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M. smegmatis MC2 155 MSMEG_5432 (pth)

annotation: peptidyl-tRNA hydrolase
coordinates: 5514818 - 5515393
length: 191

MAEPLLVVGLGNPGPTYAKTRHNLGFMVADVLAGRIGSAFKVHKKSGAEVVTGRLAGTSVVLAKPRCYMN
ESGRQVGPLAKFYSVPPQQIVVIHDELDIDFGRIRLKLGGGEGGHNGLRSVASALGTKNFHRVRIGVGRP
PGRKDPAAFVLENFTAAERAEVPTIVEQAADATELLIAQGLEPAQNTVHAW
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5432pth-100% (191)peptidyl-tRNA hydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1042cpth1e-9182.20% (191) peptidyl-tRNA hydrolase
M. gilvum PYR-GCKMflv_1938-5e-8477.49% (191) peptidyl-tRNA hydrolase
M. tuberculosis H37RvRv1014cpth1e-9182.20% (191) peptidyl-tRNA hydrolase
M. leprae Br4923MLBr_00244pth8e-8275.00% (188) peptidyl-tRNA hydrolase
M. abscessus ATCC 19977MAB_1142c-2e-7671.43% (189) peptidyl-tRNA hydrolase (PTH)
M. marinum MMMAR_4473pth2e-9183.25% (191) peptidyl-tRNA hydrolase Pth
M. avium 104MAV_1151pth7e-9282.20% (191) peptidyl-tRNA hydrolase
M. thermoresistible (build 8)TH_0906pth1e-2279.66% (59) peptidyl-tRNA hydrolase
M. ulcerans Agy99MUL_4644pth3e-9283.77% (191) peptidyl-tRNA hydrolase
M. vanbaalenii PYR-1Mvan_4788-7e-8779.58% (191) peptidyl-tRNA hydrolase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1938|M.gilvum_PYR-GCK          ---MAEP--------VLVVGLGNPGPQYATTRHNIGFMVADVLADRMGET
Mvan_4788|M.vanbaalenii_PYR-1       ---MAEP--------VLVVGLGNPGPQYATTRHNAGFMVVDILADRMGEK
Mb1042c|M.bovis_AF2122/97           ---MAEP--------LLVVGLGNPGANYARTRHNLGFVVADLLAARLGAK
Rv1014c|M.tuberculosis_H37Rv        ---MAEP--------LLVVGLGNPGANYARTRHNLGFVVADLLAARLGAK
MAV_1151|M.avium_104                ---MAEP--------LLVVGLGNPGDNYARTRHNVGFMVADLLAARMGSK
MMAR_4473|M.marinum_M               ---MAEP--------LLVVGLGNPGENYARTRHNLGFMVADLLAARLGAK
MUL_4644|M.ulcerans_Agy99           ---MAEP--------LLVVGLGNPGENYARTRHNLGFMVADLLAARLGAK
MLBr_00244|M.leprae_Br4923          ---MAEPTLASGWYPRLVVGLGNPGKNYGRTRHNVGFMVANLLAVRLGSK
MSMEG_5432|M.smegmatis_MC2_155      ---MAEP--------LLVVGLGNPGPTYAKTRHNLGFMVADVLAGRIGSA
MAB_1142c|M.abscessus_ATCC_199      MPVLSDD-------AVLVVGLGNPGPNYAKTRHNLGFMVADLLAAKDGAT
TH_0906|M.thermoresistible__bu      ---MSEPQPAAG--PRLIVGLGNPGPRYAGTRHNLGFMVADILAGRMGEK
                                       :::          *:*******  *. **** **:*.::** : *  

Mflv_1938|M.gilvum_PYR-GCK          FKVHKKSGAEVTTGRLAGRPVVLAKPRVYMNESGRQVGPLAKFYSIAPTD
Mvan_4788|M.vanbaalenii_PYR-1       FKVHKKSGAEVATGRLAGRPVVLAKPRVYMNESGRQVGPLAKFYSVAPAD
Mb1042c|M.bovis_AF2122/97           FKAHKRSGAEVATGRSAGRSLVLAKPRCYMNESGRQIGPLAKFYSVAPAN
Rv1014c|M.tuberculosis_H37Rv        FKAHKRSGAEVATGRSAGRSLVLAKPRCYMNESGRQIGPLAKFYSVAPAN
MAV_1151|M.avium_104                FKAHKRSGAEIVSGRLAGRSVVVAKPRCYMNESGRQVGPLAKFYSVPPGD
MMAR_4473|M.marinum_M               FKVHKRSGAEVVTGRLAQRSVVLAKPRCYMNESGRQVAPLAKFYSVPPAD
MUL_4644|M.ulcerans_Agy99           FKVHKRSGAEVVTGRLAQRSVVLAKPRCYMNESGRQVAPLAKFYSVPPAD
MLBr_00244|M.leprae_Br4923          FEVHKRSGADVVNGRLAGCSMLVAKPRNYMNESGQQVGLLAKLYSVTPAD
MSMEG_5432|M.smegmatis_MC2_155      FKVHKKSGAEVVTGRLAGTSVVLAKPRCYMNESGRQVGPLAKFYSVPPQQ
MAB_1142c|M.abscessus_ATCC_199      FKPHKKSGAEATTIRLGGRAVNLAKPRTFMNTSGPQVAALAKFFSVPPAN
TH_0906|M.thermoresistible__bu      FKVHKKSGAEVITGRLAGRPVXX---------------------------
                                    *: **:***:  . * .  .:                             

