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M. smegmatis MC2 155 MSMEG_2349 (-)

annotation: glycosyl hydrolase, family protein 57
coordinates: 2430027 - 2431571
length: 514

TDASAEPVPGLFTLVLHTHLPWLAHHGRWPVGEEWLYQSWAAAYLPLVRVLRTLAAEGRSHLISLGMTPV
VTAQLDDPYCLTGMHHWLANWQLRALEATTLRDRKGLREFGSHELSLAAEAMEDFTTHWRHGASPLLREL
IDAETIELLGGPLSHPFQPLLNPRLREFALREGLADSQHRFAHTPTGIWAPECAYAPGMETGYGAAGVGH
FMVDGPSLHGDTALGRPVGESDVIAFGRDLQVSYRVWSPKSGYPGHGAYRDFHTYDHTTGLKPARVTGRN
VPSEQKAPYEPERADRAVDVHVADFVEVVRRRLLDESQRIGRPAHVVAAFDTELFGHWWHEGPVWLERVL
RALPQAGVRVGTLADAAADGFVGTPVELPPSSWGSGKDWQVWSGQKVADLVQLNSEVVDNALATVDKALT
QHATVGSPVTRDRVADQILRETLLTVSSDWPFMVSKDSAAEYARYRAHLHAHATREISDALAAGRREQAE
RLADGWNKADGLFGALDARRLPR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2349--100% (514)glycosyl hydrolase, family protein 57

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3057-0.080.19% (525) hypothetical protein Mb3057
M. gilvum PYR-GCKMflv_4261-0.081.17% (515) glycoside hydrolase family protein
M. tuberculosis H37RvRv3031-0.080.19% (525) hypothetical protein Rv3031
M. leprae Br4923MLBr_01714-0.076.78% (521) hypothetical protein MLBr_01714
M. abscessus ATCC 19977MAB_3365-0.075.58% (520) hypothetical protein MAB_3365
M. marinum MMMAR_1682-0.079.92% (523) hypothetical protein MMAR_1682
M. avium 104MAV_3878-0.076.74% (533) glycosyl hydrolase, family protein 57
M. thermoresistible (build 8)TH_2192-0.083.89% (509) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_1920-0.079.92% (523) hypothetical protein MUL_1920
M. vanbaalenii PYR-1Mvan_2097-0.081.35% (520) glycoside hydrolase family protein

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_2349|M.smegmatis_MC2_155      ------MT--DASAEPVPGLFTLVLHTHLPWLAHHGRWPVGEEWLYQSWA
TH_2192|M.thermoresistible__bu      ------MTGGADSPDPVPGLFTLVLHTHLPWLAHHGRWPVGEEWLYQSWS
Mflv_4261|M.gilvum_PYR-GCK          MSHADVVS--GDENSSVPGLFTLVLHTHLPWLAHHGRWPVGEEWLYQSWS
Mvan_2097|M.vanbaalenii_PYR-1       MSGANKVQKREADAEPVPGLFTLVLHTHLPWLAHHGRWPVGEEWLYQSWS
Mb3057|M.bovis_AF2122/97            ---------MNTSASPVPGLFTLVLHTHLPWLAHHGRWPVGEEWLYQSWA
Rv3031|M.tuberculosis_H37Rv         ---------MNTSASPVPGLFTLVLHTHLPWLAHHGRWPVGEEWLYQSWA
MLBr_01714|M.leprae_Br4923          ---------MNTSANPVPGLFTLVLHTHLPWLAHHGRWPVGEEWLYQSWA
MAV_3878|M.avium_104                ---------MNSSHDRVPGLFTLVLHTHLPWLAHHGRWPVGEEWLYQSWA
MMAR_1682|M.marinum_M               ----MTNWDNTNSPDRVPGLFTLVLHTHLPWLAHHGRWPVGEEWLYQSWS
MUL_1920|M.ulcerans_Agy99           ----MTHWDNTNSPDRVPGLFTLVLHTHLPWLAHHGRWPVGEEWLYQSWS
MAB_3365|M.abscessus_ATCC_1997      ---------MTPSKKPVPGLFTMVLHTHLPWLANHGRWPVGEEWLYQSWS
                                                . . ******:**********:***************:

