For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TLPLLNGKAADITGPGRTDRFGVTCTDLGASVLAPDGKLVSVFGDTFSGHRVGQGDWRSPVVLIGTGDAD HEIVYERAGGPDPGYARQLWHYIHDDAASGWRRGGISTVIPSDLLRVGDSLYLHAIVNRGFGNVIWTEIW RSDDCGVSWDHLGERAKFPAGWHGGHAQCWSWDHDPDDGWVYVAATGFQRKQGIILMRVRPAHIGDRTCY VSWGYTGRRWEWGERATPITPAEERWGELSFRRLGPGRWILGGFFASRYALGYRVVDSPVANMHTTQVQT PVLGCAWHDEHHEGSRVAQLYGGYVLPGSRLDRTGGIGLVVSQWHTDSGWPYRAMQFKARLKDTATAPPS VL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4352 | - | - | 100% (353) | putative secreted protein |
| M. smegmatis MC2 155 | MSMEG_6255 | - | 7e-26 | 29.73% (333) | hypothetical protein MSMEG_6255 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3734c | - | 5e-22 | 28.19% (337) | hypothetical protein Mb3734c |
| M. gilvum PYR-GCK | Mflv_1306 | - | 7e-22 | 29.04% (365) | hypothetical protein Mflv_1306 |
| M. tuberculosis H37Rv | Rv3707c | - | 6e-22 | 28.19% (337) | hypothetical protein Rv3707c |
| M. leprae Br4923 | MLBr_02321 | - | 1e-21 | 27.46% (335) | hypothetical protein MLBr_02321 |
| M. abscessus ATCC 19977 | MAB_0346 | - | 2e-25 | 29.74% (343) | hypothetical protein MAB_0346 |
| M. marinum M | MMAR_5220 | - | 4e-20 | 27.60% (337) | hypothetical protein MMAR_5220 |
| M. avium 104 | MAV_0331 | - | 2e-25 | 30.23% (354) | hypothetical protein MAV_0331 |
| M. thermoresistible (build 8) | TH_0769 | - | 4e-22 | 35.03% (197) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4295 | - | 7e-20 | 27.30% (337) | hypothetical protein MUL_4295 |
| M. vanbaalenii PYR-1 | Mvan_5502 | - | 8e-25 | 30.22% (364) | hypothetical protein Mvan_5502 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5220|M.marinum_M --------------------------------------------------
MUL_4295|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02321|M.leprae_Br4923 --------------------------------------------------
Mb3734c|M.bovis_AF2122/97 --------------------------------------------------
Rv3707c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1306|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5502|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0769|M.thermoresistible__bu --------------------------------------------------
MAB_0346|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0331|M.avium_104 MQLTNLSEAELIASAGGDPWAINQSLQAGSPFQISQLAQAFHTAGRCTAE
MSMEG_4352|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_5220|M.marinum_M --------------------------------------------------
MUL_4295|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02321|M.leprae_Br4923 --------------------------------------------------
Mb3734c|M.bovis_AF2122/97 --------------------------------------------------
Rv3707c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1306|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5502|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0769|M.thermoresistible__bu --------------------------------------------------
MAB_0346|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0331|M.avium_104 ADHAFEDARKRFDAAWNHQNGDHPINDSDEVQRVTKSLGAQSLQLPKIGA
MSMEG_4352|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_5220|M.marinum_M --------------------------------------------------
MUL_4295|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02321|M.leprae_Br4923 --------------------------------------------------
Mb3734c|M.bovis_AF2122/97 --------------------------------------------------
Rv3707c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1306|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5502|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0769|M.thermoresistible__bu --------------------------------------------------
MAB_0346|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_0331|M.avium_104 DLEGIAASLAEAQKAGAQEIAELERELRGLDNITGAINHDLTLDLSASER
MSMEG_4352|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_5220|M.marinum_M ------------------MSPALVARCSLLVVLVIVASQCVWTAH--ADP
MUL_4295|M.ulcerans_Agy99 ------------------MSSALVVRCSLLVVLVIVASQCFWIAH--ADP
MLBr_02321|M.leprae_Br4923 --------------------------------------------------
Mb3734c|M.bovis_AF2122/97 --------------------------------------------------
Rv3707c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1306|M.gilvum_PYR-GCK ------------------------MRRNRIPAGLLAAFLCWNAIS--APV
Mvan_5502|M.vanbaalenii_PYR-1 -----------------------------MPG-------AANATP--APE
TH_0769|M.thermoresistible__bu --------------------------------------------------
MAB_0346|M.abscessus_ATCC_1997 ---------------MAPGGAGRETRVRLVAVLVTAATLVVAELLGDASA
MAV_0331|M.avium_104 SELESLKKAVHADAVDDVRDALKQMNSIRNGYSETLRKSMDSLHTEGYDP
MSMEG_4352|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_5220|M.marinum_M PAPGPVPILPPLAPGQVLRMGPTAGTGTPTGDYGIGATDLCEFVEFP---
MUL_4295|M.ulcerans_Agy99 PAPGPAPILPPLAPGQVLRMGPTAGTGTPTGDYGIGATDLCEFVEFP---
MLBr_02321|M.leprae_Br4923 ------------MPGQVLRIGPMAGTGTRTGDYGIGATDLCEFIEFP---
Mb3734c|M.bovis_AF2122/97 ----------------MLRIGPTAGTGTPTGDYGIGATDLCEFVEFP---
Rv3707c|M.tuberculosis_H37Rv ----------------MLRIGPTAGTGTPTGDYGIGATDLCEFVEFP---
Mflv_1306|M.gilvum_PYR-GCK VAHATPVGVQPLMPGQVLRLGVAAGTGTATADYGIGATDLCEFMEFP---
Mvan_5502|M.vanbaalenii_PYR-1 LP--------PLLPGQVLRLGPAAGTGTPTADYGIGATDLCEFMEFP---
TH_0769|M.thermoresistible__bu --------------------------------------------------
MAB_0346|M.abscessus_ATCC_1997 SADPLRPVSPPLDPGEVVRIGPVAGTGTATAEYNLGATDLCEFMVFT---
MAV_0331|M.avium_104 PTTVDTWMESPLKPGEVRDLGPVAGTGGVPGIPGIGAADLGEVVEIPGQP
MSMEG_4352|M.smegmatis_MC2_155 -------MTLPLLNGKAADITGPG----RTDRFGVTCTDLGASVLAPD--
MMAR_5220|M.marinum_M TELLQVCGDSFAGQGVGFGGWYSPIALRVDTASVDDP----AGVRYTGVT
MUL_4295|M.ulcerans_Agy99 TELLQVCGDSFAGQGVGFGGWYSPIALRVDTASVDDP----AGVRYTGVT
MLBr_02321|M.leprae_Br4923 AELLQICGDSFAGQGVGFGGWYSPVALHVDTASVDDP----TGVRYIGVT
Mb3734c|M.bovis_AF2122/97 SQLLQVCGDSFAGQGVGFGGWYAPVALHVDTESIDDP----AGVRYTGVT
Rv3707c|M.tuberculosis_H37Rv SQLLQVCGDSFAGQGVGFGGWYAPVALHVDTESIDDP----AGVRYTGVT
Mflv_1306|M.gilvum_PYR-GCK SGTLQVCGDSFAGQAVGFGGWYSPIALHVVGDTLEDP----GGVRYNGVT
Mvan_5502|M.vanbaalenii_PYR-1 SGILQVCGDSFAGQGVGFGGWFSPIALHVVGESLDDP----AGVRYDGVT
TH_0769|M.thermoresistible__bu -------------------------------------------VRYDGVT
MAB_0346|M.abscessus_ATCC_1997 GGMLQVCGDSFAGQGVGYGGWHSPVALRVDTESVPDA----TGVRHSGVL
MAV_0331|M.avium_104 GKYLAIFGDSFSGNKMGEGEHYRSVAVPVTFDAEGHPH---FGAPLTGPE
MSMEG_4352|M.smegmatis_MC2_155 GKLVSVFGDTFSGHRVGQGDWRSPVVLIGTGDADHEIVYERAGGPDPGYA
*
MMAR_5220|M.marinum_M GIGSPLLADPTPAG------NSQLPAGVVQINRHNYLMVTTTKD-LEPQS
MUL_4295|M.ulcerans_Agy99 GIGSPLLADPTPAG------NSQLPAGVVQINRHNYLMVTTTKD-LEPQS
MLBr_02321|M.leprae_Br4923 GVDKPLLADPAPPG------DSQLPAGVVQINRHNYLMVTTTKN-LEPQD
Mb3734c|M.bovis_AF2122/97 GVGTPLLADPTPPG------DSQLPAGVVQINRRNYLMVTTTKD-LQPQN
Rv3707c|M.tuberculosis_H37Rv GVGTPLLADPTPPG------DSQLPAGVVQINRRNYLMVTTTKD-LQPQN
Mflv_1306|M.gilvum_PYR-GCK GVDTPLLAEPTLPG------ESQLPAGIIEINRENWMLVTTTRD-LVPQR
Mvan_5502|M.vanbaalenii_PYR-1 GVDTPLLADPAPAG------ASQLPAGVIEINRENWMMVTTTKD-LRPQT
TH_0769|M.thermoresistible__bu GVHTPLLADPTPPG------GSQLPAGVVQINRENYLLVTTVRD-LVPQH
MAB_0346|M.abscessus_ATCC_1997 GTDRPLLADAAPPG------FSQLPSGVIDINGTNWLLVAVTKN-LVPQS
MAV_0331|M.avium_104 GSGHELFPIPSDAKG----VTDTLPSGTITLGDKTYMMVTGTKDDLKPVA
MSMEG_4352|M.smegmatis_MC2_155 RQLWHYIHDDAASGWRRGGISTVIPSDLLRVGDSLYLHAIVNRG-FGNVI
