For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SVHRSPKPSPIVVMGVCGAGKSTVGAALAQRLGVPFTEADTLHSQANVTKMAAGKPLDDDDRRPWLRRVG RWLADHPGGGVISCSALARRYRDALRENCPQVEFLHLSGSAELIGRRLAARSDHFMPATLLRSQLDTLEP FGDDERGVTVDIDGVGGDVDSIVEAFLASG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2259 | - | - | 100% (171) | gluconate kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0502 | - | 2e-56 | 63.12% (160) | carbohydrate kinase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3635c | - | 4e-44 | 55.41% (148) | putative gluconokinase |
| M. marinum M | MMAR_3018 | - | 2e-91 | 94.74% (171) | gluconate kinase |
| M. avium 104 | MAV_2468 | aroK | 3e-57 | 67.92% (159) | shikimate kinase |
| M. smegmatis MC2 155 | MSMEG_0453 | aroK | 3e-56 | 62.11% (161) | shikimate kinase |
| M. thermoresistible (build 8) | TH_0740 | aroK | 1e-50 | 62.34% (154) | shikimate kinase |
| M. vanbaalenii PYR-1 | Mvan_5911 | - | 2e-56 | 64.38% (160) | carbohydrate kinase |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2259|M.ulcerans_Agy99 --MSVHRSPKPSPIVVMGVCGAGKSTVGAALAQRLGVPFTEADTLHSQAN
MMAR_3018|M.marinum_M --MSVHPSPKPSPIVVMGVCGAGKTTVAAALSQRLGVPFMEADTLHPQAN
MAV_2468|M.avium_104 --MSGS-----APVVVMGVSGSGKSTVGVTLARRLRVPFVDADTLHPPAN
Mflv_0502|M.gilvum_PYR-GCK --MAIP-------IVVMGVSGSGKSTVGAALAQRLRVPFADADDFHPPAN
Mvan_5911|M.vanbaalenii_PYR-1 --MAIP-------IVVMGVSGSGKSTVGAALAQRLRVPFADADDFHPPAN
MSMEG_0453|M.smegmatis_MC2_155 --MATP-------IVVMGVSGSGKSTVGAALAQRLRVPFADADDFHPPAN
TH_0740|M.thermoresistible__bu VVVDVPG------IVVMGVSGCGKSTVGAALARRLGVPFADADDFHPPAN
MAB_3635c|M.abscessus_ATCC_199 --MAQAS---PPVVVVMGVAGAGKTTVARLLAQRLDAPYAEGDDFHPEAN
: :*****.*.**:**. *::** .*: :.* :*. **
MUL_2259|M.ulcerans_Agy99 VTKMAAGKPLDDDDRRPWLRRVGRWLADH---PGGGVISCSALARRYRDA
MMAR_3018|M.marinum_M VTKMAAGKPLDDDDRRPWLRRVGRWLADH---PGGGVISCSALARRYRDT
MAV_2468|M.avium_104 IAKMAAGTPLGDDDRRPWLDEVGEWLAAH---RDGGVAACSALKRAYRDR
Mflv_0502|M.gilvum_PYR-GCK IAKMSAGHPLDDEDRYPWLESIGEWLADH---PDGGVMSCSALKRVYRDQ
Mvan_5911|M.vanbaalenii_PYR-1 IAKMSAGHPLDDEDRYPWLESIGEWLARH---PQGGVMSCSALKRSYRDQ
MSMEG_0453|M.smegmatis_MC2_155 IEKMSAGHALDDDDRYPWLEAIGKWLAEH---PAGGVMSCSALKRTYRDQ
TH_0740|M.thermoresistible__bu IAKMASGRPLDDPDRLPWLEAVGRWSAGQ---PGGAVVACSALRRGYRDR
MAB_3635c|M.abscessus_ATCC_199 IAKMAAGIPLDDTDREPWLRRIAEWICEHGRAGTGGVVTCSALKRHYRDI
: **::* .*.* ** *** :..* . : *.* :**** * ***
MUL_2259|M.ulcerans_Agy99 LRENCPQVEFLHLSGSAELIGRRLAARSDHFMPATLLRSQLDTLEPFGDD
MMAR_3018|M.marinum_M LRENCPQVAFLHLSGSAELIGRRLAARSDHFMPATLLRSQLDTLEPLGDD
MAV_2468|M.avium_104 LRAHCPDVAFLHLSGSAALLGPRLAARSGHFMPAALLQSQLDALEPLGPD
Mflv_0502|M.gilvum_PYR-GCK LRRHCPDIEFLHLAGAVETISRRQASRPGHFMPAKLLQSQFQTLEPLEPD
Mvan_5911|M.vanbaalenii_PYR-1 LRRHCPDIEFLHLEGSVETIGRRQASRPGHFMPAALLESQFETLEPLEPG
MSMEG_0453|M.smegmatis_MC2_155 LRQHCPDIEFLHLEGSMETIGRRQASRPGHFMPASLLESQFKTLEPLAPD
TH_0740|M.thermoresistible__bu LRRHRGDLVFLHLTGEPEVIARRQAGRTGHFMPSSLLRSQFDTLEPLQPD
MAB_3635c|M.abscessus_ATCC_199 LRTGWSDVFFLHLSGNRSLVGDRMSHRAGHFMPTSLLDSQFDILEPLQSD
** :: **** * :. * : *..****: ** **:. ***: .
MUL_2259|M.ulcerans_Agy99 ERGVTVDIDGVGGDVDSIVEAFLASG---------
MMAR_3018|M.marinum_M ERGVTVDIDGVGGDVDSIVEAFLASG---------
MAV_2468|M.avium_104 EAGLTVD---AGREVDSIVDVVLRARR--------
Mflv_0502|M.gilvum_PYR-GCK ERGVVID---VDQSIDGIIENYISSTHSPTAEEDR
Mvan_5911|M.vanbaalenii_PYR-1 ERGVTVD---VDQSIDGIVENYISTTDSLTAEED-
MSMEG_0453|M.smegmatis_MC2_155 ECGVAID---VDQSIDDIIESYVSATQSHTPEEDR
TH_0740|M.thermoresistible__bu EPGATVD---VDRSVDAIVDDCLDHVRSRRP----
MAB_3635c|M.abscessus_ATCC_199 EKGVALD---VGTEPEQLVAEALRQFGV-------
* * .:* .. . : :: :