MSMEG_2349|M.smegmatis_MC2_155      AAYLPLVRVLRTLAAEGRSHLISLGMTPVVTAQLDDPYCLTGMHHWLANW
TH_2192|M.thermoresistible__bu      ATYLPVLRVLRTLADEGRHHVLTLGVTPVVAAQLDDPYCLTGMHHWLANW
Mflv_4261|M.gilvum_PYR-GCK          AAYLPLIRVLRTLAAENRRHLITLGITPVVAAQLDDPYCLQGMNHWLANW
Mvan_2097|M.vanbaalenii_PYR-1       ACYLPLVRVLRTLAAENRRHLITLGVTPVVAAQLDDPYCLQGMQHWLANW
Mb3057|M.bovis_AF2122/97            AAYLPLLQVLAALADENRHRLITLGMTPVVNAQLDDPYCLNGVHHWLANW
Rv3031|M.tuberculosis_H37Rv         AAYLPLLQVLAALADENRHRLITLGMTPVVNAQLDDPYCLNGVHHWLANW
MLBr_01714|M.leprae_Br4923          AAYLPLLQVLHTLADENRHRLITLGVTPVVNAQLDDPYCLDGMHHWLANW
MAV_3878|M.avium_104                AAYLPLLRVLDTLAGEDRRGLLTLGVTPVVNAQLDDPYCLDGMHHWLANW
MMAR_1682|M.marinum_M               AAYLPLFRVLRTLADEGRRGLITLGMTPVVNAQLDDPYCLDGMHHWLANW
MUL_1920|M.ulcerans_Agy99           AAYLPLFRVLRTLADEGRRGLITLGMTPVVNAQLDDPYCLDGMHHWLANW
MAB_3365|M.abscessus_ATCC_1997      AAYLPLFKVLRTLAAEGRENLLTLGITPVVAAQLDDPHCLTGLHSWLANW
                                    * ***:.:** :** *.*  :::**:**** ******:** *:: *****

MSMEG_2349|M.smegmatis_MC2_155      QLRALEATTLRDRK-------------GLREFGSHELSLAAEAMEDFTTH
TH_2192|M.thermoresistible__bu      QLRALEATTLGDP---------------LRAFGRHEYARAERALEEFDTR
Mflv_4261|M.gilvum_PYR-GCK          QLRALEASTTRSSEPGAP---PASQPQALRQFGVREYDEAERELGEFDAL
Mvan_2097|M.vanbaalenii_PYR-1       QLRAVEAATMRTAS-GAS---PASEPKALRQFGSREHTEAERELAEFDAL
Mb3057|M.bovis_AF2122/97            QLRAEEAASVRYARQSKSADYPSCTPEALRAFGIRECADAARALDNFATR
Rv3031|M.tuberculosis_H37Rv         QLRAEEAASVRYARQSKSADYPSCTPEALRAFGIRECADAARALDNFATR
MLBr_01714|M.leprae_Br4923          RLRATEAASVRSGSESK----PACAPQALRAFGARECIEAQRALEYFATL
MAV_3878|M.avium_104                RLRAMEAASVRSAPRSKSAGYQACTPEALRALGIRESAEAERALDDFATR
MMAR_1682|M.marinum_M               RLRAAEATSVRSSPASKSAKHLSCTPEALRDFGTRECAEADQALDDFATA
MUL_1920|M.ulcerans_Agy99           RLRAAEATSVRSAPASKSAKHLSCTPEALRDFGTRECAEADQALDDFAAA
MAB_3365|M.abscessus_ATCC_1997      QLRAFEASTISSTDAEPG---TASSPEMLRAFGVREYQTATAALDEFDTY
                                    :*** **::                   ** :* :*   *   :  * : 

MSMEG_2349|M.smegmatis_MC2_155      WRHGASPLLRELIDAETIELLGGPLSHPFQPLLNPRLREFALREGLADSQ
TH_2192|M.thermoresistible__bu      WRHGASPLLRELIDAGTIELLGGPLTHPFQPLLHPRLREFALREGLADAG
Mflv_4261|M.gilvum_PYR-GCK          WRHGASPVFRELLDSQTIELLGGPLAHPFQPLLNPRLREFALREGLADAH
Mvan_2097|M.vanbaalenii_PYR-1       WRHGASPALRELLDGEVIELLGGPLAHPFQPLLNPRLREFALREGLADAA
Mb3057|M.bovis_AF2122/97            WRHGGSPLLRGLIDAGTVELLGGPLAHPFQPLLAPRLREFALREGLADAQ
Rv3031|M.tuberculosis_H37Rv         WRHGGSPLLRGLIDAGTVELLGGPLAHPFQPLLAPRLREFALREGLADAQ
MLBr_01714|M.leprae_Br4923          WRHGGSPLLRSLIDAGTVELLGGPLAHPFQPLIAPRLREFALHEGLDDAW
MAV_3878|M.avium_104                WRHGGSPLLRRLLDAGTVELLGGPLAHPFQPLLAPRLREFALREGLADAA
MMAR_1682|M.marinum_M               WRHGASPLLRALLDAGTVELLGGPLAHPFQPLLNPRLREFALREGLADAR
MUL_1920|M.ulcerans_Agy99           WRHGASPLLRALIDAGTVELLGGPLAHPFQPLLNPRLREFALREGLADAR
MAB_3365|M.abscessus_ATCC_1997      WRHGGSGPLRNLIDAKAIELLGGPLAHPFQPLLHPRLREFALREGLADAA
                                    ****.*  :* *:*. .:*******:******: ********:*** *: 

