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MDAGPMKIRNLRWIVPTAVVIVVLAVLTVYLTAPRPGGRMDPDSTSPEGARALVTLLRDHGVDVITATGI DDVERDARPGTLLVAAQTLFLSGDDQLERLSQVPGDLLLVEPTTKTREKLAPAIRPDDAAAFGGGEPDCD LPEARRAGETQLGLSNTFRAAGDIPVQRCYDGAVVRYRDGNRTVTVVGTAEFMSNSGLLKEGNAALAMNL AGDRDRVIWYSPQKFEGTSTGDRKLSDLMPDQVRWIVLQLCVVVALFALWQARRLGPLVAESLPVVVRAS ETVEGRGKLYRSHRARDRAADALRTATLQRLLPRLGLTAQADQAAVAAAVAVRCGQDSQTVGYTLFGPPP GTDDELVHLAHRLDDIERQVAHS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6218 | - | - | 100% (373) | secreted protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3716 | - | 1e-103 | 57.49% (334) | hypothetical protein Mb3716 |
| M. gilvum PYR-GCK | Mflv_1338 | - | 1e-121 | 61.35% (370) | hypothetical protein Mflv_1338 |
| M. tuberculosis H37Rv | Rv3691 | - | 1e-103 | 57.49% (334) | hypothetical protein Rv3691 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0390c | - | 1e-83 | 45.97% (372) | hypothetical protein MAB_0390c |
| M. marinum M | MMAR_5201 | - | 1e-116 | 59.67% (362) | hypothetical protein MMAR_5201 |
| M. avium 104 | MAV_0413 | - | 1e-109 | 55.71% (368) | hypothetical protein MAV_0413 |
| M. thermoresistible (build 8) | TH_4091 | - | 1e-115 | 58.86% (367) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4274 | - | 1e-115 | 59.39% (362) | hypothetical protein MUL_4274 |
| M. vanbaalenii PYR-1 | Mvan_5454 | - | 1e-123 | 61.48% (366) | hypothetical protein Mvan_5454 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3716|M.bovis_AF2122/97 -----------------------------------------------MAP
Rv3691|M.tuberculosis_H37Rv -----------------------------------------------MAP
MMAR_5201|M.marinum_M -MPARAESAHAPGRQRKPWRGVLLTLAAVTVIASIATYLTAPRPGGTMDP
MUL_4274|M.ulcerans_Agy99 -MPARAESAHTPSRKRKPWRGVLLTLAAVTVIASIATYLTAPRPGGTMDP
MAV_0413|M.avium_104 -MATTTATATAP-RRRRSWRWVLATLLVLAVIAGVDAYLSAPRPGTRMDA
Mflv_1338|M.gilvum_PYR-GCK MNASTTAVGSTIPERWRTLRWVLLGLAAIVAVAALSTWLTAPRDGGRLDP
Mvan_5454|M.vanbaalenii_PYR-1 ---MSTAVGATITDRWRGLRWALAAVVAIVAVAALTTWLTAPRPGGHLDP
MSMEG_6218|M.smegmatis_MC2_155 -----MDAG---PMKIRNLRWIVPTAVVIVVLAVLTVYLTAPRPGGRMDP
TH_4091|M.thermoresistible__bu MSRPSTAVGPTLRERWRTARWVVLVVSVLAVVAVLGVLLSPPQSGGRMDP
MAB_0390c|M.abscessus_ATCC_199 -MTISTATSPRLRDRWRTLAWALAALVAIVITGLILS--KPPRPEGYLDP
: .
Mb3716|M.bovis_AF2122/97 ASTSSTGGHALATLLGNHGVEVVVADSIADVEAAARPDSLLLVAQTQYLV
Rv3691|M.tuberculosis_H37Rv ASTSSTGGHALATLLGNHGVEVVVADSIADVEAAARPDSLLLVAQTQYLV
MMAR_5201|M.marinum_M ESTSGSGARALVTLLREGGVEVVVANTVADVENAARADTLLLVAQTQYLA
MUL_4274|M.ulcerans_Agy99 ESTSGSGARALVTLLREGGVEVVVANTVAGVENAARADTLLLVAQTQYLA
MAV_0413|M.avium_104 ASTDPDGAHALVALLRDGGVDVVVADHIADVESAARPDALILVAQSQYLA
