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M. smegmatis MC2 155 MSMEG_6220 (-)

annotation: lipoprotein
coordinates: 6283315 - 6284637
length: 440

MVLTGRTGLVALVCVLPIAVSPWPATAFGALLVLLLAAVGADVALAGSPRRLHVQRGGDHTARLGQTVDT
VVEIHNPGRRPVRGQVRDAWPPSACAQPRVHPLDAAAAEQVRLVTRLQPVRRGDQRSETVTVRSIGPLGL
AGRQAVHRVPHQVRILPPFLSRKHLPSRLARLRELDGAIPVLIRGQGTEFDSLREYVVGDDVRSIDWRAT
ARRADVVVRTWRPERDRRVVIVLDTGRTSAGRVGVDPTASDPGGWPRLDWSMDAALLLAALASRAGDHVD
FLAFDRVTRAGVFNASRTELMSALVGAMAPLQPALVESDATALVSTITRRVRGRSLVVLLTDLNASALDE
GLMAVLPQLSARHQILLAAVSDPRVDDLAAGRSDAAAVYDAAAAERSRNDRRAIAARLRRRGVDVVDAPP
EDLAPALADHYLALKATGKL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_6220--100% (440)lipoprotein
M. smegmatis MC2 155MSMEG_6610-2e-1427.16% (243) protein of unknown function DUF58, putative
M. smegmatis MC2 155MSMEG_3148-4e-1226.32% (285) hypothetical protein MSMEG_3148

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3718-0.074.77% (440) hypothetical protein Mb3718
M. gilvum PYR-GCKMflv_1336-0.072.95% (440) hypothetical protein Mflv_1336
M. tuberculosis H37RvRv3693-0.074.77% (440) hypothetical protein Rv3693
M. leprae Br4923MLBr_01809-3e-1228.10% (242) hypothetical protein MLBr_01809
M. abscessus ATCC 19977MAB_0388c-1e-16365.11% (450) hypothetical protein MAB_0388c
M. marinum MMMAR_5203-0.075.45% (440) hypothetical protein MMAR_5203
M. avium 104MAV_0411-0.076.14% (440) lipoprotein
M. thermoresistible (build 8)TH_1716-0.076.14% (440) POSSIBLE CONSERVED MEMBRANE PROTEIN
M. ulcerans Agy99MUL_4276-0.075.45% (440) hypothetical protein MUL_4276
M. vanbaalenii PYR-1Mvan_5456-0.074.15% (441) hypothetical protein Mvan_5456

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_6220|M.smegmatis_MC2_155      MVLTGRTGLVALVCVLPIAVSPWPATAFGALLVLLLAAVGADVALAGSPR
TH_1716|M.thermoresistible__bu      MIVTGRTALVAAVAILPIAVSPWPAMAFAALLSLLVVAVVVDAALAANPR
Mflv_1336|M.gilvum_PYR-GCK          MILTGRAGLLALLCAVPVLSSPSPAVVFWTLAGLLTIAIVCDVALAGSPR
Mvan_5456|M.vanbaalenii_PYR-1       MVLTGRAGLIALLCALPVVLSPYPAATFAVLAALLAVAVLADVALAGSPR
Mb3718|M.bovis_AF2122/97            MILTGRTGLLALICVLPIALSPWPARAFVMLLVALAVAVTVDTLLAASTR
Rv3693|M.tuberculosis_H37Rv         MILTGRTGLLALICVLPIALSPWPARAFVMLLVALAVAVTVDTLLAASTR
MMAR_5203|M.marinum_M               MILTGRTGLMALIGVLPIALSPWPPRAFGMLLLALAVAVAIDVALAASPR
MUL_4276|M.ulcerans_Agy99           MILTGRTGLMALIGVLPIALSPWPPRAFGMLLLALAVAVAIDVALAASPR
MAV_0411|M.avium_104                MILTGRTGLVALICVLPIALSPWPAMVFTALLAALAVAVAVDAALAASPA
MAB_0388c|M.abscessus_ATCC_199      MVLTGRAGLVAALSTLLILVSPWPVRLFWLLLLALALLIAVDIAAAASPR
MLBr_01809|M.leprae_Br4923          ---------------------------------------MIDPNPAAKPG
                                                                             *   *... 

