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M. smegmatis MC2 155 MSMEG_0756 (-)

annotation: peptidase, M50B family protein
coordinates: 842699 - 843478
length: 259

NIRPLRQSVRPSPIFLLVIAVTAAGGALAWIAADTIRPLSYVGVFILVIAGWLMSLCLHEFGHAFTAWRF
GDHGVETRGYLTLNPLKYTHPMLSLGLPVLIIALGGIGFPGGAVYLQTHWMTARQKSIVSLAGPAANLVL
AVLLLGLTRAFWDPAHAVFWSGIAFLGFLQVTALVLNLLPIPGLDGYGALEPHLNPETQRALAPAKQWGF
LIVVVLLITPALNRWFFELVYWFFDFSGVSSYLVSAGGQLTRFWSAWF*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0756--100% (259)peptidase, M50B family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0366-1e-10669.17% (253) integral membrane protein
M. gilvum PYR-GCKMflv_0230-1e-11274.30% (249) peptidase M50
M. tuberculosis H37RvRv0359-1e-10668.77% (253) integral membrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4251-3e-9262.55% (251) hypothetical protein MAB_4251
M. marinum MMMAR_0678-1e-10166.80% (253) hypothetical protein MMAR_0678
M. avium 104MAV_4781-1e-10769.69% (254) peptidase, M50 family protein
M. thermoresistible (build 8)TH_0137-1e-10767.44% (258) PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
M. ulcerans Agy99MUL_2836-5e-9965.22% (253) hypothetical protein MUL_2836
M. vanbaalenii PYR-1Mvan_0674-1e-11472.87% (258) peptidase M50

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0230|M.gilvum_PYR-GCK          --MVS-LVG-VRPSPVFAALVAVTAAGGALAWTSGDDVRPLSYAAVFVLV
Mvan_0674|M.vanbaalenii_PYR-1       MSVRP-LHQSVRPSPIFLALVAVTAAGGALAWTSAGRIEPVAYIGVFVFV
TH_0137|M.thermoresistible__bu      VSIRS-VSGSVRPSPVFLAIVALTAAGGGLAWASATVTGPAAYAGVFLFV
MSMEG_0756|M.smegmatis_MC2_155      MNIRP-LRQSVRPSPIFLLVIAVTAAGGALAWIAADTIRPLSYVGVFILV
Mb0366|M.bovis_AF2122/97            MSETG-QRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMV
Rv0359|M.tuberculosis_H37Rv         MSETG-QRESVRPSPIFLGLLGLTAVGGALAWLAGETVQPLAYAGVFVMV
MMAR_0678|M.marinum_M               ---MG-LHESVRPSPIFLGLVGLTTVGAALAWLAGSSVRPLAYAGVFVFV
MUL_2836|M.ulcerans_Agy99           MSEMG-LHESVRPSPIFLGLVGLTTVGAALAWLTGSSVRPLAYAGVFVFA
MAV_4781|M.avium_104                MSFRAPQHESVRPSPIFLALLGLTALGGALAWLAGSSPRPLAYLGVFVFV
MAB_4251|M.abscessus_ATCC_1997      ---MN-VKQSVRPSPVFLVLVALTVAGAVFAWLGGDSTEPLARGGVFVFV
                                              *****:*  ::.:*. *. :**  .    * :  .**::.

Mflv_0230|M.gilvum_PYR-GCK          IFGWLVTLCLHEFGHAYSAYRFGDRDVAVRGYLTLNPLKYTHPLLSLGLP
Mvan_0674|M.vanbaalenii_PYR-1       IFGWLVTLCLHEFGHAYSAYRFGDRDVAVRGYLTLNPLKYSHPLLSLGLP
TH_0137|M.thermoresistible__bu      IAGWLVTLCLHEFAHAWSAWRFGDREVAARGYLTLNPLRYTHPLLSIGLP
MSMEG_0756|M.smegmatis_MC2_155      IAGWLMSLCLHEFGHAFTAWRFGDHGVETRGYLTLNPLKYTHPMLSLGLP
Mb0366|M.bovis_AF2122/97            IAGWLVSLCLHEFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLP
Rv0359|M.tuberculosis_H37Rv         IAGWLVSLCLHEFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPMLSLGLP
MMAR_0678|M.marinum_M               IAGWLVSLCLHEFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPALSLLLP
MUL_2836|M.ulcerans_Agy99           IAGWLVSLCLHEFGHAFTAWRFGDHDVAVRGYLTLDPRRYSHPALSLLLP
MAV_4781|M.avium_104                IAGWLVSLCLHEFGHAVTAWRFGDRDAAVRGYLTLDPRRYSHPALSLVLP
MAB_4251|M.abscessus_ATCC_1997      FAGWIVSLCLHEFGHAYTAWRFG--DTQARGYLTLNPLQYTDPVLSIALP
                                    : **:::******.** :*:***   . .******:* :*:.* **: **

Mflv_0230|M.gilvum_PYR-GCK          VLFIALGGIGLPGGAVYVQTALMTDRQKTVVSLAGPAVNLLFAVLLLGLT
Mvan_0674|M.vanbaalenii_PYR-1       VLFIALGGIGLPGGAVYVQTAHMTDRQKTLVSLAGPGVNLIFAVLLLALT
TH_0137|M.thermoresistible__bu      VLFVALGGIGFPGGAVDVRTHRMTPWRQSVVSLAGPSVNLVFAALLLTLT
MSMEG_0756|M.smegmatis_MC2_155      VLIIALGGIGFPGGAVYLQTHWMTARQKSIVSLAGPAANLVLAVLLLGLT
Mb0366|M.bovis_AF2122/97            MLFIALGGIGLPGAAVYVHTWFMTTARRTLVSLAGPTVNLALAMLLLAAT
Rv0359|M.tuberculosis_H37Rv         MLFIALGGIGLPGAAVYVHTWFMTTARRTLVSLAGPTVNLALAMLLLAAT
MMAR_0678|M.marinum_M               MVFIALGGIGLPGAAVYVRTWFMTPTRRTLVSLAGPAANVVLAVLLLTAT
MUL_2836|M.ulcerans_Agy99           MVFIALGGIGLPGAAVYVRTWFMTPTRRTLVSLAGPAANVVLAVLLLTAT
MAV_4781|M.avium_104                MVIIALGGIGLPGAAVYVQTWFMTPARRTLVSLAGPAANLVLAAVLLALT
MAB_4251|M.abscessus_ATCC_1997      LVFIALGGIGLPGGAVYVHTAGMTNRQRTIVSLAGPTANAILAVLILGTT
                                    ::::******:**.** ::*  **  ::::****** .*  :* ::*  *

Mflv_0230|M.gilvum_PYR-GCK          RPMYDPAHAVFWAGVAFLGFLQVTAFVLNMLPIPGLDGYGALEPHLSPET
Mvan_0674|M.vanbaalenii_PYR-1       RLLYDPAHSVFWAGVAFLGFLQVTALLLNMLPIPGLDGYGALEPHLSPDT
TH_0137|M.thermoresistible__bu      RLCYDPAHGVFWAGVAFLGFLQITALVLNLLPIPGLDGFGALEPHLSPPT
MSMEG_0756|M.smegmatis_MC2_155      RAFWDPAHAVFWSGIAFLGFLQVTALVLNLLPIPGLDGYGALEPHLNPET
Mb0366|M.bovis_AF2122/97            RLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPGLDGYAALEPHLRPET
Rv0359|M.tuberculosis_H37Rv         RLLFDPIHAVLWAGVAFLAFLQLTALVLNLLPIPGLDGYAALEPHLRPET
MMAR_0678|M.marinum_M               RLFYDQDHWVLWAGVAFLGFLQIMAVVLNLLPIPGLDGYDALEPHLSPQT
MUL_2836|M.ulcerans_Agy99           RLFYDQDHWVLWAGVAFLGFLQIMAVVLKLLPIPGLDGYDALEPHLSPQT
MAV_4781|M.avium_104                RAFFTADHAVLWAGVAFLGFLQLTAVLLNLLPIPGLDGYDALEPHLSPET
MAB_4251|M.abscessus_ATCC_1997      ALFADREHVVFWAAMAYLGFLQVTAVVLNLLPVPGLDGYGALEPHLSPNT
                                           * *:*:.:*:*.***: *.:*::**:*****: ****** * *

Mflv_0230|M.gilvum_PYR-GCK          RRALAPARQWGFFILLILLIAPPLNQWFFAAVYWLFELSGVDVYLSQLGG
Mvan_0674|M.vanbaalenii_PYR-1       QRALNPAKQWGFFILLILLIAPPLNQWFFGAVYWLFELSGVPPALSAIGG
TH_0137|M.thermoresistible__bu      RRAVQPAKQWGFLILIVLLLTPTLNQWFFSAVHWLYELSGAPGALSAAGS
MSMEG_0756|M.smegmatis_MC2_155      QRALAPAKQWGFLIVVVLLITPALNRWFFELVYWFFDFSGVSSYLVSAGG
Mb0366|M.bovis_AF2122/97            QRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRLAAAGS
Rv0359|M.tuberculosis_H37Rv         QRALAPAKQFALVFLLVLFLAPTLNGWFFGVVYWLFDLSGVSHRLAAAGS
MMAR_0678|M.marinum_M               QRALAPAKQFGIFILLFLLLAPVLNQWLFEFVGWVFDFSGVPHLLAMVGN
MUL_2836|M.ulcerans_Agy99           QRALAPAKQFGIFILLFLLLAPVLNQWLFEFVGWVSDFSGVPHLLAMVGN
MAV_4781|M.avium_104                QRALAPAKQWGFFILLFLLLAPGLNRWFFGIVYWLFDFSGVPHWLAGAGN
MAB_4251|M.abscessus_ATCC_1997      QRTLGNAKTFGFLILFALLMSPPVNRAFFGAVYWIVAYLGVDPALAQIGG
                                    :*::  *: :.:.::. *:::* :*  :*  * *.    *.   *   *.

Mflv_0230|M.gilvum_PYR-GCK          GLTRFWSPWL
Mvan_0674|M.vanbaalenii_PYR-1       QLTRFWSAWT
TH_0137|M.thermoresistible__bu      RLTRFWSSWM
MSMEG_0756|M.smegmatis_MC2_155      QLTRFWSAWF
Mb0366|M.bovis_AF2122/97            VLTRFWSIWF
Rv0359|M.tuberculosis_H37Rv         VLARFWSIWF
MMAR_0678|M.marinum_M               SLTRFWSQWI
MUL_2836|M.ulcerans_Agy99           SLTRFWSQWI
MAV_4781|M.avium_104                VLTRFWSRWV
MAB_4251|M.abscessus_ATCC_1997      WLFRFWSKLL
                                     * ****