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MSEREAGGSFDYLWEELTPPPVPEQNGFDAFDDNTWDFKPAPVPWYRTRGAAVALTAAGIAAAAIVVSLV LLLLRDTSPVDDEQTTTVTPTTTATIAPSPSLRVGVPPAAPPPPPPTTQEEEAPRQAPVYRPPQRQREST KKPEIGVTRTPVTRSPISVAPQQRAPRN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6525 | - | - | 100% (168) | hypothetical protein MSMEG_6525 |
| M. smegmatis MC2 155 | MSMEG_4349 | - | 8e-09 | 29.58% (142) | hypothetical protein MSMEG_4349 |
| M. smegmatis MC2 155 | MSMEG_0700 | - | 8e-09 | 35.09% (114) | hypothetical protein MSMEG_0700 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2287c | - | 3e-07 | 29.32% (133) | hypothetical protein Mb2287c |
| M. gilvum PYR-GCK | Mflv_2951 | - | 2e-07 | 31.21% (173) | hypothetical protein Mflv_2951 |
| M. tuberculosis H37Rv | Rv2264c | - | 3e-07 | 29.32% (133) | hypothetical protein Rv2264c |
| M. leprae Br4923 | MLBr_00877 | mmpS3 | 3e-07 | 31.75% (126) | hypothetical protein MLBr_00877 |
| M. abscessus ATCC 19977 | MAB_4291 | - | 2e-07 | 31.20% (125) | hypothetical protein MAB_4291 |
| M. marinum M | MMAR_3358 | - | 2e-09 | 32.26% (124) | hypothetical protein MMAR_3358 |
| M. avium 104 | MAV_4816 | - | 6e-09 | 30.30% (132) | hypothetical protein MAV_4816 |
| M. thermoresistible (build 8) | TH_2748 | - | 2e-10 | 32.93% (167) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3555 | mmpS3 | 3e-07 | 27.70% (148) | membrane protein MmpS3 |
| M. vanbaalenii PYR-1 | Mvan_3562 | - | 2e-08 | 32.88% (146) | putative membrane protein MmpS3 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2287c|M.bovis_AF2122/97 MATGARPALGLSIGVTNLAAVAADHS---ITRKPVLTLYRQRPPEVGVPS
Rv2264c|M.tuberculosis_H37Rv MATGARPALGLSIGVTNLAAVAADHS---ITRKPVLTLYRQRPPEVGVPS
MMAR_3358|M.marinum_M MAEGARPALGLSIGATNLAAVTADSA---ILRKPVLTLYRQRPPEIGLPS
MAV_4816|M.avium_104 MRDMSEP-LGLSIGVANLVAARAGSVP--VIRSSVLTLFEQRPTEVGLPD
MAB_4291|M.abscessus_ATCC_1997 MAN----ALGLSIGATQLVATPDDPQSQPVVRSSILTLHEDGPPEVGVPS
TH_2748|M.thermoresistible__bu --------------------------------------------------
Mflv_2951|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3562|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_3555|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
MSMEG_6525|M.smegmatis_MC2_155 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 ENPRLDEPGLVITDFVDRVGDSVGIVAADGSVYRSEALVADALLALAYTA
Rv2264c|M.tuberculosis_H37Rv ENPRLDEPGLVITDFVDRVGDSVGIVAADGSVYRSEALVADALLALAYTA
MMAR_3358|M.marinum_M ENPRLDQSGLVISDFVDRVGDQIGIVAADGSVHRSEALVADALRALAYTA
MAV_4816|M.avium_104 ENPNLTEPGLVLRGFVERVGDRAPLVAADGTKYLGAALTVEAVEAMARAV
