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M. ulcerans Agy99 MUL_4204 (ppa)

annotation: inorganic pyrophosphatase Ppa
coordinates: 4675796 - 4676284
length: 162

MQFDVTIEIPKGQHNKYEVDHETGRVKLDRYLYTPMAYPTDYGFIEDTLGEDGDPLDALVLLPEPLFPGV
LVEARPVGMFRMVDEKGGDDKVLCVPAGDHRWDHIQDIDNVPAFELEAIKHFFVHYKDLEPGKFVKAADW
VGREEAEAEVLRSVERFKTDGH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_4204ppa-100% (162)inorganic pyrophosphatase Ppa

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3652ppa4e-8488.27% (162) inorganic pyrophosphatase
M. gilvum PYR-GCKMflv_1408-2e-7782.72% (162) inorganic diphosphatase
M. tuberculosis H37RvRv3628ppa4e-8488.27% (162) inorganic pyrophosphatase
M. leprae Br4923MLBr_00210ppa7e-8689.51% (162) putative inorganic pyrophosphatase
M. abscessus ATCC 19977MAB_0518c-3e-8184.57% (162) inorganic pyrophosphatase
M. marinum MMMAR_5128ppa9e-9599.38% (162) inorganic pyrophosphatase Ppa
M. avium 104MAV_0527ppa1e-8285.19% (162) inorganic pyrophosphatase
M. smegmatis MC2 155MSMEG_6114ppa7e-7779.63% (162) inorganic pyrophosphatase
M. thermoresistible (build 8)TH_1414ppa4e-7881.48% (162) INORGANIC PYROPHOSPHATASE PPA (PYROPHOSPHATE
M. vanbaalenii PYR-1Mvan_5381-1e-7782.72% (162) inorganic diphosphatase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1408|M.gilvum_PYR-GCK          MQFDVLIEIQKGSRNKYEVDHESGKVKLDRYLFTSFGYPTDYGYIEDTLG
Mvan_5381|M.vanbaalenii_PYR-1       MQFDVLIEIQKGSRNKYEVDHDSGKVKLDRYLFTSFGYPTDYGYIEDTLG
MUL_4204|M.ulcerans_Agy99           MQFDVTIEIPKGQHNKYEVDHETGRVKLDRYLYTPMAYPTDYGFIEDTLG
MMAR_5128|M.marinum_M               MQFDVTIEIPKGQRNKYEVDHETGRVKLDRYLYTPMAYPTDYGFIEDTLG
MLBr_00210|M.leprae_Br4923          MQFDVTIEIPKGQRNKYEVDHKTGRVRLDRYLYTPMAYPTDYGFIEDTLG
Mb3652|M.bovis_AF2122/97            MQFDVTIEIPKGQRNKYEVDHETGRVRLDRYLYTPMAYPTDYGFIEDTLG
Rv3628|M.tuberculosis_H37Rv         MQFDVTIEIPKGQRNKYEVDHETGRVRLDRYLYTPMAYPTDYGFIEDTLG
MAB_0518c|M.abscessus_ATCC_199      MEFDVTIEIPKGQRNKYEVDHETGRVRLDRFLYTPMAYPTDYGFIENTLG
MAV_0527|M.avium_104                MEFDVTIEILKGQRNKYEVDHETGRLRLDRYLYTAMAYPTDYGFIEDTLG
MSMEG_6114|M.smegmatis_MC2_155      MEFDVVIEIPKGSRNKYEVDHETGRVKLDRYLYTPMGYPTDYGFFENTLG
TH_1414|M.thermoresistible__bu      VQFDVVIEIPKGSRNKYEVDHETGKIKLDRYLFTPMAYPADYGFIEDSLG
                                    ::*** *** **.:*******.:*:::***:*:*.:.**:***::*::**

