For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
LARSPSWSIALRRVRGRLRTVCALLRPVSWNPVNTSSAPKSQAPINRRMALMALGAGVLAPNVLAACSGK VAKQAEQKAPEAPRLIFRPTDAAGDVLPIDPVSIEVGNGWFQRVVLKNPSGKVIAGAYNQERTVYTVTEP LGYDTTYTWSGAAVGHDGKAIPVGGKFTTVTPDKQIDGGFQLADGQIVGIAAPVIIQFDAPITDKATVER ALHVTTNPPVEGSWAWLPDEAKGARVHWRPREYYPAGTTVSVDAKLYGLPFGDGAYGAQDMTLNFQIGRR QIVKAEVPSHRIQVVTDEGVIMDFPCSYGEADLARNVTRNGVHVVTEKYSDFYMSNPAAGYSNVHERWAV RISNNGEFIHANPQSAGAQGNSNVTNGCINLSTSNAEEYFHSAIYGDPVEVTGSTIELSYSDGDIWDWAV DWGTWLSMSALPAPSARTPGTQIPITAPATPSTAPSLSGTPTTPSTTTPGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4553 | lprQ | - | 100% (471) | lipoprotein LprQ |
| M. ulcerans Agy99 | MUL_3804 | lppS | 4e-51 | 30.96% (407) | lipoprotein LppS |
| M. ulcerans Agy99 | MUL_1085 | - | 3e-33 | 34.54% (249) | secretory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0493 | lprQ | 0.0 | 80.13% (448) | lipoprotein LprQ |
| M. gilvum PYR-GCK | Mflv_0089 | - | 1e-160 | 63.28% (433) | ErfK/YbiS/YcfS/YnhG family protein |
| M. tuberculosis H37Rv | Rv0483 | lprQ | 0.0 | 80.13% (448) | lipoprotein LprQ |
| M. leprae Br4923 | MLBr_02446 | - | 0.0 | 74.38% (441) | putative lipoprotein |
| M. abscessus ATCC 19977 | MAB_4061c | - | 1e-162 | 64.73% (431) | hypothetical protein MAB_4061c |
| M. marinum M | MMAR_0809 | lprQ | 0.0 | 99.13% (461) | lipoprotein LprQ |
| M. avium 104 | MAV_4666 | - | 0.0 | 74.89% (446) | ErfK/YbiS/YcfS/YnhG family protein |
| M. smegmatis MC2 155 | MSMEG_0929 | - | 1e-169 | 64.76% (454) | ErfK/YbiS/YcfS/YnhG family protein |
| M. thermoresistible (build 8) | TH_3211 | - | 1e-161 | 64.19% (430) | PUTATIVE ErfK/YbiS/YcfS/YnhG family protein |
| M. vanbaalenii PYR-1 | Mvan_0824 | - | 1e-166 | 65.59% (433) | ErfK/YbiS/YcfS/YnhG family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0089|M.gilvum_PYR-GCK -----------------------MSPA------------DPLPSITRRRA
Mvan_0824|M.vanbaalenii_PYR-1 -----------------------MSPA------------EPLPWMTRRRA
MSMEG_0929|M.smegmatis_MC2_155 -----------------------MSPAGDDQAEISADRQAPAPLMNRRRA
TH_3211|M.thermoresistible__bu -----------------------VTPSG-ASAGPDGRDRHGPPVLNRRRA
MUL_4553|M.ulcerans_Agy99 MARSPSWSIALRRVRGRLRTVCALLRPVSWNPVNTSSAPKSQAPINRRMA