MSMEG_6220|M.smegmatis_MC2_155      RLHVQRGGDHTARLGQTVDTVVEIHNPGRRPVRGQVRDAWPPSACAQPRV
TH_1716|M.thermoresistible__bu      QLLFSRSGESTARLGQSVDALLEVANGGGRRLRGRLRDAWPPSARAEPRL
Mflv_1336|M.gilvum_PYR-GCK          ALRLTRGGPTSARLGQPVTVDLTVENGGRARFRGVVRDAWAPSARAHPRT
Mvan_5456|M.vanbaalenii_PYR-1       ALELTRGGPTSARLGQPVTAELTVRNSGRARFRGLVRDAWAPSARGAPRV
Mb3718|M.bovis_AF2122/97            KLRFTRSPYTSARLGQPVDASLLLCNGGRRRFRGQVRDAWPPSARAQPHT
Rv3693|M.tuberculosis_H37Rv         KLRFTRSPYTSARLGQPVDASLLLCNGGRRRFRGQVRDAWPPSARAQPHT
MMAR_5203|M.marinum_M               KLSYTRGANSSIRLGQPADAALVIHNVGRRRFRGLVRDAWPPSARAQPRT
MUL_4276|M.ulcerans_Agy99           KLSYTRGANSSIRLGQPADAALVIHNVGRRRFRGLVRDAWPPSARAQPRT
MAV_0411|M.avium_104                RLRCIRSPDRSARLGQHADAALLIHNDGPRRFRGQIRDAWPPSARARPRL
MAB_0388c|M.abscessus_ATCC_199      RLTFTRSGPDSIRLGESAEIVLLAQNPG-RRLRGWVRDSWAPSMRAAPRA
MLBr_01809|M.leprae_Br4923          VFHPPSMQ------------------------RGQIDD---PKLSAALRT
                                     :                              ** : *   *.  .  : 

MSMEG_6220|M.smegmatis_MC2_155      HPLDAAAAEQVRLVTRLQPVRRGDQRSETVTVRSIGPLGLAGRQAVHRVP
TH_1716|M.thermoresistible__bu      HALHLDPGQRVRLRTTLRPTRRGDQHSALVTVRTLGPAGLAGRQRSHRVP
Mflv_1336|M.gilvum_PYR-GCK          HAVDLPVGQRVRISTELTPARRGDQVSALVTARSVGPLGLAGRQGSHRVP
Mvan_5456|M.vanbaalenii_PYR-1       HRVNIAAGQRVLLETELRPVRRGDQVSALVTARAIGPLGLAGRQGSHRVP
Mb3718|M.bovis_AF2122/97            HDVDVAAGQRQQVHTALRPVRRGDQRAAMVTARSIGPLGLAGRQSSQSVP
Rv3693|M.tuberculosis_H37Rv         HDVDVAAGQRQQVHTALRPVRRGDQRAAMVTARSIGPLGLAGRQSSQSVP
MMAR_5203|M.marinum_M               HPINIAAGERQQVNTALQPVRRGDQHCAAVTARSIGPLGLAGRQRSQVVP
MUL_4276|M.ulcerans_Agy99           HPINIAAGERQQVNTALQPVRRGDQHCAAVTARSIGPLGLAGRQRSQVVP
MAV_0411|M.avium_104                HRVDIPAGQHQHIATRLEPVRRGDQRATVVTARSIGPLGLAGRQGSQSVP
MAB_0388c|M.abscessus_ATCC_199      HRVDLRSGERTQIVTTLRPLRRGDHKPATVTVRTIGPLGIAGRQGRHDVP
MLBr_01809|M.leprae_Br4923          LELTVKR--------KLDGVLHGDHLG-----------------------
                                      :             *    :**:                         