Mflv_1938|M.gilvum_PYR-GCK          VVIIHDELDIDFGRIRLKAGGGVAGHNGLRSVGSALSTNDFQRVRVGIGR
Mvan_4788|M.vanbaalenii_PYR-1       VVIVHDELDIDFGRIRLKAGGGVAGHNGLRSVASALGGNDFQRVRVGIGR
Mb1042c|M.bovis_AF2122/97           IIVIHDDLDLEFGRIRLKIGGGEGGHNGLRSVVAALGTKDFQRVRIGIGR
Rv1014c|M.tuberculosis_H37Rv        IIVIHDDLDLEFGRIRLKIGGGEGGHNGLRSVVAALGTKDFQRVRIGIGR
MAV_1151|M.avium_104                IIVIHDDLDLDFGRIRLKIGGGEGGHNGLRSVSNALGSKDFQRVRIGIGR
MMAR_4473|M.marinum_M               LIVIHDELDLDFGRIRLKFGGGEGGHNGLRSVAAALGTKDFQRVRIGIGR
MUL_4644|M.ulcerans_Agy99           LIVIHDELDLDFGRIRLKFGGGEGGHNGLRSVAAALGTKNFQRVRIGIGR
MLBr_00244|M.leprae_Br4923          IIIVHDDLDLDFGRIRLKLGGGEGGHNGLRSVAAALGTKDFQRVRIGIGR
MSMEG_5432|M.smegmatis_MC2_155      IVVIHDELDIDFGRIRLKLGGGEGGHNGLRSVASALGTKNFHRVRIGVGR
MAB_1142c|M.abscessus_ATCC_199      VIVMHDELDLDFGTVRLKLGGGEGGHNGLRSVSQSLGTKDYLRVRLGVGR
TH_0906|M.thermoresistible__bu      -------------------GGSPEQHPDL----------DLLRQRQ--AR
                                                       **.   * .*          :  * *   .*

Mflv_1938|M.gilvum_PYR-GCK          PPGQKSGASFVLEPFNSRERPELGTIIEQAADATELLIELGIEPAQNTVH
Mvan_4788|M.vanbaalenii_PYR-1       PPGHKSGASFVLENFNSVERKEVPTILEQAADATELLVAQGLEPAQNTVH
Mb1042c|M.bovis_AF2122/97           PPGRKDPAAFVLENFTPAERAEVPTICEQAADATELLIEQGMEPAQNRVH
Rv1014c|M.tuberculosis_H37Rv        PPGRKDPAAFVLENFTPAERAEVPTICEQAADATELLIEQGMEPAQNRVH
MAV_1151|M.avium_104                PPGRKDPAAFVLENFTSTERADVPTICEQAADATELLIELGLEPAQNRVH
MMAR_4473|M.marinum_M               PPGRKDPATFVLENFSSPERPEVPTICEQAADATELLVEIGLEPAQNRVH
MUL_4644|M.ulcerans_Agy99           PPGRKDPATFVLENFSSPERPEVPTICEQAADATELLVEVGLEPAQNRVH
MLBr_00244|M.leprae_Br4923          PTGRKDPASFVLENFTTAERMQVPTICKRAADATELLVGLGLEPAQNHVH
MSMEG_5432|M.smegmatis_MC2_155      PPGRKDPAAFVLENFTAAERAEVPTIVEQAADATELLIAQGLEPAQNTVH
MAB_1142c|M.abscessus_ATCC_199      PPGRKDPAAFVLENFAKAETDQVPLLCEQGADAAELLIRLGLEAAQNQVH
TH_0906|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_1938|M.gilvum_PYR-GCK          AWS
Mvan_4788|M.vanbaalenii_PYR-1       AWG
Mb1042c|M.bovis_AF2122/97           AW-
Rv1014c|M.tuberculosis_H37Rv        AW-
MAV_1151|M.avium_104                AW-
MMAR_4473|M.marinum_M               AW-
MUL_4644|M.ulcerans_Agy99           AW-
MLBr_00244|M.leprae_Br4923          AW-
MSMEG_5432|M.smegmatis_MC2_155      AW-
MAB_1142c|M.abscessus_ATCC_199      AWG
TH_0906|M.thermoresistible__bu      ---