MMAR_0809|M.marinum_M ---------MLRRVRGRLRTVCALLRPVSWNPVNTSSAPKSQAPINRRMA
Mb0493|M.bovis_AF2122/97 ------------------MVIRVLFRPVSLIPVNNSSTPQSQGPISRRLA
Rv0483|M.tuberculosis_H37Rv ------------------MVIRVLFRPVSLIPVNNSSTPQSQGPISRRLA
MLBr_02446|M.leprae_Br4923 --------------------------------MIASTPRQNRESINRRVA
MAV_4666|M.avium_104 -----------------------------------MTPSSAPRPFNRRVA
MAB_4061c|M.abscessus_ATCC_199 ---------------------------------MKYPRPHLGDALTRRRA
:.** *
Mflv_0089|M.gilvum_PYR-GCK LAAFAVGIVAPATLAACMS-DGGGTGAENADEAPQAPTVSYEPADGSSDV
Mvan_0824|M.vanbaalenii_PYR-1 LAALAVGVVAPGTLAACMSGDKTSTDGVAAEDAPKEPTVTYQPADAAEDV
MSMEG_0929|M.smegmatis_MC2_155 LTALAVGMGA-GVLAACSG-KTPLSSQDEPEAAPAEPTLKYSPEPDTVDV
TH_3211|M.thermoresistible__bu LGLLALGVTAPAALAACVG--------DVGSPAEPTPALTFEPAADSVDV
MUL_4553|M.ulcerans_Agy99 LMALGAGVLAPNVLAACSG----KVAKQAEQKAPEAPRLIFRPTDAAGDV
MMAR_0809|M.marinum_M LMALGAGVLAPNVLAACSG----KVAKQAEQKAPEAPRLIFRPTDAAGDV
Mb0493|M.bovis_AF2122/97 LTALGFGVLAPNVLVACAG----KVTKLAEKRPPPAPRLTFRPADSAADV
Rv0483|M.tuberculosis_H37Rv LTALGFGVLAPNVLVACAG----KVTKLAEKRPPPAPRLTFRPADSAADV
MLBr_02446|M.leprae_Br4923 LTALGVGVFAPSVFVACAG----SAIKPSEKKTTPAPHLTFQPATATDDV
MAV_4666|M.avium_104 LATLGIGALAPGVLAACGG----GTAKEAEKKEQPALRLKYQPADAAQNV
MAB_4061c|M.abscessus_ATCC_199 LTILGLTVPAVAAACTTVG------SNQPEEAPSPGASLTFLPDDKAKDV
* :. * . : . . : : * : :*
Mflv_0089|M.gilvum_PYR-GCK APKGAVGVTVENGWFQKVSLVNANTGKVVAGTLDKDRTTFTVTESLGYGA
Mvan_0824|M.vanbaalenii_PYR-1 APTGNVGVEVADGWFQKVTLTNAG-GKTVAGSLNRDRTAFTITEPLGYGT
MSMEG_0929|M.smegmatis_MC2_155 LPTSEVGIEISDGWIQKIALTNAS-GKVVSGRLNQDRTAFTITEPLGYDA
TH_3211|M.thermoresistible__bu LPTAPVRAVVADGRFDRISLTNPD-GKVVAGVLNPDRTVFTTTEPLGYGR
MUL_4553|M.ulcerans_Agy99 LPIDPVSIEVGNGWFQRVVLKNPS-GKVIAGAYNQERTVYTVTEPLGYDT
MMAR_0809|M.marinum_M LPIDPVSVEVGNGWFQRVVLKNPS-GKVIAGAYNQERTVYTVTEPLGYDT
Mb0493|M.bovis_AF2122/97 VPIAPISVEVGDGWFQRVALTNSA-GKVVAGAYSRDRTIYTITEPLGYDT
Rv0483|M.tuberculosis_H37Rv VPIAPISVEVGDGWFQRVALTNSA-GKVVAGAYSRDRTIYTITEPLGYDT
MLBr_02446|M.leprae_Br4923 IPVAPISVQIADGWFQRVTLTNPV-GKVVAGVFNQDRTVYTITEPLGYDT
MAV_4666|M.avium_104 VPTAPVSVEVSDGWFQHVTLSNSS-GKAVAGTFNSDRTVYTTTEPLGYDQ
MAB_4061c|M.abscessus_ATCC_199 NPTAPVSVTVTNGWFRDVKLVNAD-GKVVAGALSRDQTRFHTTEPLGFDV
* : : :* : : * *. **.::* . ::* : **.**:.
