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TAGEQYFDLGSYHRPVQTPSAQAQVWFDRAMVWAYAFNHEESIRCFERALDLDPGLAIARWGIAYAVGPN YNKPWVAFDPVDMTTSLARARMELSLAAQGRASPVDQGLVAALQARFPTDDPDDAEALRAGLGAYADAMA ELAAAYPADVDVQALAADALLNVTAWALWDTATGEPAAGSRVLEAKRLLDQALATPAGRAHPGILHLYLH AMEMSATPEVALPAADLLRGLVPDAGHLQHMPSHIDVLCGDYRSSVLANLAAVRADRRFVSREGPLNFYS LYRAHDLHFIVYSAMFEGQSQIALRAADELAGQLGAELLSIESPPMADWLEAFVPLRTHVLVRFGRWQEL IAQPLPCDRDLYCTTTATIHYGRGVALAATGQLAQAHAERVAFVEACARVPESRYLFNNTSRDILAVAAA MLDGEIAYRDGRFDEAFAHLRRAVTLDDTLPYDEPWGWMQPTRHAYGALLLEQGHVEEAAAVYAADLGLD PTLARPCQHPGNVWSLHGYHECLQRLGRTAEAAIIGQQLALAAARADVPIRASCACRVTACCDQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3298 | - | - | 100% (555) | hypothetical protein MUL_3298 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3331 | - | 0.0 | 77.22% (553) | TPR repeat-containing protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2051 | - | 0.0 | 99.10% (555) | hypothetical protein MMAR_2051 |
| M. avium 104 | MAV_0683 | - | 2e-35 | 26.82% (563) | hypothetical protein MAV_0683 |
| M. smegmatis MC2 155 | MSMEG_3574 | - | 0.0 | 76.84% (531) | TPR domain-containing protein |
| M. thermoresistible (build 8) | TH_2295 | - | 0.0 | 76.63% (552) | TPR domain protein |
| M. vanbaalenii PYR-1 | Mvan_3057 | - | 0.0 | 79.85% (551) | TPR repeat-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_3298|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2051|M.marinum_M --------------------------------------------------
Mflv_3331|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3057|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3574|M.smegmatis_MC2_155 --------------------------------------------------
TH_2295|M.thermoresistible__bu --------------------------------------------------
MAV_0683|M.avium_104 MFDAVRWRLSAGAMAVAVTVAACCAPSEPADPCMVASGAADESQGMDAMA
MUL_3298|M.ulcerans_Agy99 ----------MTAGEQYFDLGSYHRPVQTPSAQAQVWFDRAMVWAYAFNH
MMAR_2051|M.marinum_M ----------MTAGEQYFDLGSYHRPVQTPSAQAQVWFDRAMVWAYAFNH
Mflv_3331|M.gilvum_PYR-GCK MPCMNVASSAPGAAEPYYDLGSYHRPTDTASDAAQIWFDRGMVWSYAFNH
Mvan_3057|M.vanbaalenii_PYR-1 ---MSVAS---GSTEPYYDLGSFHRPTDTASDAAQVWFDRGMVWAYAFNH
MSMEG_3574|M.smegmatis_MC2_155 -----------------------------------MWFDRGMVWAYAFNH
TH_2295|M.thermoresistible__bu -------------MEPYFDLGSYHRAVPTTVRQAQVWCDRGMVWAYAFNH
MAV_0683|M.avium_104 MATEACPLVRLTENDPDPPLYPYLGSAHWHVPWAQEYFDQGLRFYFGFNN
