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VLSKLLRLGEGRMVKRLRKVADYVNALSDDVEKLSDAELRAKTEEFKKRVADGEDLDDLLPEAFAVAREA AWRVLNQRHFDVQVMGGAALHFGNVAEMKTGEGKTLTAVLPSYLNALSGKGVHVVTVNDYLARRDSEWMG RVHRFLGLDVGVILSGMTPDERRAAYAADITYGTNNEFGFDYLRDNMAHSVDDMVQRGHNFAIVDEVDSI LIDEARTPLIISGPADGASHWYQEFARIVPMMEKDVHYEVDLRKRTVGVHELGVEFVEDQLGIDNLYEAA NSPLVSYLNNALKAKELFQRDKDYIVRNGEVLIVDEFTGRVLMGRRYNEGMHQAIEAKERVEIKAENQTL ATITLQNYFRLYDKLSGMTGTAETEAAELHEIYKLGVVPIPTNKPMVRQDQSDLIYKTEEAKFLAVVDDV AERHAKGQPVLIGTTSVERSEYLSKMLTKRRVPHNVLNAKYHEQEANIIAEAGRRGAVTVATNMAGRGTD IVLGGNVDFLADKRLRERGLDPVETPEEYEAAWHEVLPQVKAECAKEAEQVIEAGGLYVLGTERHESRRI DNQLRGRSGRQGDPGESRFYLSLGDELMRRFNGATLETLLTRLNLPDDVPIEAKMVSRAIKSAQTQVEQQ NFEVRKNVLKYDEVMNQQRKVIYAERRRILEGENLAEQAHKMLVDVITAYVDGATAEGYAEDWDLETLWT ALKTLYPVGIDHRDLIDSDAVGEPGELTREELLDALIKDAERAYAEREKQIEAIAGEGAMRQLERNVLLN VIDRKWREHLYEMDYLKEGIGLRAMAQRDPLVEYQREGYDMFVGMLEALKEESVGFLFNVQVEAAPQQPQ VAPQAPPPTLSEFAAAAAAKASDSAAKPDSGSVATKERAEAERPAPALRAKGIDNEAPPLTYTGPSEDGT AQVQRSGNGGRHAAPAGGSRRERREAARKQAKADRPAKSHRKG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_1881 | secA | - | 100% (953) | preprotein translocase subunit SecA |
M. smegmatis MC2 155 | MSMEG_3654 | - | e-121 | 40.33% (667) | preprotein translocase subunit SecA |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3268c | secA1 | 0.0 | 83.21% (959) | preprotein translocase subunit SecA |
M. gilvum PYR-GCK | Mflv_4705 | - | 0.0 | 79.98% (949) | preprotein translocase subunit SecA |
M. tuberculosis H37Rv | Rv3240c | secA1 | 0.0 | 83.21% (959) | preprotein translocase subunit SecA |
M. leprae Br4923 | MLBr_00779 | secA | 0.0 | 78.29% (958) | preprotein translocase subunit SecA |
M. abscessus ATCC 19977 | MAB_3580c | - | 0.0 | 78.59% (953) | preprotein translocase subunit SecA |
M. marinum M | MMAR_1305 | secA1 | 0.0 | 82.01% (956) | preprotein translocase SecA1 1 subunit |
M. avium 104 | MAV_2894 | - | 1e-118 | 39.51% (653) | preprotein translocase subunit SecA |
M. thermoresistible (build 8) | TH_0994 | secA | 0.0 | 90.58% (807) | PROBABLE PREPROTEIN TRANSLOCASE SECA1 1 SUBUNIT |
M. ulcerans Agy99 | MUL_2576 | secA1 | 0.0 | 81.28% (956) | preprotein translocase subunit SecA |
