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M. smegmatis MC2 155 MSMEG_1172 (arsB)

annotation: arsenical-resistance protein
coordinates: 1232924 - 1234000
length: 358

TTTSTTATVVGKLSTLDRFLPVWIGAAMAAGLLLGRWIPGLNTALESIQVDGISLPIALGLLIMMYPVLA
KVRYDRLDTVTGDRKLLASSLILNWALGPALMFTLAWLLLPDLPEYRTGLIIVGLARCIAMVIIWNDLAC
GDREAAAVLVALNSIFQVVMFAVLGWFYLSVLPGWLGLEQATITTSPWQIARSVLIFLGIPLAAGYLSRR
IGEKARGREWYESRFLPRVGPWALYGLLFTIVVLFALQGEQITSRPLDVVRIALPLLVYFAIMWGGGYLL
GAVLGLSYERTTTLAFTAAGNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVALVYVSLALRKRFN
RAKEHTS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_1172arsB-100% (358)arsenical-resistance protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2676arsC1e-17789.11% (349) arsenic-transport integral membrane protein ArsC
M. gilvum PYR-GCKMflv_3469-1e-17385.88% (347) arsenical-resistance protein
M. tuberculosis H37RvRv2643arsC1e-17789.11% (349) arsenic-transport integral membrane protein ArsC
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4863-1e-17786.15% (361) arsenic-transport integral membrane protein ArsC
M. marinum MMMAR_2055arsC1e-17689.44% (341) arsenic-transport integral membrane protein ArsC
M. avium 104MAV_1495arsB1e-17685.92% (348) arsenical-resistance protein
M. thermoresistible (build 8)TH_1048arsC1e-17588.20% (339) PROBABLE ARSENIC-TRANSPORT INTEGRAL MEMBRANE PROTEIN ARSC
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_3222-1e-17888.32% (351) arsenical-resistance protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb2676|M.bovis_AF2122/97            MTETVTRTAAPAVVGKLSTLDRFLPVWIGSAMAAGLLLGRWIPGLHTALE
Rv2643|M.tuberculosis_H37Rv         MTETVTRTAAPAVVGKLSTLDRFLPVWIGSAMAAGLLLGRWIPGLHTALE
MMAR_2055|M.marinum_M               MTGTVDHQPAPAVVGKLSTLDRFLPVWIGLAMAAGLLLGRWIPGLNTALE
TH_1048|M.thermoresistible__bu      ----------------MSVLDRYLTVWIGAAMIAGLLLGRWIPGLNTALE
Mvan_3222|M.vanbaalenii_PYR-1       --MSDTSTASPAVVAKLSTLDRFLPLWIGAAMVAGLLLGRWIPGLNTALE
MSMEG_1172|M.smegmatis_MC2_155      MTTTSTTAT---VVGKLSTLDRFLPVWIGAAMAAGLLLGRWIPGLNTALE
MAB_4863|M.abscessus_ATCC_1997      MNATADTAEHPAVAGKLSTLDRFLPVWIGVAMAAGLLLGRNVPGLNTALE
MAV_1495|M.avium_104                -MNSPTTTDPTPVVGKLSTLDRFLPVWIGAAMVAGLLLGRAVPGLDRALS
Mflv_3469|M.gilvum_PYR-GCK          MSQQVESGPDHAVVGKLSTLDRFLPVWIIAAMIAGLLLGRMVPGFDTALN
                                                    :*.***:*.:**  ** ******* :**:. **.

Mb2676|M.bovis_AF2122/97            GVQLDGISLPIALGLLIMMYPVLAKVRYDRLDTVTGDRKLLLSSLLLNWV
Rv2643|M.tuberculosis_H37Rv         GVQLDGISLPIALGLLIMMYPVLAKVRYDRLDTVTGDRKLLLSSLLLNWV
MMAR_2055|M.marinum_M               KVQVDGISLPIALGLLIMMYPVLAKVRYDRLDSVTGDRKLLISSLLLNWV
TH_1048|M.thermoresistible__bu      SVAIDGISLPIALGLLIMMYPVLAKVRYDRLDTVTGDRRLLLSSLVLNWV
Mvan_3222|M.vanbaalenii_PYR-1       SVAIDGVSLPIALGLLIMMYPVLAKVRYDRLDTVTGDRRLLISSLVLNWV
MSMEG_1172|M.smegmatis_MC2_155      SIQVDGISLPIALGLLIMMYPVLAKVRYDRLDTVTGDRKLLASSLILNWA
MAB_4863|M.abscessus_ATCC_1997      KVQVDGISLPIALGLLIMMYPVLAKVRYDRLDTVTGDRKLLLGSLVLNWV
MAV_1495|M.avium_104                AVQLDGISLPIAIGLLVMMYPVLAKVRYDRLDAVTGDRKLMVASLVLNWV
Mflv_3469|M.gilvum_PYR-GCK          SAQVQGISIPIAVGLLVMMYPVLAKVRYDRLGTVTGDRRLLVSSLVLNWV
                                       ::*:*:***:***:**************.:*****:*: .**:***.

Mb2676|M.bovis_AF2122/97            LGPALMFALAWLLLADLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAA
Rv2643|M.tuberculosis_H37Rv         LGPALMFALAWLLLADLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAA
MMAR_2055|M.marinum_M               AGPALMFALAWLLLPDLPEYRTGLIIVGLARCIAMVIIWNDLARGDREAA
TH_1048|M.thermoresistible__bu      FGPALMFALAWLLLPDLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAA
Mvan_3222|M.vanbaalenii_PYR-1       FGPALMFALAWLMLPDLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAA
MSMEG_1172|M.smegmatis_MC2_155      LGPALMFTLAWLLLPDLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAA
MAB_4863|M.abscessus_ATCC_1997      LGPALMFALAWLLLPDLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAA
MAV_1495|M.avium_104                IGPALMFALAWLLLPDLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAA
Mflv_3469|M.gilvum_PYR-GCK          LGPALMFALAWLLVPDLPEYRTGLIIVGLARCIAMVIIWNDLACGDREAA
                                     ******:****::.**************************** ******

Mb2676|M.bovis_AF2122/97            AVLVALNSIFQVAMFAALGWFYLSVLPGWLGLEQTTIATSPWQIAKSVLI
Rv2643|M.tuberculosis_H37Rv         AVLVALNSIFQVAMFAALGWFYLSVLPGWLGLEQTTIATSPWQIAKSVLI
MMAR_2055|M.marinum_M               AVLVALNSIFQVAMFAVLGWFYLSVLPGWLHLTQTTISTSPWQIAKSVLI
TH_1048|M.thermoresistible__bu      AVLVALNSIFQVIMFAVLGWFYLSVLPGWLGLEQTTIDTSPWQIAKSVLI
Mvan_3222|M.vanbaalenii_PYR-1       AVLVALNSIFQVFMFAVLGWFYLSVLPGWLGLEQTTIDTSPWQIAKSVLI
MSMEG_1172|M.smegmatis_MC2_155      AVLVALNSIFQVVMFAVLGWFYLSVLPGWLGLEQATITTSPWQIARSVLI
MAB_4863|M.abscessus_ATCC_1997      AVLVALNSVFQVVMFAVLGWFYLSVLPGWLHLPQTEISTSPWQIAKSVLI
MAV_1495|M.avium_104                AVLVALNSVFQVVMFAVLGWFYLSVLPGWLGLDQTSISVSPWQIAKSVLI
Mflv_3469|M.gilvum_PYR-GCK          AVLVALNSLFQVVMFAVLGWFYLAVLPGWLGLETASIDASPWEIAQSVLI
                                    ********:*** ***.******:****** *  : * .***:**:****

Mb2676|M.bovis_AF2122/97            FLGIPLLAGYLSRRIGEKTKGRNWYESRFLPKVGPWALYGLLFTIVILFA
Rv2643|M.tuberculosis_H37Rv         FLGIPLLAGYLSRRIGEKTKGRNWYESRFLPKVGPWALYGLLFTIVILFA
MMAR_2055|M.marinum_M               FLGIPLLAGYLSRRLGERAKGRGWYESRFLPKVGPWALYGLLFTIVILFA
TH_1048|M.thermoresistible__bu      FLGIPLLAGYLSRRVGERTKGRDWYESIFLPRVSPWALYGLLFTVVILFA
Mvan_3222|M.vanbaalenii_PYR-1       FLGIPLLAGYLSRRIGEKTKGRAWYESRFLPVIGPWALYGLLFTIVILFA
MSMEG_1172|M.smegmatis_MC2_155      FLGIPLAAGYLSRRIGEKARGREWYESRFLPRVGPWALYGLLFTIVVLFA
MAB_4863|M.abscessus_ATCC_1997      FLGIPLLAGYLSRSIGERTRGRDWYESKFLPVIGPWALYGLLFTIVILFA
MAV_1495|M.avium_104                FLGVPLLLGYLSRRLGERTKGRDWYEDRFLPKVGPWALYGLLFTIVILFA
Mflv_3469|M.gilvum_PYR-GCK          FLGIPLLAGYLTRRLGEKAKGRTWYETRFLPRIGPWALYGLLFTIVVLFA
                                    ***:**  ***:* :**:::** ***  *** :.**********:*:***

Mb2676|M.bovis_AF2122/97            LQGDQITGRPLDVARIALPLLAYFAIMWVGGYLLGAALRLGYRRTTTLAF
Rv2643|M.tuberculosis_H37Rv         LQGDQITGRPLDVARIALPLLAYFAIMWVGGYLLGAALRLGYRRTTTLAF
MMAR_2055|M.marinum_M               LQGDQITNRPQDVARIALPLLVYFAVMWGGGYLLGAALHLGYQRTTTMAF
TH_1048|M.thermoresistible__bu      LQGDQITNRPLDVTRIALPLLAYFTIMWGGGYLTGAALGLGYERTTTLAF
Mvan_3222|M.vanbaalenii_PYR-1       LQGDQITNRPWDVARIALPLLVYFAVMWGGGYALGAALRLGYERTTTLAF
MSMEG_1172|M.smegmatis_MC2_155      LQGEQITSRPLDVVRIALPLLVYFAIMWGGGYLLGAVLGLSYERTTTLAF
MAB_4863|M.abscessus_ATCC_1997      LQGDQITSKPWDVARIALPLLAYFAIMWGGGYLLGAAMGLGYARTTTLAF
MAV_1495|M.avium_104                LQGAQITSRPLDVVRIAVPLLVYFAVMWGGGYALGAVLGLGYQRTTTLAF
Mflv_3469|M.gilvum_PYR-GCK          LQGQQITSRPLDVARIALPLLVYFAVMWGGGYLLGAALGLGYRRTTTLAF
                                    *** ***.:* **.***:***.**::** ***  **.: *.* ****:**

