For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSVRRLAALLASTLMVMGLVLAGPASADVDQCAPPGIDSASALPTNLAAAAAGPDADRYTTPTVKPLQDI RVDQLGLSTPGVLTVGTLSDAPPSICIDSAGQFTGFDNELLRAVADKLGLRVDFVGTEFSGLLAQTASRR FDVASSSITTTDARRRTVGFTNGYDFGYFSLVVPTGSPITGFDQLGPGQRIGVVQGTVQESYVIDTLHLE PVKYPDYNTVYASLKTRQIDAWVAPSQQASGTVQPGDPAQIIENTFSLDNFVAWAVAKENQPLIDALNSG LDAIIADGTWARLYTDWVPRALPPGWKPGSKAAPEPQLPDFNAIAAAREEPEDTGPVGPKSVLSQLADSF LDWDLYKQAIPDLLKTGLPNTLILTVSAGIIGLVLGMGLAMAGISRAVWLRWPARIYTDIFRGLPEVVII LLIGLGVGPIVGHLTGNNPYPLGIAALGLMAAAYIGEIFRSGIQSVEAGQLEAARALGFSYRSSMRLVVV PQGVRRVLPALMNQFISLLKASSLVYFLGLIANQRELFQVGRDLNAQTGNLSPLVAAGLFYLMLTIPLTH LVNYIDNRLRRGRPATEEDPVPPAATQEMI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6909 | - | - | 100% (590) | amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family protein |
| M. smegmatis MC2 155 | MSMEG_5318 | - | 4e-36 | 27.41% (478) | glutamine ABC transporter, permease/substrate-binding protein |
| M. smegmatis MC2 155 | MSMEG_6307 | - | 2e-34 | 26.55% (516) | glutamine-binding periplasmic protein/glutamine transport |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0419c | glnH | 4e-09 | 26.05% (215) | glutamine-binding lipoprotein |
| M. gilvum PYR-GCK | Mflv_0858 | - | 0.0 | 82.90% (579) | polar amino acid ABC transporter, inner membrane subunit |
| M. tuberculosis H37Rv | Rv0411c | glnH | 4e-09 | 26.05% (215) | glutamine-binding lipoprotein |
| M. leprae Br4923 | MLBr_00303 | glnH | 6e-08 | 24.77% (218) | putative glutamine-binding protein |
| M. abscessus ATCC 19977 | MAB_0277c | - | 9e-33 | 25.80% (500) | amino acid ABC transporter permease |
| M. marinum M | MMAR_0061 | glnQ | 0.0 | 72.79% (577) | ABC transporter permease protein GlnQ |
| M. avium 104 | MAV_0059 | - | 0.0 | 72.68% (582) | amino acid ABC transporter, permease protein, |
| M. thermoresistible (build 8) | TH_0515 | - | 0.0 | 79.49% (590) | amino acid ABC transporter, permease protein, 3-TM region, |
| M. ulcerans Agy99 | MUL_2809 | glnH | 8e-08 | 26.05% (215) | glutamine-binding lipoprotein GlnH |
| M. vanbaalenii PYR-1 | Mvan_6047 | - | 0.0 | 84.20% (576) | polar amino acid ABC transporter, inner membrane subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0858|M.gilvum_PYR-GCK -MSCTRVLRPTVKTFALALIIGMVTA----MGLAAPAGAQTDQCSPPGEQ
Mvan_6047|M.vanbaalenii_PYR-1 -MSCMRVLRPSVKSLVLALIIGMVAA----MGLAAPAGAQVDQCTPPGIE
MSMEG_6909|M.smegmatis_MC2_155 -MSVRRLA-------ALLASTLMVMG----LVLAGPASADVDQCAPPGID
TH_0515|M.thermoresistible__bu ---VTRAA--VVAVIALLVGSLTAGG----TVLAAPAAATVDQCAPPGVQ
MMAR_0061|M.marinum_M -------------MLAVSATILIVLG----LALAAPALADHNQCAPAGVD
MAV_0059|M.avium_104 ---MGRRGTRRGKLLALTATVLMVCGS--SALLAPPAAADRNQCAPAGPK
Mb0419c|M.bovis_AF2122/97 -MTRRALLARAAAPLAPLALAMVLASCGHSETLGVEATPTLPLPTPVGME
Rv0411c|M.tuberculosis_H37Rv -MTRRALLARAAAPLAPLALAMVLASCGHSETLGVEATPTLPLPTPVGME
MUL_2809|M.ulcerans_Agy99 -MRRLPGLRRAASALAVLALVITLDGCGHSEPLKVESTPTLPLPTPVGME
MLBr_00303|M.leprae_Br4923 MMTRQFKIQRACS---VLATAMMLAACGHAELLTVASMPTLPPPTPVGME
MAB_0277c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_0858|M.gilvum_PYR-GCK SASALPTNLAAAATGP-AADKYTTATVTPLDAVDVDALGLSEPGTLTVGT
Mvan_6047|M.vanbaalenii_PYR-1 SASALPTNLAAAAAGP-AADKYTTATVKPLASVDLNALGLTQPGTLTVGT
MSMEG_6909|M.smegmatis_MC2_155 SASALPTNLAAAAAGP-DADRYTTPTVKPLQDIRVDQLGLSTPGVLTVGT
TH_0515|M.thermoresistible__bu SASPLPTNLAAAEAGP-GVDRYTTDGVVPLDNIDPSALRLRVPGVLTVGT
MMAR_0061|M.marinum_M SAMVLPADLSSATTAGSDEDVQTTAGVVPLSSVNIGDLGLGTPGVLTAGT
MAV_0059|M.avium_104 SAAVLPENLTRGGSMS-QPDEHTTPTVEPLSSVRIDTLGLGTPGVLTVGT
Mb0419c|M.bovis_AF2122/97 IMPPQPP-LPPDSSSQDCDPTASLRPFATKAEADAAVADIRARGRLIVGL
Rv0411c|M.tuberculosis_H37Rv IMPPQPP-LPPDSSSQDCDPTASLRPFATKAEADAAVADIRARGRLIVGL
MUL_2809|M.ulcerans_Agy99 VMPPEPP-LPADSSSQDCDPTASLRPFPTKAEADAAVADIRARGRLIVGL
MLBr_00303|M.leprae_Br4923 QVPPELL-LPQDNTEEDCDPTASLRPFPTKAEADAAVAEIRARGRLIVGL
MAB_0277c|M.abscessus_ATCC_199 --------------------MFRAIVLALLALVAVAGCAAPTQEPLRVGT
. * .*
Mflv_0858|M.gilvum_PYR-GCK LSDAPPSICID-SSGQFTGFDNELLRAVADRLG---LRINFVGTEFSGLL
Mvan_6047|M.vanbaalenii_PYR-1 LSDAPPSICID-SAGQYTGFDNELLKAVAEKLG---LRVNFVGTEFSGLL
MSMEG_6909|M.smegmatis_MC2_155 LSDAPPSICID-SAGQFTGFDNELLRAVADKLG---LRVDFVGTEFSGLL
TH_0515|M.thermoresistible__bu LSDAPPSICIN-SLGEFTGFDNELLRAIAAKLG---LQISFVGTEFSALL
MMAR_0061|M.marinum_M LSDAPPNTCIN-STGQFTGFDNELLRAIAAKLG---LQVRFVGTDFSGLL
MAV_0059|M.avium_104 LSGAPPNVCIT-PTGQYSGFDNQLLRAIAGKLG---LQVRFVGTDFAGLL
Mb0419c|M.bovis_AF2122/97 DIGSNLFSFRDPITGEITGFDVDIAGEVARDIFGVPSHVEYRILSAAERV
Rv0411c|M.tuberculosis_H37Rv DIGSNLFSFRDPITGEITGFDVDIAGEVARDIFGVPSHVEYRILSAAERV
MUL_2809|M.ulcerans_Agy99 DIGSNLFSFRDPITGEITGFDVDIASEVARDIFGGPTHVEYRILSAAERI
MLBr_00303|M.leprae_Br4923 EIGSNLFSFRDPITGEITGFDIDIAGEVARDIFGTPSHMEYRILSTAARI
MAB_0277c|M.abscessus_ATCC_199 EGVYAPFSFHDGHTGELTGYDVDVARAVGEKLG---RPVEFVEIPWDAIF
*: :*:* :: :. : : : .