Mflv_0089|M.gilvum_PYR-GCK DYEWSGSVVGEDGKAVPLSGSFTTVAPTTEVNGRFQLADGQTVGVAAPII
Mvan_0824|M.vanbaalenii_PYR-1 TYTWAGTVVGNDGKAVPLAGSFTTVDPTSQVSGRFQLADGQTVGVAAPII
MSMEG_0929|M.smegmatis_MC2_155 TYTWSGSVVGEDGKTVPIEGKFTTVTPQTQVSGQFQLADGQVVGVAAPII
TH_3211|M.thermoresistible__bu TYTWAGTAVGPDGREVPVAGAFTTVAPAVQVTGRFQLADGQVVGVAAPII
MUL_4553|M.ulcerans_Agy99 TYTWSGAAVGHDGKAIPVGGKFTTVTPDKQIDGGFQLADGQIVGIAAPVI
MMAR_0809|M.marinum_M TYTWSGAAVGHDGKAIPVGGKFTTVTPDKQIDGGFQLADGQTVGIAAPVI
Mb0493|M.bovis_AF2122/97 TYTWSGSAVGHDGKAVPVAGKFTTVAPVKTINAGFQLADGQTVGIAAPVI
Rv0483|M.tuberculosis_H37Rv TYTWSGSAVGHDGKAVPVAGKFTTVAPVKTINAGFQLADGQTVGIAAPVI
MLBr_02446|M.leprae_Br4923 TYTWNGSAVGHDGKAVPVTGKFSTVTPVKKVNGGFQLADGQTVGVAAPII
MAV_4666|M.avium_104 TYTWSGSAVGHDGKTVAVAGKFSTVSPSKKISGAFQLADGQTVGIAAPII
MAB_4061c|M.abscessus_ATCC_199 KYTWKGSAVGLDGKAVPVSGAFTTLVPTAKVNGQFQLADGQTVGIAAPVI
* * *:.** **: :.: * *:*: * : . ******* **:***:*
Mflv_0089|M.gilvum_PYR-GCK LQFDAAIADADRAEVEKAVTVTTTPPVEGSWAWLPDEAGGSRMHWRTREY
Mvan_0824|M.vanbaalenii_PYR-1 MQFDAAIAEDDRAEVEKALKVTTTPPVEGGWAWLPDEAGGSRVHWRTREY
MSMEG_0929|M.smegmatis_MC2_155 LQFDASIDDQYRATVERALSVVTEPPVEGSWAWLPDEAAGSRVHWRSREY
TH_3211|M.thermoresistible__bu LQFDAPVG--DKAAVERALRVTTEPAVEGGWAWLPDEAAGSRVHWRPREY
MUL_4553|M.ulcerans_Agy99 IQFDAPIT--DKATVERALHVTTNPPVEGSWAWLPDEAKGARVHWRPREY
MMAR_0809|M.marinum_M IQFDAPIT--DKATVERALHVTTNPPVEGSWAWLPDEAKGARVHWRPREY
Mb0493|M.bovis_AF2122/97 IQFDSPIS--DKAAVERALTVTTDPPVEGGWAWLPDEAQGARVHWRPREY
Rv0483|M.tuberculosis_H37Rv IQFDSPIS--DKAAVERALTVTTDPPVEGGWAWLPDEAQGARVHWRPREY
MLBr_02446|M.leprae_Br4923 IQFDAPIS--DKSAVEKALTVTTTPPVEGSWAWLPDEAKGARIHYRPREY
MAV_4666|M.avium_104 LQFDAPIS--DKAAVEKALTVTTNPPVEGSWAWLPDEAQGARAHWRTREY
MAB_4061c|M.abscessus_ATCC_199 IQFDAHIA--DKAAVERSLSISCDPPTEGGWAWLPDEAQGSRVHWRSREY
:***: : :: **::: : *..**.******** *:* *:*.***
Mflv_0089|M.gilvum_PYR-GCK YPAGATVHVDADLYGVPFGDGAYGAADSTLDFTVGRFQVVKAEASSHRIQ
Mvan_0824|M.vanbaalenii_PYR-1 YPAGTTVHVDAKLYGVPFGDGAYGATDSTLDFSVGRFQVVKAEASSHRIQ
MSMEG_0929|M.smegmatis_MC2_155 FPAGTKVHVKAPLYGVEFGDGAYGAADATLDFEIGRKQVVKAEASSHRIQ
TH_3211|M.thermoresistible__bu YPAGTRVHVDAPLYGVAFGSGAFGAADATLDFSIGRYQLVRAHAPAHRLQ
MUL_4553|M.ulcerans_Agy99 YPAGTTVSVDAKLYGLPFGDGAYGAQDMTLNFQIGRRQIVKAEVPSHRIQ
MMAR_0809|M.marinum_M YPAGTTVSVDAKLYGLPFGDGAYGAQDMTLNFQIGRRQIVKAEVPSHRIQ
