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RSLEDVAAEVFGWRSLRAEQLKAMSAILDGSDVLAVMPTGSGKSAIYQVPAVLLSGPVLVISPLIALQFD QIAQLKRTDAPQAVAINSRQSAAKLNRAWDAVRGGQARYIFLGPEQLARDEVMDRLAEVQPALVVVDEAH CVSAWGHDFRPTYLGSSHLIGVWCCPTLCRVGD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5399 | - | - | 100% (174) | ATP-dependent DNA helicase RecQ |
| M. smegmatis MC2 155 | MSMEG_5935 | - | 1e-18 | 39.47% (152) | ATP-dependent DNA helicase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1524 | - | 5e-21 | 42.86% (147) | ATP-dependent DNA helicase RecQ |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_4431 | - | 5e-27 | 43.23% (155) | PUTATIVE putative helicase c2 |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5233 | - | 5e-20 | 42.18% (147) | ATP-dependent DNA helicase RecQ |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu MSSTNRPLPPAAEASYRILAEHGPLAASELRERIRPQGFALPVERLQQLS
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu DRFPHRFHTTPDGLLTIATATSENEPDQPETRSDDENWYRPQPDRPEPGR
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu IAVLDIETTGLNRTHDFITEVALVRLDGTPLLDLTVQLPDGVPRPAMARS
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu EPIPVGDAIAALSRQLENVDLVVGHNLLGFDLPFLETAARRAGIPALDLR
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu SAADSIHLSLLVDVALPNRQLADLLLHYQLSNDEPHRALADATATAAAIR
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu KMLAAVDMAETSWQLAIAALETFNHPLVKLFPPLTEPPDLSALSRPTDPL
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu LTATGSPAPDARSAARNDFPVLHQKRGLHPRPQQQEMAHAVGAVFDHGGR
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu LAVEAPTGTGKSLAYLLPALGRASQAGRPVIVATATKALQNQLRADATRL
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu HDDGLLRAPFRQLQGVGNYVCARELEGVLSDADASGLAIAVAIRALASSP
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu SGTWDDVTDFTLRNSDARYAQTRGRLRTSSGGCDRRNCAWASLCPLMQQL
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu RGLDKTPGVVSVNHALIASWIKLEQQGIPAPGDVLAQGRADLVFDEAHAL
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu EDSLTAAWTEQIDALELEILVNSLARRSRLIRDIRKRASGNPETEEAIQA
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu ITTASGQVRSTGQELTDAIVTYLHEYAGQSDGVVLQSGVVDNRPEFRTLR
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu QAASAVRYSLIQLAKAVKALRNSLYEVDGLKSALQRLRGYAERLNNAIDL
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu LETVGTLPDTHRWVYRLAAEEDDPAAWVYERLPIHVFPEFKQHVVDHTHS
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu TVLCSATLTVEHRFDYLASRLGIRIEEDPADDDAFRALRLHSPFDYQNQS
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu LVVLTNHLPVPVPVNEREFCEEMAADQAGFLSLSGGKTLTLFASRRRMEA
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu VAEGVRTKKDELAARGVELLVQGELGRSQIAHRFKTEPGTVLYGLKSYWE
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu GFDAPGETLSYLFLEKPPYPHPDDPLVSARSRAIAEWGGDPFRDYVLPMT
Mflv_1524|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu AMLFTQGFGRLIRSENDRGAALVCDRRLHSPTQAQHVILNSLPGPAIYEA
Mflv_1524|M.gilvum_PYR-GCK -------------------------------MGLMNDSPAVAKATATRAD
Mvan_5233|M.vanbaalenii_PYR-1 --------------------------------------------MTTRAD
MSMEG_5399|M.smegmatis_MC2_155 -----------------------------------------------MRS
TH_4431|M.thermoresistible__bu IDRDDAWTRAIEFVTGEPPDLSNAISFGRDDVSQLLEELRLVEGEDPTAK
.
Mflv_1524|M.gilvum_PYR-GCK AQAILEQLAGPDAVLRDDQWTAIEALVVHRRRALVVQRTGWGKSAVYFIS
Mvan_5233|M.vanbaalenii_PYR-1 AQAILEQLAGPGAVLRDDQWTAIEALVVHRRRALVVQRTGWGKSAVYFIS
MSMEG_5399|M.smegmatis_MC2_155 LEDVAAEVFG-WRSLRAEQLKAMSAILDGSD-VLAVMPTGSGKSAIYQVP
TH_4431|M.thermoresistible__bu LTEAAEKLFG-ITKLHPKQLDVMRAIIDGKD-VVAVLPTGFGKSICFQLP
:: * *: .* .: *:: .:.* ** *** : :.
Mflv_1524|M.gilvum_PYR-GCK AKLLRAAGHGPTVIVSPLLALMRNQVAAAE---RAGVHAATINSSNVTDW
Mvan_5233|M.vanbaalenii_PYR-1 AKLLRAAGHGPTVIVSPLLALMRNQVAAAD---RAGVHAATINSSNVTDW
MSMEG_5399|M.smegmatis_MC2_155 AVLLSG----PVLVISPLIALQFDQIAQLK-RTDAPQAVAINSRQSAAKL
TH_4431|M.thermoresistible__bu ALLAPQD--RATVVVSPLIALIKDQVNDLRGRRGIRPVHGITGTTSRVVQ
* * ..:::***:** :*: . . . .
Mflv_1524|M.gilvum_PYR-GCK SDIHDRVRRGELDVLLVSPERLNNPDFRDEVLPALADDAGLVVVDEAHCV
Mvan_5233|M.vanbaalenii_PYR-1 AEIHDRVRSGDLDVLLVSPERLNNPDFRDQVLPSLAHDAGLVVVDEAHCV
MSMEG_5399|M.smegmatis_MC2_155 NRAWDAVRGGQARYIFLGPEQLARDEVMD-RLAEVQ--PALVVVDEAHCV
TH_4431|M.thermoresistible__bu TEILRDTANGQVRLLYVSPERLARDPVLRGALGRQQ--LNRVVVDEAHCI
. *: : :.**:* . . * ********:
Mflv_1524|M.gilvum_PYR-GCK SDWGHDFRPDYRRIRTLIADLGADVPVLATTATANDRVVADVAAQ---LG
Mvan_5233|M.vanbaalenii_PYR-1 SDWGHDFRPDYRRIRTLLADLGADVPVLATTATANDRVVADVAAQ---LG
MSMEG_5399|M.smegmatis_MC2_155 SAWGHDFRPTY---------------------------------------
TH_4431|M.thermoresistible__bu SVWGHDFRPEFRQVPASVASFDTRPPRAGLTATATPEVEHDITHAMEMV-
* ******* :
Mflv_1524|M.gilvum_PYR-GCK VG--GPESE---HDTLVLRGGLDRESLRLSVVKAGNPAQRAAWLVSQLG-
Mvan_5233|M.vanbaalenii_PYR-1 VGDFGREDQDGGSDTLVLRGGLDRESLRLSVVNAGNPAQRAAWLVAQLD-
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu -------------DPTSIREPSDRPNLRLRVIKRADERDRARELLRFVTW
Mflv_1524|M.gilvum_PYR-GCK SLPGSGIVYTLTVAQANDVAALLAEHGHKVASYTGATEAAEREQLEGDLL
Mvan_5233|M.vanbaalenii_PYR-1 SLPGSGIVYTLTVAQAHDVASLLAEQGHKVAAYTGATEASEREQLESDLL
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu AADQPGIVYVSKRALAEEIAALLRRAGHAARAYHAGMVPEQRDAVQEDFD
Mflv_1524|M.gilvum_PYR-GCK ANRVKALIATSALGMGFDKPDLGFVVHLGAPSSPIAYYQQVGRAGRSTDS
Mvan_5233|M.vanbaalenii_PYR-1 DNRVKALIATSALGMGFDKPDLGFVVHLGAPSSPIAYYQQVGRAGRSTAS
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu SDTTRIIVATKAFGMGINKPNIGWVVHYDLPDSLDGYAQESGRAARSRDL
