGTGH
MAB_4155c|M.abscessus_ATCC_199      FVINVVMTAIGVRVLVKH
                                    :. **::*:****. .