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MTRFIDISMSLENDVPADPPGYEFSIEYTSHQDTLPMLQRRYDGLQPEELPNAEAFALETVHLSTHNGTH VDAPWHYSSMMEDGSRPRTIDEMPLDWFLRPAVKLDFRHLDDGYVATAADVQGELKRIGYTLRPLDIVVV NTSAGAKFGTPEYPQSGCGLGREATLWLCDQGVRVVGTDAWSWDAPFSYVAERYARDRDASIIWEGHKAG RRTEYCQIEKLRHLDQLPDHGFTIACFPVKIHAASAGWTRAVAMIDDTNGAN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2947 | - | - | 100% (262) | polyketide cyclase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1744 | - | 3e-10 | 33.33% (150) | hypothetical protein Mb1744 |
| M. gilvum PYR-GCK | Mflv_1005 | - | 5e-89 | 57.09% (261) | cyclase family protein |
| M. tuberculosis H37Rv | Rv1716 | - | 3e-10 | 33.33% (150) | hypothetical protein Rv1716 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4492c | - | 3e-06 | 28.67% (150) | hypothetical protein MAB_4492c |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1744|M.bovis_AF2122/97 MTFAWPLGAAESTLEFYDLSHPWGHGAPAWPYFEDVQIERLHGMAKSRVL
Rv1716|M.tuberculosis_H37Rv MTFAWPLGAAESTLEFYDLSHPWGHGAPAWPYFEDVQIERLHGMAKSRVL
MAB_4492c|M.abscessus_ATCC_199 ------MG-----LQFYDLSHPWGLGTPCWPYFEDVKIERLHNMARSGVL
MSMEG_2947|M.smegmatis_MC2_155 ------------MTRFIDISMSLENDVPADPPGYEFSIEYTSHQDTLPML
Mflv_1005|M.gilvum_PYR-GCK ------------MRTLIDISVPLRGGIASDPPGLRPEIEYLTHRDTVGDV
: *:* . . .. * .** :
Mb1744|M.bovis_AF2122/97 T-------------------QKITTVMHSGTHIDAPAHVVEGTP------
Rv1716|M.tuberculosis_H37Rv T-------------------QKITTVMHSGTHIDAPAHVVEGTP------
MAB_4492c|M.abscessus_ATCC_199 T-------------------QKITTVMHSGTHIDAPAHVVPGTP------
MSMEG_2947|M.smegmatis_MC2_155 QRRYDGLQPEELPNAEAFALETVHLSTHNGTHVDAPWHYSSMM-----ED
Mflv_1005|M.gilvum_PYR-GCK LSFFPGATEDDLPDGEGWAIERVSMTTHCGTHLDAPYHFASTMNMASVKN
: : * ***:*** *
Mb1744|M.bovis_AF2122/97 -----FLDEIPLSAFFGTGVVVSIPKGKWGMVT-----AEDLQNATPDIR
Rv1716|M.tuberculosis_H37Rv -----FLDEIPLSAFFGTGVVVSIPKGKWGMVT-----AEDLQNATPDIR
MAB_4492c|M.abscessus_ATCC_199 -----FLEEVPLPNFFGTGVVVSIPKKKWEVIT-----AEDLENARPQIR
MSMEG_2947|M.smegmatis_MC2_155 GSRPRTIDEMPLDWFLRPAVKLDFRHLDDGYVATAADVQGELKRIGYTLR
Mflv_1005|M.gilvum_PYR-GCK GERAITIDEVPLEWCFQPGVKLDFRHLDDGYVVTPDDIDAELSRIGHTLS
::*:** : ..* :.: : . :. :*.. :
Mb1744|M.bovis_AF2122/97 PGDIVVVNTGWHHKYADSAEYYAYSPGFDKKAGEWFAAKGVKAVGTDTQA
Rv1716|M.tuberculosis_H37Rv PGDIVVVNTGWHHKYADSAEYYAYSPGFDKKAGEWFAAKGVKAVGTDTQA
MAB_4492c|M.abscessus_ATCC_199 EGDIVIVNTGWHRYYGDNRHYYAYAPGFYKDAGEWFVERKVKMVGSDTQA
MSMEG_2947|M.smegmatis_MC2_155 PLDIVVVNTSAGAKFG-TPEYPQSGCGLGREATLWLCDQGVRVVGTDAWS
Mflv_1005|M.gilvum_PYR-GCK PLEIVVVNTSAGTRYG-HDDYVQRGCGIGRDATLHMLEQGVRLTGTDAWS
:**:***. :. .* . *: :.* : : *: .*:*: :
Mb1744|M.bovis_AF2122/97 LDHPLATAIAPHGPAEAQGGLLPWAVREYEAQTGRKVLDDFPDWEPCHRA
Rv1716|M.tuberculosis_H37Rv LDHPLATAIAPHSPAEAQGGLLPWAVREYEAQTGRKVLDDFPDWEPCHRA
MAB_4492c|M.abscessus_ATCC_199 LDHPLGTAIGPHG-TGAPNGLIPQVNLEYEQLTGRKVIEDFPYWEPCHNA
MSMEG_2947|M.smegmatis_MC2_155 WDAPFS----------------------YVAERYARDRDASIIWEG-HKA
Mflv_1005|M.gilvum_PYR-GCK WDAPFS----------------------YTARRYAETHDASLIWEG-HRA
* *:. * . : ** *.*
Mb1744|M.bovis_AF2122/97 ILSQGIYGFENVGGDLDKVTGKRVTFAAFPWRWVGGDGCIVRLVAIVDPT
Rv1716|M.tuberculosis_H37Rv ILSQGIYGFENVGGDLDKVTGKRVTFAAFPWRWVGGDGCIVRLVAIVDPT
MAB_4492c|M.abscessus_ATCC_199 ILSNGILGFENVGGDIDKVTGKRVTFAAFPWRWKKGDGCIVRLVAITDPT
MSMEG_2947|M.smegmatis_MC2_155 GRRTEYCQIEKLR-HLDQLPDHGFTIACFPVKIHAASAGWTRAVAMIDDT
Mflv_1005|M.gilvum_PYR-GCK GRDIGYCHLEKLH-NLEQLPATGFQVSCFPVKVHEASAGWTRAVAIIDGA
:*:: .::::. . .:.** : ... .* **: * :
Mb1744|M.bovis_AF2122/97 GSYRIETGKAA
Rv1716|M.tuberculosis_H37Rv GSYRIETGKAV
MAB_4492c|M.abscessus_ATCC_199 GEYRIETGTAG
MSMEG_2947|M.smegmatis_MC2_155 NGAN-------
Mflv_1005|M.gilvum_PYR-GCK HIR--------