MAB_4291|M.abscessus_ATCC_1997 ------QPGLTLTGFVGRVGDPVGIVAADGSVHRAEWALTEAMRVLIADA
TH_2748|M.thermoresistible__bu --------------------------------------------------
Mflv_2951|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3562|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_3555|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
MSMEG_6525|M.smegmatis_MC2_155 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 TGGR--ALPGSVTVTYPAHWGPAAVAALDSALRRASEWSHGTSSTAQPLS
Rv2264c|M.tuberculosis_H37Rv TGGR--ALPGSVTVTYPAHWGPAAVAALDSALRRASEWSHGTSSTAQPLS
MMAR_3358|M.marinum_M TGGH--TLPASTAVAYPAHWTTSAVDALGAALGRVPEWSP----AGQPLL
MAV_4816|M.avium_104 GYG------APITIAVPAYWSDDQFAALREEFFAQSDLAR----EGVAPM
MAB_4291|M.abscessus_ATCC_1997 VSSANFTAPPVLSASIPAHWSPQTVSTLRDAIDRVPAFAP----GGRQLK
TH_2748|M.thermoresistible__bu --------------------------------------------------
Mflv_2951|M.gilvum_PYR-GCK -----------MSGPNPGE-----------------------------PD
Mvan_3562|M.vanbaalenii_PYR-1 -----------MSGPNPPEEPGGQP----------------------APD
MUL_3555|M.ulcerans_Agy99 -----------MSGPNPPGWEPDEPDPAGDSSAELEPFGD----TGDEPD
MLBr_00877|M.leprae_Br4923 -----------MSGPNPPGRENEESDSGNELSG------------ELDPH
MSMEG_6525|M.smegmatis_MC2_155 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 LLPDAAAALYAIRADPGIPARGIVAVCDFGGSGTGITLVDAADEYRPVAA
Rv2264c|M.tuberculosis_H37Rv LLPDAAAALYAIRADPGIPARGIVAVCDFGGSGTGITLVDAADEYRPVAA
MMAR_3358|M.marinum_M LIPDAAAALFAARANPGIPARGVVAVCDFGGSGTSITLADASGEYQPLGA
MAV_4816|M.avium_104 LVSDATAALAMLRGTPGFPSDGVIALCDFGAGGTTVTLMDGRAGFAPVGP
MAB_4291|M.abscessus_ATCC_1997 LIPDARAALEALAAGPGTPDRGVVVVCDLGGSGSSITLADAARGFQQIGQ
TH_2748|M.thermoresistible__bu --------------------------------------------------
Mflv_2951|M.gilvum_PYR-GCK NAA-------DNPDTG---------QTDFYSRAYSAPESEQFVS-AYSAA
Mvan_3562|M.vanbaalenii_PYR-1 DATRG----VDNPDTG---------QTDFYSRAYSAPESEQFVSPPYVPA
MUL_3555|M.ulcerans_Agy99 DALAGG-ELEPVSESGQIEPVDPAQESEAYSRAYSAPESEQFISGAYLPA
MLBr_00877|M.leprae_Br4923 NGVESVDELVPVPDSDLVTASDHTSETEVYSQAYSAPEAEHFTAVPYVPA
MSMEG_6525|M.smegmatis_MC2_155 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 TVRHQAFSGDLIDQSLLSYVMSELPGTGAFDPAGTSAIGSLTKLRIECRK
Rv2264c|M.tuberculosis_H37Rv TVRHQAFSGDLIDQSLLSYVMSELPGTGAFDPAGTSAIGSLTKLRIECRK
MMAR_3358|M.marinum_M TVRHPDFSGDLIDQSLLTYVMSEMPATGSFDPSGTSAIGSLNRLRAECRQ
MAV_4816|M.avium_104 SLRYTDFSGDAIDQLVLDHLLASDVSTAMR--GGSGRIGSQSRLLGACRR
MAB_4291|M.abscessus_ATCC_1997 TIRFADFSGQQIDQMLLTQVLTDLN----QDPEGTTSVGALTRLRDQCRL
TH_2748|M.thermoresistible__bu --------------------------------------------------
Mflv_2951|M.gilvum_PYR-GCK DIVPYDYDS-----------------------------------------