MSMEG_2349|M.smegmatis_MC2_155      HRFAHT----PTGIWAPECAYAPGMETGYGAAGVGHFMVDGPSLHGDTAL
TH_2192|M.thermoresistible__bu      LRFGHT----PAGIWAPECAYAPGMETGYAAANVSHFMVDGPALHGDTAL
Mflv_4261|M.gilvum_PYR-GCK          ARFAHR----PSGIWAPECAYAPGMEIGYDDAGVTHFMVDGPSLRGDTSL
Mvan_2097|M.vanbaalenii_PYR-1       HRFAHS----PTGIWAPECAYSPGMEAGYADAGVSHFMVDGPSLHGDTAL
Mb3057|M.bovis_AF2122/97            LRLAHR----PKGIWAPECAYAPGMEVDYATAGVSHFMVDGPSLHGDTAL
Rv3031|M.tuberculosis_H37Rv         LRLAHR----PKGIWAPECAYAPGMEVDYATAGVSHFMVDGPSLHGDTAL
MLBr_01714|M.leprae_Br4923          LRLAHR----PTGIWAPECAYAPGMEHDYSAAGITHFMVDGPSLHGDTAL
MAV_3878|M.avium_104                LRLGARKGRGPGGIWAPECAYAPGLEHDYAAAGVTHFMVDGPSLHGDTAL
MMAR_1682|M.marinum_M               LRMAHS----PSGIWAPECAYAPGMEHDYAAAAVSHFMVDGPSLHGDTAL
MUL_1920|M.ulcerans_Agy99           LRMAHS----PSGIWAPECAYAPGMEHDYAAAAVSHFMVDGPSLHGDTAL
MAB_3365|M.abscessus_ATCC_1997      QRFGHA----PTGIWAPECAYAPGMEEGYAAAGVKHFMVDGPSLQGDTSL
                                     *:.      * *********:**:* .*  * : *******:*:***:*

MSMEG_2349|M.smegmatis_MC2_155      GRPVGESDVIAFGRDLQVSYRVWSPKSGYPGHGAYRDFHTYDHTTGLKPA
TH_2192|M.thermoresistible__bu      GRPVGDTDVIAFGRDLQVSYRVWSPKSGYPGHGAYRDFHTFDHVTGLKPV
Mflv_4261|M.gilvum_PYR-GCK          GRPVGGSDVVAFGRDLQVSYRVWSPKSGYPGHSAYRDFHTYDHATGLKPA
Mvan_2097|M.vanbaalenii_PYR-1       GRPVGDSGVVAFGRDLQVSYRVWSPKSGYPGHAAYRDFHTYDHATGLKPA
Mb3057|M.bovis_AF2122/97            GRPVGKTDVVAFGRDLQVSYRVWSPKSGYPGHAAYRDFHTYDHLTGLKPA
Rv3031|M.tuberculosis_H37Rv         GRPVGKTDVVAFGRDLQVSYRVWSPKSGYPGHAAYRDFHTYDHLTGLKPA
MLBr_01714|M.leprae_Br4923          GRPVGDTAVVAFGRDLQVSYRVWSPKSGYPGHAAYRDFHTYDHLTGLKPA
MAV_3878|M.avium_104                GRPVGDTDVVAFGRDLQVSYRVWSPKSGYPGHPAYRDFHTYDHLTGLKPA
MMAR_1682|M.marinum_M               GRPVGDTDVVAFGRDLQVSYRVWSPKSGYPGHAAYRDFHTYDHLTGLKPA
MUL_1920|M.ulcerans_Agy99           GRPVGDTDVVAFGRDLQVSYRVWSPKSGYPGHAAYRDFHTYDHLTGLKPA
MAB_3365|M.abscessus_ATCC_1997      GRTVGDSDVVAFGRDLAVSYRVWSPKSGYPGHAAYRDFHTYDHDTGLKPA
                                    **.** : *:****** *************** *******:** *****.