Mb0493|M.bovis_AF2122/97 YPAGTTVDVDAKLYGLPFGDGAYGAQDMSLHFQIGRRQVVKAEVSSHRIQ
Rv0483|M.tuberculosis_H37Rv YPAGTTVDVDAKLYGLPFGDGAYGAQDMSLHFQIGRRQVVKAEVSSHRIQ
MLBr_02446|M.leprae_Br4923 YPAGTTVNVDAKLYGLPFGDGAYGLQDMSLNIQIGRRQVVKAEVSSHRIQ
MAV_4666|M.avium_104 YPAGTTVNVQAKLYGLPFGDGAYGAEDISLNINIGRRQIVKAEVSSHRIQ
MAB_4061c|M.abscessus_ATCC_199 FKAGTKVEVKANLYGIPFGDGAFGNEDMSLDFSVGRRQVVYADAQSHRIR
: **: * *.* ***: **.**:* * :*.: :** *:* *.. :**::
Mflv_0089|M.gilvum_PYR-GCK VITDAG-VIMDFPCSYGEGDLDRNVTRSGIHVVTEKYEDFYMTNPAAGYA
Mvan_0824|M.vanbaalenii_PYR-1 VITDAG-VIMDFPCSYGEGDLDRNVTRSGIHVVTEKYEDFYMTNPAAGYA
MSMEG_0929|M.smegmatis_MC2_155 VLDGAGAVIMDFPCSYGEGDLDRNVTRSGIHVVTEKYEDFYMTNPAAGYA
TH_3211|M.thermoresistible__bu VLTDAG-VVMDFPCSYGEGNLPRNITRSGIHVVTEKHTDFYMSNPAAGYA
MUL_4553|M.ulcerans_Agy99 VVTDEG-VIMDFPCSYGEADLARNVTRNGVHVVTEKYSDFYMSNPAAGYS
MMAR_0809|M.marinum_M VVTDEG-VIMDFPCSYGEADLARNVTRNGVHVVTEKYSDFYMSNPAAGYS
Mb0493|M.bovis_AF2122/97 VVTDAG-VIMDFPCSYGEADLARNVTRNGIHVVTEKYSDFYMSNPAAGYS
Rv0483|M.tuberculosis_H37Rv VVTDAG-VIMDFPCSYGEADLARNVTRNGIHVVTEKYSDFYMSNPAAGYS
MLBr_02446|M.leprae_Br4923 VVTDAG-VIMDFPCSYGEADQARNVTRNGIHVVTEKYSDFYMSNPAAGYS
MAV_4666|M.avium_104 VIRDEG-VIMDFPCSYGEADKARNVTRNGIHVVSEKYADFYMSNPAAGYS
MAB_4061c|M.abscessus_ATCC_199 VTTDEG-TILDLPCSYGEGDLPRNVTRSGIHVVTEKYEDFWMSNPAAGYS
* . * .::*:******.: **:**.*:***:**: **:*:******:
Mflv_0089|M.gilvum_PYR-GCK NVRERFAVRISNNGEFIHANPASLGSQGNSNVTNGCINLSESDAQQYFNT
Mvan_0824|M.vanbaalenii_PYR-1 NVRERFAVRISNNGEFIHANPASSGAQGNSNVTNGCINLSLEDAEQYFNV
MSMEG_0929|M.smegmatis_MC2_155 NVHERFAVRISNNGEFIHCNPNSIGAQGNTNVTNGCINLNLENSQQYFNS
TH_3211|M.thermoresistible__bu NVHMRHAVRISNNGEFIHANPGSIGAQGNSNVTNGCINMSPADAEQYFHS
MUL_4553|M.ulcerans_Agy99 NVHERWAVRISNNGEFIHANPQSAGAQGNSNVTNGCINLSTSNAEEYFHS
MMAR_0809|M.marinum_M NVHERWAVRISNNGEFIHANPQSAGAQGNSNVTNGCINLSTSNAEEYFHS
Mb0493|M.bovis_AF2122/97 HIHERWAVRISNNGEFIHANPMSAGAQGNSNVTNGCINLSTENAEQYYRS
Rv0483|M.tuberculosis_H37Rv HIHERWAVRISNNGEFIHANPMSAGAQGNSNVTNGCINLSTENAEQYYRS
MLBr_02446|M.leprae_Br4923 NVYERWAVRISNNGEFIHANPASVGAQGNTNVTNGCINLSTGDAEQFYRS
MAV_4666|M.avium_104 HVHERWAVRISNNGEFIHANPASAGAQGNTNVTNGCINLSTSDAEQYYQS
MAB_4061c|M.abscessus_ATCC_199 NVHERFAVRISNNGEFIHANPNTIGQQGNTNVTNGCINLSLGDAESYFRT
:: * ************.** : * ***:********:. :::.::.