Mvan_3562|M.vanbaalenii_PYR-1 DASLYDYDT-----------------------------------------
MUL_3555|M.ulcerans_Agy99 DLSLYDYDG-----------------------------------------
MLBr_00877|M.leprae_Br4923 DLRLYDYD------------------------------------------
MSMEG_6525|M.smegmatis_MC2_155 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 AKERLSSSTVTTLTDALG---GDIRLTRNELEDTIRDSLDSVGRALEQTL
Rv2264c|M.tuberculosis_H37Rv AKERLSSSTVTTLTDALG---GDIRLTRNELEDTIRDSLDSVGRALEQTL
MMAR_3358|M.marinum_M AKEQLSLSTVATLSDALPGVSGEVRLTRNELDETIRDSLDGFARVVEHTL
MAV_4816|M.avium_104 AKEQLSTAVAVTVAGAPG---QGAQLTRAEFEQLISTPLDRFLDWCQEAL
MAB_4291|M.abscessus_ATCC_1997 AKERLSGDTATSVPVQLPGITTDVRLTRAELEGHLRGPLSNLINAIQDTV
TH_2748|M.thermoresistible__bu ------------------------------------------VAVSRPPE
Mflv_2951|M.gilvum_PYR-GCK -----------------------YDATEEPAEFAPPPRWPWVVGVVAIVA
Mvan_3562|M.vanbaalenii_PYR-1 -----------------------YDADAD-AELAPPPRWPWVVGIVAIVA
MUL_3555|M.ulcerans_Agy99 -----------------------YDDSLDEEDEPSTPRWPWVVGVAAIMA
MLBr_00877|M.leprae_Br4923 -------------------------ESSVYDEPGAAPRWPWVVGVAAILA
MSMEG_6525|M.smegmatis_MC2_155 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 ARSGIRTAELVAIVSVGGGANIPAVTTTLSGRFCVPVVRTPRPQLTAAFG
Rv2264c|M.tuberculosis_H37Rv ARSGIRTAELVAIVSVGGGANIPAVTTTLSGRFCVPVVRTPRPQLTAAFG
MMAR_3358|M.marinum_M QRAGVPAADLVAIVTVGGGANIPSVTTTLSGRFGVPVITAPRPQLTAATG
MAV_4816|M.avium_104 RRNGIGNSTLRGVAIVGGGASIPLLTARLSGRFGVPVHSTAQPGLSAALG
MAB_4291|M.abscessus_ATCC_1997 ERNGIHPANITAVASVGGGASIPLVTQQLSERMRVPVITAPQPQLAAARG
TH_2748|M.thermoresistible__bu DPSNYSDSEPTAYSDYTAGGSGGYVPGYGGGEYGGPPGPPEEP-------
Mflv_2951|M.gilvum_PYR-GCK AVALVVSVSVLVTRTDTDNLATPETTTRQAPPVQDEILTTTPPPPPPP--
Mvan_3562|M.vanbaalenii_PYR-1 AIALVVSVSVLVTRSDTDNLATPQTTTRPAPPVQDEFTTTEPPPPP----
MUL_3555|M.ulcerans_Agy99 AIALVASVSLLVTRTDSTKLANPATTS-SVPPVQDEITTTKPPPPP----
MLBr_00877|M.leprae_Br4923 AISLVVSVSLLFTRTDTSKLSTP-TTGRSTPPVQDEITTVKPPPPS----
MSMEG_6525|M.smegmatis_MC2_155 ---MSEREAGGSFDYLWEELTPPPVPEQNGFDAFDDNTWDFKP-------
. *
Mb2287c|M.bovis_AF2122/97 GALWAAR---RPGDTSATVLTAVTSAT------------ATAPADAPASV
Rv2264c|M.tuberculosis_H37Rv GALWAAR---RPGDTSATVLTAVTSAT------------ATAPADAPASV
MMAR_3358|M.marinum_M GALRAAR---GPGDSSATVLTSAAPMTQTAMAPLDPDVGAVAAADAPVSA
MAV_4816|M.avium_104 AATLGAQ---YASGAAPTAAAAAAVETPTEMVGAGGLDMTQAAWAAQATD
MAB_4291|M.abscessus_ATCC_1997 VALLATRPDLPPQDATAMRPVEQPPGDATMMRPVPTGTGTFAAPVAAAAN
TH_2748|M.thermoresistible__bu --------------------------------------------------
Mflv_2951|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3562|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_3555|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
