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AQVNGRVWRSGQPAEDFSFSAISDYLADDDTLVWADIYDPDHQTLLDLAAELGLNTWAVEDAVAPKERTK ASVYKTHTFFTVYAIDILTSGGGTGSLLVKHRISAFVLPHGLITVRLPGLDGAAHEFDIHEVSRRFDDLG GQRYGVGSLVHGLLDVVVDGHFEAVEALDDAIEGLEDELFDDRGPNRGLQRRTFRLRKDLVELRRVVLPT REVVSTIQHRRLDSRTSPELDPLYADLYDHVLRASEWTESLRDMVTTVFETHLSLQDARLNTVMKKLTGW AAIIAVPTAITGFYGQNVTYPGVDTVAGFVTSSALIAVLVGLLYVMFKRRDWL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0111 | - | - | 100% (334) | putative magnesium transport protein |
| M. smegmatis MC2 155 | MSMEG_5056 | corA | 1e-28 | 28.30% (311) | magnesium and cobalt transport protein CorA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1271c | corA | 6e-29 | 29.07% (313) | magnesium/cobalt transporter CorA |
| M. gilvum PYR-GCK | Mflv_5126 | - | 1e-130 | 69.94% (336) | Mg2+ transporter protein, CorA family protein |
| M. tuberculosis H37Rv | Rv1239c | corA | 6e-29 | 29.07% (313) | magnesium/cobalt transporter CorA |
| M. leprae Br4923 | MLBr_01090 | - | 3e-25 | 25.56% (313) | putative membrane transport protein |
| M. abscessus ATCC 19977 | MAB_1378c | - | 2e-24 | 26.21% (309) | magnesium/cobalt transporter CorA |
| M. marinum M | MMAR_1230 | corA_1 | 1e-125 | 65.96% (332) | magnesium and cobalt transport transmembrane protein |
| M. avium 104 | MAV_1379 | corA | 1e-24 | 28.10% (306) | magnesium and cobalt transport protein CorA |
| M. thermoresistible (build 8) | TH_3226 | - | 1e-127 | 66.96% (336) | PUTATIVE Mg2+ transporter protein, CorA family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1217 | - | 1e-136 | 72.62% (336) | Mg2+ transporter protein, CorA family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5126|M.gilvum_PYR-GCK ---------------------------------MTHVHGRIWRDGKTAD-
Mvan_1217|M.vanbaalenii_PYR-1 ---------------------------------MTQVRGRVWRDGKPID-
MSMEG_0111|M.smegmatis_MC2_155 ---------------------------------MAQVNGRVWRSGQPAE-
TH_3226|M.thermoresistible__bu ---------------------------------MRAVRGRIWRSGEPQD-
MMAR_1230|M.marinum_M ------------------------------MQVAPSVRGRVWRSGQLQD-
Mb1271c|M.bovis_AF2122/97 MFPGFDALPEVLRPVARP--QPPNAHPVAQPPAQALVDCGVYVCGQRLPG
Rv1239c|M.tuberculosis_H37Rv MFPGFDALPEVLRPVARP--QPPNAHPVAQPPAQALVDCGVYVCGQRLPG
MLBr_01090|M.leprae_Br4923 MFPGFDPLPEALRPVTKPRLYTPHVHPIFPPLTEPLVDCGVYVGGHRLPD
MAV_1379|M.avium_104 MFQGFDALPEVLRPIAHQ--PHPQPAPEAPPARATLVDCAVYDDGNRLPG
MAB_1378c|M.abscessus_ATCC_199 MARFPSVTPSSLRSPIRGREPETDAKRIPVPLARAIVDCGVYVDGVRLPG
* :: *
Mflv_5126|M.gilvum_PYR-GCK -----DFEFSAISEYLAT-EGTLLWCDIYDPDHATLKSLAEEIGLNEWAV
Mvan_1217|M.vanbaalenii_PYR-1 -----DFEFSAISDCLAS-DDTLVWCDIYSPDHAILKDLAQELNLNTWAV
MSMEG_0111|M.smegmatis_MC2_155 -----DFSFSAISDYLAD-DDTLVWADIYDPDHQTLLDLAAELGLNTWAV
TH_3226|M.thermoresistible__bu -----GFEFSALSDYLAE-PDTLVWVDIYDPDHEAFAELADEISLNLWAV
MMAR_1230|M.marinum_M -----EFDFDKIAEYLSE-ENTLVWADLCNPDHDTLSDLAEKLRLNHWAV
Mb1271c|M.bovis_AF2122/97 KYT-YAAALREVREIELTGQEAFVWIGLHEPDENQMQDVADVFGLHPLAV
Rv1239c|M.tuberculosis_H37Rv KYT-YAAALREVREIELTGQEAFVWIGLHEPDENQMQDVADVFGLHPLAV
MLBr_01090|M.leprae_Br4923 KYTTYTAALSRVREIELMGNEGFVWIGLHEPEASHMHNVADVFGLHPLAV
MAV_1379|M.avium_104 VFG-YAEALDKVREIESQGREGFVWVGLREPNQAEMQEVADVFGLHALAV
MAB_1378c|M.abscessus_ATCC_199 KYT-PNAALEKVRSLDR----GFVWVGLHEPDEHQMEAVAQPFGLHRLAV
: : . ::* .: .*: : :* : *: **
Mflv_5126|M.gilvum_PYR-GCK EDAIADAERTKAVVYKTHTFFTVYDVWVKDPAPEDNSESTLEIHRISGFV
Mvan_1217|M.vanbaalenii_PYR-1 EDALADAERTKAVVYRTHTFFTVYAVSVKEPPPSVFTESTLEKQRISAFV
MSMEG_0111|M.smegmatis_MC2_155 EDAVAPKERTKASVYKTHTFFTVYAIDILTSGGG--TGSLLVKHRISAFV
TH_3226|M.thermoresistible__bu EDAVAAAERTKATVYPTHTFFTVYAVTAGEPDRT---GKRLTTHRISAFV
MMAR_1230|M.marinum_M EDAVAAAERVKSTAYVTHTFFTVYDAGVVG-GLGEDTAPMLSMRRISAFV
Mb1271c|M.bovis_AF2122/97 EDAVHAHQRPKLERYDETLFLVLKTVNYVPHESVVLAREIVETGEIMIFV
Rv1239c|M.tuberculosis_H37Rv EDAVHAHQRPKLERYDETLFLVLKTVNYVPHESVVLAREIVKTGEIMIFV
MLBr_01090|M.leprae_Br4923 EDAVHAHQRPKLERYDDTLFLVLKTVNYVPHESVVLARQIVETGEVMIFV
MAV_1379|M.avium_104 EDAVCAHQRPKVERYDDTLFLVLKTVNYVPHESVVLAREIVETGEIMVFV
MAB_1378c|M.abscessus_ATCC_199 EDAVHAHNRPKLERYDDTLFLILKTVNYVEHDSISSAREIVETGEIMIFV
***: :* * * *: : : .: **
Mflv_5126|M.gilvum_PYR-GCK LPRGLITVRIS------PHVDMEKVSRRYD-DLGGQEHGVGSLVHALLDV
Mvan_1217|M.vanbaalenii_PYR-1 LPRGLITVRLS------NGFDIDEVSRRFD-ELGGQEYGVGSLVHGLLDV
MSMEG_0111|M.smegmatis_MC2_155 LPHGLITVRLPGLDGAAHEFDIHEVSRRFD-DLGGQRYGVGSLVHGLLDV
TH_3226|M.thermoresistible__bu LPRALITVRLP------PALDMSAVSQRFD-DLGGQRHGVGALLHALLDV
MMAR_1230|M.marinum_M LGQGLITVRLT------PDFDITEVTRRWD-EIGGQQYGVGALVHGLLDV
Mb1271c|M.bovis_AF2122/97 GKDFVVTVRHG------EHGGLSEVRKRMDADPEHLRLGPYAVMHAIADY
Rv1239c|M.tuberculosis_H37Rv GKDFVVTVRHG------EHGGLSEVRKRMDADPEHLRLGPYAVMHAIADY
MLBr_01090|M.leprae_Br4923 GKNFVVTVRHG------EHGELSEVRKRMDTDPEHLRLGSYAVMHAISDY
MAV_1379|M.avium_104 GRDFVVTVRHG------EHGGLSEVRKRMDGDPEQMRLGPFAVMHAIADH
MAB_1378c|M.abscessus_ATCC_199 GGDFVVTVRHG------DHSGLAKVRAQMDSDPDHMRLGPYAVMHAIADR
::*** : * : * : . * :::*.: *
Mflv_5126|M.gilvum_PYR-GCK VVDGHFTAVQSLDDGIESLEDDLFAERPLRGRLQRRTFQLRKDLVALRRV
Mvan_1217|M.vanbaalenii_PYR-1 VVDGHFDAVQVLDEGIEDLEDVLFDDTAPRKEFQHRTFQLRKDLVALRRV
MSMEG_0111|M.smegmatis_MC2_155 VVDGHFEAVEALDDAIEGLEDELFDDRGPNRGLQRRTFRLRKDLVELRRV
TH_3226|M.thermoresistible__bu VVDGHFAAIQVLDDAVEELEDDLFSASRPGKDLPQRTFQLRKDLVLLRRV
MMAR_1230|M.marinum_M VVDSHFAAVEALDDCIEAIEDELFENNSPRGSFQRRTFQIRRDLVNLRRI
Mb1271c|M.bovis_AF2122/97 VVDRYLEVTNLMETDIDSIEEVAFAPG--RKLDIEPIYLLKREVVELRRC
Rv1239c|M.tuberculosis_H37Rv VVDHYLEVTNLMETDIDSIEEVAFAPG--RKLDIEPIYLLKREVVELRRC
MLBr_01090|M.leprae_Br4923 VVDRYLAVTNLMEGDIDAIEEVAFAPG--RKLNVEPIYLLKREVIELRRC
MAV_1379|M.avium_104 VVDHYLEVSSLMLADIDSIEGLAFAPG--SKIDVEPIYLLKREVVELRRC
MAB_1378c|M.abscessus_ATCC_199 VVDSYMEVSDLVETDIEAMEQNVFSPR--SSTDIEHIYMLKREVVELRRA
*** :: . . : :: :* * . : :::::: ***
Mflv_5126|M.gilvum_PYR-GCK VLPMREVVTAIQHRRLDARNAVELDAVYADLYDHVLRASEWTESLRDMVT
Mvan_1217|M.vanbaalenii_PYR-1 VLPMREVVLAIQHRRLETKFAVELDPLYADLYDHVQRASEWTESLRDMVT
MSMEG_0111|M.smegmatis_MC2_155 VLPTREVVSTIQHRRLDSRTSPELDPLYADLYDHVLRASEWTESLRDMVT
TH_3226|M.thermoresistible__bu VLPMREVVSAIQRHRVERAAESALDPHYTDLYDHVLRAAEWTDSLRDMVT
MMAR_1230|M.marinum_M ALPMREVVNSLQHHRLHVEAARELDPLYADLYDHVLRVSEWTESLRDMIS
Mb1271c|M.bovis_AF2122/97 VNPLSTAFQRMQTESKD-LISKEVRRYLRDVADHQTEAADQIASYDDMLN
Rv1239c|M.tuberculosis_H37Rv VNPLSTAFQRMQTESKD-LISKEVRRYLRDVADHQTEAADQIASYDDMLN
MLBr_01090|M.leprae_Br4923 VAPLSAALQRMQTDNKD-LISKELRRYLRDVADHQTEAADQIASYDDMLN
MAV_1379|M.avium_104 VNPLSSAFHRIQTENKD-VISKEVRRYLRDVADHHSEAADQIASYDDMLN
MAB_1378c|M.abscessus_ATCC_199 ISPLTGALAKLTQDHND-LITKEVRRYLRDVLDHQTHAADKIGSYDELLT
* .. : . : *: ** ..:: * :::.
Mflv_5126|M.gilvum_PYR-GCK TVFETNLSLQDARLNIVMKKLTGWAAIIAVPTAITGFYGQNVDY-PGIDT
Mvan_1217|M.vanbaalenii_PYR-1 TVFETNLSLQDARLNTVMKKLTGWAAIVAVPTAITGFYGQNVDY-PGIDT
MSMEG_0111|M.smegmatis_MC2_155 TVFETHLSLQDARLNTVMKKLTGWAAIIAVPTAITGFYGQNVTY-PGVDT
TH_3226|M.thermoresistible__bu TVFETNLALQDAWLNSVMKKLTGWAAIIAIPTAVTGFYGQNVLF-PGIDT
MMAR_1230|M.marinum_M TIFETNLSLQDARLNAVMKKLTGWAAIIAVPTAITGFYGQNVPY-PGFGT
Mb1271c|M.bovis_AF2122/97 SLVQAALARVGMQQNMDMRKISAWAGIIAVPTMIAGIYGMNFHFMPELDS
Rv1239c|M.tuberculosis_H37Rv SLVQAALARVGMQQNMDMRKISAWAGIIAVPTMIAGIYGMNFHFMPELDS
MLBr_01090|M.leprae_Br4923 SLVQAALARVGMQQNNDMRKMAAWAGIVAMPTMVAAIYGMNFRFMPELNW
MAV_1379|M.avium_104 SLIQAALARVGMQQNNDMRKMAAWAGILAVPTMIAAIYGMNFHFMPELNW
MAB_1378c|M.abscessus_ATCC_199 SLVNAALGKVAMQQNTDMRKISAWVGIAAFPTMLAGIYGMNFEHMPELAE
::.:: *. * *:*::.*..* *.** ::.:** *. . * .
Mflv_5126|M.gilvum_PYR-GCK VGGFVTSTSIIVVLVIVLYWTFKARDWL
Mvan_1217|M.vanbaalenii_PYR-1 FSGFLASSAIIVVFVAVLYWAFKRRDWI
MSMEG_0111|M.smegmatis_MC2_155 VAGFVTSSALIAVLVGLLYVMFKRRDWL
TH_3226|M.thermoresistible__bu VGGFVTSTVIIVLLVAVLYVMFRRRNWL
MMAR_1230|M.marinum_M LAGFLASTSVIVVLMALLYVMFRRRDWL
Mb1271c|M.bovis_AF2122/97 RWGYPTVIGGMVLICLFLYHVFRNRNWL
Rv1239c|M.tuberculosis_H37Rv RWGYPTVIGGMVLICLFLYHVFRNRNWL
MLBr_01090|M.leprae_Br4923 TWSYPLVMAGMTIVCLVLYWQFRNRNWL
MAV_1379|M.avium_104 TWGYPAVMAGMAVVCLVLYFQFRNRNWL
MAB_1378c|M.abscessus_ATCC_199 PAAYPIVLLVMVLVCTLLYRNFRKNGWL
.: :.:. .** *: ..*: