For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_4273 (-)

annotation: integral membrane protein
coordinates: 4356838 - 4357524
length: 228

VKLLGRKNNDDDKNVASDAADSAVDEQNGPAAEDRPRTTPPKGRPTPKRSEAAKRRGPVAPAPLTAAEAR
ARRKEMRKTLTKEERKAEKITRRAEMAERRERMMAGEEAYLLPRDRGPVRRYVRDIVDSRRNILGLFMPA
ALAMIFFMLALPNVQAQQVLSYAMLALVAVMVLDGFYLGRKVNRMVDAKFPDNTEGGWKLGFYASSRASQ
LRRMRAPRPMVERGAKIA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4273--100% (228)integral membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2229-3e-7059.49% (237) transmembrane protein
M. gilvum PYR-GCKMflv_2943-2e-8670.48% (227) hypothetical protein Mflv_2943
M. tuberculosis H37RvRv2206-3e-7059.49% (237) transmembrane protein
M. leprae Br4923MLBr_00869-5e-4160.00% (125) hypothetical protein MLBr_00869
M. abscessus ATCC 19977MAB_1955c-2e-6757.33% (232) hypothetical protein MAB_1955c
M. marinum MMMAR_3250-3e-7662.55% (235) transmembrane protein
M. avium 104MAV_2285-4e-7462.34% (231) hypothetical protein MAV_2285
M. thermoresistible (build 8)TH_3608-5e-8665.16% (244) PUTATIVE conserved hypothetical protein
M. ulcerans Agy99MUL_3563-1e-7662.55% (235) transmembrane protein
M. vanbaalenii PYR-1Mvan_3570-2e-8872.05% (229) hypothetical protein Mvan_3570

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2943|M.gilvum_PYR-GCK          --------------------------MLGRRN-----------DDARDP-
Mvan_3570|M.vanbaalenii_PYR-1       MASTEVSQAAADWVARRPRSNLAGVKLLGRKN-----------DDAGEPE
MSMEG_4273|M.smegmatis_MC2_155      ------------------------MKLLGRKNN---------DDDKNVAS
TH_3608|M.thermoresistible__bu      ------------------------VNLLGRKKDNAQTTAGSTGADTAATT
MMAR_3250|M.marinum_M               ------------------------MKLLGRKKDH-----DEG-ADISAAS
MUL_3563|M.ulcerans_Agy99           ------------------------MKLLGRKKDH-----DEG-ADISAAS
Mb2229|M.bovis_AF2122/97            ------------------------MKLLGHRKSH-----GHQRADASPDA
Rv2206|M.tuberculosis_H37Rv         ------------------------MKLLGHRKSH-----GHQRADASPDA
MLBr_00869|M.leprae_Br4923          --------------------------------------------------
MAV_2285|M.avium_104                ------------------------MKLLGRKKDQ-----DEDLDEQTAAS
MAB_1955c|M.abscessus_ATCC_199      ------------------------MNLLGRKK-------------SAPSD
                                                                                      

Mflv_2943|M.gilvum_PYR-GCK          DEPDSTDAGTEIAAPVER---------TATAPKGKPTPKRSEAAR--RRG
Mvan_3570|M.vanbaalenii_PYR-1       DSVPAADDSADAAAAGER---------TTTPPKGKPTPKRSEATR--RRG
MSMEG_4273|M.smegmatis_MC2_155      DAADSAVDEQNGPAAEDRP--------RTTPPKGRPTPKRSEAAK--RRG
TH_3608|M.thermoresistible__bu      DPVSSGDSSDTGSGKTTRSERRRRKESRTTPPKGRPTPKRSESAR--RRG
MMAR_3250|M.marinum_M               DHADESAANSGDTSSAATS-----RGPKTTGPKGRPTPKRNDATR-SKKG
MUL_3563|M.ulcerans_Agy99           DHADESAANSGDTSSSATS-----RGPKTTGPKGRPTPKRNDATR-SKKG
Mb2229|M.bovis_AF2122/97            GSKDGCRPDSGRTSGSDTS-----RGSQTTGPKGRPTPKRNQSRRHTKKG
Rv2206|M.tuberculosis_H37Rv         GSKDGCRPDSGRTSGSDTS-----RGSQTTGPKGRPTPKRNQSRRHTKKG
MLBr_00869|M.leprae_Br4923          --------------------------------------------------
MAV_2285|M.avium_104                GGSDVAG------AADAAS-----REPRRTGPKGRPTPKRSEARRNARKG
MAB_1955c|M.abscessus_ATCC_199      DAAATSALPSGETSVTDAS-------GPAQAGKGRPTPKRDAGKR---RG
                                                                                      

Mflv_2943|M.gilvum_PYR-GCK          PVAPAPMTSAEARKRRKELRGPKLSREERKAERAERRAEMGERRERMMAG
Mvan_3570|M.vanbaalenii_PYR-1       PVAPAPLTSAEARKRRKEMRGPKLSREERKAERMVRRAEMSERREKMMAG
MSMEG_4273|M.smegmatis_MC2_155      PVAPAPLTAAEARARRKEMR-KTLTKEERKAEKITRRAEMAERRERMMAG
TH_3608|M.thermoresistible__bu      PVAPAPMTAAEARRRRKELR-KSMSKEERKALRAERRAQLNERRERMMAG
MMAR_3250|M.marinum_M               PVVPAPMTSAEARARRKKLARPKLSREERKAEKAAGRARMAERRERMMAG
MUL_3563|M.ulcerans_Agy99           PVVPAPMTSAEARARRKKLARPKLSREERKAEKAAGRARMAERRERMMAG
Mb2229|M.bovis_AF2122/97            PVAPAPMTAAQARARRKSLAGPKLSREERRAEKAANRARMTERRERMMAG
Rv2206|M.tuberculosis_H37Rv         PVAPAPMTAAQARARRKSLAGPKLSREERRAEKAANRARMTERRERMMAG
MLBr_00869|M.leprae_Br4923          ----------------------------------------------MMAG
MAV_2285|M.avium_104                PVAPAPMTASEARARRKTLAGPKLSREERRADKAANRARMSERRERMMAG
MAB_1955c|M.abscessus_ATCC_199      PVAPAPLTSAEARQRRKALRGPKLSRAERKVENAERRARMADNREKMMAG
                                                                                  ****

Mflv_2943|M.gilvum_PYR-GCK          EDAYLLPRDRGPVRRYVRDIVDARRNLLGLFMPAALGMIFIMLAVPSVEV
Mvan_3570|M.vanbaalenii_PYR-1       EDAYLLPRDRGPVRRYVRDVVDSRRNLLGLFMPSALFLIFVMLAAPSVKV
MSMEG_4273|M.smegmatis_MC2_155      EEAYLLPRDRGPVRRYVRDIVDSRRNILGLFMPAALAMIFFMLALPNVQA
TH_3608|M.thermoresistible__bu      EEDFLLPRDKGPVRRYVRDIVDARRNVLGLFMPAALALIFVMLSVPSVEV
MMAR_3250|M.marinum_M               DEAYLLPRDQGPVRRYVRDVVDARRNLLGLFMPSALALLFAMFAVP--QL
MUL_3563|M.ulcerans_Agy99           DEAYLLPRDQGPVRRYVRDVVDARRNLLGLFMPSALALLFAMFAVP--QL
Mb2229|M.bovis_AF2122/97            EEAYLLPRDRGPVRRYVRDVVDSRRNLLGLFMPSALTLLFVMFAVP--QV
Rv2206|M.tuberculosis_H37Rv         EEAYLLPRDRGPVRRYVRDVVDSRRNLLGLFMPSALTLLFVMFAVP--QV
MLBr_00869|M.leprae_Br4923          EEAYLPPRDQGPVRRYIRDLVDARRNALGLFTPSALVLLFITFGVP--QL
MAV_2285|M.avium_104                EEGYLLPRDQGPVRRYVRDIVDSRRNLLGLFMPSTLFLMFIMFGVP--QL
MAB_1955c|M.abscessus_ATCC_199      DEAYLLPRDKGPVRAFARDIVDSRRNVLGLFMPLALFLIFTMFAVPSVQV
                                    :: :* ***:**** : **:**:*** **** * :* ::*  :. *  : 

Mflv_2943|M.gilvum_PYR-GCK          QALISPAMLVLVLIMVVDGFFLGRKVNRMADAKFPDNTETGWKLGFYAAS
Mvan_3570|M.vanbaalenii_PYR-1       QAFLSPAMLVLVLIMVVDGFFLGRKVNRMADQKFPGNTETGWKLGFYAAS
MSMEG_4273|M.smegmatis_MC2_155      QQVLSYAMLALVAVMVLDGFYLGRKVNRMVDAKFPDNTEGGWKLGFYASS
TH_3608|M.thermoresistible__bu      QAAMSPAMLGLMVIMLIDAFVLGRKVNRMVDAKFPDNTETGWRLGFYAAS
MMAR_3250|M.marinum_M               QLYMSPAMLVLMALMTIDGIILARKVSNLVDVKFPNNTEGRWKLGLYAAG
MUL_3563|M.ulcerans_Agy99           QLYMSPAMLVLMALMTIDGIILARKVSNLVDVKFPNNTEGRWKLGLYAAG
Mb2229|M.bovis_AF2122/97            QFYLSPAMLILLALMTIDAIILGRKVGRLVDTKFPSNTESRWRLGLYAAG
Rv2206|M.tuberculosis_H37Rv         QFYLSPAMLILLALMTIDAIILGRKVGRLVDTKFPSNTESRWRLGLYAAG
MLBr_00869|M.leprae_Br4923          QLYMSPAMLVLLSVMGIDGIILGRKISKLVDVKFPSNTESHWRLGLYAAG
MAV_2285|M.avium_104                QLYISPAMLVLMAVMSIDGLILGRKVSRMVDAKFPNNTESRWKLGLYAAG
MAB_1955c|M.abscessus_ATCC_199      QMWMTPAMLVLMIVMIVDGIFVGRLVNKRVYERFPTSDEGGFKLGWYAAS
                                    *  :: *** *: :* :*.: :.* :.. .  :** . *  ::** **:.

Mflv_2943|M.gilvum_PYR-GCK          RASQLRRMRAPRPQVERGTPVA
Mvan_3570|M.vanbaalenii_PYR-1       RASQLRRMRAPRPQVERGTPVA
MSMEG_4273|M.smegmatis_MC2_155      RASQLRRMRAPRPMVERGAKIA
TH_3608|M.thermoresistible__bu      RASQLRRMRAPRPQVERGAEIT
MMAR_3250|M.marinum_M               RASQMRRMRAPRPKVERGASLD
MUL_3563|M.ulcerans_Agy99           RASQMRRMRAPRPKVERGASVD
Mb2229|M.bovis_AF2122/97            RASQIRRLRAPRPQVERGGDVG
Rv2206|M.tuberculosis_H37Rv         RASQIRRLRAPRPQVERGGDVG
MLBr_00869|M.leprae_Br4923          RASQMRRLRVPRPQVEHGSSVG
MAV_2285|M.avium_104                RASQMRRLRAPRPQVKHGSSVD
MAB_1955c|M.abscessus_ATCC_199      RASQLRKMRAPRPRVNRGEPV-
                                    ****:*::*.*** *::*  :