Mflv_0858|M.gilvum_PYR-GCK AQVASRRFDVGSSSITTTDARRQTVGFTNGYDFGYFSLVVPKG-SPITGF
Mvan_6047|M.vanbaalenii_PYR-1 AQVAARRFDVGSSSITTTDARRRTVGFTNGYDFGYFSLVVPKG-SAITGF
MSMEG_6909|M.smegmatis_MC2_155 AQTASRRFDVASSSITTTDARRRTVGFTNGYDFGYFSLVVPTG-SPITGF
TH_0515|M.thermoresistible__bu AQVASGRFDVGSSSITTTEQRRRTVEFTNGYDFGYFSLVVPSG-SAITGF
MMAR_0061|M.marinum_M AQVAARRFDVGSASVKLTEARRRTVAFTNGYDFGYYSLVVPPG-SAITKF
MAV_0059|M.avium_104 AQVASRRFDVGSSSIKATDERRQTVAFTNGYDFGYYALVVPPG-SAIKEF
Mb0419c|M.bovis_AF2122/97 TALQKSQVDIVVKTMSITCERRKLVNFSTVYLDANQRILAPRD-SPITKV
Rv0411c|M.tuberculosis_H37Rv TALQKSQVDIVVKTMSITCERRKLVNFSTVYLDANQRILAPRD-SPITKV
MUL_2809|M.ulcerans_Agy99 TALQSSQVDVVVKTMTITCERRKLVNFSTVYLDANQRILTSRD-SPIFKV
MLBr_00303|M.leprae_Br4923 TALQKSEVDIIVKTMTITCKRRKLVNFSTVYLDAKQRILAPRD-SPITKP
MAB_0277c|M.abscessus_ATCC_199 AGLDAERFDVVANQVTITPARKAKYDISTPYAVGEGVIVTRADDNSIHSL
: ..*: :. * *: ::. * . ::. . ..*
Mflv_0858|M.gilvum_PYR-GCK DELVAGQRIGVVQGTVQEAYVIDTLK-LQPVKFPDYNTVYASLKTGQIDA
Mvan_6047|M.vanbaalenii_PYR-1 EKLAPGQRIGVVQGTVQEAYVIDTLG-LQPVKFPDYNTVYASLKTGQIDA
MSMEG_6909|M.smegmatis_MC2_155 DQLGPGQRIGVVQGTVQESYVIDTLH-LEPVKYPDYNTVYASLKTRQIDA
TH_0515|M.thermoresistible__bu GDLVPGQRIGVVQGTVQESYVVDTLG-LRPVIFPDYNTVYASLKTRQIDA
MMAR_0061|M.marinum_M SDLAPGQRIGVVQGTVEESYVVNSLH-LQPVKYPDFATVYGNLKTHQIDA
MAV_0059|M.avium_104 TDLAAGQRIGVVQGTVEESYVVDTLH-LQPVKYPDFATVYASLKTRQIDA
Mb0419c|M.bovis_AF2122/97 SDLS-GKRVCVARGTTSLRRIREIAPPPVIVSVVNWADCLVALQQREIDA
Rv0411c|M.tuberculosis_H37Rv SDLS-GKRVCVARGTTSLRRIREIAPPPVIVSVVNWADCLVALQQREIDA
MUL_2809|M.ulcerans_Agy99 SDLS-GKRVCVARGTTSLRRIREIAPPPVIVSVVNWADCLVALQQREIDA
MLBr_00303|M.leprae_Br4923 SDLS-NKRVCMTRGTTSLHQVSEVVPPPIIVSAENWADCLVAMQQREIDA
MAB_0277c|M.abscessus_ATCC_199 SDVR--GKVAAENATSNWSQIARDAG-ARVEAVEGFTQSITLLSQGRVDV
.: :: ..* . : .: :. .:*.
