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PPIPPPESPSVPARISLFVGKGGVGKSTLATATAVRDAQAGQRVLIVSTDQAHSTGDVLGIELAPTGERA PTRVLADMDAGSDTGGLLDALALDTLALLEARWVEVAETLSARFGESDLGSVAPEELSALPGIQEVLGLY EVGELAESGQWDHVVVDCASTADALRMLTLPETFGLYLERAWPRHRRLSGTVDAATATIVALMERIDAGL RRVGSLLTDGSRVSAHLVLTPERVVAAEAARTLGSLALMGVEVAELLVNQILVQDDSFEYHNLPAHPAFD WYTERISEQQAVLDELDATIGDVSLVLVPHLAGEPIGPKALAELLEAARRRDGAPPPGPLKPIVDRESGS GLEAVYRMRLELPQVDSAALTLGRVDDDLIIGVGAMRRRVRLASVLRRCIVVDASLRGSQLTVRFRPNPE VWPV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4250 | - | - | 100% (425) | putative membrane transport ATPase |
| M. smegmatis MC2 155 | MSMEG_6195 | - | 2e-12 | 29.65% (172) | ion-transporting ATPase |
| M. smegmatis MC2 155 | MSMEG_6193 | - | 3e-08 | 23.31% (266) | anion-transporting ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2206c | - | 1e-156 | 73.23% (381) | hypothetical protein Mb2206c |
| M. gilvum PYR-GCK | Mflv_2965 | - | 1e-175 | 78.68% (380) | anion-transporting ATPase |
| M. tuberculosis H37Rv | Rv2184c | - | 1e-156 | 73.23% (381) | hypothetical protein Rv2184c |
| M. leprae Br4923 | MLBr_00890 | - | 1e-167 | 72.46% (414) | putative membrane transport ATPase |
| M. abscessus ATCC 19977 | MAB_1982 | - | 1e-155 | 65.16% (419) | putative arsenite-transporting ATPase |
| M. marinum M | MMAR_3228 | - | 1e-162 | 73.12% (398) | hypothetical protein MMAR_3228 |
| M. avium 104 | MAV_2310 | - | 1e-158 | 72.19% (392) | anion-transporting ATPase superfamily protein |
| M. thermoresistible (build 8) | TH_1108 | - | 1e-171 | 76.98% (391) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3539 | - | 1e-154 | 72.25% (382) | hypothetical protein MUL_3539 |
| M. vanbaalenii PYR-1 | Mvan_3546 | - | 0.0 | 79.08% (411) | arsenite-transporting ATPase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2206c|M.bovis_AF2122/97 --------------------------------------------------
Rv2184c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3228|M.marinum_M ----------------------------------MAAATAVCDATAGQRV
MUL_3539|M.ulcerans_Agy99 --------------------------------------------------
MAV_2310|M.avium_104 ----------------------------------------MAAAGAGQRV
MLBr_00890|M.leprae_Br4923 --------------MPASAQISLFVGKGGVGKSTLAAATAVRDAGEGRRV
Mflv_2965|M.gilvum_PYR-GCK -------------------------------------------------M
Mvan_3546|M.vanbaalenii_PYR-1 MRLTEGRGATDAAWTPGAARIGLFVGKGGVGKSTLATATAVRAARAGMRV
MSMEG_4250|M.smegmatis_MC2_155 ---MPPIPPPESPSVP--ARISLFVGKGGVGKSTLATATAVRDAQAGQRV
TH_1108|M.thermoresistible__bu ----------------------------------------VREARAGQRV
MAB_1982|M.abscessus_ATCC_1997 --MSRPGDAAPEVHAPPAATIGLFVGKGGVGKSTLAGATAVRHARAGQRV
Mb2206c|M.bovis_AF2122/97 MVVSTDQAHSLGDVLGIAVPPTGQGDPVRVLAYDP----EAGGGFLDALA
Rv2184c|M.tuberculosis_H37Rv MVVSTDQAHSLGDVLGIAVPPTGQGDPVRVLAYDP----EAGGGFLDALA
MMAR_3228|M.marinum_M LVVSTDQAHSLGDVLGIAVAPTGSGEPVRVFADLETGQVDTGGGFLDALA
MUL_3539|M.ulcerans_Agy99 MVVSTDQAHSLGDVLGIAVTPPGSGEPVRVFADLETGQVDTGGGFLDALA
MAV_2310|M.avium_104 LVVSTDQAHSLGDVLGVPVPPS-QAELVRVLADLETGRAEAGGGFLDALA
MLBr_00890|M.leprae_Br4923 LVVSTDQAHSLGDVLGVVVAPTGHGNPVRVLGCDA----EAGGGFLDALA
Mflv_2965|M.gilvum_PYR-GCK LIVSTDQAHSTGDVLGVSLVPTGLRRPTRVLADLDA--AGSGGGSLDALA
Mvan_3546|M.vanbaalenii_PYR-1 LIVSTDQAHSTGDVLGVNLVPTGRRDPTRVLAELDT--AESGGGFLDALA
MSMEG_4250|M.smegmatis_MC2_155 LIVSTDQAHSTGDVLGIELAPTGERAPTRVLADMDA--GSDTGGLLDALA
TH_1108|M.thermoresistible__bu LVVSTDQAHSTGDVLGVPVTPTGRREPTRVLADLEAS-AAVGGGSLDALA
MAB_1982|M.abscessus_ATCC_1997 LAVSTDQAHSLGDVFGVRVDPSPGAHCVRVIEDPY-------GGELDVMA
: ******** ***:*: : *. .**: ** **.:*
Mb2206c|M.bovis_AF2122/97 LDTLALLEGRWLHVVETLDRRFPGSELSSIAPEELCALPGIQEVLGLHAV
Rv2184c|M.tuberculosis_H37Rv LDTLALLEGRWLHVVETLDRRFPGSELSSIAPEELCALPGIQEVLGLHAV
MMAR_3228|M.marinum_M LDTLALLEDRWRDVVDALNGRFPDSELGSIAPEELSALPGVQEVLGLHAV
MUL_3539|M.ulcerans_Agy99 LDTLALLEDRWRDVVDALNGRFPDSELGSIAPEELSALPGVQEVLGLHAV
MAV_2310|M.avium_104 LDTLALLEARWRDVVAALDRRFPDSELSTIAPEELSALPGVQEVLGLHAV
MLBr_00890|M.leprae_Br4923 LDTLALLEARWCDVVDALDRRFPESELGSIAPEELSALPGIQEMLGLYTV
Mflv_2965|M.gilvum_PYR-GCK LDTLALLAARWLEVARPLAERFPDSDIGDIAPEELSALPGVQEVLGLHEV
Mvan_3546|M.vanbaalenii_PYR-1 LDTLALLSERWRSIAGPLAARFPESDVGDIAPEELSALPGVQEVLGLHEV
MSMEG_4250|M.smegmatis_MC2_155 LDTLALLEARWVEVAETLSARFGESDLGSVAPEELSALPGIQEVLGLYEV
TH_1108|M.thermoresistible__bu LDTLELLAARWAEVAGPVAARFPDSDLDILAPEELSALPGVQEVLGLHEV
MAB_1982|M.abscessus_ATCC_1997 LDTLGLLERRWGDIADTIAAQYPESDIGSLAPEELSALPGVQEMLGLHEV
**** ** ** :. .: :: *::. :*****.****:**:***: *
Mb2206c|M.bovis_AF2122/97 GELAAARRWDRIVVDCASTADALRMLTLPATFGLYVERAWPRHRRLSIGA
Rv2184c|M.tuberculosis_H37Rv GELAAARRWDRIVVDCASTADALRMLTLPATFGLYVERAWPRHRRLSIGA
MMAR_3228|M.marinum_M GELAASGRWDRIVVDCASTADALRMLTLPATFSLYVERAWPRHRRLSLAI
MUL_3539|M.ulcerans_Agy99 GELAASGRWDRIVVDCASTADALRMLTLPATFSLYVERAWPRHRRLSLAI
MAV_2310|M.avium_104 GELARSGRWDRVVVDCASTADALRMLTLPATFGLYVERAWPRHRRLSLTA
MLBr_00890|M.leprae_Br4923 GEFATAGRWDRIVVDCASTADVLRMLTLPSTVGLYVERAWPRHRRLSIAA
Mflv_2965|M.gilvum_PYR-GCK GELADSGEWDLVVVDCASTADAMRMLTLPATFALYLERAWPRHRRLS-SA
Mvan_3546|M.vanbaalenii_PYR-1 GELADSGQWDLVVVDCASTADAMRMLTLPATFSLYLERAWPRHRRLS-GV
MSMEG_4250|M.smegmatis_MC2_155 GELAESGQWDHVVVDCASTADALRMLTLPETFGLYLERAWPRHRRLS-GT
TH_1108|M.thermoresistible__bu AELAAAGRWDHVVVDCASTADALRMLTLPDTFNVYLERAWPRHRRLSTGI
MAB_1982|M.abscessus_ATCC_1997 QQLADTGEWDVVVVDCASTADALRMLTLPGTFAMYLERAWPRHRRLG-GV
::* : .** :*********.:****** *. :*:**********.
Mb2206c|M.bovis_AF2122/97 DDGRSAVLAELLERIRASVERLSTLLTDGALVSAHLVLTPERVVAAEAVR
Rv2184c|M.tuberculosis_H37Rv DDGRSAVLAELLERIRASVERLSTLLTDGALVSAHLVLTPERVVAAEAVR
MMAR_3228|M.marinum_M EDGRSAALVELLERTSASVDRLSTLLTDGSLVGAHLVLTPERVVAAEATR
MUL_3539|M.ulcerans_Agy99 EDGRSAALVELLERTSASVDRLSTLLTDGSLVGAHLVLTPERVVAAEATR
MAV_2310|M.avium_104 EDARSAAVVELLERVSASVEALSALLTDGDLVGAHLVLTPERVVAAEAAR
MLBr_00890|M.leprae_Br4923 GDAPSAAVVELLERISTSVERLGALLTDGSLVSAHLVLTPERVVAAEAVR
Mflv_2965|M.gilvum_PYR-GCK DDARTAVVVGLLERVGAGTEELGRLLTDGSRVSAHLVMTPERVVAAEAVR
Mvan_3546|M.vanbaalenii_PYR-1 DDVRSAAVVELLERIGAGTDRLDTLLTDGSRVSAHLVMTAERVVAAEAVR
MSMEG_4250|M.smegmatis_MC2_155 VDAATATIVALMERIDAGLRRVGSLLTDGSRVSAHLVLTPERVVAAEAAR
TH_1108|M.thermoresistible__bu DDPRSAAVVALVERLAAATERLSALLTDETLVSAHLVLTAERVVAAEAVR
MAB_1982|M.abscessus_ATCC_1997 GTPRALILAELLERIAASADRLAVLLSDAERVGAHLVLTPERVVVAEAIR
: :. *:** :. : **:* *.****:*.****.*** *
Mb2206c|M.bovis_AF2122/97 TLGSLALMGVRVEELLVNQLLVQDENYEYRSLPDHPAFHWYAERIGEQRA
Rv2184c|M.tuberculosis_H37Rv TLGSLALMGVRVEELLVNQLLVQDENYEYRSLPDHPAFHWYAERIGEQRA
MMAR_3228|M.marinum_M TLGSLALMGVRVEELLVNQVLVRDEAYEYRSLPDHPAFYWYAERISEQRA
MUL_3539|M.ulcerans_Agy99 TLGSLALMGVRVEELLVNQVLVRDEAYEYRSLPDHPAFYWYAERISEQRA
MAV_2310|M.avium_104 TLGSLALMGVRVEELIVNQVLLQDDSYEYRNLPEHPAFYWYTERIAEQQS
MLBr_00890|M.leprae_Br4923 TLGSLALMGIRVEELIVNQVLVRNKFYEYRSLLDHPVFCWYTERICEQRA
Mflv_2965|M.gilvum_PYR-GCK TLGALSLMGVQVAELIVNQVLVQDDSFEYQNLPAHPAFDWYSERISEQQA
Mvan_3546|M.vanbaalenii_PYR-1 TLGTLSLMGVQIAELIVNQVLVQDDSFEYRNLPAHPAFDWYSERISEQQA
MSMEG_4250|M.smegmatis_MC2_155 TLGSLALMGVEVAELLVNQILVQDDSFEYHNLPAHPAFDWYTERISEQQA
TH_1108|M.thermoresistible__bu TLGSLALLGVRVPELIVNQILVQDDSFEYQNLPQHPAFDWYAERIAEQRA
MAB_1982|M.abscessus_ATCC_1997 TVGALALMGVRIDQVIVNQVLIQDDSYEYHNLPDHPAFDWYMQRITDQSA
*:*:*:*:*:.: :::***:*:::. :**:.* **.* ** :** :* :
Mb2206c|M.bovis_AF2122/97 VLDDLDATIGDVALVLVPHLAGEPIGPKALGGLLDSARRRQGSAPPGPLQ
Rv2184c|M.tuberculosis_H37Rv VLDDLDATIGDVALVLVPHLAGEPIGPKALGGLLDSARRRQGSAPPGPLQ
MMAR_3228|M.marinum_M VLEELDATIGDVALVLVAHAAGEPIGPKALGGLLDGARRRRGSAPPGPLR
MUL_3539|M.ulcerans_Agy99 VLEELDATIGDVALVLVAHAAGEPIGPKALGGLLDGARRRRGSAPPGPLR
MAV_2310|M.avium_104 VLEELDAAIGEVALVLTPHLSGEPIGPKALGALLDAARRRGGAAPPGPLR