: : . :*:. : :. :: . :. :
MMAR_5220|M.marinum_M SRLVLAVPERA-GWQTIAGTQRAARYQDGSQTQISGYYDPIPTPDSPGGW
MUL_4295|M.ulcerans_Agy99 SRLVLAVPERA-GWQTIAGTQRAARYQDGSQTQIRGYYDPIPTPDSPGGW
MLBr_02321|M.leprae_Br4923 SRLVTAEPARV-GWQTVPGSRRAATSQDSRQTQISGYYDPIPTPDSSSGW
Mb3734c|M.bovis_AF2122/97 SRLVRAEAARG-GWQTVSGSRRNAAYQDGRQTQISGYYDPVPTPDSPTGW
Rv3707c|M.tuberculosis_H37Rv SRLVRAEAARG-GWQTVSGSRRNAAYQDGRQTQISGYYDPVPTPDSPTGW
Mflv_1306|M.gilvum_PYR-GCK SRLVKAEAGQG-NWQTVPGSEREAGFAGGRQTQISGYYDPIPTADSGRGW
Mvan_5502|M.vanbaalenii_PYR-1 SRLVKAVAGQG-NWETIVGSERDAGYAGGRQSQISGYYDPIPTAESPRGW
TH_0769|M.thermoresistible__bu SRLVKAEAGRG-GWQTVPGSQRDFDHLDGRQSQLSGYYDPIPTAESETGW
MAB_0346|M.abscessus_ATCC_1997 TRLVKPDPFRA-GWATVPGSVRPGDYEGGRQTQISGYYDPLWTQDSPKGW
MAV_0331|M.avium_104 SWLVEVNGDPGKGWTMVPGSFRGAG---DAPTQVSGYKG-------SDGK
MSMEG_4352|M.smegmatis_MC2_155 WTEIWRSDDCGVSWDHLGERAKFPAGWHGGHAQCWSWDH-----DPDDGW
: .* : : . :* .: *
MMAR_5220|M.marinum_M VYIVADNFTRRDPVLLYRATPQTFIDRSKWQGWAGGP--GGGWNKP---P
MUL_4295|M.ulcerans_Agy99 VYIVADNFTRRDPVLLYRATPQTFIDRSKWQGWAGGP--GGGWNKP---P
MLBr_02321|M.leprae_Br4923 VYIVANSFTRRDSVQLFRVTPQTFTDRSRWQGWAAGP--DGGWNKP---P
Mb3734c|M.bovis_AF2122/97 VYIVADSFTRGEPAVLYRATPESFTDRSRWQGWAGGP--DGGWNKP---P
Rv3707c|M.tuberculosis_H37Rv VYIVADSFTRGEPAVLYRATPESFTDRSRWQGWAGGP--DGGWNKP---P
Mflv_1306|M.gilvum_PYR-GCK VYIVANNFDRSSPAVLYRATPQTFTDRSSWQGWTGA-----GWGGD---P
Mvan_5502|M.vanbaalenii_PYR-1 VYIVANNFDRSGPAVLYRATPASFTDRATWQGWTGV-----AWGGE---P
TH_0769|M.thermoresistible__bu VYIVTNNFDRSSPVLLFRVAPENFTDRSSWQGWSGLPGPDGGWGKP---P
MAB_0346|M.abscessus_ATCC_1997 VYIVSDGFDRSHPAVLYRAKPDTFTDRATWQGWGVDAQGKGAWGRP---P
MAV_0331|M.avium_104 VYIAADSFDRSRGITMYRADPANVFERDKWQPWTGKD-----WGNPRDQA
MSMEG_4352|M.smegmatis_MC2_155 VYVAATGFQRKQGIILMRVRPAHIGDRTCYVSWGYTG-RRWEWGER-ATP
**:.: .* * : *. * . :* : * *. .
MMAR_5220|M.marinum_M TPLWPDQVGEMSIRQID-GMTVLSYFN--ATTLNMEVRVAANPT-LLGDA
MUL_4295|M.ulcerans_Agy99 TPLWRDQVGEMSIRQID-GMTVLSSFN--ATTLNMEVRVAANPT-LLGNA
MLBr_02321|M.leprae_Br4923 TPLWPDKVGEMCIKQIG-GQAVLSYFN--ATTGNMEVRVAADPT-LLGTS
Mb3734c|M.bovis_AF2122/97 TPLWPDQLGEMSIRQID-GQTVLSYFN--ASTGNMEVRVAHHPT-SLGAA
Rv3707c|M.tuberculosis_H37Rv TPLWPDQLGEMSIRQID-GQTVLSYFN--ASTGNMEVRVAHHPT-SLGAA
Mflv_1306|M.gilvum_PYR-GCK APLWPDRVGEMSVRQID-GLTMLSYFN--ATTGNMEIRVASDPT-QLGTA
Mvan_5502|M.vanbaalenii_PYR-1 VPLWPDRVGEMSVRQID-GQTVLSYFN--ATTGNMEIRVAADPT-QLGTA
TH_0769|M.thermoresistible__bu TPLWPDRVGEMSVRQID-GKTVLSYFN--ATTGNMEIRVAAEPT-ALGTA
MAB_0346|M.abscessus_ATCC_1997 TPLWGDHLGEMSMKLVD-GQAVLSYFN--QTTGNVEVRVADSPT-RLGAV
MAV_0331|M.avium_104 VQVTNDRYGELSFREIG-GRPVLSGFNVDAHKGSVEVRVGTSPTDMFGAD
MSMEG_4352|M.smegmatis_MC2_155 ITPAEERWGELSFRRLGPGRWILGGFF--ASRYALGYRVVDSPVANMHTT
:: **:..: :. * :*. * : ** *. :
MMAR_5220|M.marinum_M PVTTVVQHDEWPEPAESLPPPFDNRLAQPYGGYISPGSTLDELR---IFV
MUL_4295|M.ulcerans_Agy99 PVTTVVQHDEWPEPAESLPPPFDNRLAQPYGGYISPGSTLDELR---IFV
MLBr_02321|M.leprae_Br4923 PVTTVVQHDEWPDPAESLPPPYDNRLAQPYGGYISPGSTLDELR---IFV
Mb3734c|M.bovis_AF2122/97 PVTTVVRHDEWPEPAESLPPPYDNRLAQPYGGYISPGSTIDELR---IFV
Rv3707c|M.tuberculosis_H37Rv PVTTVVRHDEWPEPAESLPPPYDNRLAQPYGGYISPGSTIDELR---IFV
Mflv_1306|M.gilvum_PYR-GCK PVTTVVVAAPWPDPVDVLPPPHDNRLAQPYGGYISPGSTPEAVR---VFV
Mvan_5502|M.vanbaalenii_PYR-1 PVTTVVVAAPWPDRVEDLPPPHDNRLAQPYGGYISPGSTPDAVR---VFV
TH_0769|M.thermoresistible__bu PVTTVVVASEWPDPAEHLPPPDDNRLAQPYGGYISPGSTLDEVR---VFI
MAB_0346|M.abscessus_ATCC_1997 PVTTVVNAGAWPAVADELPESWDNTLAQPYGGYIGPDSTLDRLS---IYV
MAV_0331|M.avium_104 VPTTLVVQNGDPGAPKFMP--------QPYGGYILPGSTLDDLK---LLG
MSMEG_4352|M.smegmatis_MC2_155 QVQTPVLGCAWHDEHHEGS-----RVAQLYGGYVLPGSRLDRTGGIGLVV
* * . . * ****: *.* : :
MMAR_5220|M.marinum_M SQWDTRARM-----SGPYRVIQFAVNPFKP--------------------
MUL_4295|M.ulcerans_Agy99 SQWDTRARM-----SGPYRVIQFAVNPFKP--------------------
MLBr_02321|M.leprae_Br4923 SQWDTRARV-----SELYRVIQFAVNPLKP--------------------
Mb3734c|M.bovis_AF2122/97 SQWDTRARQ-----NGPYRVIQFAVNPFKPWSDP----------------
Rv3707c|M.tuberculosis_H37Rv SQWDTRARQ-----NGPYRVIQFAVNPFKPWSDP----------------
Mflv_1306|M.gilvum_PYR-GCK SQWNTMARG-----GTPYRVIQYVVNPQKPW-------------------
Mvan_5502|M.vanbaalenii_PYR-1 SQWNTTPRG-----GSPYRVIQFAVNPIKPW-------------------
TH_0769|M.thermoresistible__bu SQWNTGPRG-----GSPYRVIQFAVNPYKPWDEPGHTSWESPFAGWRPPQ
MAB_0346|M.abscessus_ATCC_1997 SQWNTDSRD-----HAPYRVIEFAVNPLRAGVG-----------------
MAV_0331|M.avium_104 SQWNTAKDGNGVPIGTPYNTREFQLNPFH---------------------
MSMEG_4352|M.smegmatis_MC2_155 SQWHTDSGW-------PYRAMQFKARLKDTATAPPSVL------------
***.* *.. :: .
MMAR_5220|M.marinum_M -
MUL_4295|M.ulcerans_Agy99 -
MLBr_02321|M.leprae_Br4923 -
Mb3734c|M.bovis_AF2122/97 -
Rv3707c|M.tuberculosis_H37Rv -
Mflv_1306|M.gilvum_PYR-GCK -
Mvan_5502|M.vanbaalenii_PYR-1 -
TH_0769|M.thermoresistible__bu A
MAB_0346|M.abscessus_ATCC_1997 -
MAV_0331|M.avium_104 -
MSMEG_4352|M.smegmatis_MC2_155 -