MSMEG_6220|M.smegmatis_MC2_155      HQVRILPPFLSRKHLPSRLARLRELDGAIPVLIRGQGTEFDSLREYVVGD
TH_1716|M.thermoresistible__bu      GRVRVLPPFLSRKHLPARLARLRDLEGAVPVLIRGQGTEFDSLREYVVGD
Mflv_1336|M.gilvum_PYR-GCK          WQVRILPPFLSRKHLPSRLARLRELEGMTPVLIRGQGTEFDSLREYVVGD
Mvan_5456|M.vanbaalenii_PYR-1       WQIRILPPFLSRKHLPSRLARLRELEGMTPVLIRGQGTEFDSLREYVVGD
Mb3718|M.bovis_AF2122/97            GLVRVLPPFLSRKHLPSRLAKLREIDGLLPTLIRGQGTEFDSLREYVVGD
Rv3693|M.tuberculosis_H37Rv         GLVRVLPPFLSRKHLPSRLAKLREIDGLLPTLIRGQGTEFDSLREYVVGD
MMAR_5203|M.marinum_M               GQVRVLPPFLSRKHLPSRLAKLREIDGLLPTLIRGQGTEFDSLREYVVGD
MUL_4276|M.ulcerans_Agy99           GQVRVLPPFLSRKHLPSRLAKLREIDGLLPTLIRGQGTEFDSLREYVVGD
MAV_0411|M.avium_104                GQLRVLPPFLSRKHLPSRLARLREIDGLLPTLVRGQGTEFDSLREYVVGD
MAB_0388c|M.abscessus_ATCC_199      WQLRVLPPFLSRKHLPSRLAKLRELEGAIPVLIRGQGTEFDSLREYVVGD
MLBr_01809|M.leprae_Br4923          -------------------------------LISGPGSEPGESRVYQPGD
                                                                   *: * *:* .. * *  **

MSMEG_6220|M.smegmatis_MC2_155      DVRSIDWRATARRADVVVRTWRPERDRRVVIVLDTGRTSAGRVGVDPTAS
TH_1716|M.thermoresistible__bu      DVRSIDWRATARKDDVVVRTWRPERDQRVVIALDTGRTSAGRVGVDPTGS
Mflv_1336|M.gilvum_PYR-GCK          DVRSIDWRATARRADVVVRTWRPERDRRVLIVLDTGRTSAGRVGVDPTLL
Mvan_5456|M.vanbaalenii_PYR-1       DVRSIDWRATARRADVVVRTWRPERDRRMLIVLDTGRTSAGRVGVDPTGS
Mb3718|M.bovis_AF2122/97            DVRSIDWRASARRADVMVRTWRPERDRRVVIVLDTGRMAAGRVGVDPTAA
Rv3693|M.tuberculosis_H37Rv         DVRSIDWRASARRADVMVRTWRPERDRRVVIVLDTGRMAAGRVGVDPTAA
MMAR_5203|M.marinum_M               DVRSIDWRASARRADVMVRTWRPERDRRVVLVLDTGRMAAGRVGVDPTDA
MUL_4276|M.ulcerans_Agy99           DVRSIDWRASARRADVMVRTWRPERDRRVVLVLDTGRMAAGRVGVDPTDA
MAV_0411|M.avium_104                DVRSIDWRATARRADVVVRTWRPERDRRVVIVLDTGRTAAGRVGVDPTAA
MAB_0388c|M.abscessus_ATCC_199      DVRSIDWRASARRNDVVVRTWRPERDRRILVVLDTGRTSAGRIGVDPTSG
MLBr_01809|M.leprae_Br4923          DVRRMDWAVTARTTHPHVRQMIADRELETWMVIDMS----ASLDFGTTIC
                                    *** :** .:**  .  **   .:*: .  :.:* .    . :....*  

