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M. smegmatis MC2 155 MSMEG_2630 (-)

annotation: DHH family protein
coordinates: 2711052 - 2712074
length: 340

MPVTTTDPKTGLLTGPDAQIAGARVDARGAADLLTAASSVSVICHVYPDADTIGAGLALAQVLAASGKHV
EVSFATPAQLPESLQSLPGGHLLVAPEAMRRDADLVVTVDIPSINRLGALSGLAGPGREVLVIDHHASNQ
LFGTANYIDPSADSTTMLVAELLDAWGKPIDEKVAHCLYAGLTTDTGSFRWATARAHRLAARLVELGVDN
ASISRTLLDTHPFAWLPMLSRVLATARLLPDALDGRGFVYAVVPHDEWSEARPEEVESIVDIVRTTQQAE
VAAVFKEIEPMHWSVSMRAKSVNLASVASAFGGGGHPHAAGYSATGSADDVVQALARALG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2630--100% (340)DHH family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2862c-1e-13973.08% (338) hypothetical protein Mb2862c
M. gilvum PYR-GCKMflv_4037-1e-13176.74% (301) phosphoesterase domain-containing protein
M. tuberculosis H37RvRv2837c-1e-13973.08% (338) hypothetical protein Rv2837c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3129c-1e-12067.08% (319) hypothetical protein MAB_3129c
M. marinum MMMAR_1896-1e-13074.38% (320) hypothetical protein MMAR_1896
M. avium 104MAV_3691-1e-13073.82% (317) DHH family protein
M. thermoresistible (build 8)TH_2382-1e-13773.08% (338) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_2124-1e-12974.53% (318) hypothetical protein MUL_2124
M. vanbaalenii PYR-1Mvan_2316-1e-13876.54% (324) phosphoesterase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_2630|M.smegmatis_MC2_155      --MPVTTTDPKTGLLTGPDAQIAGARVDARGAADLLTAASSVSVICHVYP
TH_2382|M.thermoresistible__bu      ----VTTTD-------ATDDRPVGVRVGAAEAAAELSAAQSVSVVCHVHP
Mflv_4037|M.gilvum_PYR-GCK          -----------------------------------------MSIVCHVFP
Mvan_2316|M.vanbaalenii_PYR-1       MAPTRSMTDS------TTDALITGARVDACAAADLLASARTVSVVCHVFP
Mb2862c|M.bovis_AF2122/97           ------MTTIDPRSELVDGRRRAGARVDAVGAAALLSAAARVGVVCHVHP
Rv2837c|M.tuberculosis_H37Rv        ------MTTIDPRSELVDGRRRAGARVDAVGAAALLSAAARVGVVCHVHP
MMAR_1896|M.marinum_M               -------------------MRCPGVRVDAVGAAELLSAADSIAVIAHVHP
MUL_2124|M.ulcerans_Agy99           ------------------------MRVDAVGAAELLSAADSIAVIAHVHP
MAV_3691|M.avium_104                --------------------------MDAHGAVELLSRAGTVAVIAHVHP
MAB_3129c|M.abscessus_ATCC_199      ------------MSAVPIETGAVGARVDEDGAVALLAKASRVVIICHVHP
                                                                             : ::.**.*

MSMEG_2630|M.smegmatis_MC2_155      DADTIGAGLALAQVLAASGKHVEVSFATPAQLPESLQSLPGGHLLVAPEA
TH_2382|M.thermoresistible__bu      DADTIGAGLALAQVLDRIGIAVEVGFAAPAELPESLQSLPGGRLLVPPHR
Mflv_4037|M.gilvum_PYR-GCK          DADTIGAGLALALVLDEAGKSVEVSFAEPDTLPDSLRSLPGGHLLVPPAT
Mvan_2316|M.vanbaalenii_PYR-1       DADTIGAGLALALVLEQSGKRVQVGFAEPDKLPESLLTLPGGHLLVAPQD
Mb2862c|M.bovis_AF2122/97           DADTIGAGLALALVLDGCGKRVEVSFAAPATLPESLRSLPGCHLLVRPEV
Rv2837c|M.tuberculosis_H37Rv        DADTIGAGLALALVLDGCGKRVEVSFAAPATLPESLRSLPGCHLLVRPEV
MMAR_1896|M.marinum_M               DADTIGAGLALALVLDGCGKQVEVSFAAPATLPESLASLPGCALLVDADE
MUL_2124|M.ulcerans_Agy99           DADTIGAGLALALVLDGCGKQVEVSFAAPATLPESLASLPGCALLVDADE
MAV_3691|M.avium_104                DADTIGAGLALGLVLDKCGKRVEVSFAEPAGLPESLASLPGCRLLVRPDE
MAB_3129c|M.abscessus_ATCC_199      DADTVGSGLALGQALVAKGVDVQVSFGEPAAPPESVGTLPGAHLLVRPQE
                                    ****:*:****. .*   *  *:*.*. *   *:*: :***  *** .  