Mflv_1338|M.gilvum_PYR-GCK ASTSPDGTHALVTLLRDRGVTVVEAASISDVEDAAGENTLVVAAQTYHLF
Mvan_5454|M.vanbaalenii_PYR-1 TSTSSDGVLALMTLLREHGVTVVEAASIADVEREAREDTLVVAAQTYHLY
MSMEG_6218|M.smegmatis_MC2_155 DSTSPEGARALVTLLRDHGVDVITATGIDDVERDARPGTLLVAAQTLFLS
TH_4091|M.thermoresistible__bu EATTPEGAHALVTLLDEQGVEVVTAGTVDEVVDAARPDTLLVLAQLFYL-
MAB_0390c|M.abscessus_ATCC_199 DAVTQRGGHALAQLLRDHGVTVTRATTIGEVRAAMRPDGQLMVLDNGYLS
:. * ** ** : ** * * : * . :: : .*
Mb3716|M.bovis_AF2122/97 DNALLDRLAKAPGDLLLVAPTSRTRTALTPQLRIAAASPFNS-QPNCTLR
Rv3691|M.tuberculosis_H37Rv DNALLDRLAKAPGDLLLVAPTSRTRTALTPQLRIAAASPFNS-QPNCTLR
MMAR_5201|M.marinum_M NNALLNRLSRVPGDLLLVEPTARTRRVLTPKLRVGAAETLAI-RPDCPLR
MUL_4274|M.ulcerans_Agy99 NNALLNRLSRVPGDLLLVEPTARTRRVLTPKLRVGAAETLAI-RPDCPLR
MAV_0413|M.avium_104 D-SVLDRLARIRSDLLLVEPTTEARKALLPGVRISGTNGFDS-DPNCTLR
Mflv_1338|M.gilvum_PYR-GCK DDELLQRLSEVPGDRLLIAPIGRTREALAPRLRRTDAAEFAGLDPGCDLR
Mvan_5454|M.vanbaalenii_PYR-1 DDDQLRRLAAAPGDRLLIAPIGKTREELAPELRRAETTEFGGLAPDCDLR
MSMEG_6218|M.smegmatis_MC2_155 GDDQLERLSQVPGDLLLVEPTTKTREKLAPAIRPDDAAAFGGGEPDCDLP
TH_4091|M.thermoresistible__bu DEDQLRRLDGLPGDRLLIAPSARAREILAPQIRTDGLLTFGG-TPDCDMR
MAB_0390c|M.abscessus_ATCC_199 D-NILDSLAELPGDRLMLAPYSDTRERLAAQVRIRSYQDDELVEPGCDLR
. * * .* *:: * :* * . :* *.* :
Mb3716|M.bovis_AF2122/97 EANRAGSVQ--WGPSDTYQATGD--LVLTSCYGGALVRFRAEGRTITVVG
Rv3691|M.tuberculosis_H37Rv EANRAGSVQ--WGPSDTYQATGD--LVLTSCYGGALVRFRAEGRTITVVG
MMAR_5201|M.marinum_M EADRAGTVR--FGPSDAYRGKGE--LAMISCYGGALVRYQDVGRTVTVVG
MUL_4274|M.ulcerans_Agy99 EADRAGTVR--FGPSDAYRGKGE--LAMISCYGGALVRYQDIGRTVTVVG
MAV_0413|M.avium_104 EAVRAGSVR--FGRATTFESEDG--RAMTRCYDGALIRFRDGGRAITAVG
Mflv_1338|M.gilvum_PYR-GCK EATRAGTVQ--LGAADTFEADES--ADVTSCYDGALVRYTEGGRTVTVVG
Mvan_5454|M.vanbaalenii_PYR-1 EANRAGTVQ--FGIAETYEAQGS--TAVTRCYDGVLARYTDDGRTITVVG
MSMEG_6218|M.smegmatis_MC2_155 EARRAGETQ--LGLSNTFRAAGD--IPVQRCYDGAVVRYRDGNRTVTVVG
TH_4091|M.thermoresistible__bu EATRAGDVN--FGIAETFTAADDSDVDLTRCYDGAVVRFTDGDRVTTVVG
MAB_0390c|M.abscessus_ATCC_199 EARQAGAIQTYLGPEYTFTDPGP---GRISCYGGTLLRYRDGDRTITVLG
** :** . * :: **.*.: *: .*. *.:*
Mb3716|M.bovis_AF2122/97 SSNFMTNGGLLPAGNAALAMNLAGNRPRLVWYAPDHIEG-EMSSPSSLSD
Rv3691|M.tuberculosis_H37Rv SSNFMTNGGLLPAGNAALAMNLAGNRPRLVWYAPDHIEG-EMSSPSSLSD
MMAR_5201|M.marinum_M SNHFMTNDGLLEQGNAALAMNLAGARPRLIWYAPHLVEG-ATSSPSSLSD
MUL_4274|M.ulcerans_Agy99 SNHFMTNDGLLEQGNAALAMNLAGARPRLIWYAPHLVEG-ETSSPSSLSD
MAV_0413|M.avium_104 STDFMTNGSLLQAGNAALAMNLAGGRPRLIWYAPHFVEG-ESSSKATVLD
Mflv_1338|M.gilvum_PYR-GCK SDEFVLNSGLLHEGNAALAMNLAGSQPRMIWYAPQFNEGDGSAGDAPFTD
Mvan_5454|M.vanbaalenii_PYR-1 SEQFLMNAGLAEEGNAALAMNLAGTHPRMIWYAPQRSEGGESGGAASLTD