: *:.: : :.**:
MUL_3298|M.ulcerans_Agy99 EESIRCFERALDLDPG----LAIARWGIAYAVGPNYNKPWVAFDPVDMTT
MMAR_2051|M.marinum_M EESIRCFERALDLDPG----LAIARWGIAYAVGPNYNKPWVAFDPVDMTT
Mflv_3331|M.gilvum_PYR-GCK EEAIHCFDRALELDPD----FALARWGVAYAIGPNYNKGWEAFDPVDLAA
Mvan_3057|M.vanbaalenii_PYR-1 EEAIHCFERALELDAD----LAMARWGIAYAIGPNYNKGREAFDPVDLAA
MSMEG_3574|M.smegmatis_MC2_155 GEAVYCFERALEYDPG----LAAAHWGIAYSVGPNYNKAWDAFDPVDLAA
TH_2295|M.thermoresistible__bu EEAVRCFERALRLDPD----LAAARWGIAYAAGPNYNKAWEAFDTADRTG
MAV_0683|M.avium_104 REAYRAFKKAARDAEDNDIACSACYWAQALVLGVDLN------MPRELEP
*: .*.:* . : . *. * * : * . :
MUL_3298|M.ulcerans_Agy99 SLARARMELSLAAQGRASPVDQGLVAALQARFPTD-DPDDAEALRAG-LG
MMAR_2051|M.marinum_M SLARARMELSLAAQGRASPVDQGLVAALQARFPTD-DPDDAEALRAG-LG
Mflv_3331|M.gilvum_PYR-GCK SLARARTELGLAAAGRASPLERGLIDALSARFLTA-DPDDTDALTAG-HR
Mvan_3057|M.vanbaalenii_PYR-1 SVARAKMELGLAAAGRASAVERGLIDALARRFTTD-DPADARTLQAG-HT
MSMEG_3574|M.smegmatis_MC2_155 SLTRARAELAAAASGRVSAVERDLIAALHKRFPTD-DPEDTEALLAG-HH
TH_2295|M.thermoresistible__bu ALARARRELDAAARGTASTVDRELIAALTLRFPTD-DPDDLDALAAG-RH
MAV_0683|M.avium_104 DRDAANNALRRAARQKPNGEDDKIIAALTGRYRDCPKTDDPRKCQAGRNQ
*. * ** . : :: ** *: .. * **
MUL_3298|M.ulcerans_Agy99 AYADAMAELAAAYP-ADVDVQALAADALLNVTAWALWDTATGEPAAGSRV
MMAR_2051|M.marinum_M AYADAMAALAAAYP-ADVDVQALAADALLNVTAWALWDTATGEPAAGSRV
Mflv_3331|M.gilvum_PYR-GCK AYADAMAALAQAYP-DDIDVVALAADALVNVTAWALWDSRTGDPAPGSRV
Mvan_3057|M.vanbaalenii_PYR-1 AYADAMSELARAYP-DDVDVAALAADALVNVTAWALWDSRTGEPAPGSRV
MSMEG_3574|M.smegmatis_MC2_155 AYADAMVAVARTYP-DDIDVQTLAADALVNVTAWALWDGRTGEPAPGSRV
TH_2295|M.thermoresistible__bu AYADAMATLARRHP-DDVDVQALAADALINVSAWALWDIDTGEPAPGSRV
MAV_0683|M.avium_104 AYYDGMKAVVDEFGRDDPNVITLFADAAMNMTPWAYWK--DGNPVS-PRT
** *.* :. . * :* :* *** :*::.** *. *:*.. .*.
MUL_3298|M.ulcerans_Agy99 LEAKRLLDQALATPAGRAHPGILHLYLHAMEMSATPEVALPAADLLRGLV
MMAR_2051|M.marinum_M LEAKRLLDQALATPAGRAHPGILHLYLHAMEMSATPEDALPAADLLRGLV
Mflv_3331|M.gilvum_PYR-GCK VEAMRLLDGALQTPAGRQHPGVLHLYLHAMEMSTTPQAALPAADLLRDLV
Mvan_3057|M.vanbaalenii_PYR-1 VEAKRILDDALATPAGRAHPGILHLYLHTMEMSTTPEAALPAADLLRGLV
MSMEG_3574|M.smegmatis_MC2_155 LEAKSILDRALTTPAGREHPGVLHLYIHTMEMSTTPQAALPAADRLRNLV
TH_2295|M.thermoresistible__bu LEAKEILESALATPEGRAHPGVLHLYLHTMEMSARPEDALWAADLLRDLV
MAV_0683|M.avium_104 TQAREYLEKALELSQYPPNEGPIHWYIHLMEQSRTPGAAGKYADRLAALA
:* *: ** . : * :* *:* ** * * * ** * *.
