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APTSVSNARIEKAVLDAHEKQKNKHGGKNADYIPILAQVPSTLFGVSVATVDGQVFTAGDAGYEFALESI SKIFTLALVIEQRGPRELRLKVGADPTGEAFNSVLALELHNDKPMSPLVNAGAISTTSLVDAVGPEDRWR QIVGAQSDFAGRQISISEEINASEQATNFHNRAIAWLLRGSGYIYCDPMEACDIYTRQCSTLVTTADLAV MGATLANGGTNPITGKRVIARKNVPHVLAEMTMEGVYTRSGDWAYTVGLPAKSGVGGGLVAVAPGQLAIA AFSPPLDKVGNSVRAQAAVAQIADTLQLGLFNVPGEEDE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3484 | glsA | - | 100% (320) | glutaminase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2331 | - | 1e-63 | 44.25% (287) | glutaminase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_1548 | glsA | 0.0 | 100.00% (320) | glutaminase GlsA |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_3818 | - | 7e-34 | 35.02% (277) | thermolabile glutaminase |
| M. thermoresistible (build 8) | TH_2743 | - | 2e-64 | 42.76% (290) | PUTATIVE Glutaminase |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_3484|M.ulcerans_Agy99 MAPTSVSNARIEKAVLDAHEKQKNKHGGKNADYIPILAQVPSTLFGVSVA
MMAR_1548|M.marinum_M MAPTSVSNARIEKAVLDAHEKQKNKHGGKNADYIPILAQVPSTLFGVSVA
Mflv_2331|M.gilvum_PYR-GCK ------MAELVQRRLDRIRAEHAEVADGELADYIPELAGVDPDGFGLSLS
TH_2743|M.thermoresistible__bu ------VAELVQRYLDEILAEHADVTDGALADYIPELTRVDPSKFGLALE
MSMEG_3818|M.smegmatis_MC2_155 ---------MHEYLRAAELRGRRAALRGMVSRQIPALAAVPATRFAMAVA
: : * : ** *: * . *.:::
MUL_3484|M.ulcerans_Agy99 TVDGQVFTAGDAGYEFALESISKIFTLALVIEQRGPRELRLKVGADPTGE
MMAR_1548|M.marinum_M TVDGQVFTAGDAGYEFALESISKIFTLALVIEQRGPRELRLKVGADPTGE
Mflv_2331|M.gilvum_PYR-GCK TSDGFIYESGQAATEFTIQSISKPLTYALALHLIGLDAVDARIGVEPSGE
TH_2743|M.thermoresistible__bu LTDGFAYESGDARTQFTIQSISKPFTYALALDRIGHDAVDRKIGVEPSGE
MSMEG_3818|M.smegmatis_MC2_155 TVDGAEACIGEASTAFSIQSLSKLFALCALLRHEP--DVWTDVGWVPTDA
** *:* *:::*:** :: . : : :* *:.
MUL_3484|M.ulcerans_Agy99 AFNSVLALELHNDKPMSPLVNAGAISTTSLVDAVGPEDRWRQIVGAQSDF
MMAR_1548|M.marinum_M AFNSVLALELHNDKPMSPLVNAGAISTTSLVDAVGPEDRWRQIVGAQSDF
Mflv_2331|M.gilvum_PYR-GCK AFN-EISVDRVTNNPKNPMINAGAITAVSLIPAGSPDERFALIHDFYSAC
TH_2743|M.thermoresistible__bu PFN-EISVDDRTKTPKNPMINAGAIAAVSLIPAADPQERFAQILDFYSAC
MSMEG_3818|M.smegmatis_MC2_155 GYGSVADLERNHWRPRNPFVNSGALVVTDRLMTHAGDAVGATIEVLQAGD
:. :: * .*::*:**: ... : : : * :
MUL_3484|M.ulcerans_Agy99 AGRQISISEEINASEQATNFHNRAIAWLLRGSGYIYCDPMEACDIYTRQC
MMAR_1548|M.marinum_M AGRQISISEEINASEQATNFHNRAIAWLLRGSGYIYCDPMEACDIYTRQC
Mflv_2331|M.gilvum_PYR-GCK VGRRLELDHDVYTSEKASGARNRAIGYMLQSFGALDDDPDEVLDVYYRQC
TH_2743|M.thermoresistible__bu AGRPLDVDEDVYRSEKASNSRNRAIAYMLQSFGVLDDDPDDVLDVYVRQC
MSMEG_3818|M.smegmatis_MC2_155 PDAPVRSDPAVALSESEADHRNSAIAHVLAEHGRLVNDIDRVLPQYFAQC
. : . : **. :. :* **. :* * : * . * **
MUL_3484|M.ulcerans_Agy99 STLVTTADLAVMGATLANGGTNPITGKRVIARKNVPHVLAEMTMEGVYTR
MMAR_1548|M.marinum_M STLVTTADLAVMGATLANGGTNPITGKRVIARKNVPHVLAEMTMEGVYTR
Mflv_2331|M.gilvum_PYR-GCK SLRVTCTDLARMGATLARGGMNPVTGRRVTSAAVVRRTLSVMVTCGMYDG
TH_2743|M.thermoresistible__bu AIRVTSRDLAEMASTLARGGVHPATGRRVTSAAAVQRTLSVMMTCGMYDT
MSMEG_3818|M.smegmatis_MC2_155 AIAASVRTIARAALFLADR----TGERTVLDDDSVRRVNAVLLTSGMYGA
: .: :* . ** : * * :. : : *:*
MUL_3484|M.ulcerans_Agy99 SGDWAYTVGLPAKSGVGGGLVAVAPGQLAIAAFSPPLDKVGNSVRAQAAV
MMAR_1548|M.marinum_M SGDWAYTVGLPAKSGVGGGLVAVAPGQLAIAAFSPPLDKVGNSVRAQAAV
Mflv_2331|M.gilvum_PYR-GCK AGDWVSAVGMPAKSGVGGGIVAVLPGQLGIGVYSPRLDDKGNSVRGVLTC
TH_2743|M.thermoresistible__bu TGDWVTSVGMPAKSGVGGGILAVLPGQLGIGVYSPLLDENGNSVRGGRVC
MSMEG_3818|M.smegmatis_MC2_155 AGDIAYRIGLPAKSGIGGGVLAVMPGHGTVCVWSPPLDDDGNSAGGVAAI
:** . :*:*****:***::** **: : .:** **. ***. . .
MUL_3484|M.ulcerans_Agy99 AQIADTLQLGLFNVPGEEDE------------------------------
MMAR_1548|M.marinum_M AQIADTLQLGLFNVPGEEDE------------------------------
Mflv_2331|M.gilvum_PYR-GCK RSLSEQLGLHFLTVRRDARATLRAVYEPRPGVRVYEAHGDLLFSGAEEVL
TH_2743|M.thermoresistible__bu RTLSARLGLHFLSVTRESRSIIRATRDVAPRVRVYELHGDLLFAGAEQTL
MSMEG_3818|M.smegmatis_MC2_155 EEFARLAGWSVF--------------------------------------
:: .:
MUL_3484|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1548|M.marinum_M --------------------------------------------------
Mflv_2331|M.gilvum_PYR-GCK RVAERERDRYDVTILDVSRVDDIDDTAREMLSALGAALRADGKEGHLVDP
TH_2743|M.thermoresistible__bu RTVENDRADVDVAILEVSKVDDINDTARAMLAGMRESLTAVGKEGYVVDP
MSMEG_3818|M.smegmatis_MC2_155 --------------------------------------------------
MUL_3484|M.ulcerans_Agy99 ------------------------------------------
MMAR_1548|M.marinum_M ------------------------------------------
Mflv_2331|M.gilvum_PYR-GCK DG-VVARAGSPE--IRFRTVDDVLDALDRRRRPTP-------
TH_2743|M.thermoresistible__bu DRRVIPTDGRSAGAVVFGTVEDAIAAARDHVEIQAGSANRVG
MSMEG_3818|M.smegmatis_MC2_155 ------------------------------------------