M. vanbaalenii PYR-1 | Mvan_1762 | - | 0.0 | 80.51% (949) | preprotein translocase subunit SecA |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_4705|M.gilvum_PYR-GCK MLSKLLRIGEGRMVKRLKGVSDYVN--TLSDDMEKLS-----DADLRAKT Mvan_1762|M.vanbaalenii_PYR-1 MLSKLLRLGEGRMVKRLKGVADYVN--TLSDDIEKLS-----DAELRGKT MSMEG_1881|M.smegmatis_MC2_155 MLSKLLRLGEGRMVKRLRKVADYVN--ALSDDVEKLS-----DAELRAKT Mb3268c|M.bovis_AF2122/97 MLSKLLRLGEGRMVKRLKKVADYVG--TLSDDVEKLT-----DAELRAKT Rv3240c|M.tuberculosis_H37Rv MLSKLLRLGEGRMVKRLKKVADYVG--TLSDDVEKLT-----DAELRAKT MLBr_00779|M.leprae_Br4923 MLSKLLRLGEGRIVKRLKRVAEYVN--TLSDNVEKLT-----DVELKAKT MMAR_1305|M.marinum_M MLSKLLRVGEGRMVKRLKKVADYVE--SLSGDVEKLT-----DAELRAKT MUL_2576|M.ulcerans_Agy99 MLSKLLRVGEGRMVKRLKKVADYVE--SLSGDVEKLT-----DAELRAKT MAB_3580c|M.abscessus_ATCC_199 MLSKLLRLGEGRMVKRLKGVADYVN--TLSDDIEKLS-----DAELQAKT TH_0994|M.thermoresistible__bu VLSKLLRLGEGRMVKRLRKVADYVN--TLSDDVEKLS-----DAELRAKT MAV_2894|M.avium_104 -MPKTNRAQPGRLSSRFWRLLGASTEKNRSRSLTLVTDSSEYDDEAAGLT :.* * **: .*: : * .: :: * : . * Mflv_4705|M.gilvum_PYR-GCK DEFRRRLADGK--EDLDDL--MPEAFAVAREAAWRVLNQKHFDVQVMGGA Mvan_1762|M.vanbaalenii_PYR-1 DEFRARLAGGK--EDLDDV--MPEAFAVVREAAWRVLNQRHFDVQIMGGA MSMEG_1881|M.smegmatis_MC2_155 EEFKKRVADG---EDLDDL--LPEAFAVAREAAWRVLNQRHFDVQVMGGA Mb3268c|M.bovis_AF2122/97 DEFKRRLADQKNPETLDDL--LPEAFAVAREAAWRVLDQRPFDVQVMGAA Rv3240c|M.tuberculosis_H37Rv DEFKRRLADQKNPETLDDL--LPEAFAVAREAAWRVLDQRPFDVQVMGAA MLBr_00779|M.leprae_Br4923 DEFKQRLADEKNPESLDDL--LPEAFAVAREAAWRVLDQRPFDVQVMGGA MMAR_1305|M.marinum_M DEFKKRHAEG---ESLDEL--LPEAFAVAREAAWRVLDQRPFEVQLMGAA MUL_2576|M.ulcerans_Agy99 DEFKKRHAEG---ESLDEL--LPEAFAVAREAAWRVLGQRPFEVQLMGAA MAB_3580c|M.abscessus_ATCC_199 GEFKGRLEKG---ETLDDL--MPEAFAVAREASWRVLSQRHFDVQVMGGA TH_0994|M.thermoresistible__bu DEFKKRVAAG---EDLDDL--LPEAFAVAREAAWRVLSQRHFDVQVMGGA MAV_2894|M.avium_104 DEQLRKAAGLLNLEDLAESEDIPQFLAIAREAAERATGLRPFDVQLLGAL * : * * : :*: :*:.***: *. . : *:**::*. Mflv_4705|M.gilvum_PYR-GCK ALHFGNVAEMKTGEGKTLTSVLPAYLNALTGKGVHIVTVNEYLAKRDAEQ Mvan_1762|M.vanbaalenii_PYR-1 ALHFGNVAEMKTGEGKTLTSVLPAYLNALPGKGVHIVTVNEYLAKRDAEQ MSMEG_1881|M.smegmatis_MC2_155 ALHFGNVAEMKTGEGKTLTAVLPSYLNALSGKGVHVVTVNDYLARRDSEW Mb3268c|M.bovis_AF2122/97 ALHLGNVAEMKTGEGKTLTCVLPAYLNALAGNGVHIVTVNDYLAKRDSEW Rv3240c|M.tuberculosis_H37Rv ALHLGNVAEMKTGEGKTLTCVLPAYLNALAGNGVHIVTVNDYLAKRDSEW MLBr_00779|M.leprae_Br4923 ALHLGNVAEMKTGEGKTLTCVLPAYLNALAGKGVHIVTVNDYLAKRDSEW MMAR_1305|M.marinum_M ALHLGNVAEMKTGEGKTLTSVLPAYLNGIGGKGVHIVTVNDYLAKRDSEW MUL_2576|M.ulcerans_Agy99 ALHLGNVAEMKTGEGKTLTSVLPAYLNGIGGKGVHIVTVNDYLAKRDSEW MAB_3580c|M.abscessus_ATCC_199 ALHAGNIAEMKTGEGKTLTCVLPAYLNALAGKGTHVVTVNDYLAKRDSEW TH_0994|M.thermoresistible__bu ALHFGNVAEMKTGEGKTLTAVLPAYLNALTGKGVHIVTVNDYLAKRDSEW MAV_2894|M.avium_104 RMLAGDVIEMATGEGKTLAGAIAAAGYALAGRHVHVVTINDYLARRDAEW : *:: ** *******: .:.: .: *. .