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LVRCRHRQGIAAALVPGRGIAGVRGSAGGRAAAVIGSAHHEAVARVDELVLAIGPKLGAPSINRRDVVLV TGPWLAGTSSVITALRRRLPQHRFVESPRLGAGAVPTVVVFVVSAATPMTESDCALLDAAAGHTDVVIAA VTKIDLHRTWREVLAANRAKLAAHAPRYGAVPWVGVAAAPQLGPPGVDDLVATVRTELAAPDIARRNRLR AWHAGLLLAGQRFNRDAAGAGRRARVDGLREERGSVLQRRRQDRTGRTIALRGQIQQARVQLCYFARSRC ASVRTELQEDIAGLARQRLADFQSYARGRIDEIVTEVGDGITAQLVEVSREMSLPVDFPPADPLPAVAMP APPLASRRLETRLMMVLGVGFGLGVALTLSRLLAGLAPGLDLGLTLAGILGCVVVGLAVALWVVRTRALL ADRAVLERWTADVLSSLGCTLEQLVASRVLAAETLLATALWGSDEAANARAAAQVSAIDSELREHARAAA RAAARRDREMPTIRAALEAVCAELGESGTSSGTATPGTATAGGGAGLPRHSEANGRDFGS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1100 | - | - | 100% (550) | hypothetical protein MUL_1100 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0216 | - | 1e-158 | 61.12% (481) | hypothetical protein Mb0216 |
| M. gilvum PYR-GCK | Mflv_0452 | - | 2e-71 | 40.82% (414) | hypothetical protein Mflv_0452 |
| M. tuberculosis H37Rv | Rv0210 | - | 1e-157 | 61.04% (480) | hypothetical protein Rv0210 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4504c | - | 1e-100 | 44.42% (484) | hypothetical protein MAB_4504c |
| M. marinum M | MMAR_0450 | - | 0.0 | 98.84% (517) | hypothetical protein MMAR_0450 |
| M. avium 104 | MAV_4964 | - | 1e-155 | 57.17% (502) | hypothetical protein MAV_4964 |
| M. smegmatis MC2 155 | MSMEG_0254 | - | 1e-138 | 54.77% (482) | hypothetical protein MSMEG_0254 |
| M. thermoresistible (build 8) | TH_0164 | - | 1e-134 | 52.53% (495) | conserved hypothetical protein |
| M. vanbaalenii PYR-1 | Mvan_0200 | - | 4e-86 | 43.51% (439) | hypothetical protein Mvan_0200 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1100|M.ulcerans_Agy99 MVRCRHRQGIAAALVPGRGIAGVRGSAGGRAAAVIGSAHHEAVARVDELV
MMAR_0450|M.marinum_M ---------------------------------MIGSAHHEAVARVDELV
Mb0216|M.bovis_AF2122/97 ---------------------------------MIRAASDDPAG-VDELV
Rv0210|M.tuberculosis_H37Rv ---------------------------------MIRAASDDPAG-VDELV
MAV_4964|M.avium_104 -----------------------------------MSGDNPAAA-VDALV
MSMEG_0254|M.smegmatis_MC2_155 ------------------------------MSTATEEPTPDPIAEADALV
TH_0164|M.thermoresistible__bu --------------------------------------MTDPIAAADAVV
MAB_4504c|M.abscessus_ATCC_199 -------------------------------------MSTPADKQVDQLV
Mflv_0452|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0200|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_1100|M.ulcerans_Agy99 LAIGP---KLGAPSINRRDVVLVTGPWLAGTSSVITALRRRLPQHRFVES
