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M. smegmatis MC2 155 MSMEG_6313 (tgt)

annotation: queuine tRNA-ribosyltransferase
coordinates: 6379351 - 6380595
length: 414

DQPYFTVTAELEGRLGRVGTIHTPHGDIHTPAFIPVGTAATVKSVLPETMKQLGAQAILANAYHLYLQPG
PDIVAEAGGLGAFMNWPGPTFTDSGGFQVLSLGVGFKKVLAMDTNRVQADDIIAEGKERLAHVDDDGVTF
RSHLNGSLHRFTPEVSIGIQYQLGADIIFAFDELTTLVNTRAYQERSVQRTHEWAERCLAEHHRLQNQAP
ERPRQALFGVVQGAQYEDLRRKAARGLATIGEQAGPAEGLAFDGYGIGGALEKQNLATIVGWVSSELPKD
KPRHMLGISEPDDLFAAVAAGADTFDCVSPSRVARNAAIYTSTGRYNITGARYKRDFTPLDPECDCYTCA
NYSRAYIRHLFKAKEMLSATLCTIHNERFVVRLVDRIRAAMLAGEFDALRDEVLGRYYGTSVR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_6313tgt-100% (414)queuine tRNA-ribosyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_1228-0.082.84% (402) queuine tRNA-ribosyltransferase
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0275-0.076.35% (406) queuine tRNA-ribosyltransferase (TGT)
M. marinum M-----
M. avium 104-----
M. thermoresistible (build 8)TH_1651tgt0.083.05% (407) queuine tRNA-ribosyltransferase
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_5580-0.082.09% (402) queuine tRNA-ribosyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1228|M.gilvum_PYR-GCK          -----------MTAELPGRLGRTGVIRTPHGEIRTPAFIAVGTQATVKAV
Mvan_5580|M.vanbaalenii_PYR-1       -----------MDVELPGRLGRTGTIRTPHGDIQTPAFIAVGTQATVKAV
MSMEG_6313|M.smegmatis_MC2_155      ----MDQPYFTVTAELEGRLGRVGTIHTPHGDIHTPAFIPVGTAATVKSV
TH_1651|M.thermoresistible__bu      VTSDSSGPFFSVGTELPGRLGRTGVIRTPHGEIHTPAFIPVGTQATVKAV
MAB_0275|M.abscessus_ATCC_1997      ----MTDPYFSIDATLSGTAGRAGVIHTPHGDIQTPAFIAVGTKATVKAV
                                               : . * *  **.*.*:****:*:*****.*** ****:*

Mflv_1228|M.gilvum_PYR-GCK          LPETMKQVGAQAVLANAYHLYLQPGPDIVDEAGGLGAFMNWPGPTFTDSG
Mvan_5580|M.vanbaalenii_PYR-1       LPETMKEIGAQAVLANAYHLYLQPGADVVDEAGGLGAFMNWPGPTFTDSG
MSMEG_6313|M.smegmatis_MC2_155      LPETMKQLGAQAILANAYHLYLQPGPDIVAEAGGLGAFMNWPGPTFTDSG
TH_1651|M.thermoresistible__bu      LPETMKELGAQAVLANAYHLYLQPGPDIVAEAGGLGAFMNWPGPTFTDSG
MAB_0275|M.abscessus_ATCC_1997      LPETMAALGAQAVLANAYHLYLQPGPDIVDEAGGLGAFMNWPGPTFTDSG
                                    *****  :****:************.*:* ********************

Mflv_1228|M.gilvum_PYR-GCK          GFQVMSLGVGFKKVLAMDTERVRADDIIAEGKERLAHVDDDGVTFRSHLD
Mvan_5580|M.vanbaalenii_PYR-1       GFQVMSLGVGFKKVLAMDTSRVQADDIIAEGKSRLAHVDDDGVTFRSHLN
MSMEG_6313|M.smegmatis_MC2_155      GFQVLSLGVGFKKVLAMDTNRVQADDIIAEGKERLAHVDDDGVTFRSHLN
TH_1651|M.thermoresistible__bu      GFQVLSLGAGFRKVLAMDANRVQADDVIAEGKERLAHVDDDGVTFRSHLD
MAB_0275|M.abscessus_ATCC_1997      GFQVLSLGSGVRKVMAMDVNRARADDVTVAGKDKLAHVDDDGVTFTSHLD
                                    ****:*** *.:**:***..*.:***: . **.:*********** ***:

