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M. smegmatis MC2 155 MSMEG_5136 (-)

annotation: helix-hairpin-helix DNA-binding motif-containing protein
coordinates: 5237353 - 5237805
length: 150

PKGQELDVLSRRQCLDLLQRVRVGRLVFTEDALPAVQPVNFRLSHDDVIIRVAGGGKLSAAAKNQVVAFE
ADELDPDLRTGWSVTVVGHAEPITDIDQLVEVAGTFVQPWVDGKRDHFVRIRTERITGRQIRERGVPHYQ
GAEAQTSTP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5136--100% (150)helix-hairpin-helix DNA-binding motif-containing protein
M. smegmatis MC2 155MSMEG_5243-4e-2040.00% (130) helix-hairpin-helix DNA-binding motif-containing protein
M. smegmatis MC2 155MSMEG_6368-1e-1234.68% (124) DNA-binding protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0083-2e-1940.60% (133) hypothetical protein Mb0083
M. gilvum PYR-GCKMflv_1183-3e-1737.70% (122) hypothetical protein Mflv_1183
M. tuberculosis H37RvRv0080-1e-1840.60% (133) hypothetical protein Rv0080
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1041-3e-1635.38% (130) hypothetical protein MAB_1041
M. marinum MMMAR_1549-9e-1938.06% (134) hypothetical protein MMAR_1549
M. avium 104MAV_4110-1e-1735.43% (127) pyridoxamine 5'-phosphate oxidase family protein
M. thermoresistible (build 8)TH_3638-4e-1836.92% (130) PUTATIVE pyridoxamine 5'-phosphate oxidase-related, FMN-binding
M. ulcerans Agy99MUL_3483-3e-1837.31% (134) hypothetical protein MUL_3483
M. vanbaalenii PYR-1Mvan_0633-2e-1837.98% (129) pyridoxamine 5'-phosphate oxidase-related, FMN-binding

CLUSTAL 2.0.9 multiple sequence alignment


Mb0083|M.bovis_AF2122/97            MSPGSRRASPQSAREVVELDRDEAMRLLASVDHGRVVFTRAALPAIRPVN
Rv0080|M.tuberculosis_H37Rv         MSPGSRRASPQSAREVVELDRDEAMRLLASVDHGRVVFTRAALPAIRPVN
MSMEG_5136|M.smegmatis_MC2_155      MPKG---------QELDVLSRRQCLDLLQRVRVGRLVFTEDALPAVQPVN
Mflv_1183|M.gilvum_PYR-GCK          -----MDAKTSSDAPVTELSESESWDLLGSVSLGRLVTTVNGWTEIFPVN
MAB_1041|M.abscessus_ATCC_1997      --------MTPDSQPVTLLEKYESWTLLSSAKLGRLVVVIDGKPEIFPIN
Mvan_0633|M.vanbaalenii_PYR-1       --------MSQEAQPISILSASECWDLLAGAPLGRLVTSTEGEPHIFPVN
MAV_4110|M.avium_104                --------MPVTDDGVEILPVHECWDLLRGLTLGRLVTHADGQPDIFPVN
TH_3638|M.thermoresistible__bu      --------MTCED--VTLLSETECWELLAGRAVGRLVTCVDDEPHIFPVN
MMAR_1549|M.marinum_M               ----------MAQRELEELSDAECFELLATGRVGRLVYQDDLGPLAVPVN
MUL_3483|M.ulcerans_Agy99           --MRADENRVMAQRELEELSDAECFELLATGRVGRLVYQDDLGPVAVPVN
                                                   :  *   :.  **     **:*      .   *:*

