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PNPSEPNEDHTPSSEDPTEPSRQSADAPTEKVTLSSEHEPATEVFGLPTEPGQATPQGDERRFTAPSSFD GSTQKIDTPPDPETEVFAPPPGDPNKPVAPQVIPPRDDAARPQAPATARRSWGWVIAVVLVIAALVAIAI LGTVLLTRDSASAGSQEDRVRETIQKFDSAIQRGDLATLRSITCGTTRDNYVNYNEKAWAETHERVAAAK QYPVVASIDQVIVNDDHAEANVTTFMAFAPQTRSTRSFDLQFRDDEWKICQSPAF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0753 | - | - | 100% (266) | hypothetical protein MSMEG_0753 |
| M. smegmatis MC2 155 | MSMEG_5583 | - | 4e-06 | 31.58% (133) | HNH endonuclease |
| M. smegmatis MC2 155 | MSMEG_0767 | - | 2e-05 | 25.32% (158) | hypothetical protein MSMEG_0767 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0368 | - | 2e-69 | 53.24% (278) | hypothetical protein Mb0368 |
| M. gilvum PYR-GCK | Mflv_0233 | - | 9e-82 | 59.30% (258) | hypothetical protein Mflv_0233 |
| M. tuberculosis H37Rv | Rv0361 | - | 2e-69 | 53.24% (278) | hypothetical protein Rv0361 |
| M. leprae Br4923 | MLBr_00285 | - | 7e-63 | 46.94% (294) | hypothetical protein MLBr_00285 |
| M. abscessus ATCC 19977 | MAB_4253 | - | 6e-62 | 47.81% (274) | hypothetical protein MAB_4253 |
| M. marinum M | MMAR_0671 | - | 5e-76 | 55.20% (279) | hypothetical protein MMAR_0671 |
| M. avium 104 | MAV_4784 | - | 6e-73 | 53.48% (273) | hypothetical protein MAV_4784 |
| M. thermoresistible (build 8) | TH_1641 | - | 3e-89 | 63.27% (275) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2842 | - | 4e-76 | 55.20% (279) | hypothetical protein MUL_2842 |
| M. vanbaalenii PYR-1 | Mvan_0671 | - | 4e-86 | 61.90% (273) | hypothetical protein Mvan_0671 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0368|M.bovis_AF2122/97 MSNAPEPDRSA-------GESGSEPAGERSADPGEE---------RTESY
Rv0361|M.tuberculosis_H37Rv MSNAPEPDRSA-------GESGSEPAGERSADPGEE---------RTESY
MMAR_0671|M.marinum_M MPNAPEPDRDG-------TET-------RDAAAGEA---------GTESF
MUL_2842|M.ulcerans_Agy99 MPNAPEPDRDG-------TET-------RDAAAGEA---------GTESF
MAV_4784|M.avium_104 MPNPPEPGRGGPPKRPGFDPRASRASDEWTPETGEEPDGGFDSEDATESV
MLBr_00285|M.leprae_Br4923 MPNASEPERGITLNRPGLAPRTLDKNVVSNLPEAKDNPAMTHGEEIAAGY
MSMEG_0753|M.smegmatis_MC2_155 MPNPSEPNEDH-------TPSSEDPTEPSRQSADAPT---------EKVT
TH_1641|M.thermoresistible__bu MAHPPGSDREP-------GSDRESDTAGPDQSGAGPD---------APAT
Mflv_0233|M.gilvum_PYR-GCK MDKLRGMSNAP-------GPDGEDDAPAE---SSEAE---------TEVL