MMAR_0450|M.marinum_M LAIGP---KLGAPSINRRDVVLVTGPWLAGTSSVITALRRRLPQHRFVES
Mb0216|M.bovis_AF2122/97 AAIAPGLAGLGLPVINRREVVLVTGPWLAGVSGVRAALAERLPQRRFVET
Rv0210|M.tuberculosis_H37Rv AAIAPGLAGLGLPVINRREVVLVTGPWLAGVSGVRAALAERLPQRRFVET
MAV_4964|M.avium_104 AAVSP---GLDPPAVHRSDAVLVTGPWMAGVTAVAAALQERLPQHKFVES
MSMEG_0254|M.smegmatis_MC2_155 AAVDP---GLSSPGVQARDVILVTGPWLAGTSSVLAALRERMPQHTFVES
TH_0164|M.thermoresistible__bu AAVEP---GLQPPGVQIRDAVLVTGPWLAGTTSVLTALQERLPDHTFVEA
MAB_4504c|M.abscessus_ATCC_199 LAVDP---ALGPLGVEPQDAVMVTGSWLAGASTLATGLKSRMPGTRIVEP
Mflv_0452|M.gilvum_PYR-GCK --------------MTG--------PPRAGVSTVAAGLRQRMPAVRVLDG
Mvan_0200|M.vanbaalenii_PYR-1 --------------MTGPETVLVAGPPRAGVSGVVAELRRRMPSHRFVEA
: . **.: : : * *:* .::
MUL_1100|M.ulcerans_Agy99 PRLGAGAVPTVVVFVVSAATPMTESDCALLDAAAGHTDVVIAAVTKIDLH
MMAR_0450|M.marinum_M PWLGAGAVPTAVVFVVSAATPMTESDCALLDAAAGHTDVVIAAVTKIDLH
Mb0216|M.bovis_AF2122/97 AELGPGDAPVAVVFVVSAATALTESDCVLLDTAAEHTDAVVAVVSKIDVH
Rv0210|M.tuberculosis_H37Rv AELGPGDAPVAVVFVVSAATALTESDCVLLDTAAEHTDAVVAVVSKIDVH
MAV_4964|M.avium_104 TDLGPGEVPTAVVFVVSAAAHLTPSDCALLDAATEHTDAVVGVVSKIDVH
MSMEG_0254|M.smegmatis_MC2_155 EDLLAGEAPKAVVFVVSAAAPITESDCALLDLASQYTDVVVGAVSKIDAH
TH_0164|M.thermoresistible__bu EALSAAEAPSAVLFVVSAAAPITESDCALLELAAHYTDLVIGVVSKIDAH
MAB_4504c|M.abscessus_ATCC_199 EDLRHGQSPAAVVFVCSGTAPLTPSDCGLIQLAAANTDALIAVVSKIDVH
Mflv_0452|M.gilvum_PYR-GCK AEAGTT--PVAVVFVVSAVAPLTESDCVLADAAAVDAEVVVAVVSKIDDH
Mvan_0200|M.vanbaalenii_PYR-1 GETGAPQRPAVVVFVVSAVAPITRSDCVLADRVAASTDAVVAVLAKIDDH
* .*:** *..: :* *** * : .: :: ::..::*** *
MUL_1100|M.ulcerans_Agy99 RTWREVLAANRAKLAAHAPRYGAVPWVGVAAAPQLGPPGVDDLVATVRTE
MMAR_0450|M.marinum_M RTWREVLAANRAKLAAHAPRYGAVPWVGVAAAPQLGPPGVDDLVATVRTE
Mb0216|M.bovis_AF2122/97 RGWRDVLTSNRDRLAARASRYARVPWVGAAAAPELGEPYLDDLVAAIQKQ
Rv0210|M.tuberculosis_H37Rv RGWRDVLTSNRDRLAARASRYARVPWVGAAAAPELGEPYLDDLVAAIQKQ
MAV_4964|M.avium_104 RGWREVLAANRDTLAAHAPRYARVPWVGAAALPDVGEPDVDDLAKTVAAQ
MSMEG_0254|M.smegmatis_MC2_155 RNWRDVRETDVKTCAARSQRYEQMPWAGVAAAPDLGEPRIGELVAALTER
TH_0164|M.thermoresistible__bu QDWREVLETNRATVAGRSPRFARMAWVGVAAAPDLGEPILDDLVELLSER
MAB_4504c|M.abscessus_ATCC_199 QSWREVMERNREILAQHDSRFRDITWLGVSTRG--AAPGLDELASAVRKI
Mflv_0452|M.gilvum_PYR-GCK RGWREVLEAGRAVADRSSGRLAGVPWLGVAAAPRLGEPRLDDLVDVLGRA
Mvan_0200|M.vanbaalenii_PYR-1 RDWTAVLEANRECLAGHAGRFGRVPWVGAAAAPRLGEPRMDELVALLRAQ
: * * . * :.* *.:: . * :.:*. :