Mflv_1524|M.gilvum_PYR-GCK AEVVLLPGHEDQDVWRYFASVAFPSEAMVRNVIDALESDRAQSTAALEPL
Mvan_5233|M.vanbaalenii_PYR-1 AEVILLPGREDQEVWRYFASVAFPSESMVRNVIGALETDRPQSTAALEPL
MSMEG_5399|M.smegmatis_MC2_155 ------------------------------LGSSHLIGVWCCP--TLCRV
TH_4431|M.thermoresistible__bu TGECLLLYTDADIARRRRLIDAHSTKADADITQQLLTTLWSCPERSDYRV
* . : :
Mflv_1524|M.gilvum_PYR-GCK VDLGRSRLEMVLKVLDVDGAVRRVKGG-WISTGQPWSYDEPRYRTLDEAR
Mvan_5233|M.vanbaalenii_PYR-1 VDLNRSRLEMVLKVLDVDGAVRRVKGG-WVATGRPWAYDEQRYRTLDEAR
MSMEG_5399|M.smegmatis_MC2_155 GD------------------------------------------------
TH_4431|M.thermoresistible__bu FDIDEIADELGIDDDELNVHLAQLERVRAIKQGLDCSARGTVDVGFREPE
*
Mflv_1524|M.gilvum_PYR-GCK RREQQAMLDYQSTAECRMVFLRRQLDDPGLRDGERCGRCDNCVGSRYESG
Mvan_5233|M.vanbaalenii_PYR-1 RREQQAMLDYQSTDGCRMAFLRRQLDDPELGADERCGRCDNCAGSSYSAD
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu DENERRLYRELFYKDHRARPNVRIQLDFQQLKDERGYDPDELEQQLINWS
Mflv_1524|M.gilvum_PYR-GCK VDAAVAEDSRQRLMRPG--VVLAPRKQWPTGLAKLGIDLSGKITDGPAPG
Mvan_5233|M.vanbaalenii_PYR-1 VDAAVAEDSRQRLMRPG--VEISPRKQWPSGLAKLGVDLSGRITDGPAPG
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu LDRLITFSSSRRLRRVQLLTRVAPRDALEGESARWKWWQKRRLQAMIDYA
Mflv_1524|M.gilvum_PYR-GCK RVIGRLTDLGWGARLRRLLDAEDAEAPEEVVQAAVKVLASWDWETRPSAV
Mvan_5233|M.vanbaalenii_PYR-1 RVIGRLTDLGWGARLRTLLEQDDAEVPDDVVQAAVKVLAAWDWQVRPTAV
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu TDDTRCRRTVIGDHFGDAVEDCKSRDVELCDVCSGEPAPWSAIPDHKVAD
Mflv_1524|M.gilvum_PYR-GCK MAVDSDTHPQLISSLARRLSELGRLTDLGVLRYTPDRRPVTASNSAYRVA
Mvan_5233|M.vanbaalenii_PYR-1 MALDSDTHPLLTSSLARRLAELGRLTDLGVLRYTPERRPVTAANSAYRVA
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu PELLVNAELTALQAIAWASAFRRGAYGEASLKAAVLGRESLGDNRPLGAG
Mflv_1524|M.gilvum_PYR-GCK ALHGAFSAPDPALMAQVGGPVLLVDDLADSGWTITMAARVVRAAGAVQVL
Mvan_5233|M.vanbaalenii_PYR-1 ALRGAWESPDPDAISAAGGPVLLVDAMTDTGWTLTMAARVVRSAGAPAVL
MSMEG_5399|M.smegmatis_MC2_155 --------------------------------------------------
TH_4431|M.thermoresistible__bu VLNCPQFGALRHVRNGEKRWDQAVDKLIGQGLVERRTVVRESTQMPYQSL
Mflv_1524|M.gilvum_PYR-GCK PFAVAATA--------
Mvan_5233|M.vanbaalenii_PYR-1 PFALAATS--------
MSMEG_5399|M.smegmatis_MC2_155 ----------------
TH_4431|M.thermoresistible__bu ALTPLGEQTLGIPEPQ