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TDGRVRCGWATPGSDGSTLYLDYHDTEWGRPLRDGDALFERVSLEAFQSGLSWLTILRKRENFRRAFHGF DPERVARYTDKDIERLMGDAGIVRNRAKIEATIANARAVEELDVDFGELLWSFAPPARPRPADMSQVPAV TPESTAMAKELKRRGFRFVGPTTAYALMQATGMVDDHVATCWVPPLRHGQDLRHAQAKAGSSHTLRPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5082 | tag | - | 100% (209) | DNA-3-methyladenine glycosylase I |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1242 | tagA | 1e-74 | 72.11% (190) | DNA-3-methyladenine glycosylase I |
| M. gilvum PYR-GCK | Mflv_2189 | - | 5e-72 | 70.26% (195) | DNA-3-methyladenine glycosylase I |
| M. tuberculosis H37Rv | Rv1210 | tagA | 1e-74 | 72.11% (190) | DNA-3-methyladenine glycosylase I |
| M. leprae Br4923 | MLBr_01066 | tagA | 1e-73 | 71.96% (189) | DNA-3-methyladenine glycosidase I |
| M. abscessus ATCC 19977 | MAB_1349 | - | 1e-76 | 77.09% (179) | DNA-3-methyladenine glycosylase I TagA |
| M. marinum M | MMAR_4228 | tagA | 7e-75 | 72.77% (191) | DNA-3-methyladenine glycosylase I TagA |
| M. avium 104 | MAV_1355 | - | 5e-74 | 73.66% (186) | DNA-3-methyladenine glycosylase I |
| M. thermoresistible (build 8) | TH_0552 | tagA | 8e-80 | 74.60% (189) | PROBABLE DNA-3-METHYLADENINE GLYCOSYLASE I TAGA (TAG I) |
| M. ulcerans Agy99 | MUL_0961 | tagA | 5e-75 | 72.77% (191) | DNA-3-methyladenine glycosylase I TagA |
| M. vanbaalenii PYR-1 | Mvan_4506 | - | 1e-75 | 72.92% (192) | DNA-3-methyladenine glycosylase I |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5082|M.smegmatis_MC2_155 MTDGR---------VRCGWATPG---SDGSTLYLDYHDTEWGRPLRDGDA
MAB_1349|M.abscessus_ATCC_1997 MPSKEP--------TRCAWAVD----SAGSTLYTEYHDTEWGRPLYGRDA
Mb1242|M.bovis_AF2122/97 MSGDGL--------VRCPWAEVR--PGPDAQLYRDYHDNEWGRPLYGRVA
Rv1210|M.tuberculosis_H37Rv MSGDGL--------VRCPWAEVR--PGPDAQLYRDYHDNEWGRPLYGRVA
MMAR_4228|M.marinum_M MN-DGL--------RRCDWAEIR--PGPDAQTYRDYHDQEWGRPLYGQVA
MUL_0961|M.ulcerans_Agy99 MN-DGL--------RRCDWAEIR--PGPDAQTYRDYHDQEWGRPLYGQVA
MLBr_01066|M.leprae_Br4923 MSDDGL--------VRCGWADVR--SGLHWQLYRNYHDQEWGSPVRCGVA
MAV_1355|M.avium_104 MSDDEP--------IRCGWATAR--SGPDFELYRDYHDREWGQTVRDGVA
Mflv_2189|M.gilvum_PYR-GCK MSDVEP-----DARTRCGWIDESRLSPEDFTLYRDYHDDEWGRPLYGSAA
Mvan_4506|M.vanbaalenii_PYR-1 MTAAPA-----DPRVRCGWIDQSRLSAADFELYREYHDTEWGRPLRDSAA
TH_0552|M.thermoresistible__bu VTGPADGSSFDDGRTRCGWIDPARLSPADFLLYRDYHDTEWGQPVRDSAA
: ** * * :*** *** .: *
MSMEG_5082|M.smegmatis_MC2_155 LFERVSLEAFQSGLSWLTILRKRENFRRAFHGFDPERVARYTDKDIERLM
MAB_1349|M.abscessus_ATCC_1997 LFERLCLEAFQSGLAWITILRKREGFRRAFDGFRPEKVARYTDQDIARLM
Mb1242|M.bovis_AF2122/97 LFERMSLEAFQSGLSWLIILRKRENFRRAFSGFDIDKIARYTDTDVRRLL
Rv1210|M.tuberculosis_H37Rv LFERMSLEAFQSGLSWLIILRKRENFRRAFSGFDIDKIARYTDTDVRRLL
MMAR_4228|M.marinum_M LFERMSLEAFQSGLSWLIILRKRENFRRAFCGFDIEKVAGYTDADVQRLL
MUL_0961|M.ulcerans_Agy99 LFERMSLEAFQSGLSWLIILRKRENFRRAFCGFDIEKVAGYTDADVQRLL
MLBr_01066|M.leprae_Br4923 LFERMSLEAFQSGLSWLLILRKRENFRRAFSGFDIEEVARYTHADVQRLL
MAV_1355|M.avium_104 LFERMSLEAFQSGLSWLTILRKRENFRRAFSGFDIDAVAGYTDADVQRLM
Mflv_2189|M.gilvum_PYR-GCK LFERVSLEAFQSGLSWLIILRKRDNFRAAFDGFDVERIASYGDGEVARLM
Mvan_4506|M.vanbaalenii_PYR-1 LFERVSLEAFQSGLSWLIILRKRDNFRAAFDGFEVERIARYTDRDVERLM
TH_0552|M.thermoresistible__bu LFERISLEAFQSGLSWLVILRKRDNFRRAFDGFDIERVAGYTDRDVERLL
****:.********:*: *****:.** ** ** : :* * . :: **:
MSMEG_5082|M.smegmatis_MC2_155 GDAGIVRNRAKIEATIANARAVEELD---VDFGELLWSFAPP---ARPRP
MAB_1349|M.abscessus_ATCC_1997 ADAEIVRNRAKIESAISNARAVLDLD---TDLSDLLWSFAPK---RRARP
Mb1242|M.bovis_AF2122/97 ADDGIVRNRAKIEATIANARAAADLGSS-EDLSELLWSFAPP---PRPRP
Rv1210|M.tuberculosis_H37Rv ADDGIVRNRAKIEATIANARAAADLGSS-EDLSELLWSFAPP---PRPRP
MMAR_4228|M.marinum_M ADEGIVRNRAKIEATISNARAVIGLGSE-QDLSELLWSFAPP---ARPRP
MUL_0961|M.ulcerans_Agy99 ADEGIVRNRAKIEATISNARAVIGLGSE-QDLSELLWSFAPP---ARPRP
MLBr_01066|M.leprae_Br4923 FDDGIVRNRVKIEATIANARAAAELGSA-ADLSELLWSFAPQ---PRSRP
MAV_1355|M.avium_104 ADPGIVRNRAKIEATIANARAAAELGGA-TQLAELLWSFAPA---PRSRP
Mflv_2189|M.gilvum_PYR-GCK SDAGIVRNRAKIDATISNARAVIEMAEAGDDLGELLWSFAPSDRMTRPRP
Mvan_4506|M.vanbaalenii_PYR-1 ADPGIVRNRAKIDATIANARVAADMADAGDDLGELLWSFAPPDRVTRVRP
TH_0552|M.thermoresistible__bu ADAGIVRNRAKIEATIANARVAADLD---VELSDLLWSFAPADAARRPRP
* *****.**:::*:***.. : ::.:******* * **
MSMEG_5082|M.smegmatis_MC2_155 ADMSQVPAVTPESTAMAKELKRRGFRFVGPTTAYALMQATGMVDDHVATC
MAB_1349|M.abscessus_ATCC_1997 QLLSEVPAVTEESTAMAKELKRRGFRFVGPTTAYALMQATGMVDDHVRSC
Mb1242|M.bovis_AF2122/97 VDGSEIPSVSTESKAMSRELKRRGFRFVGPTTAYALMQATGMVDDHIQAC
Rv1210|M.tuberculosis_H37Rv VDGSEIPSVSTESKAMSRELKRRGFRFVGPTTAYALMQATGMVDDHIQAC
MMAR_4228|M.marinum_M ATLAEIPSATAESKAMARELKRRGFRFVGPTTAYALMQATGMVDDHLRGC
MUL_0961|M.ulcerans_Agy99 ATLAEIPSATAESKAMARELKRRGFRFVGPTTAYALMQATGMVDDHLRGC
MLBr_01066|M.leprae_Br4923 ADGSEIPSTSAEAKAMARELKRRGFRFVGPTTAYALMQATGMVDDHICTC
MAV_1355|M.avium_104 ADASEIPSATAESTAMAGELKRRGFRFVGPTTAYALMQATGMVDDHIRGC
Mflv_2189|M.gilvum_PYR-GCK ASLSDVVAVSPESTAMAKELKKRGFRFVGPTTAYALMQATGMVDDHTADC
Mvan_4506|M.vanbaalenii_PYR-1 ASMSEIAAVTPESKAMAKELKKRGFRFVGPTTAYALMQATGMVDDHVANC
TH_0552|M.thermoresistible__bu ADMSQIPATSPESVAMARELKRRGFRFIGPTTAYALMQATGMVDDHTAGC
::: :.: *: **: ***:*****:****************** *
MSMEG_5082|M.smegmatis_MC2_155 WVPPLRHGQDLRHAQAKAGSSHTLRPG
MAB_1349|M.abscessus_ATCC_1997 WVP--------RAETAPI---------
Mb1242|M.bovis_AF2122/97 WVPTERPFDQPGCPMAAR---------
Rv1210|M.tuberculosis_H37Rv WVPTERPFDQPGCPMAAR---------
MMAR_4228|M.marinum_M WVP----------PIVR----------
MUL_0961|M.ulcerans_Agy99 WVP----------PIVR----------
MLBr_01066|M.leprae_Br4923 WVP----------PTR-----------
MAV_1355|M.avium_104 WVP----------AAVR----------
Mflv_2189|M.gilvum_PYR-GCK WAP----------RLQG----------
Mvan_4506|M.vanbaalenii_PYR-1 WVP----------RADGG---------
TH_0552|M.thermoresistible__bu WVP----------RASRVTS-------
*.*