Mflv_0089|M.gilvum_PYR-GCK AIYGDPVEVTGTRIQLSYADGDIWDWAVPWDEWTSMSALSS---------
Mvan_0824|M.vanbaalenii_PYR-1 AMYGDPVEVTGTRLQLSYEDGDIWDWAVPWDEWVAMSALSE---------
MSMEG_0929|M.smegmatis_MC2_155 AIYGDPVEVTGTRIQLSYADGDIWDWAVDWDEWKSMSALSD---------
TH_3211|M.thermoresistible__bu AVYGDPVEVTGTSIPLSHADGDIWDWTVPWADWLAMSAIST---------
MUL_4553|M.ulcerans_Agy99 AIYGDPVEVTGSTIELSYSDGDIWDWAVDWGTWLSMSALPA------PSA
MMAR_0809|M.marinum_M AIYGDPVEVTGSTIELSYSDGDIWDWAVDWDTWLSMSALPA------PSA
Mb0493|M.bovis_AF2122/97 AVYGDPVEVTGSSIQLSYADGDIWDWAVDWDTWVSMSALPP------PAA
Rv0483|M.tuberculosis_H37Rv AVYGDPVEVTGSSIQLSYADGDIWDWAVDWDTWVSMSALPP------PAA
MLBr_02446|M.leprae_Br4923 AIYGDPVEVTGSSIQLSYSDGDIWDWAVDWDTWVGMSALLSF-----PTV
MAV_4666|M.avium_104 AIYGDPVEVTGSSIQLSYADGDIWDWAVDWDTWVAMSALPP------PTA
MAB_4061c|M.abscessus_ATCC_199 AIYGDPVEVTGTSIELSYADGDLWDWVVDWPTWQSMSALPPNPRERTVTS
*:*********: : **: ***:***.* * * .***:
Mflv_0089|M.gilvum_PYR-GCK ADRTDDIPSSAPVTPSGAPQPAGA----------------RPGG---
Mvan_0824|M.vanbaalenii_PYR-1 QESPTGIPSTAPVTPSEAPQPVGD----------------RPGG---
MSMEG_0929|M.smegmatis_MC2_155 TRAPSDIPASAPATPSDAPTLSGTPTTT-------APPEPAPGG---
TH_3211|M.thermoresistible__bu GPAPPDLPESAPATPPDAPVTTPR-----------------PGG---
MUL_4553|M.ulcerans_Agy99 RTPGTQIPITAPATPSTAPSLSGTPTTP---------STTTPGG---
MMAR_0809|M.marinum_M RTPATQIPITAPATPSTAPSLSGTPTTP---------STTTPGG---
Mb0493|M.bovis_AF2122/97 KPAATQIPVTAPVTPSDAPTPSGTPTT-----------TNGPGG---
Rv0483|M.tuberculosis_H37Rv KPAATQIPVTAPVTPSDAPTPSGTPTT-----------TNGPGG---
MLBr_02446|M.leprae_Br4923 HQPATQIPVTAPVTPPGAPILSGTPTS--------GSGTARPGG---
MAV_4666|M.avium_104 HPPSTQIPVTAPVTPSNAPTLSGTPTTSTTTPA--STGPATPGG---
MAB_4061c|M.abscessus_ATCC_199 SPATSSIPTTVPLTPSGAPTLSGTPTSTPSTTSGAPSLSATPTTTRR
:* :.* **. ** *