MLBr_00890|M.leprae_Br4923 VLDNLDSTIGDVALVVIPYLSGEPIGPKALAELLDVAHRRRGPAPMGPLR
Mflv_2965|M.gilvum_PYR-GCK VLNDLDSAIGDVALVMVPHLPGEPIGPKALGELLDAARRRDGSAPPGPVR
Mvan_3546|M.vanbaalenii_PYR-1 VLTELDRVIGDVQLVMVPHLSGEPIGAKALGELLECARSRGGSPPPGPLH
MSMEG_4250|M.smegmatis_MC2_155 VLDELDATIGDVSLVLVPHLAGEPIGPKALAELLEAARRRDGAPPPGPLK
TH_1108|M.thermoresistible__bu VLDELEAAIGDVALVLVPHLPGEPIGPKALAELLDSARRRDGSPPPQPLR
MAB_1982|M.abscessus_ATCC_1997 VLDEMGEAIGDVQMLLVPHLPREPIGPDALGELAESVRRRDGAKPPAPLA
** :: .**:* ::: .: . ****..**. * : .: * *. * *:
Mb2206c|M.bovis_AF2122/97 PIVDLESGSGLASIYRLRLALPQLDPGTLTLGRADDDLIVSAGGMRRRVR
Rv2184c|M.tuberculosis_H37Rv PIVDLESGSGLASIYRLRLALPQLDPGTLTLGRADDDLIVSAGGMRRRVR
MMAR_3228|M.marinum_M PIVDLESGSGLGSVYRLRLALPQLDPGSLTLGRADDDLIISAGGMRRRVR
MUL_3539|M.ulcerans_Agy99 PIVDLESGSGLGSVYRLRLALPQLDPGSLTLGRADDDLIISAGGMRRRVR
MAV_2310|M.avium_104 PTVDLESGTGLGSIYRMRLALPQLDPSALTLGRVDDDLIISAGGLRRRVR
MLBr_00890|M.leprae_Br4923 PIVDLESGSGLESVYRLRLALPQLDFAALTLGRVDDDLIISAGGTRCRVR
Mflv_2965|M.gilvum_PYR-GCK PVVDRESGSGLDAVYRLRLELPQVDPTALSLGRVDDDLIIGAGGMRRRVR
Mvan_3546|M.vanbaalenii_PYR-1 PIVDRESGTGLDAVYRLRLELPQLDSSALSLGRVDDDLIIGVGGMRRRVR
MSMEG_4250|M.smegmatis_MC2_155 PIVDRESGSGLEAVYRMRLELPQVDSAALTLGRVDDDLIIGVGAMRRRVR
TH_1108|M.thermoresistible__bu PVVDRESGSGLQAVYRLRLELPHVDPGALTLGRVDDDLIIGVGALRRRVR
MAB_1982|M.abscessus_ATCC_1997 TVVEHESGSGADTVYRLRLELPQIDPATLSLGRVGDDLVIGANGMRRRVR
. *: ***:* ::**:** **::* :*:***..***::.... * ***
Mb2206c|M.bovis_AF2122/97 LASVLRRCTVLDAHLRGGELTVRFRPNPEVWPT
Rv2184c|M.tuberculosis_H37Rv LASVLRRCTVLDAHLRGGELTVRFRPNPEVWPT
MMAR_3228|M.marinum_M LASVLRRCIVLDARLSGGELTVRFRPDPEVWPT
MUL_3539|M.ulcerans_Agy99 LASVLRRCIVLDARLSGGELTVRFRPDPEVWPT
MAV_2310|M.avium_104 LASVLRRCTVLDAHLRGSELTVRFRPDPEVWPK
MLBr_00890|M.leprae_Br4923 LASVLRRCMVLGAQLRGSELTVRFRPDPEVWPI
Mflv_2965|M.gilvum_PYR-GCK LASVLRRCTVIGAQLRGTELTVRFRPNPEVWPR
Mvan_3546|M.vanbaalenii_PYR-1 LASVLRRCIVIGAQLRGSELTVRFRPNPEVWPR
MSMEG_4250|M.smegmatis_MC2_155 LASVLRRCIVVDASLRGSQLTVRFRPNPEVWPV
TH_1108|M.thermoresistible__bu LASVLRRCLVLDAALRGNELTVRFRPNPEVWPT
MAB_1982|M.abscessus_ATCC_1997 LASVLRRCVVVDARLVGGELTIRFRADPEVWPT
******** *:.* * * :**:***.:*****