*:**:*:***:**:* Mflv_4705|M.gilvum_PYR-GCK MGRVHRFLGLDVDVILGTLTPDQRRAAYNADITYGTNWELGFDYLRDNMA Mvan_1762|M.vanbaalenii_PYR-1 MGRVHRFLGLDVDVILGTLTPDQRRAAYNADITYGTNWELGFDYLRDNMA MSMEG_1881|M.smegmatis_MC2_155 MGRVHRFLGLDVGVILSGMTPDERRAAYAADITYGTNNEFGFDYLRDNMA Mb3268c|M.bovis_AF2122/97 MGRVHRFLGLQVGVILATMTPDERRVAYNADITYGTNNEFGFDYLRDNMA Rv3240c|M.tuberculosis_H37Rv MGRVHRFLGLQVGVILATMTPDERRVAYNADITYGTNNEFGFDYLRDNMA MLBr_00779|M.leprae_Br4923 MGRVHRFLGLQVGVILASMTPDERRVAYNADITYGTNNEFGFDYLRDNMA MMAR_1305|M.marinum_M MGRVHRFLGLDVGVILAQMTPEERRVAYNADITYGTNNEFGFDYLRDNMA MUL_2576|M.ulcerans_Agy99 MGRVHRFLGLDVGVILAQMTPEERRVAYNADITYGTNNEFGFDYLRDNMA MAB_3580c|M.abscessus_ATCC_199 MGRVHRFLGLDVGVILSQMTPLERRDAYNADITYGTNNEFGFDYLRDNMT TH_0994|M.thermoresistible__bu MGRVHRFLGLEVGVILSGMTPDQRRAAYNADITYGTNNEFGFDYLRDNMA MAV_2894|M.avium_104 MGPLIEAMGLTVGWITAESSSEERRAAYGCDVTYASVNEIGFDVLRDQLV ** : . :** *. * . :. :** ** .*:**.: *:*** ***::. Mflv_4705|M.gilvum_PYR-GCK LRLEDCVQRGHNFAIVDEVDSILIDEARTPLIISGPAD-GGSNWYTEFAR Mvan_1762|M.vanbaalenii_PYR-1 LRLEDCVQRGHHFAIVDEVDSILIDEARTPLIISGPAD-GGSNWYTEFAR MSMEG_1881|M.smegmatis_MC2_155 HSVDDMVQRGHNFAIVDEVDSILIDEARTPLIISGPAD-GASHWYQEFAR Mb3268c|M.bovis_AF2122/97 HSLDDLVQRGHHYAIVDEVDSILIDEARTPLIISGPAD-GASNWYTEFAR Rv3240c|M.tuberculosis_H37Rv HSLDDLVQRGHHYAIVDEVDSILIDEARTPLIISGPAD-GASNWYTEFAR MLBr_00779|M.leprae_Br4923 HSLDDLVQRGHSYAIVDEVDSILIDEARTPLIISGSAD-GASNWYTEFAR MMAR_1305|M.marinum_M HTLDDCVQRGHNFAIVDEVDSILIDEARTPLIISGPAD-GSSNWYTEFAR MUL_2576|M.ulcerans_Agy99 HTLDDCVQRGHNFVIVDEVDSILIDEARTPLIISGPAD-GSSNWYTEFAR MAB_3580c|M.abscessus_ATCC_199 HSLDELVQRGHAFAIVDEVDSILIDEARTPLIISGPAD-GASNWYTEFAR TH_0994|M.thermoresistible__bu HSLADLVQRGHHYAIVDEVDSILIDEARTPLIISGPADSGATNWYVEFAR MAV_2894|M.avium_104 TDVADLVSPNPDVALIDEADSVLVDEALVPLVLAGTTH--RETPRLEIIK : : *. . .::**.**:*:*** .**:::*.:. *: : Mflv_4705|M.gilvum_PYR-GCK LAPLMEKDVHYEVDIKKRVVGINEIGVEFVEDQLG-IENLYEAANSPLIS Mvan_1762|M.vanbaalenii_PYR-1 LAPLMKPDVHYEVDIKKRVVGINEAGVEFVEDQLG-IENLYEAANSPLIS MSMEG_1881|M.smegmatis_MC2_155 IVPMMEKDVHYEVDLRKRTVGVHELGVEFVEDQLG-IDNLYEAANSPLVS Mb3268c|M.bovis_AF2122/97 LAPLMEKDVHYEVDLRKRTVGVHEKGVEFVEDQLG-IDNLYEAANSPLVS Rv3240c|M.tuberculosis_H37Rv LAPLMEKDVHYEVDLRKRTVGVHEKGVEFVEDQLG-IDNLYEAANSPLVS MLBr_00779|M.leprae_Br4923 LVRLMDKDVHYEVDLRKRTVGVHEKGMEFVEDQLG-IDNLYEVANSPLVS MMAR_1305|M.marinum_M LAPLMEKDTHYEVDLRKRTVGVHELGVEFVEDQLG-IDNLYEAANSPLVS MUL_2576|M.ulcerans_Agy99 LAPLMEKDTHYEVDLRKRTVGVHELGVEFVEDQLG-IDNLYEAANSPLVS MAB_3580c|M.abscessus_ATCC_199 IVPLMEKDTHYEVDIRKRTIGVHELGVEFVEDQLG-IDNLYEAANSPLVS TH_0994|M.thermoresistible__bu IAPLMQKDVHYEVDLRKRTVGVHELGVEFVEDQLG-IDNLYEAANSPLVS MAV_2894|M.avium_104 LVGELEAGTDYDTDADSRNVHLTDVGARKVEKALGGIDLYSEEHVGTTLT :. :. ...