MSMEG_6220|M.smegmatis_MC2_155      DPG-GWPRLDWSMDAALLLAALASRAGDHVDFLAFD--RVTRAGVFNASR
TH_1716|M.thermoresistible__bu      EPG-GWPRLDWSMDAALLLAALASRAGDRVDFLAHD--RELRAAVFNAPR
Mflv_1336|M.gilvum_PYR-GCK          DPG-GWPRLDWSMDAALLLAALAARAGDHVDLLAHD--RETRAAVVNASR
Mvan_5456|M.vanbaalenii_PYR-1       DPATGWPRLDWSMDAALLLAALAARAGDHVDFLAHD--RETCAAVVNASR
Mb3718|M.bovis_AF2122/97            DPA-GWPRLDWSMDAALLLAALASRAGDHVDFLAHD--RISRAGVFGASR
Rv3693|M.tuberculosis_H37Rv         DPA-GWPRLDWSMDAALLLAALASRAGDHVDFLAHD--RISRAGVFGASR
MMAR_5203|M.marinum_M               DPA-GWPRLDWSMDAALLLAALASRAGDHVDFLAHD--RVSRAAVFGASR
MUL_4276|M.ulcerans_Agy99           DPA-GWPRLDWSMDAALLLAALASRAGDHVDFLAHD--RVSRAAVFGASR
MAV_0411|M.avium_104                DPA-GWPRLDWSMDAALLLAALASRAGDHVDFLAHD--RVGRAGVFGASR
MAB_0388c|M.abscessus_ATCC_199      DPS-GWPRLDWAMDAALLLVALASRAGDRVDFLAHD--RGVRAQVSGASR
MLBr_01809|M.leprae_Br4923          EKR------DLAVAAAAAITFLNSGGGNRLGALICNGARMTRVPARSGRQ
                                    :        * :: **  :. * : .*:::. *  :  *   . . .. :

MSMEG_6220|M.smegmatis_MC2_155      TELMSALVGAMAPLQPALVESDATALVSTITRRVRGRSLVVLLTDLNASA
TH_1716|M.thermoresistible__bu      TELLARLVDAMAPLQPALVESDASALVAEVQRRVRRRALVVLLTDLNASA
Mflv_1336|M.gilvum_PYR-GCK          TELLAQLVSAMAPLEPALVESDARGMVAAVQRRVRRAALVVLLTDLNASA
Mvan_5456|M.vanbaalenii_PYR-1       TELLAQLVAAMAPLEPSLIESDARAMVAAVQRRVRRRALVVLLTDLNASA
Mb3718|M.bovis_AF2122/97            SELLAQLVDAMAPLRPALIESDWHAMIATILRRTRRRSLVVLLTDLNATA
Rv3693|M.tuberculosis_H37Rv         SELLAQLVDAMAPLRPALIESDWHAMIATILRRTRRRSLVVLLTDLNATA
MMAR_5203|M.marinum_M               TELLAQLVDAMAPLQPALVESDWRSMVATIARRTRRRSLVVLLTDLNATA
MUL_4276|M.ulcerans_Agy99           TELLAQLVDAMAPLQPALVESDWRSMVATIARRTRRRSLVVLLTDLNATA
MAV_0411|M.avium_104                TELLAQLVDAMAPLQPTLVETDWRAMVSAIALRARRRSLVVLLTDLNAAA
MAB_0388c|M.abscessus_ATCC_199      NELLPLVVNAMAPLEPSLVESDARGLVSTIRRRSRHRSLIVLLTDLNPAA
MLBr_01809|M.leprae_Br4923          HEQTLLRTIATTPKAPVGVRGDLTVAIDALRRPERRRGMAVIISDFLG--
                                     *     . * :*  *  :. *    :  :    *  .: *:::*:    

MSMEG_6220|M.smegmatis_MC2_155      LDEGLMAVLPQLSARHQILLAAVSDPRVDDLAAGR----------SDAAA
TH_1716|M.thermoresistible__bu      LDEGLMGVLPQLTARHKVLLAAVADPRVDQLAAGR----------ADAAQ
Mflv_1336|M.gilvum_PYR-GCK          LDEGLLSVLPQLTAKHRVIVAAVADPRVEKLAAGR----------ADAVE
Mvan_5456|M.vanbaalenii_PYR-1       IDEGLLKVLPQLTAKHRVIVAAVADPRVDTLAAGR----------ADAVE
Mb3718|M.bovis_AF2122/97            LDEGLLPVLPQLSARHHVLVAAVADPRVDQLAAGR----------SDAAA
Rv3693|M.tuberculosis_H37Rv         LDEGLLPVLPQLSARHHVLVAAVADPRVDQLAAGR----------SDAAA
MMAR_5203|M.marinum_M               LDEGLLPVLPQLSAKHQVVVAAVADPRVDQLAIGR----------SDAAA
MUL_4276|M.ulcerans_Agy99           LDEGLLPVLPQLSAKHQVVVAAVADPRVDQLAIGR----------SDAAA
MAV_0411|M.avium_104                LDEGLLPVLPQLSAKHHLLVAAVADPRVDQMAAGR----------SDAAA
MAB_0388c|M.abscessus_ATCC_199      LEEGLLPLLSQLTTHHHLLVAAVSDPRVEDMVTPANATGPGNIRSLDAEQ
MLBr_01809|M.leprae_Br4923          -PINWMRPLRAIAARHEVLGIEVLDPRDVALPDIG--EVVLQDAETGVTR
                                       . :  *  ::::*.::   * ***   :               ..  

MSMEG_6220|M.smegmatis_MC2_155      VYDAAAAERSRNDRRA------IAARLRRRGVDVVDAPPEDLAPALADHY
TH_1716|M.thermoresistible__bu      VYDAASAERSRNERRA------IAMRLRRHGVEVVDAPPEELAPALADHY
Mflv_1336|M.gilvum_PYR-GCK          VYDAAAAERARNDRSA------VASRLRSLGVDVVDSPPEELAPDLADHY
Mvan_5456|M.vanbaalenii_PYR-1       VYDAAAAERARNDRRA------VASRLRAMGVDVVDAPPEDLAPDLADHY
Mb3718|M.bovis_AF2122/97            VYDAAAAERARNDRRA------IASQLRRGGVDVIDAPPAEIAPGLADRY
Rv3693|M.tuberculosis_H37Rv         VYDAAAAERARNDRRA------IASQLRRGGVDVIDAPPAEIAPGLADRY
MMAR_5203|M.marinum_M               VYDAAAAERARNDRGT------IAARLRRSGVEVVDAPPTEIAPALADRY
MUL_4276|M.ulcerans_Agy99           VYDAAAAERARNDRGT------IAARLRRSGVEVVDAPPTEIAPALADRY
MAV_0411|M.avium_104                VYDAAAAERSRNERAA------IAARLRHGGVEVVDAAPAELAPALADHY
MAB_0388c|M.abscessus_ATCC_199      VYDAAAAERTRGGRRR------IVTLLRRQGVEVVDAPPDEIAPALADRY
MLBr_01809|M.leprae_Br4923          EFTIDAALRDDFARAAAAHCADVSRSLRNCGAPLMSLRTDRDWIADIVRF
                                     :   :* *    *        :   **  *. ::.  .         ::

MSMEG_6220|M.smegmatis_MC2_155      LALKATGKL----
TH_1716|M.thermoresistible__bu      LAIKAAGRL----
Mflv_1336|M.gilvum_PYR-GCK          LAMKATGRL----
Mvan_5456|M.vanbaalenii_PYR-1       LAMKAAGRL----
Mb3718|M.bovis_AF2122/97            LAMKATGRL----
Rv3693|M.tuberculosis_H37Rv         LAMKATGRL----
MMAR_5203|M.marinum_M               LAMKATGRL----
MUL_4276|M.ulcerans_Agy99           LAMKATGRL----
MAV_0411|M.avium_104                LAMKATGRL----
MAB_0388c|M.abscessus_ATCC_199      LSLKASGRL----
MLBr_01809|M.leprae_Br4923          VESRRRGALAGRQ
                                    :  :  * *