Mflv_0858|M.gilvum_PYR-GCK WVSPSQQAQGTVQPA-DPVEIIENTFSLDNFIAWAVASDNQPLIDALNSG
Mvan_6047|M.vanbaalenii_PYR-1 WVAPSQQAQGTVQPG-DPADIIENTFSLDNFIAWAVAGDNQPLIDALNSG
MSMEG_6909|M.smegmatis_MC2_155 WVAPSQQASGTVQPG-DPAQIIENTFSLDNFVAWAVAKENQPLIDALNSG
TH_0515|M.thermoresistible__bu WVAPSQQAEGTVRPG-DPAEIIENTFSLDNFIAYAVAPGNQPLIDALNAG
MMAR_0061|M.marinum_M WVAPGNQAEAAIRPG-DPAVLVANTFGAGDFVAYVVARDNRPLLDALNSG
MAV_0059|M.avium_104 WVAPAGQAATTIQPG-DPAVVVANTISPGNFVAYAVAKDNKPLVDALNSG
Mb0419c|M.bovis_AF2122/97 VSTDDTILAGLVEE--DPYLHIVGPDMADQPYGVGINLDNTGLVRFVNGT
Rv0411c|M.tuberculosis_H37Rv VSTDDTILAGLVEE--DPYLHIVGPDMADQPYGVGINLDNTGLVRFVNGT
MUL_2809|M.ulcerans_Agy99 VSTDDTILAGLVEE--DPYLHIVGPNMANQPYGIGINLDNTGLVRFVNGT
MLBr_00303|M.leprae_Br4923 ISTDDAILAGLVEE--DPYLHIVGPNMATQPYGIGINLNNTTLVRFVNGT
MAB_0277c|M.abscessus_ATCC_199 VINDSIAVYAYLASTGDPAVKIAGATGQRSEQGFAARK-NSGLLPDLDKA
: ** : .. . . * *: ::
Mflv_0858|M.gilvum_PYR-GCK LDAVIADGTWSRLYSDWVPRALPPGWKPGSKTAPTPVLPDFTAIAAQNQD
Mvan_6047|M.vanbaalenii_PYR-1 LDAVIADGTWSRLYTDWVPRAVPPGWKPGSKAAPAPELPDFAAIAAQNQS
MSMEG_6909|M.smegmatis_MC2_155 LDAIIADGTWARLYTDWVPRALPPGWKPGSKAAPEPQLPDFNAIAAAREE
TH_0515|M.thermoresistible__bu LDAVIADGTWARLYSEWVPRALPPGWKPGSKAAPPPQLPDFDAIAAERAS
MMAR_0061|M.marinum_M LDAVIADGTWSQLYSKWVPRTLPPGWKPGSRAVAAPTLPDFAAIAAAHR-
MAV_0059|M.avium_104 LDAVIADGTWSNLYSQWVPRTLPPGWKPGSQAVAPPKLPDFAAIAASQH-
Mb0419c|M.bovis_AF2122/97 LERIRNDGTWNTLYRKWLTVLGP---------APAPPTPRYVD-------
Rv0411c|M.tuberculosis_H37Rv LERIRNDGTWNTLYRKWLTVLGP---------APAPPTPRYVD-------
MUL_2809|M.ulcerans_Agy99 LERIRNDGTWNTLYRKWLSVLGP---------APAPPRPRYVD-------
MLBr_00303|M.leprae_Br4923 LERIRRDGTWITLYRKWLTVLGP---------APAPPTPRYVD-------
MAB_0277c|M.abscessus_ATCC_199 LDQLAADGTLTRISQKYLKTDASG--------TTKPQAGKGDS-------
*: : *** : .:: . .. *
Mflv_0858|M.gilvum_PYR-GCK TGAPVAPAEPKSTLSQLAASFLDWDLYKQAIPDLFKTGLPNTLILTICAS
Mvan_6047|M.vanbaalenii_PYR-1 AQGPTAPVQPKSTLSQLAASFLDWDLYKQAIPDLFKTGLPNTLILTVAAS
MSMEG_6909|M.smegmatis_MC2_155 PED-TGPVGPKSVLSQLADSFLDWDLYKQAIPDLLKTGLPNTLILTVSAG
TH_0515|M.thermoresistible__bu QQPAAGPGVRKSTLAQLADSFLDWELYRQAIPDLLTTGLPNTLLLTVGAG
MMAR_0061|M.marinum_M -HKPVGPAAPKSALTQLRDSFFDWDMYRQAIPTLFKTGLPNTLILTLSAS
MAV_0059|M.avium_104 -HKAVGPAAPKSTLAQLRDSFFDWDMYRQAIPTLLRTGLPNTLILTFSAS
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 -----------------GSTRSDTQLVLDNLWPMARAMITVTLPLTAISF
Mflv_0858|M.gilvum_PYR-GCK IIGLILGMALAIAGISKSRWLRWPARVYTDIFRGLPEVVIILLIGLGVGP
Mvan_6047|M.vanbaalenii_PYR-1 IIGLILGMALAIAGISKSRWLRWPARIYTDIFRGLPEVVIILLIGLGVGP
MSMEG_6909|M.smegmatis_MC2_155 IIGLVLGMGLAMAGISRAVWLRWPARIYTDIFRGLPEVVIILLIGLGVGP
TH_0515|M.thermoresistible__bu VIGLVLGMVLAIAGISRSRLLRWPARVYTDIFRGLPEVVIILLIGLGLGP