MSMEG_2349|M.smegmatis_MC2_155      RVTGRNVPSEQKAPYEPERADRAVDVHVADFVEVVRRRLLDESQRIGRPA
TH_2192|M.thermoresistible__bu      RVTGRTVPSEEKAPYDPQRADRAVDAHVADFVEVVRNRLIEESGRIGRPA
Mflv_4261|M.gilvum_PYR-GCK          RVTGRNVPSDAKAPYDPARADAAVDVHVADFVDTVRRRLASESERIGRPA
Mvan_2097|M.vanbaalenii_PYR-1       RVTGRAVPSEEKAPYDPARADAAVDVHVADFVETVRQRLSAESARIGRPA
Mb3057|M.bovis_AF2122/97            RVTGRNVPSEQKAPYDPERADRAVDVHVADFVDVVRNRLLSESERIGRPA
Rv3031|M.tuberculosis_H37Rv         RVTGRNVPSEQKAPYDPERADRAVDVHVADFVDVVRNRLLSESERIGRPA
MLBr_01714|M.leprae_Br4923          RVTGCNVPSEAKAPYDPDHADKVVDAHVDDFVGVVRNRLFTESERIGRPA
MAV_3878|M.avium_104                RVTGRNVPSEGKAPYDPDRADHAVDLHVADFVDVVRNRLTSESERIGRPA
MMAR_1682|M.marinum_M               RVTGRNVASEAKAPYDPQRADRAIDVHVADFVEVVRGRLIAESQRIGRPA
MUL_1920|M.ulcerans_Agy99           RVTGRNVASEAKAPYDPQRADRAIDVHVADFVEVVRGRLIAESQRIGRPA
MAB_3365|M.abscessus_ATCC_1997      RVTGRNVPSESKAPYDPERANAAIDIHVRDFVDTVRQRLVDESSRIGRPA
                                    ****  *.*: ****:* :*: .:* ** *** .** **  ** ******

MSMEG_2349|M.smegmatis_MC2_155      HVVAAFDTELFGHWWHEGPVWLERVLRALPQAGVRVGTLADAAADGFVGT
TH_2192|M.thermoresistible__bu      HVVAAFDTELFGHWWYEGPVWLERVLRALPAAGVRIGTLSDAIADGFIGT
Mflv_4261|M.gilvum_PYR-GCK          HVVAAFDTELFGHWWYEGPVWLERVLRALPAAGVRVGTLSDAIAEGYVGA
Mvan_2097|M.vanbaalenii_PYR-1       HVVAAFDTELFGHWWYEGPVWLERVLRALPAAGVRVGTLSDAIADGFVGS
Mb3057|M.bovis_AF2122/97            HVIAAFDTELFGHWWYEGPTWLQRVLRALPAAGVRVGTLSDAIADGFVGD
Rv3031|M.tuberculosis_H37Rv         HVIAAFDTELFGHWWYEGPTWLQRVLRALPAAGVRVGTLSDAIADGFVGD
MLBr_01714|M.leprae_Br4923          HVVAAFDTELFGHWWYEGPIWLQRVLRALPTAGVRVGTLSDALAGGFVGN
MAV_3878|M.avium_104                HVVAAFDTELFGHWWYEGPRWLARVLRALPEAGVRVGTLHDAIAGGFVGD
MMAR_1682|M.marinum_M               HVVAAFDTELFGHWWYEGPTWLQRVLRALPAAGVRVGTLHDAMANGFVGA
MUL_1920|M.ulcerans_Agy99           HVVAAFDTELFGHWWYEGPTWLQRVLRALPAAGVRVGTLHDAMANGFVGA
MAB_3365|M.abscessus_ATCC_1997      HVIAAFDTELYGHWWYEGPTWLERVLRALPEAGIQVGTLEQAREQGYVGE
                                    **:*******:****:*** ** ******* **:::*** :*   *::* 