MUL_3298|M.ulcerans_Agy99 PDAGHLQHMPSHIDVLCGDYRSSVLANLAAVRADRRFVSREGPLN-----
MMAR_2051|M.marinum_M PDAGHLQHMPSHIDVLCGDYRSSVLANLAAVRADRRFVSREGPLN-----
Mflv_3331|M.gilvum_PYR-GCK PDAGHLRHMPSHIDVLCGNYRDSVVANLSAVEVDRRFVERQGSLN-----
Mvan_3057|M.vanbaalenii_PYR-1 PDAGHLRHMPSHIDVLCGNYRDSIVANLAAVQVDRHFVERQGPLN-----
MSMEG_3574|M.smegmatis_MC2_155 PDAGHLRHMPSHIDVLCGDYRSSVVSNLSAVEADRRFVEHRGPLN-----
TH_2295|M.thermoresistible__bu PDAGHLLHMPSHIDVLCGDYRSATLANLAAVQADRRFVDHAGPLN-----
MAV_0683|M.avium_104 PNSGHLVHMPSHIYYRMGDMPKAIRANKEAIDADERYFATEPHLYRPDGD
*::*** ****** *: .: :* *: .*.::. *
MUL_3298|M.ulcerans_Agy99 -FYSLYRAHDLHFIVYSAMFEGQS--QIALRAADELAGQLGAELLSIESP
MMAR_2051|M.marinum_M -FYSLYRAHDLHFIVYSAMFEGQS--QIALRAADELAGQLGAELLSIESP
Mflv_3331|M.gilvum_PYR-GCK -FYSLYRAHNLHFVVYSAMFEGNS--ATALQAADELATQLSPELLAIESP
Mvan_3057|M.vanbaalenii_PYR-1 -FYSLYRAHNLHFVVYSAMFEGNS--AIALRAADELSGQLTPELLAIESP
MSMEG_3574|M.smegmatis_MC2_155 -FYSLYRAHDLHFVVYSAMFEGQS--QIALSAADELAAQLTPDLLSVTSP
TH_2295|M.thermoresistible__bu -FSSLYRAHNLHFVVYAAMFEGRF--HTALRAADELAEQLTPELLSVESP
MAV_0683|M.avium_104 RYRYGYYLHNIHFVIAAAALSGDDDEHDVNRYADKLLQWLPDNASGFRAD
: * *::**:: :* :.* . **:* * : .. :
MUL_3298|M.ulcerans_Agy99 P-MADWLEAFVPLRTHVLVR-FGRWQELIAQPLPCDRDLYCTTTATIHYG
MMAR_2051|M.marinum_M P-MADWLEAFVPLRTHVLVR-FGRWQELIAQPLPCDRDLYCATTATIHYG
Mflv_3331|M.gilvum_PYR-GCK P-MADWLEAFVPLRVHVLVR-FGRWADLIATALPEDTALYCTTAATIHYG
Mvan_3057|M.vanbaalenii_PYR-1 P-MADWLEAFVPLRVHVLVR-FGRWDELIATPLPDDPQLYCTTTATIHYG
MSMEG_3574|M.smegmatis_MC2_155 P-MADWLEAFVPLRIHVLVR-FGRWDDLIAEPLPSDQALYCTTTATVHYG
TH_2295|M.thermoresistible__bu P-MADWLEAFVPLRTHVLVR-FGRWDDLIADPLPADRGLYCTTAATVHYG
MAV_0683|M.avium_104 VYRSAYYLAKINFSSTADIRGFDPPSPFNQQPLATIAYDFARLMADIWDK
: : * : : . :* *. : .*. :. * :
MUL_3298|M.ulcerans_Agy99 RGVALAATGQLAQAHAERVAFVEACARVP--ESRYLFNNTSRDILAVAAA
MMAR_2051|M.marinum_M RGVALAATGQLAQAHAERAAFVEACARVP--ESRYLFNNTSRDILAVAAA
Mflv_3331|M.gilvum_PYR-GCK RGVAHAASGNLDRARAERDLFAAAYDRIP--ESRYLFNNTSRDILAVAAT
