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M. smegmatis MC2 155 MSMEG_1975 (-)

annotation: amidohydrolase 2
coordinates: 2057028 - 2058071
length: 347

MYEKDGQQYFIVDSHVHLWDGRASNLKNVHGKQFIDCFYDYHKNLSPEEALWDYDTYTYYGGDRLMKDLF
TDGYVDHAIFQATLLSDFYVTGFGQTEEAFALTQRHPGKLTYNHAYDPRYGEAGLEQLRRDADRMGLQGV
KLYTAEWHGDSRGYKLDEPWSRRYLEEAIKLGIKNVHVHKGPTIRPLDRDAFDVADIDKVATDYLELNFV
VEHVGLPRLEDFCWIATQESNVYGGLAVAIPFIHTRPRYFAQIIGELLYWIGEDKILFASDYALWTPKWL
IEKFVDFQIPEDMLGEYTQITTEQKRKVLGLNAASLYDIDVPAELRLPTPGQDTVEVAAGAKESVSI
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_1975--100% (347)amidohydrolase 2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3540c-8e-0526.14% (176) hypothetical protein Mb3540c
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv3510c-8e-0526.14% (176) hypothetical protein Rv3510c
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104MAV_0646-7e-0532.35% (102) amidohydrolase family protein
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb3540c|M.bovis_AF2122/97           -------------MTIDVWMQHPT--QRFLHGDMFASLRRWTGGSIPETD
Rv3510c|M.tuberculosis_H37Rv        -------------MTIDVWMQHPT--QRFLHGDMFASLRRWTGGSIPETD
MAV_0646|M.avium_104                -------------MTIDVWMQHPT--VRFLRSDMLASLRRWTGGSIPDTD
MSMEG_1975|M.smegmatis_MC2_155      MYEKDGQQYFIVDSHVHLWDGRASNLKNVHGKQFIDCFYDYHKNLSPEEA
                                                   :.:*  :.:   ..   ::: .:  :  .  *:  

Mb3540c|M.bovis_AF2122/97           IPIEATVSSMDAGGVTLGLLSA-------WRGPNGQDLISN-----DAVA
Rv3510c|M.tuberculosis_H37Rv        IPIEATVSSMDAGGVTLGLLSA-------WRGPNGQDLISN-----DAVA
MAV_0646|M.avium_104                IPIEATLASMDAAGVGYGLLSA-------WRGPNGQDLVSN-----DEVA
MSMEG_1975|M.smegmatis_MC2_155      LWDYDTYTYYGGDRLMKDLFTDGYVDHAIFQATLLSDFYVTGFGQTEEAF
                                    :    * :  ..  :  .*::        ::..  .*:  .     : . 

Mb3540c|M.bovis_AF2122/97           EWVRLYPNRFAGLAAVDLDRPMAAVRELRRRVGEG-FVGLRVVPWLWGAP
Rv3510c|M.tuberculosis_H37Rv        EWVRLYPNRFAGLAAVDLDRPMAAVRELRRRVGEG-FVGLRVVPWLWGAP
MAV_0646|M.avium_104                QWVAAHPNRFAGLAAVDLDRPMEAVRELRCRIADGGFVGLRVVPWLWNAP
MSMEG_1975|M.smegmatis_MC2_155      ALTQRHPGKLTYNHAYDPRYGEAGLEQLRRDADRMGLQGVKLYTAEWHGD
                                      .  :*.:::   * *      .:.:**       : *::: .  * . 

Mb3540c|M.bovis_AF2122/97           PTDRRYYPLFA-ECVQSAVPFCTQVGHTGP---LRPSE-TGRPIPYIDQV
Rv3510c|M.tuberculosis_H37Rv        PTDRRYYPLFA-ECVQSAVPFCTQVGHTGP---LRPSE-TGRPIPYIDQV
MAV_0646|M.avium_104                PTDRRYYPLFA-ACVEAGVPFCTQVGHTGP---LRPSE-TGRPIPYIDQV
MSMEG_1975|M.smegmatis_MC2_155      SRGYKLDEPWSRRYLEEAIKLGIKNVHVHKGPTIRPLDRDAFDVADIDKV
                                    . . :    ::   :: .: :  :  *.     :** :  .  :. **:*

Mb3540c|M.bovis_AF2122/97           ALDFPELVIVCGHVGYPWTEEMVAVARKHENVY--IDTSAYTIKRLP---
Rv3510c|M.tuberculosis_H37Rv        ALDFPELVIVCGHVGYPWTEEMVAVARKHENVY--IDTSAYTIKRLP---
MAV_0646|M.avium_104                ALDFPELVIVCGHVGYPWTEEMVAVARKHENVY--IDTSAYTIERLP---
MSMEG_1975|M.smegmatis_MC2_155      ATDYLELNFVVEHVGLPRLEDFCWIATQESNVYGGLAVAIPFIHTRPRYF
                                    * *: ** :*  *** *  *::  :* :..***  : .:   *.  *   

Mb3540c|M.bovis_AF2122/97           GKLVRFMKTDTGQRKVLFGTNYPMIAHTHALTGLDELGLSD---------
Rv3510c|M.tuberculosis_H37Rv        GKLVRFMKTDTGQRKVLFGTNYPMIAHTHALTGLDELGLSD---------
MAV_0646|M.avium_104                DELVRFIKTGTGQRKVLFGTNYPMITAEHALAGLDGLGLSD---------
MSMEG_1975|M.smegmatis_MC2_155      AQIIGELLYWIGEDKILFASDYALWTPKWLIEKFVDFQIPEDMLGEYTQI
                                     :::  :    *: *:**.::*.: :    :  :  : :.:         

Mb3540c|M.bovis_AF2122/97           --EARRDFLHGNAVRVFKLDPRGKVQT--------------------
Rv3510c|M.tuberculosis_H37Rv        --EARRDFLHGNAVRVFKLDPRGKVQT--------------------
MAV_0646|M.avium_104                --EARRDFLHGNAERVFRLEAAT------------------------
MSMEG_1975|M.smegmatis_MC2_155      TTEQKRKVLGLNAASLYDIDVPAELRLPTPGQDTVEVAAGAKESVSI
                                      * :*..*  **  :: ::