MMAR_0061|M.marinum_M IIGLALGMALAIAGISHQRWLRWPARVYTDIFRGLPEVVIILIIGLGVGP
MAV_0059|M.avium_104 VIGLVLGMVLAVAGISHARWLRWPARVYTDVFRGLPEVVIILLIGLGIGP
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 VIGLVIALGVALARMSGHRVVTGLARIYISVIRGTPLLLQLFLIFFALPE
Mflv_0858|M.gilvum_PYR-GCK VVGHLTNNNPFPLGIAALGLMAAAYVGEIFRSGIQSVDPGQLEASRALGF
Mvan_6047|M.vanbaalenii_PYR-1 VVGHLTGNNPFPLGIAALGLMAAAYVGEIFRSGIQSVDPGQLEASRALGF
MSMEG_6909|M.smegmatis_MC2_155 IVGHLTGNNPYPLGIAALGLMAAAYIGEIFRSGIQSVEAGQLEAARALGF
TH_0515|M.thermoresistible__bu VVGGLTGYNPFPLGILALGLMAAAYVGEILRSGIQSVEPGQLEAARALGF
MMAR_0061|M.marinum_M IVGGLTNNNPYPLGIAALGLMAGAYVGEILRSGIQSVDPGQLEASRALGF
MAV_0059|M.avium_104 IVGGLTNNNPYPLGIAALGMMAAAYIGEILRSGIQSVDPGQLEASRALGF
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 FG---VKISPFPAAVIAFSLNVGGYAAEIIRSSILSIPRGQWEAASSLGM
Mflv_0858|M.gilvum_PYR-GCK SYSTSMRLVVVPQGVRRVLPALMNQFISLLKASSLVYFLGLIANQRELFQ
Mvan_6047|M.vanbaalenii_PYR-1 SYPTSMRLVVVPQGVRRVLPALMNQFISLLKASSLVYFLGLIANQRELFQ
MSMEG_6909|M.smegmatis_MC2_155 SYRSSMRLVVVPQGVRRVLPALMNQFISLLKASSLVYFLGLIANQRELFQ
TH_0515|M.thermoresistible__bu SYPAAMRLVVVPQGVRRVLPALMNQFISLLKASSLVYFLGLVADQRELFQ
MMAR_0061|M.marinum_M SYSAAMRLVVVPQGVRRVLPALVNQFIALLKASALVYFLGLIAQQRELFQ
MAV_0059|M.avium_104 SYATAMRLVVVPQGVRRVLPALVNQFIALLKASALVYFLGLVADQRELFQ
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 SYSTTLWRIVIPQASRVAVPPLSNTLISLVKDTSLASAILVTDVMR---T
Mflv_0858|M.gilvum_PYR-GCK VGRDLNAQTGNLSPLVAAGLFYLALTIPLTHLVNYIDVRLRRGRR-PDEK
Mvan_6047|M.vanbaalenii_PYR-1 VGRDLNAQTGNLSPLVAAGLFYLALTIPLTHLVNFIDTRLRRGRK-PDEK
MSMEG_6909|M.smegmatis_MC2_155 VGRDLNAQTGNLSPLVAAGLFYLMLTIPLTHLVNYIDNRLRRGRP-ATEE
TH_0515|M.thermoresistible__bu VGRDLNAQTGSLSPLVAAGLFYLALTIPLTHLVNYVDNRLRRGRK-PAAE
MMAR_0061|M.marinum_M VGRDLNAQTGNLSPLVAAGIFYLMLTVPLTHLVNYIDARLRRGRRRLDPE
MAV_0059|M.avium_104 VGRDLNAETGNLSPLVAAGACYLILTVPLTHLVNMIDARLRRGRAAVDPE
Mb0419c|M.bovis_AF2122/97 --------------------------------------------------
Rv0411c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2809|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00303|M.leprae_Br4923 --------------------------------------------------
MAB_0277c|M.abscessus_ATCC_199 AQVAAAPTFQFFTLYVTAGVYYWIVCMAMSAVQDRLEQRLEKSVAR----
Mflv_0858|M.gilvum_PYR-GCK DPLVLAT---SQEMN
Mvan_6047|M.vanbaalenii_PYR-1 DPLVLAT---SQEMN
MSMEG_6909|M.smegmatis_MC2_155 DPVPPAA---TQEMI
TH_0515|M.thermoresistible__bu DPLEPAT---AQEMI
MMAR_0061|M.marinum_M DPPGVVSSTIGEEMT
MAV_0059|M.avium_104 EPAEMLT--FGQEIT
Mb0419c|M.bovis_AF2122/97 ---------------
Rv0411c|M.tuberculosis_H37Rv ---------------
MUL_2809|M.ulcerans_Agy99 ---------------
MLBr_00303|M.leprae_Br4923 ---------------
MAB_0277c|M.abscessus_ATCC_199 ---------------