Mb2676|M.bovis_AF2122/97            TAASNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLALR
Rv2643|M.tuberculosis_H37Rv         TAASNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLALR
MMAR_2055|M.marinum_M               TAAGNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVGLVYVSLALR
TH_1048|M.thermoresistible__bu      TAAGNNFELAIAVAIATYGATSGQALATVVGPLIEVPVLVALIYVSLALR
Mvan_3222|M.vanbaalenii_PYR-1       TAAGNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVALVYVSLALR
MSMEG_1172|M.smegmatis_MC2_155      TAAGNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVALVYVSLALR
MAB_4863|M.abscessus_ATCC_1997      TAAGNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVALVYVSLALR
MAV_1495|M.avium_104                TAAGNNFELAIAVAIATYGATSGQALAGVVGPLIEVPVLVALVYVSLALR
Mflv_3469|M.gilvum_PYR-GCK          TAAGNNFELAIAVCIATYGATSGQALAGVVGPLIEVPVLVALVYVSLFLR
                                    ***.*********.************* ************.*:**** **

Mb2676|M.bovis_AF2122/97            NRLAGPN-ATHDADKPSVLFVCVHNAGRSQMAAGLLTHLAGDRIEVRSAG
Rv2643|M.tuberculosis_H37Rv         NRLAGPN-ATHDADKPSVLFVCVHNAGRSQMAAGLLTHLAGDRIEVRSAG
MMAR_2055|M.marinum_M               NRYYGPHRRKHDMIKPSVLFVCVHNAGRSQMAAGWLRHLAGDRIEVRSAG
TH_1048|M.thermoresistible__bu      QRFERTP-----------------------LAP-----------------
Mvan_3222|M.vanbaalenii_PYR-1       RRFPDST-----------------------TDSTRTKEVVDD--------
MSMEG_1172|M.smegmatis_MC2_155      KRFNRAK-----------------------EHTS----------------
MAB_4863|M.abscessus_ATCC_1997      GRFTPAP-----------------------QHNSPAASTAASTTNVTE--
MAV_1495|M.avium_104                RRFKSST-----------------------PESIPTTDRNTP--------
Mflv_3469|M.gilvum_PYR-GCK          RRFHAGS------------------------DNRPREDATDG--------
                                     *                                                

Mb2676|M.bovis_AF2122/97            TEPAGQVNPTAVAAMAEMGIDITANAPTLLTGGQVQSSDVVITMGCGDAC
Rv2643|M.tuberculosis_H37Rv         TEPAGQVNPTAVAAMAEMGIDITANAPTLLTGGQVQSSDVVITMGCGDAC
MMAR_2055|M.marinum_M               TEPADRINPVAVAAMAELGIDITANTPEVLTGAWVQTSDVVITMGCGDAC
TH_1048|M.thermoresistible__bu      --------------------------------------------------
Mvan_3222|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1172|M.smegmatis_MC2_155      --------------------------------------------------
MAB_4863|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1495|M.avium_104                --------------------------------------------------
Mflv_3469|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

Mb2676|M.bovis_AF2122/97            PYFPGASYRNWKLPDPAGQPLDVVRMIRDDIADRVQALIAELLATAKTR-
Rv2643|M.tuberculosis_H37Rv         PYFPGVSYRNWKLPDPAGQPLDVVRMIRDDIADRVQALIAELLATAKTR-
MMAR_2055|M.marinum_M               PYFPGVSYRDWTLADPAGQPLDVVRPIRDDIGERVRALIAELLNEHPDTA
TH_1048|M.thermoresistible__bu      --------------------------------------------------
Mvan_3222|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1172|M.smegmatis_MC2_155      --------------------------------------------------
MAB_4863|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_1495|M.avium_104                --------------------------------------------------
Mflv_3469|M.gilvum_PYR-GCK          --------------------------------------------------
                                                                                      

Mb2676|M.bovis_AF2122/97            -----
Rv2643|M.tuberculosis_H37Rv         -----
MMAR_2055|M.marinum_M               QICRG
TH_1048|M.thermoresistible__bu      -----
Mvan_3222|M.vanbaalenii_PYR-1       -----
MSMEG_1172|M.smegmatis_MC2_155      -----
MAB_4863|M.abscessus_ATCC_1997      -----
MAV_1495|M.avium_104                -----
Mflv_3469|M.gilvum_PYR-GCK          -----