MSMEG_6525|M.smegmatis_MC2_155 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 LQPALAWSEADEDSHIGP--------------------APGYTAARPSLS
Rv2264c|M.tuberculosis_H37Rv LQPALAWSEADEDSHIGP--------------------APGYTAARPSLS
MMAR_3358|M.marinum_M LQPALAWSEADDQSRAMPVVGD------------DYSGASGYTSARPQLT
MAV_4816|M.avium_104 VDDALAWSQDADTS-DEP---------------------VPYTGRDATGE
MAB_4291|M.abscessus_ATCC_1997 EEPELAWSQDDSAPDLAPLQETGYQSGYTVDLDDEYQGPTEATTARPELR
TH_2748|M.thermoresistible__bu --------------------------------------------------
Mflv_2951|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3562|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_3555|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
MSMEG_6525|M.smegmatis_MC2_155 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 FDHDAHAEPE--PKSPPIPWYRLPAVIITGTTVAVLLVGAAVAIGLSTGD
Rv2264c|M.tuberculosis_H37Rv FDHDAHAEPE--PKSPPIPWYRLPAVIITGTTVAVLLVGAAVAIGLSTGD
MMAR_3358|M.marinum_M FEENARAEPA--PKSVVIPWYRLPGVIIVATVVAVLLVGAAVAIALSSGE
MAV_4816|M.avium_104 YASEARRFDD--VAAGGLPWYKR-----TALVLSVAGAGAAVLIALVLAI
MAB_4291|M.abscessus_ATCC_1997 FSHGPYADEDDYDDYPPLPWYRRPLVWFIAAAAVAGIAFTGMMVSLTSSE
TH_2748|M.thermoresistible__bu ----------------PVPWYRKP------AALVAFGALGAVLLGLIVFA
Mflv_2951|M.gilvum_PYR-GCK --------PPTTEPPPPPPP--------PETVTVTQPPPPPP--AEAPPP
Mvan_3562|M.vanbaalenii_PYR-1 ----------TTEPPPPPP----------ETVTVTEPPPPPPETTAAPPP
MUL_3555|M.ulcerans_Agy99 ------------PPPPPPPSTEIPTATETQTVTVTPPPPPPPPPETSAAP
MLBr_00877|M.leprae_Br4923 -----------TETSTATET---------QTVTVT-PLPPPS--ATSTAV
MSMEG_6525|M.smegmatis_MC2_155 ---------------APVPWYRTRG----AAVALTAAGIAAAAIVVSLVL
. .
Mb2287c|M.bovis_AF2122/97 QPTAPGTPQR---PGVTTTAAPPPSPAPASDGPTTEPAPPVQAPATGGPA
Rv2264c|M.tuberculosis_H37Rv QPTAPGTPQR---PGVTTTAAPPPSPAPASDGPTTEPAPPVQAPATGGPA
MMAR_3358|M.marinum_M QP-ATRSPEA---TTSPPTSAPAAVP-PVTDAGTSAPAPSTQPPASQEPA
MAV_4816|M.avium_104 NLLLTKSTQ-------DRPTSPPSTPAPPQTVTITGPNDSTTVTVVPAPP
MAB_4291|M.abscessus_ATCC_1997 SPAPATTTPS---VNVVPSTGDAPAEPPPSPEPPPPPQTHTVTQSVQ-PP
TH_2748|M.thermoresistible__bu LIRLTSGDD------ASSETATTTTTTTTTTGAPVAPPPATVTQTVPPAT
Mflv_2951|M.gilvum_PYR-GCK PPPQTTEAPP---PPPTTTTPAGPRQVTYSVTGTKAPGDIITVTYIDASG
Mvan_3562|M.vanbaalenii_PYR-1 PPPATTEPPP---PPPTTTTRAGPRQVTYSVTGTKAPGDIITVTYIDASG
MUL_3555|M.ulcerans_Agy99 PPAATTPTTPAAAPPPTTTTPAGPRQVTYSVTGTKAPGDIISVTYVDASG
MLBr_00877|M.leprae_Br4923 PPSSVVPPPP-TTPTTTVTTLTGPRQVTYSVTGTKAPGDIISVTYVDASG
MSMEG_6525|M.smegmatis_MC2_155 LLLRDTSPVD------DEQTTTVTPTTTATIAPSPSLRVGVPPAAPPPPP
: . . .
