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MGERGELVSDLHPSDDHDADPRLAPLLAWRQQLVDSGAVAPRSFKEAHLRLVLRSGRTDVEQIRAMLPGS VAEHAEEMARILAELTPAAPEPDPPPVPEPQPEPEPGPGKHRSPETDEPPVATTTEIPIPTTGFAPFQFS SQQVALHDITVQRTDAAVELSWPPYEAPEDEAAQDISVVMYRVVSSDDQAPYSPDPAHLVALTEEPKATD ERQQVSPVRHYQVWVNVGASEAAARKTQPVLYATAVLVRPVTGFEIREDAGWVIGQWTAPPGVTAVHVFR VPIDEVDRDEAQYRILTAGENLAGFVDTEPVRGQRYRYRARCAVNVDGVVRLSEAAEADVELAAALMPVT DLVVETAADGASCDLSWTPPAGGQVAIYRSQNGPSADAEAIELPQGALEQVGLTPELRVTQDLTEETGSD GRRRARLTGVTWPSEWSRAYFTPVTLMGERAMLGRTLSSVRTGTIRDIELAEYCNKQVLTFDWPDGAASV IVYLAPKGHDPRSGLNGRSFEISLEEYERYGGMHLTGQLPVGGCSLHLAPVAFAGGRRVVGAFSSIEYRG LLRLQYAVRIGRDPNGFPTTATIALRAEQNVPGSPGFVLVNNPQRLPLSVHDGHPVDVAPLDARGQLADH PSKELRWSALTTSGDGELWAANLSGLQGWIRLFVNIGSPAQLRVIALLDPPVETLRLTAATL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0044 | - | - | 100% (692) | hypothetical protein MSMEG_0044 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0309 | - | 6e-07 | 26.16% (172) | DNA polymerase III, subunit gamma/tau |
| M. marinum M | MMAR_5240 | dnaZX | 5e-06 | 26.44% (174) | DNA polymerase III (subunit gamma/tau) DnaZX |
| M. avium 104 | MAV_2273 | sucB | 3e-05 | 45.24% (42) | dihydrolipoamide acetyltransferase |
| M. thermoresistible (build 8) | TH_3554 | - | 2e-05 | 44.44% (45) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4315 | dnaZX | 2e-05 | 27.81% (169) | DNA polymerase III subunits gamma and tau |
| M. vanbaalenii PYR-1 | Mvan_3106 | - | 6e-06 | 26.98% (126) | hypothetical protein Mvan_3106 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_5240|M.marinum_M -----------------------MALYRKYRPATFAEVVGQEHVTEPLSI
MUL_4315|M.ulcerans_Agy99 -----------------------MALYRKYRPATFAEVVGQEHVTEPLSI
MAB_0309|M.abscessus_ATCC_1997 -------MAGARNRLWAPVPLLSVALYRKYRPATFAEVVGQEHVTGPLTT
TH_3554|M.thermoresistible__bu --------------------------------------------------
MAV_2273|M.avium_104 --------MAFSVQMPALGESVTEGTVTRWLKQEGDTVELDEPLVEVSTD
Mvan_3106|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0044|M.smegmatis_MC2_155 MGERGELVSDLHPSDDHDADPRLAPLLAWRQQLVDSGAVAPRSFKEAHLR
MMAR_5240|M.marinum_M ALEAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGTCESCQ
MUL_4315|M.ulcerans_Agy99 ALEAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGTCESCQ
MAB_0309|M.abscessus_ATCC_1997 ALDAGRINHAYLFSGPRGCGKTSSARILARSLNCVQGPTSTPCGTCESCV
TH_3554|M.thermoresistible__bu -------------------------------------VAADAAAPTAAAA
MAV_2273|M.avium_104 KVDTEIPSPAAGVLTKIIAQEDDTVEVGGELAVIGDAADDAAAGGGAQAP
Mvan_3106|M.vanbaalenii_PYR-1 ------------MATTTGYAGKRHAKWLAAAAAVPIMTFPAQAPAQAAAA
MSMEG_0044|M.smegmatis_MC2_155 LVLRSGRTDVEQIRAMLPGSVAEHAEEMARILAELTPAAPEPDPPPVPEP
MMAR_5240|M.marinum_M ALAPSAPGSIDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRVFIIDEA
MUL_4315|M.ulcerans_Agy99 ALAPSAPGSIDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRVFIIDEA
MAB_0309|M.abscessus_ATCC_1997 ALAPNGSGNVDVIELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIIDEA
TH_3554|M.thermoresistible__bu AVPADPEGSSTFRALAWSQEEGVDDVVPFTGDGAYPDGP-----------
MAV_2273|M.avium_104 SQPSQPQAPAQPEPQAQAQPEAPAQPQAPAQPAPQESGGGAATPVLMPEL
Mvan_3106|M.vanbaalenii_PYR-1 PISMLPEN-ARVLTLSLLPGGNDDDLRGEVCSGGRTCSSVPYPYLLRAEG
MSMEG_0044|M.smegmatis_MC2_155 QPEPEPGPGKHRSPETDEPPVATTTEIPIPTTGFAPFQFSSQQVALHDIT
.