MUL_1100|M.ulcerans_Agy99 LAAPDIARRNRLRAWHAGLLLAGQRFNRDAAGAGRRARVDGLREERGSVL
MMAR_0450|M.marinum_M LAAPDIARRNRLRAWQAGLLLAGQRFNRDAAGAGRRARVDGLREERGSVL
Mb0216|M.bovis_AF2122/97 LADPAVARRNMLRAWESRLLMVARRFDGDAQSAGRRARVDALRQQRRTVL
Rv0210|M.tuberculosis_H37Rv LADPAVARRNMLRAWESRLLMVARRFDGDAQSAGRRARVDALRQQRRTVL
MAV_4964|M.avium_104 LDDADLARRNRLRAWESRLRTVARRFDREVEAPGRRARVEALREERSTAL
MSMEG_0254|M.smegmatis_MC2_155 LTDTDMLRRNRLRAWEARLEAVMGRYEADASGADRKTRLETLRERRAEIN
TH_0164|M.thermoresistible__bu LADPDVQRRNRLRAWEARLGAVIARHEADAAGEDRRARVQALHARRDEIL
MAB_4504c|M.abscessus_ATCC_199 RGKPDLAERNRLRAWVTRLQGMLN----VPPEAGEGARADELRNQRQAAV
Mflv_0452|M.gilvum_PYR-GCK LADPSQRARNSLRAKQF--------------------RVSRLQDERDGLV
Mvan_0200|M.vanbaalenii_PYR-1 LDDPTRPARNALRALES--------------------RECLLRGTRDRLV
. ** *** * *: *
MUL_1100|M.ulcerans_Agy99 QRRRQDRTGRTIALRGQIQQARVQLCYFARSRCASVRTELQEDIAGLA--
MMAR_0450|M.marinum_M QRRRQDRTGRTIALRGQIQQARVQLCYFARSRCASVRTELQEDIAGLA--
Mb0216|M.bovis_AF2122/97 RQGRQSKSEHTIALRAQIQHARVKLSYFARNRCSLLRVELQEHVAGLS--
Rv0210|M.tuberculosis_H37Rv RQGRQSKSEHTIALRAQIQHARVKLSYFARNRCSLLRVELQEHVAGLS--
MAV_4964|M.avium_104 QQRRQAKTERSITLRGQIQQARVALSHSARNRCASVRTELQEHAAGLS--
MSMEG_0254|M.smegmatis_MC2_155 RTRRLTKTERSVALRSQLQQARVQLGYFARNRCNSVRTELQEDVAALG--
TH_0164|M.thermoresistible__bu RERRMAKSERTIALRSQLQQARVQLAYFARNRCTSVRAEWQEDVAEFNHL
MAB_4504c|M.abscessus_ATCC_199 RRTRSSKSERTLALRNRIAQARMTLLYFARKRVGSVGGELREDIAELK--
Mflv_0452|M.gilvum_PYR-GCK ALRRRTRLDAAGRLSRDLRQLRVTLSHDVRRRCAGLRADLLHRAGAVG--
Mvan_0200|M.vanbaalenii_PYR-1 QRRRREASERATALRSAIQQSRLTLTHTARRRCAELRTDLLAEATAVG--
* : * : : *: * : .* * : : .
MUL_1100|M.ulcerans_Agy99 ------RQRLADFQSYARGRIDEIVTEVGDGITAQLVEVSREMSLPVDFP
MMAR_0450|M.marinum_M ------RRRLADFQSYARGRIDEIVTEVGDGITAQLVGVSREMSLPVDFP
Mb0216|M.bovis_AF2122/97 ------RKDIARFAAYTRGRVQEVVAEVGEGAVAHLADVAQLLGVPVQPP
Rv0210|M.tuberculosis_H37Rv ------RKDIARFAAYTRGRVQEVVAEVGEGAVAHLADVAQLLGVPVQPP
MAV_4964|M.avium_104 ------RGKLSGFEAHTRDRLAEVVAEVSDGTDTQLADTAQAVGVAVDLP
MSMEG_0254|M.smegmatis_MC2_155 ------RRRIGEFETYVRERCDTIVDEVHEGVTVHLGDVASELGLDAPAT
TH_0164|M.thermoresistible__bu PWPSARRRRLIEFEFYVRSRAGEVVNEVDDGITTHLRDMARELDLPAPAE
MAB_4504c|M.abscessus_ATCC_199 ------RRDVAGFGDRVRRRVADIVAEVEQGTEEHLAEISAEVTQHWVAP
Mflv_0452|M.gilvum_PYR-GCK ------RRDVAGFPQHAWERCTEVLTGIEQDITEVTGADVGCGDVPVNLP
Mvan_0200|M.vanbaalenii_PYR-1 ------RGEVCRFAHRARRRSAEVLAAVEADLTAYTHDAPPRVTAPLLLP
* : * . * :: : .