MSMEG_6218|M.smegmatis_MC2_155 TAEFMSNSGLLKEGNAALAMNLAGDRDRVIWYSPQKFEG-TSTGDRKLSD
TH_4091|M.thermoresistible__bu SSGFMSNGALADGGNAALALNLAGTQPRVVWFAPQ-QPPAESTGDAALSD
MAB_0390c|M.abscessus_ATCC_199 DDTLLSNKQLDKQGNAALAMNLAGRSAHLVWYVPERPKVGASAKPKSMGD
:: * * ******:**** :::*: *. . *
Mb3716|M.bovis_AF2122/97 LIPENVHWTIWQLWLVVLLVALWKGRRIGPLVAEELPVVIRASETVEGRG
Rv3691|M.tuberculosis_H37Rv LIPENVHWTIWQLWLVVLLVALWKGRRIGPLVAEELPVVIRASETVEGRG
MMAR_5201|M.marinum_M LIPANVSWIVWQLWLAVILVALWKGRRMGPLVAEEMPVVVRASETVEGRG
MUL_4274|M.ulcerans_Agy99 LIPANVSWIVWQLWLAVILVALWKGRRMGPLVAEEMPVVVRASETVEGRG
MAV_0413|M.avium_104 LIPANVYWVVGQLAVVVLLVAVWRGRRPGPLVAEELPVVVRASETVEGRG
Mflv_1338|M.gilvum_PYR-GCK LIPPQVYWMVLQLALAVALLAWWRGRRVGPLVAEQLPVVVRASETVEGRG
Mvan_5454|M.vanbaalenii_PYR-1 LIPAQVYWMVLQLILAVALLAWWKGRRVGPLVAEALPVVVRASETAEGRG
MSMEG_6218|M.smegmatis_MC2_155 LMPDQVRWIVLQLCVVVALFALWQARRLGPLVAESLPVVVRASETVEGRG
TH_4091|M.thermoresistible__bu LIPEHVGWIVWQLIVVVVLLAWWQGRRLGPLVTEPLPVVVRASETVEGRG
MAB_0390c|M.abscessus_ATCC_199 LIPDQVNMAIWQLCIVVLLLAIWRGRRLGPVIAEKLPVIVRASETTEGRG
*:* :* : ** :.* *.* *:.** **:::* :**::*****.****
Mb3716|M.bovis_AF2122/97 RLYRSRRARDRAADALRTATLQRLRPRLGVGAGAPAPAVVTTIAQRSKAD
Rv3691|M.tuberculosis_H37Rv RLYRSRRARDRAADALRTATLQRLRPRLGVGAGAPAPAVVTTIAQRSKAD
MMAR_5201|M.marinum_M RLYRSRRARDRAADALRTATLQRLLPRLGIGSSADPQAVAITVAQRSGSD
MUL_4274|M.ulcerans_Agy99 RLYRSRRARDRAADALRTATLQRLLPRLGIGSSADPQAVAITVAQRSGAD
MAV_0413|M.avium_104 RLYRSRRARDRAAAALRTAALQRLTPKLGLAGGATPEAVVSTAAQRTGSD
Mflv_1338|M.gilvum_PYR-GCK RLYRSRRARDVAAEFLRTAARHRMLPRLGLNYAAPPPAVIQAVADRCGLD
Mvan_5454|M.vanbaalenii_PYR-1 RLYRSRRARDVAAESLRTATRQRMLPRLGLTPGAPPEAVSQAVAARCGLD
MSMEG_6218|M.smegmatis_MC2_155 KLYRSHRARDRAADALRTATLQRLLPRLGLTAQADQAAVAAAVAVRCGQD
TH_4091|M.thermoresistible__bu RLYRSRRARDRAAEALRTGAVQRLVSRLGLQTSATPSEVTLAVAARSGRD
MAB_0390c|M.abscessus_ATCC_199 RLYRSRRARDLASESLREAATYRIVRRLGLPVDGAPQVVTATIAQRIGRD
:****:**** *: ** .: *: :**: . * : * * *
Mb3716|M.bovis_AF2122/97 PPFVAYHLFGPAPATDNDLLQLARALDDIERQVTHS
Rv3691|M.tuberculosis_H37Rv PPFVAYHLFGPAPATDNDLLQLARALDDIERQVTHS
MMAR_5201|M.marinum_M AGYVWYHLFGPPPADDHDLLQLARALDDIERQVTHS
MUL_4274|M.ulcerans_Agy99 AGYVWYHLFGPPPADDHDLLQLARALDDIERQVTHS
MAV_0413|M.avium_104 PGWVSYHLFGPPPTTDHDLLQLARALDDIERQVAHP
Mflv_1338|M.gilvum_PYR-GCK SAALAHTLYGPPPATDADLVNLARELDDIERQVAQS
Mvan_5454|M.vanbaalenii_PYR-1 PQTVAHTLYGQPPDTDADLVTLARALDDIERQVAQS
MSMEG_6218|M.smegmatis_MC2_155 SQTVGYTLFGPPPGTDDELVHLAHRLDDIERQVAHS
TH_4091|M.thermoresistible__bu PAAVNHVLYGPVPATDADLVTLAHELDDIERQVAQS
MAB_0390c|M.abscessus_ATCC_199 PTEVHHVLFGPAPSDDQQLTNLTQQLDVLERQVRES
. : : *:* * * :* *:: ** :**** ..