For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_5280 (-)

annotation: cysteine dioxygenase type I superfamily protein
coordinates: 5372158 - 5372706
length: 182

LTTVSSGSAALGTSATVPAVSAPTRLRLPDLLNTTDRAADAVLSGRYDRLLRDLPEDERWYTRLDGNDEL
DVWLISWVPDRSTELHDHGGSLGALTVVSGALTETRWDGEALRHRRLSAGSQAAFPLGWVHDVVRAPGPV
IGPTLSVHAYSPPLTAMSYYEVTQQNTLRRSRTELTDAPEG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5280--100% (182)cysteine dioxygenase type I superfamily protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1094-1e-6565.93% (182) hypothetical protein Mb1094
M. gilvum PYR-GCKMflv_2033-2e-6473.81% (168) cysteine dioxygenase type I
M. tuberculosis H37RvRv1065-1e-6565.93% (182) hypothetical protein Rv1065
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1182-3e-6472.25% (173) hypothetical protein MAB_1182
M. marinum MMMAR_4401-2e-6170.37% (162) hypothetical protein MMAR_4401
M. avium 104MAV_1192-3e-6468.97% (174) cysteine dioxygenase type I superfamily protein
M. thermoresistible (build 8)TH_0677-7e-7178.40% (162) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_0216-3e-6567.03% (185) hypothetical protein MUL_0216
M. vanbaalenii PYR-1Mvan_4684-8e-6676.51% (166) cysteine dioxygenase type I

CLUSTAL 2.0.9 multiple sequence alignment


Mb1094|M.bovis_AF2122/97            -MVMPLVT------PTTAVPSPGPTRLRVADLLRATDQAADDVLGGRCDH
Rv1065|M.tuberculosis_H37Rv         -MVMPLVT------PTTAVPSPGPTRLRVADLLRATDQAADDVLGGRCDH
MAV_1192|M.avium_104                -MPVPAATLAALRPPFPSSPSPGPTRLRVPDLLYATDQAADDVLSGRCDH
MMAR_4401|M.marinum_M               ----------------------------MPDLLHATDQVADDVLSGRCDH
MUL_0216|M.ulcerans_Agy99           -MPLRQSSVTSSRPQTVTSPAPGPTRLRVPDLLHATDQVADDVLSGRCDH
TH_0677|M.thermoresistible__bu      -MVSTRTG---------VLSGVAPTRLRLPDLLHTTDRLADDVLSGRYDH
MAB_1182|M.abscessus_ATCC_1997      -MTTASVLDLR----RPSSAGSLPTRLRLPDLLRITDEGADDALHGRFDH
Mflv_2033|M.gilvum_PYR-GCK          -------------------MALAPTRLRPADLLHVTDRFADDILGGDYDH
Mvan_4684|M.vanbaalenii_PYR-1       -------------------MTLAPTRLRPADLLHVTDRFADDVLGGDYDH
MSMEG_5280|M.smegmatis_MC2_155      MLTTVSSGSAALGTSATVPAVSAPTRLRLPDLLNTTDRAADAVLSGRYDR
                                                                 .***  **. **  * *  *:

Mb1094|M.bovis_AF2122/97            LLPDGGVPQTQRWYTRIHGDEELDIWLISWVPGQPTELHDHGGSLGALTV
Rv1065|M.tuberculosis_H37Rv         LLPDGGVPQTQRWYTRIHGDEELDIWLISWVPGQPTELHDHGGSLGALTV
MAV_1192|M.avium_104                LLPPGGIPASRRWFTRIHGDEELDVWLISWVPGHPTELHDHGGSLGALTV
MMAR_4401|M.marinum_M               LLPEGGVPDDGRWFTRVHGDDELDVWLISWVPGHATELHDHGGSLGALTV
MUL_0216|M.ulcerans_Agy99           LLPEGGVPDDGRWFTRVHGDDELDVWLISWVPGHATELHDHGGSLGALTV
TH_0677|M.thermoresistible__bu      LLPAAGLPRHERWYTRLVSDDELDVWLISWVPERATELHDHGGSLGALTV
MAB_1182|M.abscessus_ATCC_1997      LLPAGGLPVDERWATRIHADDELDVWLISWVPDKSTELHDHCGSLGALTV
Mflv_2033|M.gilvum_PYR-GCK          VLPAGGPPTTERWFTRLHGNEELDVWLISWVPDCSTELHDHGGSLGALTV
Mvan_4684|M.vanbaalenii_PYR-1       VLPAAGLPTAERWFTRLHGTDELDVWLISWVSNRSTELHDHGGSLGALTV
MSMEG_5280|M.smegmatis_MC2_155      LLRD--LPEDERWYTRLDGNDELDVWLISWVPDRSTELHDHGGSLGALTV
                                    :*     *   ** **: . :***:******.  .****** ********

Mb1094|M.bovis_AF2122/97            LSGSLNEYRWDGRRLRRRRLDAGDQAGFPLGWVHDVVWAPRPIGGPD---
Rv1065|M.tuberculosis_H37Rv         LSGSLNEYRWDGRRLRRRRLDAGDQAGFPLGWVHDVVWAPRPIGGPD---
MAV_1192|M.avium_104                VSGSLNEYRWDGRALRRRRLDAGDQAGFPLGWVHDVVWAPRPVSGPVSRR
MMAR_4401|M.marinum_M               LSGSLNEFRWDGTRLRRRRLDAGDQAGFPLGWVHDVVWAPRPAAEPI---
MUL_0216|M.ulcerans_Agy99           LSGSLNEFRWDGTRLRRRRLDAGDQAGFPLGWVHDVVWAPRPAAEPI---
TH_0677|M.thermoresistible__bu      LSGSLAETRWDGGTLRRRRLDAGDQAGFPLGWVHDVVWAP----------
MAB_1182|M.abscessus_ATCC_1997      LSGSLHEYRWDGSQLVRRRLDAGDQAGFPLGWVHDVMRAPLKLSGAP---
Mflv_2033|M.gilvum_PYR-GCK          VSGALRETRWDGSALRDRRLVAGDQAAFPLGWVHDVVWARDGVTVG----
Mvan_4684|M.vanbaalenii_PYR-1       VSGTLRETRWDGEALRERRLVAGDQAAFPLGWVHDVVWARESIRGG----
MSMEG_5280|M.smegmatis_MC2_155      VSGALTETRWDGEALRHRRLSAGSQAAFPLGWVHDVVRAP----------
                                    :**:* * ****  *  *** **.**.*********: *           

Mb1094|M.bovis_AF2122/97            -AAGMAVAPTLSVHAYSPPLTAMSYYEITERNTLRRQRTELTDQPEGSG-
Rv1065|M.tuberculosis_H37Rv         -AAGMAVAPTLSVHAYSPPLTAMSYYEITERNTLRRQRTELTDQPEGSG-
MAV_1192|M.avium_104                AVAAAQAAPTLSVHAYSPPLTAMSYYDITERKTLRRQRTELTDQPEGS--
MMAR_4401|M.marinum_M               ---AAPLPPTLSVHAYSPPLTAMSYYEVTDHNTLRRKRTELTDHPEKP--
MUL_0216|M.ulcerans_Agy99           ---AAPLPPTLSVHAYSPPLTAMSYYEVTDRNTLRRKRTELTDHPEKP--
TH_0677|M.thermoresistible__bu      ---ATTTGPTLSVHAYSPPLAAMSYYEVTERNILRRKRTELTDGPEG---
MAB_1182|M.abscessus_ATCC_1997      --VPAESGPTLSVHAYSPPLTAMSYYEVTQANTLRRSRTILTDEPEGPAA
Mflv_2033|M.gilvum_PYR-GCK          ---GIAPAPTLSVHAYSPPLTAMSYYDVTDRNTLRRKRTQLTDKPEGD--
Mvan_4684|M.vanbaalenii_PYR-1       ---G-TPGPTLSVHAYSPPLTAMSYYEVTTQNTLRRNRTELTDKPESD--
MSMEG_5280|M.smegmatis_MC2_155      ---GPVIGPTLSVHAYSPPLTAMSYYEVTQQNTLRRSRTELTDAPEG---
                                            ************:*****::*  : ***.** *** **