Mb2287c|M.bovis_AF2122/97 PPLQQPLPPPPTTTNTQPAVTTDVITPAPTTPASAPPATTQPPATTQPPA
Rv2264c|M.tuberculosis_H37Rv PPLQQPLPPPPTTTNTQPAVTTDVITPAPTTPASAPPATTQPPATTQPPA
MMAR_3358|M.marinum_M PPPTQQAPPPPSTEAPPPSTTQAPVTTQPPATTEAPPATTQPPVTTEAPP
MAV_4816|M.avium_104 PPSSEAPPPPATTTTAPPEPSTTTTTTTP--PPSSTTTTSAAPTTTAQPS
MAB_4291|M.abscessus_ATCC_1997 PPSPEPPPPPPPTTTTTTTPPTTTTTTTTTTTTTTTTTTTPTTTTTQPTT
TH_2748|M.thermoresistible__bu TTPAEEPSPPPTTTQTPTTTTTTTTTTTTESPTTTTTTETVTQTETETQT
Mflv_2951|M.gilvum_PYR-GCK RSRTQRNVYIPWSLTVTPISQSEVGSVQASSLFLVSKLNCSITTSDGQVL
Mvan_3562|M.vanbaalenii_PYR-1 RSRTQRNVYIPWSLTVTPISQSEVGSVQASSLFMVSRLNCSITTSDGTVL
MUL_3555|M.ulcerans_Agy99 RRRTQHNVYIPWSMTVTPISQSDVGSVEASSLFRVSRLNCSITTSDGTVL
MLBr_00877|M.leprae_Br4923 RRRTQHNVYIPWSMTVTPISQSDVGSVEAFSLFRVSKLNCLITTSDGTVL
MSMEG_6525|M.smegmatis_MC2_155 PTTQEEEAPRQAPVYRPPQRQRESTKKPEIGVTRTPVTRSPISVAPQQRA
: . . . . .
Mb2287c|M.bovis_AF2122/97 TTS-------PSPPPIPPIPPIPEIPQLP----PGIPQVPGIGQFSAISG
Rv2264c|M.tuberculosis_H37Rv TTS-------PSPPPIPPIPPIPEIPQLP----PGIPQVPGIGQFSAISG
MMAR_3358|M.marinum_M TTQAPATQQLPTPPPIPPIPQIPPIPQIPGIGFPQVPQVPQIPQVPQVPG
MAV_4816|M.avium_104 TTS--------AAPTTTRVRPIPPIFQPP------------FGR------
MAB_4291|M.abscessus_ATCC_1997 TTT-------QPTSTSRPAITIPGLPPIP------------IGPRN----
TH_2748|M.thermoresistible__bu VTA---------PPDEGE--------------------------------
Mflv_2951|M.gilvum_PYR-GCK SSN---------TGNAAQTSC-----------------------------
Mvan_3562|M.vanbaalenii_PYR-1 SSN---------TSNAAQTSC-----------------------------
MUL_3555|M.ulcerans_Agy99 SSN---------SNDAPQTSC-----------------------------
MLBr_00877|M.leprae_Br4923 SSN---------SNDAPQTSC-----------------------------
MSMEG_6525|M.smegmatis_MC2_155 PRN-----------------------------------------------
Mb2287c|M.bovis_AF2122/97 S-------------------------
Rv2264c|M.tuberculosis_H37Rv S-------------------------
MMAR_3358|M.marinum_M VPGFGQVIAPQVIAPQVIAPQAANGQ
MAV_4816|M.avium_104 --------------------------
MAB_4291|M.abscessus_ATCC_1997 --------------------------
TH_2748|M.thermoresistible__bu --------------------------
Mflv_2951|M.gilvum_PYR-GCK --------------------------
Mvan_3562|M.vanbaalenii_PYR-1 --------------------------
MUL_3555|M.ulcerans_Agy99 --------------------------
MLBr_00877|M.leprae_Br4923 --------------------------
MSMEG_6525|M.smegmatis_MC2_155 --------------------------