MUL_1100|M.ulcerans_Agy99 PADPLPAVA--MPAPPLASRRLETRLMMVLGVGFGLGVALTLSRLLAGLA
MMAR_0450|M.marinum_M PADPLPAVA--MPAPPLASRRLETRLMMVLGVGFGLGVALTLSRLLAGLA
Mb0216|M.bovis_AF2122/97 VLENLPAVLPTVVAPPLTSRRLEIRLTTLLGAGFGLGIALTLSRLVAG--
Rv0210|M.tuberculosis_H37Rv VLENLPAVLPTVVAPPLTSRRLEIRLTTLLGAGFGLGIALTLSRLVAG--
MAV_4964|M.avium_104 ALEQLPAVE--VSPPPLKSRRQETWLMILLGVGFGLGVALTLSRLMSGLA
MSMEG_0254|M.smegmatis_MC2_155 PER--PSVP-DIASPPLKTRTLETRLMAVLAVGFGLGVALAVSRLLAG--
TH_0164|M.thermoresistible__bu AGE--PAGP-ELPGPPLRSRQLENRLMMLLGAGFGVGVAAAASRLFSG--
MAB_4504c|M.abscessus_ATCC_199 RPSANRPVPPEAGDPPVRSRRLETRMMALFGIFFGLGAALTVSRLVAY--
Mflv_0452|M.gilvum_PYR-GCK PDP--------PPHPPPRSWRLERQLTAVLGAGFGLGVAMVVTRLVAG--
Mvan_0200|M.vanbaalenii_PYR-1 -------------DPPLRARRLETRLMTVLGAGFGLGVAVVVTRFLAG--
** : * : ::. **:* * . :*:.:
MUL_1100|M.ulcerans_Agy99 PGLDLGLTLAGILGCVVVGLAVALWVVRTRALLADRAVLERWTADVLSSL
MMAR_0450|M.marinum_M PGLDLGLTLAGILGCVVVGLAVALWVVRTRALLADRAVLERWTADVLLSL
Mb0216|M.bovis_AF2122/97 --LTPGLAASGMVAGVAIGLAVTAWVVNARALLHDRVVVDRWTGEVTASL
Rv0210|M.tuberculosis_H37Rv --LTPGLAASGMVAGVAIGLAVTAWVVNARALLHDRVVVDRWTGEVTASL
MAV_4964|M.avium_104 SRLSPALAVAAAVVCVLISVALTFLVINIRGLLRDRALLDRWAGDATASL
MSMEG_0254|M.smegmatis_MC2_155 --AAPRLAVTGLAVGALVGLLLAVWVVSTRGLLHDRAVLDRWVNDATATV
TH_0164|M.thermoresistible__bu --LSPTLTAAGMVVGGLVALAVTVWMVGLRNVLQERAVLDRWVGEVAAAL
MAB_4504c|M.abscessus_ATCC_199 --ARPGLAPVGLAVGLVAGAVIAVWLVAVRGLLHDRTVLDRWLGDTMGEL
Mflv_0452|M.gilvum_PYR-GCK --LAPGLTAAGLAVGGVLGFLTTAWVVRARALLHDRAVLQAWAADAVAAV
Mvan_0200|M.vanbaalenii_PYR-1 --LAPEFATAALTAGAAIGLVTTAWVIRARALLHDRAVLERWAADGVAAL
:: . . : :: * :* :*.::: * : :
MUL_1100|M.ulcerans_Agy99 GCTLEQLVASRVLAAETLLATALWGSDEAANARAAAQVSAIDSELREHAR
MMAR_0450|M.marinum_M GCTLEQLVASRVLAAETLLATALWGSDEAANARAAAQVSAIDSELREHAR
Mb0216|M.bovis_AF2122/97 RSVVEQLVATRVVAVETLLSTAISERDDAENARVADQVSIIDGELREHAV
Rv0210|M.tuberculosis_H37Rv RSVVEQLVATRVVAVETLLSTAISERDDAENARVADQVSIIDGELREHAV
MAV_4964|M.avium_104 RSVVEELVATRVLVAESVLSKALLAQDEAENAAVSASVSAIDTELREHAL
MSMEG_0254|M.smegmatis_MC2_155 RSAVEELVATRVLQAEADLTTQLAGRDEAEAAAAAEQIAAIDTELREHAV
TH_0164|M.thermoresistible__bu RSTVEELVATRVLAAERELTAELANREEEEGAAAAAQIAEIDAELREHAT
MAB_4504c|M.abscessus_ATCC_199 RAYLEQWVAARVLEVETRLNADLVEIDERENDKLAARVGQIDSELREAAM
Mflv_0452|M.gilvum_PYR-GCK RAAADERVGTGTLAVEAGRAGAGARSDE--DAALGRRIASLDAEIQRLSQ
Mvan_0200|M.vanbaalenii_PYR-1 RAAVEERVAAGMLAAETAIAAESARAAAARDGDTRRRIAAIEAELHDLSQ
. :: *.: : .* :. :: *:: :
MUL_1100|M.ulcerans_Agy99 AAARAAARRDREMPTIRAALEAVCAELGESGTSSGTATPGTATAGGGAGL
MMAR_0450|M.marinum_M AAARAAARRDREMPTIRAALEAVCAELGESGTSSGTATPGTATAGGGAGL
Mb0216|M.bovis_AF2122/97 AAARAAALRDREMPAVRAALEAVRAELGEPGTPTTGLF------------
Rv0210|M.tuberculosis_H37Rv AAARAAALRDREMPAVRAALEAVRAELGEPGAPTTGLF------------
MAV_4964|M.avium_104 AAARAAAARDREMPAVTAALEAVRAELGEPGIQPGGSPAEDAGGEKTEKP
MSMEG_0254|M.smegmatis_MC2_155 ATARAAALRDRRIPPLRRALDAVRADLYG------------------DSA
TH_0164|M.thermoresistible__bu ARARAAAIRDSRVPILQAALDAVRAELYGPDGSEPETEEPEETGEPGEAA
MAB_4504c|M.abscessus_ATCC_199 NTARATALRNRDLPSVHKALTKVTERLDAIAASDENMTS-----------
Mflv_0452|M.gilvum_PYR-GCK R-----SPDGPVLPVGRPAGGGHLNRSCE---------------------
Mvan_0200|M.vanbaalenii_PYR-1 ARM-LLVRRENLLPVGRPPGGGHLNRSCE---------------------
:* .
MUL_1100|M.ulcerans_Agy99 PRHSEANGRDFGS-------------------------------------
MMAR_0450|M.marinum_M PRHSEANGRDFGS-------------------------------------
Mb0216|M.bovis_AF2122/97 --------------------------------------------------
Rv0210|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4964|M.avium_104 ASRSEDGDRP----------------------------------------
MSMEG_0254|M.smegmatis_MC2_155 STDE----------------------------------------------
TH_0164|M.thermoresistible__bu EVDETDGPAEVDETGVTEGVTEEGTEGVTEVTDAGTGDGEAEPPAEPDIA
MAB_4504c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0452|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0200|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_1100|M.ulcerans_Agy99 ---------------
MMAR_0450|M.marinum_M ---------------
Mb0216|M.bovis_AF2122/97 ---------------
Rv0210|M.tuberculosis_H37Rv ---------------
MAV_4964|M.avium_104 ---------------
MSMEG_0254|M.smegmatis_MC2_155 ---------------
TH_0164|M.thermoresistible__bu EPDAEERENGPQTQV
MAB_4504c|M.abscessus_ATCC_199 ---------------
Mflv_0452|M.gilvum_PYR-GCK ---------------
Mvan_0200|M.vanbaalenii_PYR-1 ---------------