*:.* .* : : : * . **. ** *: * .. :: Mflv_4705|M.gilvum_PYR-GCK YLNNAIKAKELFERDKHYIVRNGEVFIVDEFTGRMLVGRRYNEGLHQAIE Mvan_1762|M.vanbaalenii_PYR-1 YLNNAIKAKELFERDKHYIVRNGEVFIVDEFTGRMLVGRRYNEGLHQAIE MSMEG_1881|M.smegmatis_MC2_155 YLNNALKAKELFQRDKDYIVRNGEVLIVDEFTGRVLMGRRYNEGMHQAIE Mb3268c|M.bovis_AF2122/97 YLNNALKAKELFSRDKDYIVRDGEVLIVDEFTGRVLIGRRYNEGMHQAIE Rv3240c|M.tuberculosis_H37Rv YLNNALKAKELFSRDKDYIVRDGEVLIVDEFTGRVLIGRRYNEGMHQAIE MLBr_00779|M.leprae_Br4923 YLNNALKAKELFNRDKDYIVRDGEVLIVDEFTGRVLIGRRYNEGMHQAIE MMAR_1305|M.marinum_M YLNNALKAKELFNRDKDYIVRNGEVLIVDEFTGRVLIGRRYNEGMHQAIE MUL_2576|M.ulcerans_Agy99 YLNNALKAKELFNRDKDYIVRNGEVLIVDEFTGRVLIGRRYSEGMHQAIE MAB_3580c|M.abscessus_ATCC_199 YLNNAIKAKELFTRDKDYIVREGEVLIVDEFTGRVLMGRRYNEGMHQAIE TH_0994|M.thermoresistible__bu YLNNALKAKELFHRDKDYIVRNGEVLIVDEFTGRVLVGRRYNEGMHQAIE MAV_2894|M.avium_104 EVNVALHAHVLLQRDVHYIVRDDAVHLINASRGRIAQLQRWPDGLQAAVE :* *::*: *: ** .****:. * ::: **: :*: :*:: *:* Mflv_4705|M.gilvum_PYR-GCK AKEHVEIKAENQTVAQITLQNYFRMYNKLAGMTGTAETEAAELHEIYKLG Mvan_1762|M.vanbaalenii_PYR-1 AKEHVEIKAENQTVAQVTLQNYFRMYEKLAGMTGTAETEAAELHEIYKLG MSMEG_1881|M.smegmatis_MC2_155 AKERVEIKAENQTLATITLQNYFRLYDKLSGMTGTAETEAAELHEIYKLG Mb3268c|M.bovis_AF2122/97 AKEHVEIKAENQTLATITLQNYFRLYDKLAGMTGTAQTEAAELHEIYKLG Rv3240c|M.tuberculosis_H37Rv AKEHVEIKAENQTLATITLQNYFRLYDKLAGMTGTAQTEAAELHEIYKLG MLBr_00779|M.leprae_Br4923 AKEHVEIKAENQTLATITLQNYFRLYDKLAGMTGTAQTEAAELHEIYKLG MMAR_1305|M.marinum_M AKEHVEIKAENQTLATITLQNYFRLYNKLAGMTGTAQTEAAELHEIYKLG MUL_2576|M.ulcerans_Agy99 AKEHVEIKAENQTLATITLQNYFRLYNKHAGMTGTAQTEAAELHEIYKLG MAB_3580c|M.abscessus_ATCC_199 AKERVEIKAENQTLATITLQNYFRLYDKLAGMTGTAQTEAAELNEIYKLG TH_0994|M.thermoresistible__bu AKEGVEIKAENQTLATITLQNYFRLYDKLAGMTGTAETEAAELHEIYKLG MAV_2894|M.avium_104 AKEGIETTETGEVLDTITVQALINRYATVCGMTGTALAAGEQLRQFYKLG *** :* . .:.: :*:* :. * . .****** : . :*.::**** Mflv_4705|M.gilvum_PYR-GCK VVPIPTNRPMIRADQSDLIYKTEEAKYIAVVDDVVERYEKGQPVLIGTTS Mvan_1762|M.vanbaalenii_PYR-1 VVPIPTNRPMVRKDQSDLIYKTEEAKYIAVVDDVAERYEKGQPVLIGTTS MSMEG_1881|M.smegmatis_MC2_155 VVPIPTNKPMVRQDQSDLIYKTEEAKFLAVVDDVAERHAKGQPVLIGTTS Mb3268c|M.bovis_AF2122/97 VVSIPTNMPMIREDQSDLIYKTEEAKYIAVVDDVAERYAKGQPVLIGTTS Rv3240c|M.tuberculosis_H37Rv VVSIPTNMPMIREDQSDLIYKTEEAKYIAVVDDVAERYAKGQPVLIGTTS MLBr_00779|M.leprae_Br4923 VVAIPTNKPMIREDRSDLIYKTEEAKYMAVVDDVAERYEKGQPVLIGTTS