Mb0083|M.bovis_AF2122/97            HLVVDGRVIVRTRLTAKVSVAVRSSADAGVVVAYEADDLD---PRRRTGW
Rv0080|M.tuberculosis_H37Rv         HLVVDGRVIGRTRLTAKVSVAVRSSADAGVVVAYEADDLD---PRRRTGW
MSMEG_5136|M.smegmatis_MC2_155      FRLSHDDVIIRVAGGGKLSAAAKN-----QVVAFEADELD---PDLRTGW
Mflv_1183|M.gilvum_PYR-GCK          FVVQKNTLLFRTAEGTKLLTAALN-----EYVVFEADDH-----NVAEGW
MAB_1041|M.abscessus_ATCC_1997      FVTQRGTVLFRTAEGTKLFGAVVS-----DQVLFEADDY-----NDIGGW
Mvan_0633|M.vanbaalenii_PYR-1       FAVQNRTVLFRTAEGTKLVASAIS-----KEVLFEADGY-----EDTQGW
MAV_4110|M.avium_104                YVVQRRTVLFRTAEGTKLISAAIN-----NRVLFEVDDH-----NVAGAW
TH_3638|M.thermoresistible__bu      YAVQRRTILFRTGEGAKLISVGIN-----KQVAFEADDYGFDECGHGAAW
MMAR_1549|M.marinum_M               YAMAGHDIVLRVEGGAKQAAMAQP------MLAFEVDHVD---EGQQSAW
MUL_3483|M.ulcerans_Agy99           YAMAGHDIVVRVEGGAKQAAMAQP------MLAFEVDHVD---EGQQSAW
                                    .      :: *.    *              : :*.*           .*

Mb0083|M.bovis_AF2122/97            SVVVTGLATEVSDP---EQVARYQ-RLLHPWVNMAMDTVVAIEPEIVTG-
Rv0080|M.tuberculosis_H37Rv         SVVVTGLATEVSDP---EQVARYQ-RLLHPWVNMAMDTVVAIEPEIVTG-
MSMEG_5136|M.smegmatis_MC2_155      SVTVVGHAEPITDI---DQLVEVAGTFVQPWVDGKRDHFVRIRTERITGR
Mflv_1183|M.gilvum_PYR-GCK          SVVVRGKARLLATS---NEIAEARRGGLYPWIATQKERFVRITPQTLTGR
MAB_1041|M.abscessus_ATCC_1997      SVVVRGAAQVLSTS---VEIDEADGAGLYPWIPTLKLHYVRIIPAQITGR
Mvan_0633|M.vanbaalenii_PYR-1       SVIVKGTARSLHTE---EEIAEAETANLVPWTATVKNHFVRIRPLNITGR
MAV_4110|M.avium_104                TVIIRGIARSLRTT---EEIEEAERAQVLPWTRSEKTHYVRIVPESVTGR
TH_3638|M.thermoresistible__bu      SVVVEGVARTLHTP---DQIALAEQAQVLPWTAGRKDHYVRIFPTRVTGR
MMAR_1549|M.marinum_M               SVLVRGPGAEVDMERIPALLREMDGHFPKPWALGIHNVWLRIVPTTITGR
MUL_3483|M.ulcerans_Agy99           SVLVRGPGAEVDMERIPALLREMDGHFPKPWALGIHNVWLRIVPTTITER
                                    :* : * .  :        :         **        : * .  :*  

Mb0083|M.bovis_AF2122/97            -IR---------IVADSRTP-
Rv0080|M.tuberculosis_H37Rv         -IR---------IVADSRTP-
MSMEG_5136|M.smegmatis_MC2_155      QIRERGVPHYQGAEAQTSTP-
Mflv_1183|M.gilvum_PYR-GCK          RFVFGP------EPEVTGLSS
MAB_1041|M.abscessus_ATCC_1997      RFVFGR------EPDGGHVPG
Mvan_0633|M.vanbaalenii_PYR-1       RFVFGA------RPAGS----
MAV_4110|M.avium_104                RFRFG-------SPAG-----
TH_3638|M.thermoresistible__bu      RFTLN-------RPEGA----
MMAR_1549|M.marinum_M               RLG---------GQRRSW---
MUL_3483|M.ulcerans_Agy99           RLG---------GQRRSW---
                                     :