Mflv_1408|M.gilvum_PYR-GCK          EDGDPLDALVLLPEPVFPGCIVEARPVGMFRMEDEKGGDDKVLCVLA-DP
Mvan_5381|M.vanbaalenii_PYR-1       EDGDPLDALVLLPEPVFPGCIVEARPVGMFRMTDEKGGDDKVLCVLA-DP
MUL_4204|M.ulcerans_Agy99           EDGDPLDALVLLPEPLFPGVLVEARPVGMFRMVDEKGGDDKVLCVPAGDH
MMAR_5128|M.marinum_M               EDGDPLDALVLLPEPLFPGVLVEARPVGMFRMVDEKGGDDKVLCVPAGDH
MLBr_00210|M.leprae_Br4923          EDGDPLDALVLLPEPLFPGVLVEARPVGMFRMVDEHGGDDKVLCVPVNDH
Mb3652|M.bovis_AF2122/97            DDGDPLDALVLLPQPVFPGVLVAARPVGMFRMVDEHGGDDKVLCVPAGDP
Rv3628|M.tuberculosis_H37Rv         DDGDPLDALVLLPQPVFPGVLVAARPVGMFRMVDEHGGDDKVLCVPAGDP
MAB_0518c|M.abscessus_ATCC_199      EDGDPLDALVLLPESVFPGVIVEARPVGMFKMVDDGGGDDKVLCVPAGDP
MAV_0527|M.avium_104                EDGDPLDAMVLLPQSVFPGVIVEARPVGMFRMTDEKGGDDKVLCVPAGDH
MSMEG_6114|M.smegmatis_MC2_155      EDGDPLDALVLLTESVFPGCVVEARPVAMFKMTDEAGGDDKLLCVPAGDP
TH_1414|M.thermoresistible__bu      EDGDPLDALVLLPEPVFPGVVVEARPVAMFRMTDEAGGDDKVLCVPAGDP
                                    :*******:***.:.:*** :* ****.**:* *: *****:*** . * 

Mflv_1408|M.gilvum_PYR-GCK          RWDHIQDIGDVSDFELDAIKHFFVHYKDLEPGKFVKAADWVGREEAEAEI
Mvan_5381|M.vanbaalenii_PYR-1       RWDHIQDIGDVSDFELDAIKHFFVHYKDLEPGKFVKAADWVGREKAEAEV
MUL_4204|M.ulcerans_Agy99           RWDHIQDIDNVPAFELEAIKHFFVHYKDLEPGKFVKAADWVGREEAEAEV
MMAR_5128|M.marinum_M               RWDHIQDIDNVPAFELEAIKHFFVHYKDLEPGKFVKAADWVGREEAEAEV
MLBr_00210|M.leprae_Br4923          RWDHIHGIIDVPTFELDAIKHFFVHYKDLEPGKFVKAADWVGRDEAEAEV
Mb3652|M.bovis_AF2122/97            RWDHVQDIGDVPAFELDAIKHFFVHYKDLEPGKFVKAADWVDRAEAEAEV
Rv3628|M.tuberculosis_H37Rv         RWDHVQDIGDVPAFELDAIKHFFVHYKDLEPGKFVKAADWVDRAEAEAEV
MAB_0518c|M.abscessus_ATCC_199      RWDHIQDIGDVSSFELDSIKHFFVHYKDLEPGKFVEAADWVGRAEAEAEV
MAV_0527|M.avium_104                RWEHIQDIGDVPEFELDVIKHFFVHYKDLEPGKFVKAADWVGRAEAEAEV
MSMEG_6114|M.smegmatis_MC2_155      RWDHIQDVGDISQFELDAIKHFFVHYKDLEPGKFVKTADWEGRAEAEAEL
TH_1414|M.thermoresistible__bu      RWDHITDLADVPSAELEAIKHFFVHYKDLEPGKYVKAADWAGRAEAEAEV
                                    **:*: .: ::.  **: ***************:*::*** .* :****:

Mflv_1408|M.gilvum_PYR-GCK          NRSIERFKTEGH
Mvan_5381|M.vanbaalenii_PYR-1       LRSIERFKTEGH
MUL_4204|M.ulcerans_Agy99           LRSVERFKTDGH
MMAR_5128|M.marinum_M               LRSVERFKTDGH
MLBr_00210|M.leprae_Br4923          QRSVERFKAGGH
Mb3652|M.bovis_AF2122/97            QRSVERFKAGTH
Rv3628|M.tuberculosis_H37Rv         QRSVERFKAGTH
MAB_0518c|M.abscessus_ATCC_199      LASFERLKTQGH
MAV_0527|M.avium_104                QRSIERFKAQGH
MSMEG_6114|M.smegmatis_MC2_155      QRSVERFKSSGH
TH_1414|M.thermoresistible__bu      QRSFERFAATQH
                                      *.**: :  *