Mvan_0671|M.vanbaalenii_PYR-1 ------MSNAG-------GPDNSDQDPS----SAEPE---------TEVL
MAB_4253|M.abscessus_ATCC_1997 MANPTGGNSEA-------KPDARGEEPTESAEQPEG-----------AAN
Mb0368|M.bovis_AF2122/97 PLVPHDAETETVVITTSD--NDAAVTQPEAQRER-RFTAP-GFDAKETQV
Rv0361|M.tuberculosis_H37Rv PLVPHDAETETVVITTSD--NDAAVTQPEAQRER-RFTAP-GFDAKETQV
MMAR_0671|M.marinum_M PLIPDDTETETVVISKADPVTDPEPSGADAQPER-RFTAP-GFDAKETQV
MUL_2842|M.ulcerans_Agy99 PLIPDDTETETVVISKADPVTDPEPSGADAQPER-RFTAP-GFDAKETQV
MAV_4784|M.avium_104 PMVPSDAETETVVINKPDPPSGPQETPDGPQRER-RFTAP-GFDAKETTI
MLBr_00285|M.leprae_Br4923 PLAHSDSETEAMVLTKTE--PDQDPGADRQHHER-RFTAP-GFDARATAI
MSMEG_0753|M.smegmatis_MC2_155 LSS--EHEPATEVFGLPTEPGQAT----PQGDER-RFTAPSSFDG-STQK
TH_1641|M.thermoresistible__bu PPQEGDHEPATEVLANPSDQSDASSR--PQQPER-RFTAPSSFDAGSTQQ
Mflv_0233|M.gilvum_PYR-GCK PGTDAEHEPATEVFA-PAEPQDGDPS--DDAGER-RFTAPSGFDAGSTQV
Mvan_0671|M.vanbaalenii_PYR-1 SGADSEHEPATEVFA-PAEQQDEDP---DQPGER-RFTAPSGFDAGSTQV
MAB_4253|M.abscessus_ATCC_1997 APEVSDTEDNTDTGPVPPLDDAQTVVMAPAKPDVPRYTAP-GFDANKTEM
: * : . . : *:*** .**. *
Mb0368|M.bovis_AF2122/97 IVTAHEAATEVFQTNQAPTTPPRMPTGMPPKTAVPQSIPPRT-----EAT
Rv0361|M.tuberculosis_H37Rv IVTAHEAATEVFQTNQAPTTPPRMPTGMPPKTAVPQSIPPRT-----EAT
MMAR_0671|M.marinum_M IATAPEPATEVFQTHQAPPAGP-PPIGMPPKTAVPQSIPPRDS---GRPA
MUL_2842|M.ulcerans_Agy99 IATAPEPATEVFQTHQAPPAGP-PPIGMPPKTAVPQSIPPRDS---GRPA
MAV_4784|M.avium_104 IATTPEPATEAFVP---PGQDNTTQFGVPPKAAVPQSIPPRLG---GKLR
MLBr_00285|M.leprae_Br4923 MATAPDPATEAIHPPLSSSDPP-GHLGISPKAAVPQSIPPVLG---TKLR
MSMEG_0753|M.smegmatis_MC2_155 IDTPPDPETEVFAPP-------PGDPN---KPVAPQVIPPRDDAARPQAP
TH_1641|M.thermoresistible__bu IDPPADPATEVIGPAGAAAAAAPTEPIRSQKPVGPQVIPPRN---QPDPP
Mflv_0233|M.gilvum_PYR-GCK INRPHE---------------LPTEAFAAHKPAAPQMIPPRGE--TPKPP
Mvan_0671|M.vanbaalenii_PYR-1 INRPTDPATEQFSVHD---PGAPTEAFAPQKPAAPQMIPPRGD--APRPP
MAB_4253|M.abscessus_ATCC_1997 IDPVGDDPKTEFIQP--------LATQARPKAATPETIAPRKE-------
: : *.. *: *.*
Mb0368|M.bovis_AF2122/97 SVRQRTWGWALAVVVIVLALAAIAILGTVLLTRGKHSKMSQEDQVRQAIQ
Rv0361|M.tuberculosis_H37Rv SVRQRTWGWALAVVVIVLALAAIAILGTVLLTRGKHSKMSQEDQVRQAIQ
MMAR_0671|M.marinum_M ALKQRNWGWVLAIVVIVLALAAIAILGTVLLTRNKHPNVSQEDRVRQTIQ
MUL_2842|M.ulcerans_Agy99 ALKQRNWGWVLAIVVIVLALAAIAILGTVLLTRNKHPNVSQEDRVRQTIQ
MAV_4784|M.avium_104 TSRQINWGWILALVVIVLALAAIAILGTVLLTRGRHTNVSQEDQVRHTIG