MSMEG_2630|M.smegmatis_MC2_155      MRRDADLVVTVDIPSINRLGALSGLAGPGREVLVIDHHASNQLFGTANYI
TH_2382|M.thermoresistible__bu      LRRDADLVVTVDIPSVHRLGELRTMVDPGRRVLVIDHHASNELFGTVNYV
Mflv_4037|M.gilvum_PYR-GCK          MRRDADLVVTVDIPSVNRLGALRDLADGDRDVLVIDHHASNQLFGTANLV
Mvan_2316|M.vanbaalenii_PYR-1       MRRDADLVVTVDIPSVNRLGGLRDLAESDH-VLVIDHHASNHLFGTANFV
Mb2862c|M.bovis_AF2122/97           MRRDVDLVVTVDIPSVDRLGALGDLTDSGRELLVIDHHASNDLFGTANFI
Rv2837c|M.tuberculosis_H37Rv        MRRDVDLVVTVDIPSVDRLGALGDLTDSGRELLVIDHHASNDLFGTANFI
MMAR_1896|M.marinum_M               MRRDVDLVVTVDVPSIKRLGGLSDLADPGRSVLVIDHHASNAEFGTANFI
MUL_2124|M.ulcerans_Agy99           MRRDVDLVVTVDVPSIKRLGGLSDLADPGRSVLVIDHHASNAEFGTANFI
MAV_3691|M.avium_104                IRRDADLVVTVDVPSVKRLGVLSELAVTGREVLVIDHHASNDVFGTANFI
MAB_3129c|M.abscessus_ATCC_199      LRRDPDLVVTVDSPSVRRLGQLAQLTEGSTPVLVIDHHVSNELFGTANYV
                                    :*** ******* **: *** *  :.  .  :******.**  ***.* :

MSMEG_2630|M.smegmatis_MC2_155      DPSADSTTMLVAELLDAWGKPIDEKVAHCLYAGLTTDTGSFRWATARAHR
TH_2382|M.thermoresistible__bu      DETADSTTLLVAELLDAWDQPIDTAVAHCLYAGLITDTGSFRWASPRAHR
Mflv_4037|M.gilvum_PYR-GCK          DAGADSTTMLVAELLDAWDKPLGLDVAHCLYAGLTTDTGSFRWASARAHR
Mvan_2316|M.vanbaalenii_PYR-1       DPAADSTTMLVADLLDAWHKPIDLGVAHCLYAGLTTDTGSFRWASARAHR
Mb2862c|M.bovis_AF2122/97           DPSADSTTTMVAEILDAWGKPIDPRVAHCIYAGLATDTGSFRWASVRGYR
Rv2837c|M.tuberculosis_H37Rv        DPSADSTTTMVAEILDAWGKPIDPRVAHCIYAGLATDTGSFRWASVRGYR
MMAR_1896|M.marinum_M               DCSADSTTMMVAEILDAWGKPIDLDVAHCIYAGLTTDTGSFRWASPRGLR
MUL_2124|M.ulcerans_Agy99           DCSADSTTMMVAEILDAWGKPIDLDVAHCVYAGLTTDTGSFRWASPRGLR
MAV_3691|M.avium_104                DVAADSTTMMIADILDAWGKPIDPDVAHCIYAGLTTDTGSFRWASARALR
MAB_3129c|M.abscessus_ATCC_199      DIAADSTTMMVVQLLDAWGVDITPEMAHCLYAGLVTDSGSFRWATPRGHR
                                    *  ***** ::.::****   :   :***:**** **:******: *. *

MSMEG_2630|M.smegmatis_MC2_155      LAARLVELGVDNASISRTLLDTHPFAWLPMLSRVLATARLLPDALDGRGF
TH_2382|M.thermoresistible__bu      LAARLVELGVDNAAVSRRLLDTHPFSWLPMLSRVLASARLLEGVGDGHGL
Mflv_4037|M.gilvum_PYR-GCK          LAARLVEAGVDNAAVSRTLMDTHPFAWLPMLSRVLGSAELVADAVGGRGF
Mvan_2316|M.vanbaalenii_PYR-1       LAARLLEIGVDNAAISRTLLDTHPFAWLPMLSRVLGSARLDADAAGGRGL
Mb2862c|M.bovis_AF2122/97           LAARLVEIGVDNATVSRTLMDSHPFTWLPLLSRVLGSAQLVSEAVGGRGL
Rv2837c|M.tuberculosis_H37Rv        LAARLVEIGVDNATVSRTLMDSHPFTWLPLLSRVLGSAQLVSEAVGGRGL
MMAR_1896|M.marinum_M               LAARLVDIGVDNAAISRSLMDTHPFMWLPMLSRVLGSAQLLPEAVAGRGL
MUL_2124|M.ulcerans_Agy99           LAARLVDIGVDNAAISRSLMDTHPFMWLPMLSRVLGSAQLLPEAVAGRGL
MAV_3691|M.avium_104                LAARLVDIGVDNAAISRALMDTHPFGWLPLLSRVLASAQLLPDAVGGRGL
MAB_3129c|M.abscessus_ATCC_199      LAARLLDLGADGVNITRTFMDSHPFVWLPILSRVLGTAELVPHAVGGAGM
                                    *****:: *.*.. ::* ::*:*** ***:*****.:*.*   .  * *:

MSMEG_2630|M.smegmatis_MC2_155      VYAVVPHDEWSEARPEEVESIVDIVRTTQQAEVAAVFKEIEPMHWSVSMR
TH_2382|M.thermoresistible__bu      VYAVVPHEEWAKARPEEVESIVDIVRTTEEADVAAVFKEVEPRQWSVSMR
Mflv_4037|M.gilvum_PYR-GCK          VYAIVGHDEWANARSEEVESIIDIVRTTAQAEVAAVLKEIEPQRWSASLR
Mvan_2316|M.vanbaalenii_PYR-1       VYAVVDHSEWTAARSEEIESIVDIVRTTQQAEVAAVFKEIGPGRWSVSMR
Mb2862c|M.bovis_AF2122/97           VYVVVDNREWVAARSEEVESIVDIVRTTQQAEVAAVFKEVEPHRWSVSMR
Rv2837c|M.tuberculosis_H37Rv        VYVVVDNREWVAARSEEVESIVDIVRTTQQAEVAAVFKEVEPHRWSVSMR
MMAR_1896|M.marinum_M               VYAVVEHQEFVRARAEEVESIVDIVRTTRQAEVAVVFKEVDPQQWSVSMR
MUL_2124|M.ulcerans_Agy99           VYAVVEHQEFVRARAEEVESIVDIVRTTRQAEVAVVFKEVDPQQWSVSMR
MAV_3691|M.avium_104                VYAVVGNQDWISSRPEEVESIVDIVRTTQQAEVAAVFKEIAPGQWSVSMR
MAB_3129c|M.abscessus_ATCC_199      VYAVVTHDVWSRARTEEVESIVDIVRTTTEAEVAVVFKEIEPEHWSVSMR
                                    **.:* :  :  :*.**:***:****** :*:**.*:**: * :**.*:*

MSMEG_2630|M.smegmatis_MC2_155      AKS-VNLASVASAFGGGGHPHAAGYSATGSADDVVQALARALG
TH_2382|M.thermoresistible__bu      SKS-LDLVAVASGFGGGGHRQAAGYSTAGSVDDVVQALIAALG
Mflv_4037|M.gilvum_PYR-GCK          SKS-VDVSAVAATFGGGGHRLAAGFTATGSADDVVAALRTALG
Mvan_2316|M.vanbaalenii_PYR-1       SKS-LDVSTVASAFGGGGHRLAAGYSASGTADDLIASLRTALG
Mb2862c|M.bovis_AF2122/97           AKT-VNLAAVASGFGGGGHRLAAGYTTTGSIDDAVASLRAALG
Rv2837c|M.tuberculosis_H37Rv        AKT-VNLAAVASGFGGGGHRLAAGYTTTGSIDDAVASLRAALG
MMAR_1896|M.marinum_M               AKKDIDLSVVASAFGGGGHLLAAGYSTTGSIDDVVASLLAALG
MUL_2124|M.ulcerans_Agy99           AKKDIDLSVVASAFGGGGHLLAAGYSTTGSIDDVVASLLAALG
MAV_3691|M.avium_104                AKAQVDLAAVASGFGGGGHRLAAGYSTTGSIEDAVASLRAALG
MAB_3129c|M.abscessus_ATCC_199      ARSAVDLSAVAATFDGGGHRLAAGFSATGPVDDVVAALVRALD
                                    ::  :::  **: *.****  ***::::*. :* : :*  **.