MMAR_1305|M.marinum_M VVPIPTNRPMVREDQSDLIYKTEEAKYIAVVDDVAERYEKGQPVLIGTTS MUL_2576|M.ulcerans_Agy99 VVPIPTNRPMVREDQSDLIYKTEEAKYIAVVDDVAERYEKGQPVLIGTTS MAB_3580c|M.abscessus_ATCC_199 VVSIPTNRPMVRKDQSDLIYKTEEAKYIAVVDDVVERYEKGQPVLIGTTS TH_0994|M.thermoresistible__bu VVPIPTNKPMIREDRADLIYKTEEAKFLAVADDIAERYQKGQPVLVGTTS MAV_2894|M.avium_104 VSPIPPNKPNIREDEADRVYITAAAKNDAIVEHIIEVHETGQPVLVGTRD * .**.* * :* *.:* :* * ** *:.:.: * : .*****:** . Mflv_4705|M.gilvum_PYR-GCK VERSEFLSRQFEKRRIPHNVLNAKFHEQEAGIIAEAGRLGAITVATNMAG Mvan_1762|M.vanbaalenii_PYR-1 VERSEFLSRQFEKRRIPHNVLNAKYHEQEAGIVAEAGRLGAITVATNMAG MSMEG_1881|M.smegmatis_MC2_155 VERSEYLSKMLTKRRVPHNVLNAKYHEQEANIIAEAGRRGAVTVATNMAG Mb3268c|M.bovis_AF2122/97 VERSEYLSRQFTKRRIPHNVLNAKYHEQEATIIAVAGRRGGVTVATNMAG Rv3240c|M.tuberculosis_H37Rv VERSEYLSRQFTKRRIPHNVLNAKYHEQEATIIAVAGRRGGVTVATNMAG MLBr_00779|M.leprae_Br4923 VERSEYLSRQFTKRHIPHNVLNAKYHEQEAGIVAVAGRRGGVTVATNMAG MMAR_1305|M.marinum_M VERSEYLSRQFTKRRIPHNVLNAKYHEQEAGIIAEAGRRGAITVATNMAG MUL_2576|M.ulcerans_Agy99 VERSEYLSRQFTKRRIPHNVLNAKYHEQEAGIIAEAGRRGAITVATNMAG MAB_3580c|M.abscessus_ATCC_199 VERSEYLSRQFTKRRVPHNVLNAKYHEQEAAIIAEAGRRGAITVATNMAG TH_0994|M.thermoresistible__bu VERSEYLSRLLTKRRIPHNVLNAKYHEQEAAIIAEAGRRGAVTVATNMAG MAV_2894|M.avium_104 VAESEELHERLLRRGVPAVVLNAKNDAEEAQVIAEAGKFGVVTVSTQMAG * .** * . : :* :* ***** . :** ::* **: * :**:*:*** Mflv_4705|M.gilvum_PYR-GCK RGTDIVLGGNVDYLLDRRLRQRGLDPIETPDEYEKGWHEELPHIKEQVAE Mvan_1762|M.vanbaalenii_PYR-1 RGTDIVLGGNVDYLLDRRLRQRGLDPIETPEEYEQGWHEELPHIKAEVAA MSMEG_1881|M.smegmatis_MC2_155 RGTDIVLGGNVDFLADKRLRERGLDPVETPEEYEAAWHEVLPQVKAECAK Mb3268c|M.bovis_AF2122/97 RGTDIVLGGNVDFLTDQRLRERGLDPVETPEEYEAAWHSELPIVKEEASK Rv3240c|M.tuberculosis_H37Rv RGTDIVLGGNVDFLTDQRLRERGLDPVETPEEYEAAWHSELPIVKEEASK MLBr_00779|M.leprae_Br4923 RGTDIVLGGNVDFLTDQRLRRRGLDPVETPDEYEQAWHSELPKVKEEAGQ MMAR_1305|M.marinum_M RGTDIVLGGNVDFLTDKRLRDNGLDPVETPDEYEQAWHQELPKVKEEAGD MUL_2576|M.ulcerans_Agy99 RGTDIVLGGNVDFLTDKRLRDNGLDPVETPDEYEQAWHQELPKVKEEAGD MAB_3580c|M.abscessus_ATCC_199 RGTDIVLGGNPDFLADKHLREQGLDPVETPDEYQAAWDETLQKFKDAAET TH_0994|M.thermoresistible__bu RGTDIVLGGNPDFLTDKRLREQGLDPVETPEEYEAAWHELLPKVKAECAR MAV_2894|M.avium_104 RGTDIRLGGSDEADHDR--------------------------------- ***** ***. : *: Mflv_4705|M.gilvum_PYR-GCK EAKDVIAAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLADE Mvan_1762|M.vanbaalenii_PYR-1 EAKDVIAAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLADE MSMEG_1881|M.smegmatis_MC2_155 EAEQVIEAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLGDE Mb3268c|M.bovis_AF2122/97 EAKEVIEAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLGDE Rv3240c|M.tuberculosis_H37Rv EAKEVIEAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLGDE MLBr_00779|M.leprae_Br4923 EAAEVIEAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLGDE MMAR_1305|M.marinum_M EATEVIEAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLGDE MUL_2576|M.ulcerans_Agy99 EATEVIKAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLGDE MAB_3580c|M.abscessus_ATCC_199 EAKEVQEAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLQDE TH_0994|M.thermoresistible__bu EAQEVIEAGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLGDE MAV_2894|M.avium_104 ----VAELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDD * ***:*:** **.:.*:*******:*******.* *: * *: Mflv_4705|M.gilvum_PYR-GCK LMRRFNGATLETLLTRLNLPDDVPIEAKMVSRAIKSAQTQVEQQNFDIRK Mvan_1762|M.vanbaalenii_PYR-1 LMRRFNGATLETLLTRLNLPDDVPIEAKMVSRAIKSAQTQVEQQNFDIRK MSMEG_1881|M.smegmatis_MC2_155 LMRRFNGATLETLLTRLNLPDDVPIEAKMVSRAIKSAQTQVEQQNFEVRK Mb3268c|M.bovis_AF2122/97 LMRRFNGAALETLLTRLNLPDDVPIEAKMVTRAIKSAQTQVEQQNFEVRK Rv3240c|M.tuberculosis_H37Rv LMRRFNGAALETLLTRLNLPDDVPIEAKMVTRAIKSAQTQVEQQNFEVRK MLBr_00779|M.leprae_Br4923 LMRRFHGATLEALLTRLNLPDDVPIEAKMVTRAIKSAQTQVEQQNFEVRK MMAR_1305|M.marinum_M LMRRFNGAALESLLTRLNLPDDVPIEAKMVTRAIKSAQTQVEQQNFEVRK MUL_2576|M.ulcerans_Agy99 LMRRFNGAALESLLTRLNLPDDVPIEAKMVTRAIKSAQTQVEQQNFEVRK MAB_3580c|M.abscessus_ATCC_199 LMRRFNGAALETILTRMNVPDDVPIEAKMVTNAIKSAQTQVEQQNFEVRK TH_0994|M.thermoresistible__bu LMRRFNGATLEALLTRLNLPDDVPIEAKMVTRAIKSAQTQVEQQNFEVRK MAV_2894|M.avium_104 VVAANLDRNKLPMETDPETGDGRIVSPKAAG-LLDHAQRVAEGRMLDVHA :: . .: * : *. :..* . :. ** .* : :::: Mflv_4705|M.gilvum_PYR-GCK EVLKYDEVMNQQRKVIYAERRRILEGENLRDQAEQMLVDVVTAYVDGATS Mvan_1762|M.vanbaalenii_PYR-1 EVLKYDEVMNQQRKVVYAERRRILEGENLAGQAHQILVDVITAYVDGATA MSMEG_1881|M.smegmatis_MC2_155 NVLKYDEVMNQQRKVIYAERRRILEGENLAEQAHKMLVDVITAYVDGATA Mb3268c|M.bovis_AF2122/97 NVLKYDEVMNQQRKVIYAERRRILEGENLKDQALDMVRDVITAYVDGATG Rv3240c|M.tuberculosis_H37Rv NVLKYDEVMNQQRKVIYAERRRILEGENLKDQALDMVRDVITAYVDGATG MLBr_00779|M.leprae_Br4923 NVLKYDEVMNQQRKVIYAERRRILEGESLQQQALGMVRDVITAYIDGATT MMAR_1305|M.marinum_M NVLKYDEVMNQQRKVIYAERRRILEGENLQQQAKDMLTDVITAYVDGATV MUL_2576|M.ulcerans_Agy99 NVLKYDEVMNQQRKVIYAERRRILEGENLQQQVKDMLTDVITAYVDGATV MAB_3580c|M.abscessus_ATCC_199 NVLKYDEVMNQQRKVIYAERRRILDGEDLQPQIQEMITDTIAAYVDGATA TH_0994|M.thermoresistible__bu NVLKYDEVMNQQRKVIYAERRRILEGENLREQALDMVRDVITAYVDGATA MAV_2894|M.avium_104 NTWRYNQLIAQQRAIIVDRRNTLLR---------------------TATA :. :*:::: *** :: .