Mflv_1228|M.gilvum_PYR-GCK          GSSHRFTPEVSIGIQHQLGADIIFAFDELTTLVNTREYQESSVQRTHEWA
Mvan_5580|M.vanbaalenii_PYR-1       GSSHRFTPEVSIGIQHQLGADIIFAFDELTTLVNTRGYQERSVQRTHDWA
MSMEG_6313|M.smegmatis_MC2_155      GSLHRFTPEVSIGIQYQLGADIIFAFDELTTLVNTRAYQERSVQRTHEWA
TH_1651|M.thermoresistible__bu      GSTHRFTPEKSIGIQRRLGADIIFAFDELTTLVNTRGYQERSVRRTHEWA
MAB_0275|M.abscessus_ATCC_1997      GSAHRFTPEVSMQIQHQLGADIMFAFDELTTLINTREYQEDSVQRTHEWA
                                    ** ****** *: ** :*****:*********:*** *** **:***:**

Mflv_1228|M.gilvum_PYR-GCK          VRCLVEHRRLSDVRSHTPQQALFGVVQGAQYEDLRRQAARGLTGIVD---
Mvan_5580|M.vanbaalenii_PYR-1       VRCLAEHRRLSRVRSHTPPQALFGVVQGAQYEDLRRQAARGLTQIVD---
MSMEG_6313|M.smegmatis_MC2_155      ERCLAEHHRLQNQAPERPRQALFGVVQGAQYEDLRRKAARGLATIGEQAG
TH_1651|M.thermoresistible__bu      VRCLVEHHRLRAAHPELPRQALFGVVQGAQYEDLRRQAARGLTEIGAGPG
MAB_0275|M.abscessus_ATCC_1997      QRCLDEHEKLTRERADKPYQALFGVVQGAQYEDLRRQAARGLESLAG---
                                     *** **.:*    .. * *****************:*****  :     

Mflv_1228|M.gilvum_PYR-GCK          -EHGRGFDGYGIGGALEKQNLATIVGWVSSELPDDKPRHLLGISEPDDLF
Mvan_5580|M.vanbaalenii_PYR-1       -EEGRGFDGYGIGGALEKQNLATIVGWVSSELPDDKPRHLLGISEPDDLF
MSMEG_6313|M.smegmatis_MC2_155      PAEGLAFDGYGIGGALEKQNLATIVGWVSSELPKDKPRHMLGISEPDDLF
TH_1651|M.thermoresistible__bu      PAEGLGFDGYGIGGALEKQNLATIVGWVSSELPPDKPRHLLGISEPDDLF
MAB_0275|M.abscessus_ATCC_1997      -PSGRGFDGYGIGGALEKQNLGTIVGWVTSELPEHKPRHLLGISEPDDLF
                                       * .***************.******:**** .****:**********

Mflv_1228|M.gilvum_PYR-GCK          AAVEAGADTFDCVSPSRVARNAAVYSADGRYNITGARYRRDFTPIDAECD
Mvan_5580|M.vanbaalenii_PYR-1       AAIEAGADTFDCVSPSRVARNAAVYSADGRFNITGSRYRRDFTPIDAECD
MSMEG_6313|M.smegmatis_MC2_155      AAVAAGADTFDCVSPSRVARNAAIYTSTGRYNITGARYKRDFTPLDPECD
TH_1651|M.thermoresistible__bu      AAVAAGADTFDCVSPSRVARNAAVYSSTGRFNVTNARFRRDFNPIDDGCD
MAB_0275|M.abscessus_ATCC_1997      AAVAAGADTFDCVSPSRVARNAAVYTRDGRVNITGARYRRDFTPIDAECD
                                    **: *******************:*:  ** *:*.:*::***.*:*  **

Mflv_1228|M.gilvum_PYR-GCK          CYTCANYTRAYLHHLFKAKELLAATLCTIHNERFIIRLVDDIRASIPAGR
Mvan_5580|M.vanbaalenii_PYR-1       CYTCTHYTRAYLHHLFKAKEMLSATLCTIHNERFVIRLVDDIRVAIREGR
MSMEG_6313|M.smegmatis_MC2_155      CYTCANYSRAYIRHLFKAKEMLSATLCTIHNERFVVRLVDRIRAAMLAGE
TH_1651|M.thermoresistible__bu      CYTCAHYTRAYLHHLFKARELLSATLATIHNQRFIIRLVDRIRESIVAGE
MAB_0275|M.abscessus_ATCC_1997      CYTCAHYTRAYMHHLFKAKEILASTLATIHNERFTIGLVDRIRASIVEGC
                                    ****::*:***::*****:*:*::**.****:** : *** ** ::  * 

Mflv_1228|M.gilvum_PYR-GCK          FDELREHVLGRYYAAKS-------
Mvan_5580|M.vanbaalenii_PYR-1       FDELREHVLGRYYAKA--------
MSMEG_6313|M.smegmatis_MC2_155      FDALRDEVLGRYYGTSVR------
TH_1651|M.thermoresistible__bu      FDELREHTLGRYYGGRRRYGTMAT
MAB_0275|M.abscessus_ATCC_1997      FQELREDTLGRYYR----------
                                    *: **:..*****