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VFHPRVVLASCPALPEGDGDDDGLVAALRHRGLHARWLSWDDPETLDADVVILRATWDYTERLPEFLSWT RSVRNLLNAPEIVEWNTDKRYLGDLARLGVPVVPTAFFAVGEEVQIPAGPGGRLDGEIVVKPAVGAGSAG ALRFSDRVGALAHAVALQGQGKAVLVQPYDPRIADGETALVFLGGEESHAFTKGPLLPPPGQSPAFDPSG TYAEETLWPADPDEQVWRVGRLAVWAVTRLFDIEPEDLLYARVDVIGGRDDPRLLELELVEPSLGFRQLA ADARAGAEREFALGVERALQRFGLGPLSHRST
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3107 | - | - | 100% (312) | hypothetical protein MSMEG_3107 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1490 | - | 6e-75 | 50.16% (311) | hypothetical protein Mb1490 |
| M. gilvum PYR-GCK | Mflv_3685 | - | 1e-122 | 69.35% (310) | hypothetical protein Mflv_3685 |
| M. tuberculosis H37Rv | Rv1455 | - | 6e-75 | 50.16% (311) | hypothetical protein Rv1455 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2755c | - | 1e-100 | 60.06% (313) | hypothetical protein MAB_2755c |
| M. marinum M | MMAR_2260 | - | 4e-67 | 46.13% (310) | hypothetical protein MMAR_2260 |
| M. avium 104 | MAV_3323 | - | 5e-24 | 55.66% (106) | hypothetical protein MAV_3323 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1856 | - | 1e-66 | 45.48% (310) | hypothetical protein MUL_1856 |
| M. vanbaalenii PYR-1 | Mvan_2725 | - | 1e-121 | 68.39% (310) | hypothetical protein Mvan_2725 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3685|M.gilvum_PYR-GCK -------MKLVRPDVFHPRIVLAGCRALPEGDGDDDGLVEALRARGLHAR
Mvan_2725|M.vanbaalenii_PYR-1 -------MTPARPDLFHPRIVFAGCPALPEGDGDDSGLVGALRARGLHAR
MSMEG_3107|M.smegmatis_MC2_155 --------------MFHPRVVLASCPALPEGDGDDDGLVAALRHRGLHAR
MAB_2755c|M.abscessus_ATCC_199 --MGRPDVRLGRPDIFHPRIVLAGCPQLVAGDGDDAELVAALRVRDLHAR
Mb1490|M.bovis_AF2122/97 -------MKLARPDVFHPRVVLAGWPQQPAGDGDDAGLVAALRHRGLHAG
Rv1455|M.tuberculosis_H37Rv -------MKLARPDVFHPRVVLAGWPQQPAGDGDDAGLVAALRHRGLHAG
MMAR_2260|M.marinum_M -------MKLARPDVFHPRVVLAGWPHQPAGDGDDAGLVAALRRRGLHAH
MUL_1856|M.ulcerans_Agy99 -------MKLARPDVFHPRVVLAGWPHQPAGDGDDAGLVAALRRRGLHAH
MAV_3323|M.avium_104 MCLSCPGMKLARPDVFHPRIVLAGR-------RDDPGLVSALRRRGLHAR
:****:*:*. ** ** *** *.***
Mflv_3685|M.gilvum_PYR-GCK WLAWDDPETLGADLVILRATWDYTERPEQFLAWAHRVSHLLNPVEVVGWN
Mvan_2725|M.vanbaalenii_PYR-1 WLSWDDPATLDADLVILRAAWDYIDRLDEFLDWTRRVAHLLNPPEVVAWN
MSMEG_3107|M.smegmatis_MC2_155 WLSWDDPETLDADVVILRATWDYTERLPEFLSWTRSVRNLLNAPEIVEWN
MAB_2755c|M.abscessus_ATCC_199 WLSWDDPEMTQADLVILRATWDYPERLDEFLTWAGSVRNVLNPLPVVRWN
Mb1490|M.bovis_AF2122/97 WLSWDDPEIVHADLVILRATRDYPARLDEFLAWTTRVANLLNSRPVVAWN
Rv1455|M.tuberculosis_H37Rv WLSWDDPEIVHADLVILRATRDYPARLDEFLAWTTRVANLLNSRPVVAWN
MMAR_2260|M.marinum_M WLSWDDPDVSGADLVILRATRDYARRLDEFVAWTGGVRNLLNPPAVVAWN
MUL_1856|M.ulcerans_Agy99 WLSWDDPDISGADLVILRATRDYARRLDEFVAWTGGVRNLLNPPAVVAWN
MAV_3323|M.avium_104 RLPWEDPETLHADLVIVRAGPDAARR-DEFLAWTGRPRHVLNPPAALAWN
*.*:** **:**:** * * :*: *: ::**. : **
Mflv_3685|M.gilvum_PYR-GCK TDKRYLSDLAAAGVPVVPSAFFEPGEQVRIPDG-------EVVVKPAVGA
Mvan_2725|M.vanbaalenii_PYR-1 TDKRYLADLAAAGVPTVPSAFFAPGQPVRIPAG-------EVVVKPSVGA
MSMEG_3107|M.smegmatis_MC2_155 TDKRYLGDLARLGVPVVPTAFFAVGEEVQIPAGPGGRLDGEIVVKPAVGA
MAB_2755c|M.abscessus_ATCC_199 IDKRYLNDLAAAGIPTVPSMFFAPDEPIVLPDG-------ELVIKPAVAG
Mb1490|M.bovis_AF2122/97 VERRYLRDLMDRGVPTVPGEVYVPGEPVRLPRKG------QVFVGPTIGT
Rv1455|M.tuberculosis_H37Rv VERRYLRDLMDRGVPTVPGEVYVPGEPVRLPRKG------QVFVGPTIGT
MMAR_2260|M.marinum_M THRRYLDDLANRGVPTLPSQMCRPGERLRSLPAP------QVFVGPGVGT
MUL_1856|M.ulcerans_Agy99 AHRRYLDDLANRGVPTLPSQMCRPGERLRSLPAP------QVFIGPGVGT
MAV_3323|M.avium_104 LDAHYLRDLRDGGVPTRP--------------------------------
. :** ** *:*. *
Mflv_3685|M.gilvum_PYR-GCK GSVGAERFSDPTHAHAHAAALQAAGRTALVQPYDARIGD-GETALVFLAG
Mvan_2725|M.vanbaalenii_PYR-1 GSVGALRFSDSLQARAHAEALQDAGRTALVQPYDARVGA-GETALVFLGG
MSMEG_3107|M.smegmatis_MC2_155 GSAGALRFSDRVGALAHAVALQGQGKAVLVQPYDPRIAD-GETALVFLGG
MAB_2755c|M.abscessus_ATCC_199 GSRGAGRFTCPEAARNHAEALQDEGRTVLIQPYDPRVDQHGETALVFLNG
Mb1490|M.bovis_AF2122/97 GTR---RCSAR-FAAEFVAQLHAAGQAVLVQPGGS----GDETVLVFLGG
Rv1455|M.tuberculosis_H37Rv GTR---RCSAR-FAAEFVAQLHAAGQAVLVQPGGS----GDETVLVFLGG
MMAR_2260|M.marinum_M GTR---RFSDHAKAAEYVDELHAAGQSALVHVGDP----VPEAVLIFVGG
MUL_1856|M.ulcerans_Agy99 GTR---RFSDHAKAAEYVDELHAAGQSALVHVGDP----VPEAVLIFVGG
MAV_3323|M.avium_104 ---------------------------------GA----QPETSLIFLGG
.. *: *:*: *
Mflv_3685|M.gilvum_PYR-GCK EQSHAFTKGPMLPPPGETPAFDASGTYAEERLAPADPDFELWDLGHRALG
Mvan_2725|M.vanbaalenii_PYR-1 QQSHAFTKGPMLPSPGERPVFDESGTYAEEQLRPADPDFELWDVGHAALA
MSMEG_3107|M.smegmatis_MC2_155 EESHAFTKGPLLPPPGQSPAFDPSGTYAEETLWPADPDEQVWRVGRLAVW
MAB_2755c|M.abscessus_ATCC_199 EPSHAFTKAALLPPPGTAAEVDESGLFHSERLAPVKPTSALWRLGAAALA
Mb1490|M.bovis_AF2122/97 EPSHAFTK-------------------QADTWRQTEPDFEIWDVGAAAVA
Rv1455|M.tuberculosis_H37Rv EPSHAFTK-------------------QADTWRQTEPDFEIWDVGAAAVA
MMAR_2260|M.marinum_M RPSHAFTT-------------------QENALRQGEPDFEIWDIGAAALR
MUL_1856|M.ulcerans_Agy99 RPSHAFTT-------------------QENALRQGEPDFEIWDIGAAALR
MAV_3323|M.avium_104 AQSHAWP---------------------------AEPEFESWDLGHAALA
***:. .* * :* *:
Mflv_3685|M.gilvum_PYR-GCK AAADHLGLQTSDFLYARVDVVG--GPDDPRLLELELVEPSLGWRQLPDGD
Mvan_2725|M.vanbaalenii_PYR-1 AAAGHLGLASSDLLYARVDLLG--DADDPRLLELELVEPSLGWCQLGADV
MSMEG_3107|M.smegmatis_MC2_155 AVTRLFDIEPEDLLYARVDVIG--GRDDPRLLELELVEPSLGFRQLAADA
MAB_2755c|M.abscessus_ATCC_199 AAATQCGVAMTDLLYARVDVIGGVADDDPRLLELELVEPSLGWRQLETEE
Mb1490|M.bovis_AF2122/97 GAAAQVGVDPGELLYARAHITGG--SRDPRLLELQLVDPSLGWQWLDPDI
Rv1455|M.tuberculosis_H37Rv GAAAQVGVDPGELLYARAHITGG--SRDPRLLELQLVDPSLGWQWLDPDI
MMAR_2260|M.marinum_M AAAAAAGVQVGELLCARAHLVG------TRLLELQLIDPSLGWRRLDTAT
MUL_1856|M.ulcerans_Agy99 AAAAAAGVQAGELLCARAHLVG------TRLLELQLIDPSLGWRRLDTAT
MAV_3323|M.avium_104 VAADHTGIGVPELLFARADLAG------DRLVRLDLVAPELGWRHLDTPG
.: .: ::* **..: * **:.*:*: *.**: *
Mflv_3685|M.gilvum_PYR-GCK RARQQRRFALAVESALERFGLGPFAHRRP-
Mvan_2725|M.vanbaalenii_PYR-1 RRRQERRFALEVESALERFGLGPFAHRRP-
MSMEG_3107|M.smegmatis_MC2_155 RAGAEREFALGVERALQRFGLGPLSHRST-
MAB_2755c|M.abscessus_ATCC_199 RDLAQRKFVIGVEDALERLGLGPLGQRGRG
Mb1490|M.bovis_AF2122/97 RNLAQRDFALCVQSALERLGLGPFSHRRP-
Rv1455|M.tuberculosis_H37Rv RNLAQRDFALCVQSALERLGLGPFSHRRP-
MMAR_2260|M.marinum_M RDRAQREFALSVQSALGGLGLGPFSHRRP-
MUL_1856|M.ulcerans_Agy99 RDRAQREFALSVQSALGGLGLGPFSHRRP-
MAV_3323|M.avium_104 REAAQRRFALAVESACERLGLGPLSHRRP-
* :* *.: *: * :****:.:*