*. :* ** Mflv_4705|M.gilvum_PYR-GCK EGYSEDWDLEKLWEGLRQLYPVGIDHRDLIDSDAIGEPGELTRAELLEAL Mvan_1762|M.vanbaalenii_PYR-1 EGYSEDWDLEKLWEGLRQLYPVGIDHHDLIDSDAVGEPGELTREELLQAL MSMEG_1881|M.smegmatis_MC2_155 EGYAEDWDLETLWTALKTLYPVGIDHRDLIDSDAVGEPGELTREELLDAL Mb3268c|M.bovis_AF2122/97 EGYAEDWDLDALWTALKTLYPVGITADSLTRKDHEFERDDLTREELLEAL Rv3240c|M.tuberculosis_H37Rv EGYAEDWDLDALWTALKTLYPVGITADSLTRKDHEFERDDLTREELLEAL MLBr_00779|M.leprae_Br4923 DSYVEDWDLDALWSALGTLYPVGIKHESLTHADEDSECDELSRDELLEAL MMAR_1305|M.marinum_M EGYAEDWDLDALWTALKTLYPVGIKADTLMRRDQDSDRDDLTRDELLEAL MUL_2576|M.ulcerans_Agy99 EGYAEDWDLDALWTALKTLYPVGIKTDTLMRRDQDSDRDDLTRDELLQAL MAB_3580c|M.abscessus_ATCC_199 DGYHEDWDFDALWTALKTLYPVSLKPEELIASGEYGEADELSPEDLKAAL TH_0994|M.thermoresistible__bu EGYAEDWDLEQLWTALRQLYPISIDHHDLIDSDAVGEPGDLTRDELLQVL MAV_2894|M.avium_104 R----------------------------------------------EEL * Mflv_4705|M.gilvum_PYR-GCK VNDAKSAYSVREAEIEQIAGEGAMRQLERNVLLNVLDRKWREHLYEMDYL Mvan_1762|M.vanbaalenii_PYR-1 IADAERAYAAREAEIEEIAGEGAMRQLERNVLLNVLDRKWREHLYEMDYL MSMEG_1881|M.smegmatis_MC2_155 IKDAERAYAEREKQIEAIAGEGAMRQLERNVLLNVIDRKWREHLYEMDYL Mb3268c|M.bovis_AF2122/97 LKDAERAYAAREAELEEIAGEGAMRQLERNVLLNVIDRKWREHLYEMDYL Rv3240c|M.tuberculosis_H37Rv LKDAERAYAAREAELEEIAGEGAMRQLERNVLLNVIDRKWREHLYEMDYL MLBr_00779|M.leprae_Br4923 LIDAQHAYAAREAELAELAGEGAMRQLERNVLLNVVDRKWREHLYEMDYL MMAR_1305|M.marinum_M LQDADQAYAAREAELEELAGEGAMRQLERNVLLNVIDRKWREHLYEMDYL MUL_2576|M.ulcerans_Agy99 LQDADQAYAAREAELEELAGEGAMRQLERNVLLNVIDRKWREHLYEMDYL MAB_3580c|M.abscessus_ATCC_199 LEDAKKAYKAREAEIDGLAGEGSMRQLERNILLSVIDRKWREHLYEMDYL TH_0994|M.thermoresistible__bu LEDAERAYAKREAEIDELAGEGAMRQLERNVLLNVIDRKWREHLYEMDYL MAV_2894|M.avium_104 AELAPKRYR----ELAEEIPEERLETICRHIMLYHLDRGWADHLAYLADI * * :: * :. : *:::* :** * :** : : Mflv_4705|M.gilvum_PYR-GCK REGIGLRGLAQQRPEVEYARE--GYDMFIGMLDGMKEESVGFLFNVQVEP Mvan_1762|M.vanbaalenii_PYR-1 REGIGLRGLAQQRPEVEYARE--GYDMFIAMLDGMKEESVGFLFNVQVER MSMEG_1881|M.smegmatis_MC2_155 KEGIGLRAMAQRDPLVEYQRE--GYDMFVGMLEALKEESVGFLFNVQVEA Mb3268c|M.bovis_AF2122/97 KEGIGLRAMAQRDPLVEYQRE--GYDMFMAMLDGMKEESVGFLFNVTVEA Rv3240c|M.tuberculosis_H37Rv KEGIGLRAMAQRDPLVEYQRE--GYDMFMAMLDGMKEESVGFLFNVTVEA MLBr_00779|M.leprae_Br4923 KEGIGLRAMAQRDPLVEYQRE--GYDMFMAMLDGVKEESVGFLFNLAVEA MMAR_1305|M.marinum_M KEGIGLRAMAQRDPLVEYQRE--GYDMFMAMLDGMKEESVGFLFNVSVEA MUL_2576|M.ulcerans_Agy99 KEGIGLRAMAQRDPLVEYQRE--GYDMFMAMLDGVKEESVGFLFNVSVEA MAB_3580c|M.abscessus_ATCC_199 KEGIGLRAMAQRDPLVEYQRE--GYDMFTAMLDGLKEESVGFLFNINVEV TH_0994|M.thermoresistible__bu KEGIGLRAMAQRDPLVXXWRPRVGQSRALSRRQACLDPTSRGDEDLAVPV MAV_2894|M.avium_104 RESIHLRALGRQNPLDEFHRL----------------------------- :*.* **.:.:: * * Mflv_4705|M.gilvum_PYR-GCK V-AAP-TVAAQAAPSGLAEFAAAAAQQ----------GSVATKERP---- Mvan_1762|M.vanbaalenii_PYR-1 APSAP-TVAAQAAPAGLAAFAAAAAEQA-----QAQTGGVATKERPA--- MSMEG_1881|M.smegmatis_MC2_155 APQQP-QVAPQAPPPTLSEFAAAAAAKASDSAAKPDSGSVATKERAEAER Mb3268c|M.bovis_AF2122/97 VPAP--PVAPAAEPAELAEFAAAAAAAAQ-------QRSA--VDGGARER Rv3240c|M.tuberculosis_H37Rv VPAP--PVAPAAEPAELAEFAAAAAAAAQ-------QRSA--VDGGARER MLBr_00779|M.leprae_Br4923 VPAS--HVAPVEIPEGFTGLVADVEAIR------------------PREE MMAR_1305|M.marinum_M VPAPQVEVAPVAEPEDLAEFATAAAAAAQ-------EGGAGPKTAAAREE MUL_2576|M.ulcerans_Agy99 VPAPQVEVAPVAEPEDLAEFATAAAAAAQ-------EGGAGRKNAAAREE MAB_3580c|M.abscessus_ATCC_199 QQPDGAAVAPQEAPEGLAEFASAAAQAAH-------G------------- TH_0994|M.thermoresistible__bu GVCQFVERRGDAVQADLAGDQRRHIDVAVG---------------DRAQR MAV_2894|M.avium_104 ------------AVDAFASLAADAIEAAQ--------------------- :: Mflv_4705|M.gilvum_PYR-GCK -TGGLRAKGIDDQSRPLTYTGPSEDGTPEVKRSENAP-----AASTGMTR Mvan_1762|M.vanbaalenii_PYR-1 -VGGLRAKGIDDKAQPLTYTGPSEDGGVEVKRSGGG------TPSTGGTR MSMEG_1881|M.smegmatis_MC2_155 PAPALRAKGIDNEAPPLTYTGPSEDGTAQVQRSGNGGR---HAAPAGGSR Mb3268c|M.bovis_AF2122/97 APSALRAKGVASESPALTYSGPAEDGSAQVQRNGGGAHKTPAGVPAGASR Rv3240c|M.tuberculosis_H37Rv APSALRAKGVASESPALTYSGPAEDGSAQVQRNGGGAHKTPAGVPAGASR MLBr_00779|M.leprae_Br4923 ASSALRTKDIDNESTGLTYSGPSEDGSTQVQLNSGGGQKTPAGIPVGASR MMAR_1305|M.marinum_M APSRLRAKGIEDESPALTYSGPSEDGSAQVQRNGGGAAKTPAGVPAGGSR MUL_2576|M.ulcerans_Agy99 APSRLRAKGIEDESPALTYSGPSEDGSAQVQRNGGGAAKTPAGVPAGRSR MAB_3580c|M.abscessus_ATCC_199 ---ELRAKGLEESTPELTYSGPAEDGSAQSRHENG-----AASASGGGTR TH_0994|M.thermoresistible__bu FGELGRVVGVDEGDADLLGGAEERQHGVGFHAHPGDD----HPGPLWGPA MAV_2894|M.avium_104 --QTFETANVLEDEPGLDLSKLAR--------------------PTSTWT .. .: . * . . Mflv_4705|M.gilvum_PYR-GCK KERREAARQQQKAGRHAKRG--- Mvan_1762|M.vanbaalenii_PYR-1 KERREAARQQ-KTGRHAKRR--- MSMEG_1881|M.smegmatis_MC2_155 RERREAARKQAKADRPAKSHRKG Mb3268c|M.bovis_AF2122/97 RERREAARRQGRGAKPPKSVKKR Rv3240c|M.tuberculosis_H37Rv RERREAARRQGRGAKPPKSVKKR MLBr_00779|M.leprae_Br4923 RERREAARRRGRGAKPSRSVKKR MMAR_1305|M.marinum_M RERREAARRQGRGAKPPKSVKKR MUL_2576|M.ulcerans_Agy99 RERREAARRQGRGAKPPKSVKKR MAB_3580c|M.abscessus_ATCC_199 RERREAARNAGRTSKPAKSRRKR TH_0994|M.thermoresistible__bu QHIVEDAGHADRLEHHRRAGGER MAV_2894|M.avium_104 YMVNDNPLSDDTLSTLSLPGVFR : .