For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_4521 (-)

annotation: Tat (twin-arginine translocation) pathway signal sequence
coordinates: 4608450 - 4609616
length: 388

VTALTRRALLAGAGGLTAAGGLFGLGGLAHSALFSAPDAGGALRVGYLPITDAAPLLIAHSAGLYPAWAV
STSRPVLFRSWAALAEAFISRQIDVAHLLMPMAVQLRYTLGAGVRVLGWNHTNGSALTVAPRVQELGDLA
GSQVAIPFWWSIHNVVLQQLLRAHGLRPVVRRSASRSERTVELVVMSPSDMVPALANGTLGGYVVADPFN
AAAQIKKIGRIHTFLGDVWRDHACCALVTRDDVIAGRPQAVQAVADAVVGAQLRIDADRAAAAAALTEGR
YLPQPTPAVTLALTYPNPPYPLAHPDWLPQRLGFRPFPYPSFTRRLVEAMCDTVVDGDRKFLDRLDPAAV
HDDLVEDRFVRRSMSAHGGPDAFGPTADLTRTEQVQFS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4521--100% (388)Tat (twin-arginine translocation) pathway signal sequence

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCK-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2462-1e-16875.07% (381) putative sulfonate ABC transporter, periplasmic protein
M. marinum M-----
M. avium 104-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_4521|M.smegmatis_MC2_155      MTALT-RRALLAGAGGLTAAGGLFGLGGLAHSALFSAPDAGGALRVGYLP
MAB_2462|M.abscessus_ATCC_1997      MNGRAPRRAVLTGAAGIAATAGLFGATGLVRAAMFDGTNSTGQLRIGYLP
                                    *.. : ***:*:**.*::*:.****  **.::*:*...:: * **:****

MSMEG_4521|M.smegmatis_MC2_155      ITDAAPLLIAHSAGLYPAWAVSTSRPVLFRSWAALAEAFISRQIDVAHLL
MAB_2462|M.abscessus_ATCC_1997      ITDAAPLLYAHSAGLYPAGAVSAAKPVLFRSWAALAEAFMARQIDVVHLL
                                    ******** ********* ***:::**************::*****.***

MSMEG_4521|M.smegmatis_MC2_155      MPMAVQLRYTLGAGVRVLGWNHTNGSALTVAPRVQELGDLAGSQVAIPFW
MAB_2462|M.abscessus_ATCC_1997      MPMAIQLRQVLGHGVRVLGWNHTNGSALTVAPDIEHLEDLAGTAVAIPFW
                                    ****:*** .** ******************* ::.* ****: ******

MSMEG_4521|M.smegmatis_MC2_155      WSIHNVVLQQLLRAHGLRPVVRRSASRSERTVELVVMSPSDMVPALANGT
MAB_2462|M.abscessus_ATCC_1997      WSIHNIVLQELLRAHGLRPVIRGTASRVRRTVELVVMSPSDMVPALANRS
                                    *****:***:**********:* :*** .******************* :

MSMEG_4521|M.smegmatis_MC2_155      LGGYVVADPFNAAAQIKKIGRIHTFLGDVWRDHACCALVTRDDVIAGRPQ
MAB_2462|M.abscessus_ATCC_1997      IGGYVVADPFNAIAQIKKIGRIHTFLGDVWRDHACCALVTREDVIERRAD
                                    :*********** ****************************:***  *.:

MSMEG_4521|M.smegmatis_MC2_155      AVQAVADAVVGAQLRIDADRAAAAAALTEGRYLPQPTPAVTLALTYPNPP
MAB_2462|M.abscessus_ATCC_1997      AVQGVTDAVVAAQLRVDTDRKSAATTLGGGKYLPQSVLAVQTALTYPNPP
                                    ***.*:****.****:*:** :**::*  *:****.. **  ********

MSMEG_4521|M.smegmatis_MC2_155      YPLAHPDWLPQRLGFRPFPYPSFTRRLVEAMCDTVVDGDRKFLDRLDPAA
MAB_2462|M.abscessus_ATCC_1997      YPLKHPDWYPQRLGYQPFPYRSFTQRLVESMHDTVVDGDRAFLDRLDPAR
                                    *** **** *****::**** ***:****:* ******** ******** 

MSMEG_4521|M.smegmatis_MC2_155      VHDDLVEDRFVRRSMSAHGGPDAFGPTADLTRTEQVQFS
MAB_2462|M.abscessus_ATCC_1997      VHDDLVDDTFVRRAIAAHGGPEAFGITPQFARIEQVQVL
                                    ******:* ****:::*****:*** *.:::* ****.