Mvan_3057|M.vanbaalenii_PYR-1 RGVAHAASGHLDQAAAERELFAAAYDRIP--DSRYLFNNTSRDILAVAAA
MSMEG_3574|M.smegmatis_MC2_155 RGVAYAAMGDLSRADAERDAFIKAYDRIP--ETRYLFNNTSRDILAIAGA
TH_2295|M.thermoresistible__bu RGIAHAVKGQLQRAHAERAAFADAYARIP--PSRCLFNNTARDILAVADA
MAV_0683|M.avium_104 NNSPHWLDTLDGDVARYRQHATASGKQNADCDPRLELPKPELCLAAILRD
.. . . * : : . .* : :. : *:
MUL_3298|M.ulcerans_Agy99 MLDGEIAYRDGRFDEAFAHLRRAVTLDDTLPYDEPWGWMQPTRHAYGALL
MMAR_2051|M.marinum_M MLDGEIAYRDGRFEEAFAHLRRAVTLDDTLPYDEPWGWMQPTRHAYGALL
Mflv_3331|M.gilvum_PYR-GCK MLDGEIDYRAGDHDAAFAHLRRAVELDDAMPYDEPWGWMQPTRHALGALL
Mvan_3057|M.vanbaalenii_PYR-1 MLDGEIDYRAGRFDDAFAHLRRAVELDDTLPYDEPWGWMQPTRHALGALL
MSMEG_3574|M.smegmatis_MC2_155 MLDGEIAYRRGDHDVAFEHLRRAIALDDNLPYDEPWGWMQPTRHAYGALL
TH_2295|M.thermoresistible__bu MLDGEIAYREGRFEEAFTALRRAVNRYDNLPYDEPWGWMQPPRHALGALL
MAV_0683|M.avium_104 LGHARASAAKADWGAAADVANEAVDIQDKLPYDEPPLWPYPVRQTLASIL
: ... . * ..*: * :***** * * *:: .::*
MUL_3298|M.ulcerans_Agy99 LEQGHVEEAAAVYAADLGLDPTLARPCQHPGNVWSLHGYHECLQRLGRTA
MMAR_2051|M.marinum_M LEQGHVEEAAAVYAADLGLDPTLARPCQHPGNVWSLHGYHECLQRLGRTA
Mflv_3331|M.gilvum_PYR-GCK LEQGRVEEAAQVYAADLGLDPTLSRPCQHPGNVWSLHGYHECLTRLGRDA
Mvan_3057|M.vanbaalenii_PYR-1 LEQGRVEEAAQVYAADLGLDPTLSRSCQHPGNVWSLHGYHECLTRLGRGP
MSMEG_3574|M.smegmatis_MC2_155 LEQGRVEEAAQVYAADLGLDPTLSRACQHPNNVWSLHGYHECLRRLGRDA
TH_2295|M.thermoresistible__bu LEQGRVTEAAAVYAADLGLDSTLSRACRHPNNVWSLHGYHECLQRLGRTA
MAV_0683|M.avium_104 IRRAIAAGNPMERVLHLAAAKELLLKSLNEG-----KGDDPEQTPIGTYP
:.:. . . . .*. * . : . :* . :* .
MUL_3298|M.ulcerans_Agy99 EAAIIGQQLALAAARADVPIRASCACRVTA---CCDQ---------
MMAR_2051|M.marinum_M EAAIIGQQLALAAARADVPIRASCACRVTA---CCDQ---------
Mflv_3331|M.gilvum_PYR-GCK EAVIIGKQLELAAARADVPIEASCACRLQS--PCCD----------
Mvan_3057|M.vanbaalenii_PYR-1 EALIIGKQLELAAARADVPIEASCACRLQP--HCCD----------
MSMEG_3574|M.smegmatis_MC2_155 EAAIIGKQLELALARTDVPINASCACRLEVADPCCGN---------
TH_2295|M.thermoresistible__bu EAAIIDQQLRVALARADTPVQASCACRLQTADSCCGSAPMDPASAR
MAV_0683|M.avium_104 GNGWAYYGLLEIATRDGSPPEVVKAADAELARHWFGGTGYRNLDRL
* :* . * .. *. .