MSMEG_2349|M.smegmatis_MC2_155      PVELPPSSWGSGKDWQVWSGQKVADLVQLNSEVVDNALATVDKALTQHAT
TH_2192|M.thermoresistible__bu      PVQLPASSWGSGKDWRVWSGPQVADLVELNAEVVEGALATVDKALAHNAA
Mflv_4261|M.gilvum_PYR-GCK          PVDLPPSSWGSGKDWQVWSGDQVADLVQLNSEVVDAALSTVDKALAHGAA
Mvan_2097|M.vanbaalenii_PYR-1       PVELPPSSWGSGKDWQVWSGEQVADLVQLNSEVVDTALSTVDKALARGGS
Mb3057|M.bovis_AF2122/97            PVELPPSSWGSGKDWQVWSGAKVADLVQLNSEVVDTALTTIDKALAQTAS
Rv3031|M.tuberculosis_H37Rv         PVELPPSSWGSGKDWQVWSGAKVADLVQLNSEVVDTALTTIDKALAQTAS
MLBr_01714|M.leprae_Br4923          TVTLPPSSWGSGKDWQVWAGDKVADLVQLNNEVVDTALTTVDKVLAQTTS
MAV_3878|M.avium_104                PVDLPPSSWGSGKDWQVWAGDQVADLVQLNSEVVDTALSTVDKALSQAGS
MMAR_1682|M.marinum_M               PVELPPSSWGSGKDWQVWNGPKVSDLVQLNSEVVDTALTTVDKALAQTAS
MUL_1920|M.ulcerans_Agy99           PVELPPSSWGSGKDWQVWNGPKVSDLVQLNSEVVDTALTTVDKALAQTAS
MAB_3365|M.abscessus_ATCC_1997      PFDLPASSWGSGKDWHVWNGEKVADLVQLNTEVVDTALTAVDKALNEQPA
                                    .. **.*********:** * :*:***:** ***: **:::**.* .  :

MSMEG_2349|M.smegmatis_MC2_155      ----VGSPVTRDRVADQILRETLLTVSSDWPFMVSKDSAAEYARYRAHLH
TH_2192|M.thermoresistible__bu      ----LGAPAPRDRVADQILRETLLTVSSDWPFMVSKDSAADYARYRAHLH
Mflv_4261|M.gilvum_PYR-GCK          ----LGSPTPRDFVADQILRETLLTVSSDWPFMVSKDSAADYARYRAHLH
Mvan_2097|M.vanbaalenii_PYR-1       ----LDAPTPRDFVADQILRETLLTVSSDWPFMVSKDSAADYARYRAHLH
Mb3057|M.bovis_AF2122/97            ----LDGPLPRDHVADQILRETLLTVSSDWPFMVSKDSAADYARYRAHLH
Rv3031|M.tuberculosis_H37Rv         ----LDGPLPRDHVADQILRETLLTVSSDWPFMVSKDSAADYARYRAHLH
MLBr_01714|M.leprae_Br4923          ----LDGLLPRNHVADQLLRETLLTVSSDWPFMVSKDSAADYARYRAHLH
MAV_3878|M.avium_104                QPAALDGPVPRDHVADQILRETLLTVSSDWPFMVSKDSAADYARYRAHLH
MMAR_1682|M.marinum_M               ----LDGPIPRDHVADQILRETLLTVSSDWPFMVSKDSAADYARYRAHLH
MUL_1920|M.ulcerans_Agy99           ----LDGPIPRDHVADQILRETLLTVSSDWPFMVSKDSAADYARYRAHLH
MAB_3365|M.abscessus_ATCC_1997      -------PHTRNRVADQILREALLTVSSDWPFMVSKDSAADYARYRAHLH
                                             .*: ****:***:******************:*********

MSMEG_2349|M.smegmatis_MC2_155      AHATREISDALAAGRREQAERLADGWNKADGLFGALDARRLPR-----
TH_2192|M.thermoresistible__bu      AHATREISDALAAGRREHALRLAEGWNRADGLFGALDARRLPAMKEIS
Mflv_4261|M.gilvum_PYR-GCK          AHATREISDALASGRREHAQQLADGWNRADGLFGALDARRLPAP----
Mvan_2097|M.vanbaalenii_PYR-1       AHATREISAALASGRDDHAQRLAEGWNRADGLFGALDARRLPGR----
Mb3057|M.bovis_AF2122/97            AHATREIAGALAAGRRDTARRLAEGWNRADGLFGALDARRLPK-----
Rv3031|M.tuberculosis_H37Rv         AHATREIAGALAAGRRDTARRLAEGWNRADGLFGALDARRLPK-----
MLBr_01714|M.leprae_Br4923          AHATREIAGALASGRRDTAAQLADGWNRADGLFGALDARRLPR-----
MAV_3878|M.avium_104                AHATREIAGALASGRRDTAQRLADGWNRADGLFGALDARRLPR-----
MMAR_1682|M.marinum_M               AHATREIAGALASGRRDNAQRLAQGWNRADGLFGALDARRLPK-----
MUL_1920|M.ulcerans_Agy99           AHATREIAGALASGRRDNAQRLAQGWNRADGLFGALDARRLPK-----
MAB_3365|M.abscessus_ATCC_1997      AHATREIAGALASGRHDVASRLADGWNRADGLFGALDARRLPR-----
                                    *******: ***:** : * :**:***:**************