MLBr_00285|M.leprae_Br4923 SARHFHWGWVVALLMMVLALAAIAILGTVLLTRGKHVKASPAEQVRHAIQ
MSMEG_0753|M.smegmatis_MC2_155 ATARRSWGWVIAVVLVIAALVAIAILGTVLLTRDSASAGSQEDRVRETIQ
TH_1641|M.thermoresistible__bu ERERRSWGWVIAVALVIAALAAVAILGTVLLTRDSVGRASQEDLVRQTIQ
Mflv_0233|M.gilvum_PYR-GCK KTGRRNWGWVIAIILVIAALAAAAVVGTLLLTRGSATSVSQEDSVRTAIQ
Mvan_0671|M.vanbaalenii_PYR-1 KK-KRNWGWVVAIVLVVAALAAVAILGTVLLTRGSGSSVSQEDRVRSTIE
MAB_4253|M.abscessus_ATCC_1997 --EKRSWGWVIALALVVAALAAVIVLAAVIISRTSTPKASQEELVRNSIQ
: *** :*: ::: **.* ::.:::::* * : ** :*
Mb0368|M.bovis_AF2122/97 SLDIAIQTGDLTALRSLTCGSTRDGYVDYDERDWAETYRRVSAAKQYPVI
Rv0361|M.tuberculosis_H37Rv SLDIAIQTGDLTALRSLTCGSTRDGYVDYDERDWAETYRRVSAAKQYPVI
MMAR_0671|M.marinum_M HFDAAVQTGDLTALRSITCGTTRDGYVDYDERSWDETYRRVSAAKQYPVI
MUL_2842|M.ulcerans_Agy99 HFDAAVQTGDLTALRSITCGTTRDGYVDYDERSWDETYRRVSAAKQYPVI
MAV_4784|M.avium_104 NFDAAIQRGDLTTLRSITCGTTRDGYADYDEHAWAETYRRVSAAKQYPVI
MLBr_00285|M.leprae_Br4923 SFDVAVQTGNLTALRSITCGTTRDGYVEYDESSWDETYHRVSAAKQYPVI
MSMEG_0753|M.smegmatis_MC2_155 KFDSAIQRGDLATLRSITCGTTRDNYVNYNEKAWAETHERVAAAKQYPVV
TH_1641|M.thermoresistible__bu TFDTAIQNGDLAILRSITCGSKRDSYVNYDEQAWADTHRRVAAAKQYPVV
Mflv_0233|M.gilvum_PYR-GCK NYDAAIEKGDLATLRSITCGATAESYNKFDERQWKDTHSRVAEAGRYPVV
Mvan_0671|M.vanbaalenii_PYR-1 NYDAAIEKGDLATLRSITCGTTAEAYNNIDDKKWIETHRRVADAGRYPVV
MAB_4253|M.abscessus_ATCC_1997 NYDNAIQTGNLAALRTITCGETRDGYVRYPDGEWSQTYQKVAAAKQYPVV
* *:: *:*: **::*** . : * : * :*: :*: * :***:
Mb0368|M.bovis_AF2122/97 ASIDQVVVNGAHAEANVTTFMAFDPQVRSTRSLDLQFRDDQWKICQSSSN
Rv0361|M.tuberculosis_H37Rv ASIDQVVVNGAHAEANVTTFMAFDPQVRSTRSLDLQFRDDQWKICQSSSN
MMAR_0671|M.marinum_M ASIDQVVVNGQHAEANITTFMAYDPQVRSTRSLDLQFRDDQWKICQSPSS
MUL_2842|M.ulcerans_Agy99 ASIDQVVVNGQHAEANITTFMAYDPQVRSTRSLDLQFRDDQWKICQSPSS
MAV_4784|M.avium_104 ASIDQVVVNGQHAEANVTTFMAYDPQVRSTRSLDLQYRDDQWKICQSASG
MLBr_00285|M.leprae_Br4923 ASIDQVVVNGQHAEANITTFMAYDPQVRSTRSLDLQFCDDQWKICQSPSG
MSMEG_0753|M.smegmatis_MC2_155 ASIDQVIVNDDHAEANVTTFMAFAPQTRSTRSFDLQFRDDEWKICQSPAF
TH_1641|M.thermoresistible__bu ASIDEIVINGDHAEANVTSFMAYDPQVRSTRSFDLQFRDDQWKICQAPG-
Mflv_0233|M.gilvum_PYR-GCK ASIDEIVINGDHAEANVTTFMAFAPQTRSTRSFDLQFRDDQWKICQAPQ-
Mvan_0671|M.vanbaalenii_PYR-1 ASIDQIVVNGDHAEANVTTFMAFAPQTRSTRSFDLQFRDDEWKICQAPQ-
MAB_4253|M.abscessus_ATCC_1997 ASIDEVVVNGEHAEANVTSFMAFAPQTRSSRSFDLQFRDNQWKICQSD--
****::::*. *****:*:***: **.**:**:***: *::*****: