For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_1265 (-)

SGHVFIINGDLTKIACDAVLVPTDDHFTIEAPWRGLFEGRRHEIPETWGTERVLALPPRKNEPQIWLGNV
GQVGDSSDFSVFAPIVRDFVVNARTELKSVANEDRIYAWPKPRLALNVVGSGRGGGSEKKGHLVLGLVKT
LTALADENDVDIVLVTFGPKPYAAAQRARRHFVHKEEDVWRFHEEANSDLIKEAHRLADEAIKRHLVLFV
GAGASAGAGLPTWKGLLDRFAEEAGFDKATRERLTERDFRDQATLIERELKRRDVDLKDGVAAEFRGFER
FSLTHGLLASLPSSEAVTTNYDNLFETAYKTRGRDVAVLPENPRTTEGHWLLKLHGSVDQPEKIILTRSD
YLSMPRQYGALMGLVQGLLLMRRMVFVGYSLSDEDFHELIDEVRAARGDSETGLGRGVALTLYADPLDRQ
LWEKDLDIVPMITGTQVEAPVAARELELFLDLVGYLSTTSASFFLDASYSDLSDNEAELRDALAALAIKT
AGSPLDSVGHLVEEFLKDLGA*

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. smegmatis MC2 155	MSMEG_1265	-	-	100% (512)	hypothetical protein MSMEG_1265

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. gilvum PYR-GCK	-	-	-	-	-
M. tuberculosis H37Rv	-	-	-	-	-
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	-	-	-	-	-
M. marinum M	MMAR_3381	-	1e-141	54.41% (533)	hypothetical protein MMAR_3381
M. avium 104	-	-	-	-	-
M. thermoresistible (build 8)	-	-	-	-	-
M. ulcerans Agy99	MUL_2693	-	1e-118	57.82% (422)	hypothetical protein MUL_2693
M. vanbaalenii PYR-1	-	-	-	-	-

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_3381|M.marinum_M               MGGHLFIIDGDLTKIACDAILIPTDDDFRINNHWATFLGDDHQLELAQLR
MUL_2693|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_1265|M.smegmatis_MC2_155      MSGHVFIINGDLTKIACDAVLVPTDDHFTIEAPWRGLFEGR--------R
                                                                                      

MMAR_3381|M.marinum_M               QNPARGWGSSTVKPLECVAEKPQVWLGKIGRADGQLDFTKLDPSVTEFVK
MUL_2693|M.ulcerans_Agy99           MRPAP-------------------------------------------VK
MSMEG_1265|M.smegmatis_MC2_155      HEIPETWGTERVLALPPRKNEPQIWLGNVGQVGDSSDFSVFAPIVRDFVV
                                     . .                                            * 

MMAR_3381|M.marinum_M               MATEEAKS-RNVNPIYNWPLPRLAVNIVGSDHGGGSQKKGHLVRGLVHTL
MUL_2693|M.ulcerans_Agy99           MAIEEAKS-RNVNPIYNWPLPRLAVNIVGSDHGGGSQKKGHLVRGLVHTL
MSMEG_1265|M.smegmatis_MC2_155      NARTELKSVANEDRIYAWPKPRLALNVVGSGRGGGSEKKGHLVLGLVKTL
                                     *  * **  * : ** ** ****:*:***.:****:****** ***:**

MMAR_3381|M.marinum_M               SDLANEHGVDIVLVAFGAKSYAAAQRARRQRIGVGDENLRLAWPFENAPV
MUL_2693|M.ulcerans_Agy99           SDLANEHGVDIVLVAFGAKSYAAAQRARRQRIEVGDENLRLAWPFENAPV
MSMEG_1265|M.smegmatis_MC2_155      TALADENDVDIVLVTFGPKPYAAAQRARRHFVHKEEDVWRFH---EEANS
                                    : **:*:.******:**.*.*********: :   ::  *:    *:*  

MMAR_3381|M.marinum_M               DLLAAARELAHQAINSHLVLFVGAGVSMGAGLQPWKDLLRDVAATEAMFT
MUL_2693|M.ulcerans_Agy99           DLLAAARELAHQAINSHLVLFVGAGVSMGAGLQPWKDLLRDVAATEAMFT
MSMEG_1265|M.smegmatis_MC2_155      DLIKEAHRLADEAIKRHLVLFVGAGASAGAGLPTWKGLL-DRFAEEAGFD
                                    **:  *:.**.:**: *********.* **** .**.** *  * ** * 

MMAR_3381|M.marinum_M               DHALEQLAKRDPRDQATILERRLESLATTLKT-VVARRLEKPCYALAHGL
MUL_2693|M.ulcerans_Agy99           DHALEQLAKRDPRDQATILERRLESLATTLKT-VVARRLEKPCYALAHGL
MSMEG_1265|M.smegmatis_MC2_155      KATRERLTERDFRDQATLIERELKRRDVDLKDGVAAEFRGFERFSLTHGL
                                    . : *:*::** *****::**.*:   . **  *.*.      ::*:***

MMAR_3381|M.marinum_M               LASLPSKEAVTTNFDELFETAWTTGNRSLAILPDSAVDTGGRWLLKLHGS
MUL_2693|M.ulcerans_Agy99           LASLPSKEAVTTNFDELFETAWTTGNRSLAILPDSAVDTGGRWLLKLHGS
MSMEG_1265|M.smegmatis_MC2_155      LASLPSSEAVTTNYDNLFETAYKTRGRDVAVLPENPRTTEGHWLLKLHGS
                                    ******.******:*:*****:.* .*.:*:**:..  * *:********

MMAR_3381|M.marinum_M               VTESHKMILTRSDYLDMPRQYGALIGLVQGLLMMRHMMFVGYSLQDEDFH
MUL_2693|M.ulcerans_Agy99           VTESHKMILTRSDYLDMPRQYGALIGLVQGLLMMRHMMFVGYSLQDEDFH
MSMEG_1265|M.smegmatis_MC2_155      VDQPEKIILTRSDYLSMPRQYGALMGLVQGLLLMRRMVFVGYSLSDEDFH
                                    * :..*:********.********:*******:**:*:******.*****

MMAR_3381|M.marinum_M               ELIHEVRVAQGYKDGLKLRGTVLTLQEDELDRDLWRQDLVIVPMSK-PRV
MUL_2693|M.ulcerans_Agy99           ELIHEVRVAQGYKDGLKLRGTVLTLQEDELDRDLWRQDLVIVPMSK-PRV
MSMEG_1265|M.smegmatis_MC2_155      ELIDEVRAARGDSETGLGRGVALTLYADPLDRQLWEKDLDIVPMITGTQV
                                    ***.***.*:* .:    **..***  * ***:**.:** **** . .:*

MMAR_3381|M.marinum_M               SLEVASRQLEMFLDLVGYLSATSAAFFLDETYDELSKDETILRDALNQLV
MUL_2693|M.ulcerans_Agy99           SLEVASRQLEMFLDLVGYLSATSAAFFLDETYDELSKDETILRDALNQLV
MSMEG_1265|M.smegmatis_MC2_155      EAPVAARELELFLDLVGYLSTTSASFFLDASYSDLSDNEAELRDALAALA
                                    .  **:*:**:*********:***:**** :*.:**.:*: *****  *.

MMAR_3381|M.marinum_M               EHLDGDPKSREDDTVAYKVRHFLREELGADVKDVPN
MUL_2693|M.ulcerans_Agy99           EHLDGDPKSREDDTVAYKVRHFLREELGADVKDVPN
MSMEG_1265|M.smegmatis_MC2_155      IKTAGSP----LDSVGHLVEEFL-KDLGA-------
                                     :  *.*     *:*.: *..** ::***