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VLWSSVPGSPYLTEIKQARIGCISRLFGTGIAIDANVRESRAVQVRRFGELETVVMDRVWDHGGAVTVRG VFDDLAHDRQIAYTTVMSTMDNLHRKGWLQRERVGKAFSYWPTMTREEHSARLMHDAFDVGGDSDLVLAF FLNQMDEHDAVRVRDALRRIIDDQEES*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4136 | - | - | 100% (168) | transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_3033 | - | 4e-12 | 35.43% (127) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1877c | - | 2e-12 | 34.40% (125) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0896 | - | 2e-35 | 56.56% (122) | CopY family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1846c | - | 3e-12 | 34.40% (125) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02063 | - | 1e-14 | 36.80% (125) | putative regulator |
| M. abscessus ATCC 19977 | MAB_4858 | - | 2e-33 | 62.04% (108) | penicillinase repressor |
| M. marinum M | MMAR_5060 | - | 2e-61 | 97.32% (112) | transcriptional regulatory protein |
| M. avium 104 | MAV_2869 | - | 2e-12 | 31.50% (127) | transcriptional repressor, CopY family protein |
| M. smegmatis MC2 155 | MSMEG_3630 | - | 4e-14 | 37.19% (121) | transcriptional repressor, CopY family protein |
| M. thermoresistible (build 8) | TH_1064 | - | 5e-13 | 36.75% (117) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_5556 | - | 5e-38 | 61.54% (117) | CopY family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1877c|M.bovis_AF2122/97 ------------------------------------------MAKLTRLG
Rv1846c|M.tuberculosis_H37Rv ------------------------------------------MAKLTRLG
MAV_2869|M.avium_104 ------------------------------------------MAKLTRLG
MLBr_02063|M.leprae_Br4923 ------------------------------------------MAKLTRLG
MSMEG_3630|M.smegmatis_MC2_155 ---------------------------------------------MTRLG
TH_1064|M.thermoresistible__bu ---------------------------------------------MTRLG
MUL_4136|M.ulcerans_Agy99 MVLWSSVPGSPYLTEIKQARIGCISRLFGTGIAIDANVRESRAVQVRRFG
MMAR_5060|M.marinum_M --------------------------------------------------
Mflv_0896|M.gilvum_PYR-GCK --MPRCAHRPPRQSE-----------------------QELRRMEQRGFG
Mvan_5556|M.vanbaalenii_PYR-1 -------------------------------------------MGLRQFG
MAB_4858|M.abscessus_ATCC_1997 --------------------------------------------------
Mb1877c|M.bovis_AF2122/97 DLERAVMDHLWSRTE--PQTVRQVHEALSARRDLAYTTVMTVLQRLAKKN
Rv1846c|M.tuberculosis_H37Rv DLERAVMDHLWSRTE--PQTVRQVHEALSARRDLAYTTVMTVLQRLAKKN
MAV_2869|M.avium_104 DLERAVMDHLWSTAE--PQTVRQVHEALSAQRDLAYTTIMTVLQRLAKKN
MLBr_02063|M.leprae_Br4923 DLERAVMDHLWSRQE--PQTVRQVHEALSARRDLAYTTVMTVLQRLAKKN
MSMEG_3630|M.smegmatis_MC2_155 ELEREVMDHLWSAPE--PQTVRQVHEALAARRDLAYTTIMTVLQRLAKKN
TH_1064|M.thermoresistible__bu DLEHEVMDHLWSASE--PQTVRQVHEALAARRDLAYTTVMTVLHRLAKKK
MUL_4136|M.ulcerans_Agy99 ELETVVMDRVWDHGG--AVTVRGVFDDLAHDRQIAYTTVMSTMDNLHRKG
MMAR_5060|M.marinum_M ------MDRVWDHGG--AVTVRGVFDDLAHDRRIAYTTVMSTMDNLHRKG
Mflv_0896|M.gilvum_PYR-GCK DLEAVIMDWVWDHQE--PITVRDVFEDLSQQRPIAYTTVLSTMDNLYRKR
Mvan_5556|M.vanbaalenii_PYR-1 ELEAVVMDLLWSREG--ASTVRSVYDELRGSRQIAYTTVMSTMDNLFRKG
MAB_4858|M.abscessus_ATCC_1997 ----MVMDRVWSRGDETATTVREVFDELAAERDIAYTTVMSTMDNLHTKG
** :*. . *** *.: * * :****:::.:..* *
Mb1877c|M.bovis_AF2122/97 LVLQIRDDRAHRYAPVHGRDELVAGLMVDALAQAEYSGSRQAALVHFVER
Rv1846c|M.tuberculosis_H37Rv LVLQIRDDRAHRYAPVHGRDELVAGLMVDALAQAEDSGSRQAALVHFVER
MAV_2869|M.avium_104 LVSQIRDDRAHRYAPVHGRDELVAGLMVDALAQAEDSGSRQAALVHFVER
MLBr_02063|M.leprae_Br4923 LVSQIRNNRAHRYAPVHGRDELVAGLMVDALDQAEDSDSRQAALVHFVER
MSMEG_3630|M.smegmatis_MC2_155 LVVQHRDDRAHRYAPTHGRDELVAGLMVDALDQAADSGSRQAALVHFVER
TH_1064|M.thermoresistible__bu LVVQHRDDRAHRYAPAYGRDELVAGLMVDALDQASDSGSRQAALVHFVER
MUL_4136|M.ulcerans_Agy99 WLQRERVGKAFSYWPTMTREEHSARLMHDAFDVG---GDSDLVLAFFLNQ
MMAR_5060|M.marinum_M WLQRERVGKAFSYWPTMTREEHSARLMHDAFDAG---GDSDLVLAFFLKQ
Mflv_0896|M.gilvum_PYR-GCK WLKRQRNGKAYVYRAAMSREERSARLMKAAFDSG---GDTNTVLAFFVEQ
Mvan_5556|M.vanbaalenii_PYR-1 WLERDKVGLAYHYRPAMTREEHSANLMRTVFESG---GDGELILNFFLEQ
MAB_4858|M.abscessus_ATCC_1997 WLEREREGKAYRYWAALTREQHSARLMREALSGG---GSPELVLTHFLEQ
: : : . *. * .. *:: * ** .: . .. : * .*:::
Mb1877c|M.bovis_AF2122/97 VGADEADALRRALAELEAGHGNRPP-AGAATET---
Rv1846c|M.tuberculosis_H37Rv VGADEADALRRALAELEAGHGNRPP-AGAATET---
MAV_2869|M.avium_104 VGADEAEALRRALAELEANQRNNPASAGAGPEG---
MLBr_02063|M.leprae_Br4923 VGADEADALRRALAELETHQRHVRHLVALQRTTEGD
MSMEG_3630|M.smegmatis_MC2_155 VGVDEAAALRRALEELESKQRVLPPTGNSGTG----
TH_1064|M.thermoresistible__bu VGADEAEALRRALAELEAKHQDPPSTGGSGTD----
MUL_4136|M.ulcerans_Agy99 MDEHDAVRVRDALRRIIDDQEES-------------
MMAR_5060|M.marinum_M MDEHDAVRVRDALRRIIDDQEES-------------
Mflv_0896|M.gilvum_PYR-GCK MSTEQSAQLKAALR----KGRRS-------------
Mvan_5556|M.vanbaalenii_PYR-1 IGEDDSAKLRQAIRRSTRKGSR--------------
MAB_4858|M.abscessus_ATCC_1997 ISAEESERLRAVLRRPAKRARTK-------------
:. .:: :: .: