For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
YDELLANLAILVLSGFVGFAVISKVPNTLHTPLMSGTNAIHGIVVLGALVVFGEVEHPSLAVQIILFVAV VFGTLNVIGGFIVTDRMLGMFKGKKKVAAVKAEKAEGSAAK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4734 | pntAb | - | 100% (112) | NAD(P) transhydrogenase (subunit alpha) PntAb |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0161 | pntAb | 1e-46 | 84.11% (107) | NAD(P) transhydrogenase subunit alpha |
| M. gilvum PYR-GCK | Mflv_0726 | pntA | 6e-16 | 43.82% (89) | NAD(P) transhydrogenase subunit alpha |
| M. tuberculosis H37Rv | Rv0156 | pntAb | 1e-47 | 85.05% (107) | NAD(P) transhydrogenase subunit alpha |
| M. leprae Br4923 | MLBr_02635 | pntAB | 2e-52 | 91.07% (112) | pyridine transhydrogenase subunit alpha2 |
| M. abscessus ATCC 19977 | MAB_4578c | - | 5e-38 | 71.03% (107) | NAD(P) transhydrogenase, alpha2 subunit PntAB |
| M. marinum M | MMAR_0378 | pntAb | 1e-57 | 100.00% (112) | NAD(P) transhydrogenase (subunit alpha) PntAb |
| M. avium 104 | MAV_5141 | - | 1e-48 | 91.43% (105) | PntAB protein |
| M. smegmatis MC2 155 | MSMEG_0151 | - | 3e-39 | 74.34% (113) | PntAB protein |
| M. thermoresistible (build 8) | TH_0163 | pntAB | 5e-47 | 86.79% (106) | PROBABLE NAD(P) TRANSHYDROGENASE (SUBUNIT ALPHA) PNTAB |
| M. vanbaalenii PYR-1 | Mvan_0120 | pntA | 4e-17 | 45.45% (88) | NAD(P) transhydrogenase subunit alpha |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0161|M.bovis_AF2122/97 --------------------------------------------------
Rv0156|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4734|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0378|M.marinum_M --------------------------------------------------
MLBr_02635|M.leprae_Br4923 --------------------------------------------------
MAV_5141|M.avium_104 --------------------------------------------------
TH_0163|M.thermoresistible__bu --------------------------------------------------
MAB_4578c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0151|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0726|M.gilvum_PYR-GCK MIIGIPRESMPGETRVAATPQTVGQLVKLGYQVAVETGAGAASSFSDDAY
Mvan_0120|M.vanbaalenii_PYR-1 MIIGIPRESQPGETRVAATPQTVGQLIKLGYQVVVESGAGAAASFSDAAF
Mb0161|M.bovis_AF2122/97 --------------------------------------------------
Rv0156|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4734|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0378|M.marinum_M --------------------------------------------------
MLBr_02635|M.leprae_Br4923 --------------------------------------------------
MAV_5141|M.avium_104 --------------------------------------------------
TH_0163|M.thermoresistible__bu --------------------------------------------------
MAB_4578c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0151|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0726|M.gilvum_PYR-GCK TAAGATVGPNTEVLASDVVLKVNAPSEAEIAALRDGATLISLISPALKPE
Mvan_0120|M.vanbaalenii_PYR-1 AEAGAGIGSPDEVWSADVVLKVNAPTEAEIATLRDGATLIGLISPALRPE
Mb0161|M.bovis_AF2122/97 --------------------------------------------------
Rv0156|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4734|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0378|M.marinum_M --------------------------------------------------
MLBr_02635|M.leprae_Br4923 --------------------------------------------------
MAV_5141|M.avium_104 --------------------------------------------------
TH_0163|M.thermoresistible__bu --------------------------------------------------
MAB_4578c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0151|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0726|M.gilvum_PYR-GCK LVEQLATRPITVLAMDAVPRISRAQSLDVLSSMANIAGYRAVIEAAHKFG
Mvan_0120|M.vanbaalenii_PYR-1 LVEQLATRRITVLAMDAVPRISRAQSLDVLSSMANIAGYRAVVEAAHRFG
Mb0161|M.bovis_AF2122/97 --------------------------------------------------
Rv0156|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4734|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0378|M.marinum_M --------------------------------------------------
MLBr_02635|M.leprae_Br4923 --------------------------------------------------
MAV_5141|M.avium_104 --------------------------------------------------
TH_0163|M.thermoresistible__bu --------------------------------------------------
MAB_4578c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0151|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0726|M.gilvum_PYR-GCK RFFTGQVTAAGKVPPAKVLVVGAGVAGLAAIGAAGSLGAIVRATDPRPEV
Mvan_0120|M.vanbaalenii_PYR-1 RFFTGQVTAAGKVPPAKVLVVGAGVAGLAAIGAAGSLGAIVRATDPRPEV
Mb0161|M.bovis_AF2122/97 --------------------------------------------------
Rv0156|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4734|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0378|M.marinum_M --------------------------------------------------
MLBr_02635|M.leprae_Br4923 --------------------------------------------------
MAV_5141|M.avium_104 --------------------------------------------------
TH_0163|M.thermoresistible__bu --------------------------------------------------
MAB_4578c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0151|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0726|M.gilvum_PYR-GCK ADQVASLGGEYLAVDPAAAEVSATGYAKEMGDDYKAREAALYAEQCKDVD
Mvan_0120|M.vanbaalenii_PYR-1 ADQVRSLGGEYLSIESPEAEVSATGYAKEMGDDYKAREAQLYAQQSEDVD
Mb0161|M.bovis_AF2122/97 --------------------------------------------------
Rv0156|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4734|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0378|M.marinum_M --------------------------------------------------
MLBr_02635|M.leprae_Br4923 --------------------------------------------------
MAV_5141|M.avium_104 --------------------------------------------------
TH_0163|M.thermoresistible__bu --------------------------------------------------
MAB_4578c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0151|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0726|M.gilvum_PYR-GCK IIITTALIPGRPAPRIITAEMVASMKPGSVIVDMAAANGGNVEGTVKDEA
Mvan_0120|M.vanbaalenii_PYR-1 IIITTALIPGRPAPRIITADMVASMKSGSVIVDMAAANGGNVEGTVKDQA
Mb0161|M.bovis_AF2122/97 --------------------------------------------------
Rv0156|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4734|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0378|M.marinum_M --------------------------------------------------
MLBr_02635|M.leprae_Br4923 --------------------------------------------------
MAV_5141|M.avium_104 --------------------------------------------------
TH_0163|M.thermoresistible__bu --------------------------------------------------
MAB_4578c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0151|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0726|M.gilvum_PYR-GCK VVTANGVTIIGYTDLAGRLPAQSSQLYGTNLVNLLKLLTPEKDGQLTLDW
Mvan_0120|M.vanbaalenii_PYR-1 VVTDNGVTIIGYTDLAGRLPTQASQLYGTNLVNLLKLLTPEKDGQLTVDF
Mb0161|M.bovis_AF2122/97 --------------------------------------------------
Rv0156|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4734|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0378|M.marinum_M --------------------------------------------------
MLBr_02635|M.leprae_Br4923 --------------------------------------------------
MAV_5141|M.avium_104 --------------------------------------------------
TH_0163|M.thermoresistible__bu --------------------------------------------------
MAB_4578c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0151|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0726|M.gilvum_PYR-GCK DDVVQRSVTVVRGGEITWPPPPVQVSAAPAAAVAATPVEPKPAKKPMTTA
Mvan_0120|M.vanbaalenii_PYR-1 DDVVQRSVTVVRDGEITWPPPPVQVSAAPVAAAAA-PVEQKPAKKPMTTG
Mb0161|M.bovis_AF2122/97 -------------------MCNELLENLAILVLSGFVGFAVISKVPNTLH
Rv0156|M.tuberculosis_H37Rv -------------------MYNELLENLAILVLSGFVGFAVISKVPNTLH
MUL_4734|M.ulcerans_Agy99 -------------------MYDELLANLAILVLSGFVGFAVISKVPNTLH
MMAR_0378|M.marinum_M -------------------MYDELLANLAILVLSGFVGFAVISKVPNTLH
MLBr_02635|M.leprae_Br4923 -------------------MYDELLANLAILVLSGFVGFAVISKVPNTLH
MAV_5141|M.avium_104 -------------------MYDELLANLAILVLSGFVGFAVISKVPNTLH
TH_0163|M.thermoresistible__bu -------------------MYDELLANLAILVLSGFVGFAVISKVPNTLH
MAB_4578c|M.abscessus_ATCC_199 -------------------MYGQLLANIAILVLAGFVGFAVISKVPNTLH
MSMEG_0151|M.smegmatis_MC2_155 -------------------MYDQLLANLAILVLAGFVGFAVISKVPNTLH
Mflv_0726|M.gilvum_PYR-GCK RRLGVTFGVAAALLLLIALSPAALQVHLTVFALAIVIGYYVIGNVHHALH
Mvan_0120|M.vanbaalenii_PYR-1 RRLGVTFAVAAALFVLIALSPAALQVHLTVFALAIVIGYYVIGNVHHALH
* :::::.*: .:*: **.:* ::**
Mb0161|M.bovis_AF2122/97 TPLMSGTNAIHGIVVLGALVVFGEI-EHPSLVLQVILFVAVVFGTLNVIG
Rv0156|M.tuberculosis_H37Rv TPLMSGTNAIHGIVVLGALVVFGEI-EHPSLVLQVILFVAVVFGTLNVIG
MUL_4734|M.ulcerans_Agy99 TPLMSGTNAIHGIVVLGALVVFGEV-EHPSLAVQIILFVAVVFGTLNVIG
MMAR_0378|M.marinum_M TPLMSGTNAIHGIVVLGALVVFGEV-EHPSLAVQIILFVAVVFGTLNVIG
MLBr_02635|M.leprae_Br4923 TPLMSGTNAIHGIVLLGALVVFGEV-AQPSLAVQIILFVAVVFGTLNVIG
MAV_5141|M.avium_104 TPLMSGTNAIHGIVVLGALVVFGSV-EHPSLAMQIILFVAVVFGTLNVIG
TH_0163|M.thermoresistible__bu TPLMSGTNAIHGIVVLGALVVLGKV-ENPSLAMQIILFVAVVFGTLNVVG
MAB_4578c|M.abscessus_ATCC_199 TPLMSGTNAIHGIVVLGALIVLGNLPADASWGTRVIAFVALIFGTLNVIG
MSMEG_0151|M.smegmatis_MC2_155 TPLMSGTNAIHGIVVLGALIVLGDLPADASWGVRIIAFVALVFGTLNVIG
Mflv_0726|M.gilvum_PYR-GCK TPLMSVTNAISGIIVVGALLQIGHDLDSGGALITGLAFVAILLASINIFG
Mvan_0120|M.vanbaalenii_PYR-1 TPLMSVTNAISGIIVVGALLQIGH----GNIAITALAFAAILLASINIFG
***** **** **:::***: :* . : *.*:::.::*:.*
Mb0161|M.bovis_AF2122/97 GFIVTDRMLGMFKAKKPAVPAKPDRDEALR--
Rv0156|M.tuberculosis_H37Rv GFIVTDRMLGMFKAKKPAVPAKPDRDEALR--
MUL_4734|M.ulcerans_Agy99 GFIVTDRMLGMFKGKKKVAAVKAEKAEGSAAK
MMAR_0378|M.marinum_M GFIVTDRMLGMFKGKKKVAAVKAEKAEGSAAK
MLBr_02635|M.leprae_Br4923 GFIVTDRMLGMFRGKKKASAVKTEKAAESVAK
MAV_5141|M.avium_104 GFIVTDRMLGMFKSKK---PAKADEAAK----
TH_0163|M.thermoresistible__bu GFVVTDRMLGMFKTRKP-VAVEAEESAR----
MAB_4578c|M.abscessus_ATCC_199 GFLVTDRMLGMFKSKKPAQSEQQKEAAK----
MSMEG_0151|M.smegmatis_MC2_155 GFLVTDRMLGMFKTRKPE--VREAEAAK----
Mflv_0726|M.gilvum_PYR-GCK GFAVTRRMLAMFSRS-----------------
Mvan_0120|M.vanbaalenii_PYR-1 GFAVTRRMLAMFSRS-----------------
** ** ***.**