MMAR_5240|M.marinum_M HMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKVLPTIRSRTHHYPFRLL
MUL_4315|M.ulcerans_Agy99 HMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKVLPTIRSRTHHYPFRLL
MAB_0309|M.abscessus_ATCC_1997 HMVTTAGFNALLKIVEEPPEHLIFVFATTEPEKVLPTIRSRTHHYPFRLL
TH_3554|M.thermoresistible__bu --FTEGGY----------------------------------TDGPFTGQ
MAV_2273|M.avium_104 GESVTEGTVTRWLKKVGDSVQVDDALVEVSTDKVDTEIPSPVAGVLISIT
Mvan_3106|M.vanbaalenii_PYR-1 VELLDQAIRQPLPTPEQP----------------------HQIVFGYSQG
MSMEG_0044|M.smegmatis_MC2_155 VQRTDAAVELSWPPYEAPEDEAAQDISVVMYRVVSSDDQAPYSPDPAHLV
.
MMAR_5240|M.marinum_M PPRTMRGLIGRICEQEGVVVDEAVYPLVTRAGGGSPRDTLSVLDQLVAGA
MUL_4315|M.ulcerans_Agy99 PRRTMRGLIGRICEQEGVVVDEAVYPLVTRAGGGSPRDTLSVLDQLVAGA
MAB_0309|M.abscessus_ATCC_1997 APKTMRTLVEGICAQENVSVDDPVYPLVIRAGAGSPRDTLSVLDQLLAGA
TH_3554|M.thermoresistible__bu ARPEVQWVPEQPVEESGAWSRLPVALFSVAG-------------------
MAV_2273|M.avium_104 AEEDSTVPVGGELARIGTGAQAPAPAAPQPPPAPKPEPK-----------
Mvan_3106|M.vanbaalenii_PYR-1 ARVAADWIAQHAGTEDAPSPEHLSFVLIGNPGRKYGG-------------
MSMEG_0044|M.smegmatis_MC2_155 ALTEEPKATDERQQVSPVRHYQVWVNVGASEAAARKTQPVLYATAVLVRP
.
MMAR_5240|M.marinum_M QSNHVTYQRALGLLGATDVALIDDAVDALGAGDAAALFGAVESVIDAGHD
MUL_4315|M.ulcerans_Agy99 QSNHVTYQRVLGLLGATDVALIDDAVDALGAGDAAALFGAVESVIDAGHD
MAB_0309|M.abscessus_ATCC_1997 DEERVTYQRALSLLGVTDIALIDDAVDALAAGDGAAVFGAIEGVMDAGHD
TH_3554|M.thermoresistible__bu --------------------------------------------------
MAV_2273|M.avium_104 --------------------------------------------------
Mvan_3106|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0044|M.smegmatis_MC2_155 VTG-----------------------------------------------
MMAR_5240|M.marinum_M PRRFATDLLERFRDLIVLQAVPDAVSRGVVDGPEDVLDRMREQAAHLGAA
MUL_4315|M.ulcerans_Agy99 PRRFATDLLERFRDLIVLQAVPDAVSHGVVDGPEDVLDRMREQAAHLGSA
MAB_0309|M.abscessus_ATCC_1997 PRRFGTDLLERFRDLIVLQAVPDAVERGVVDAPQDVLERMREQAERIGPA
TH_3554|M.thermoresistible__bu -----------VAVLLALGGVAYGLTSVSEDEPDPPVTEX--XXQVLFAA
MAV_2273|M.avium_104 -----PEPAPQPQAQPAPQPQPQPQAQPAPEPKAQPAQAQPAQAQPAAGG
Mvan_3106|M.vanbaalenii_PYR-1 -----------AHVGWGQTVPDSDYQILDVARQYDMAADMPDRFNLLALA
MSMEG_0044|M.smegmatis_MC2_155 ----FEIREDAGWVIGQWTAPPGVTAVHVFRVPIDEVDRDEAQYRILTAG
.
MMAR_5240|M.marinum_M TLTRYAEVVQAGLGEMRGATAPRLLL-EVVCARLLLPSASDAESALLQRI
MUL_4315|M.ulcerans_Agy99 TLTRYAEVVQAGLGEMRGATAPRLLL-EVVCARLLLPSASDAESALLQRI
MAB_0309|M.abscessus_ATCC_1997 TLTRYAEVLHAGLGEMRGATAPRLLL-EVVCARLLLPSATDAESAVLQRV
TH_3554|M.thermoresistible__bu GVVAVLVALIAAIVTLRDGDTP-------------APASTTEP-------
MAV_2273|M.avium_104 EGTPYVTPLVRKLAAENNIDLSSITG-TGVGGRIRKQDVLAAAEQKQRQQ
Mvan_3106|M.vanbaalenii_PYR-1 NVLAGFMFIHADYEEVDLYDPRNYVWKEGNTTYVFIPTENLPLLEPLRWL
MSMEG_0044|M.smegmatis_MC2_155 ENLAGFVDTEPVRGQRYRYRARCAVNVDGVVRLSEAAEADVELAAALMPV
MMAR_5240|M.marinum_M ERIETRLAMSIPAGAGATSAP----------APEAPAAPEAPAAPRATTS
MUL_4315|M.ulcerans_Agy99 ERIETRLAMSIPAGAGATSAP----------APEAPAA------PRATTS
MAB_0309|M.abscessus_ATCC_1997 ERIEKRLDMSVPEADGASAAPRFVRKSQAAAAPAAETAASPAPAPQPPRP
TH_3554|M.thermoresistible__bu ----TEPTTTEPAGTVVTEAP-----------------------PPAEPA
MAV_2273|M.avium_104 QAAAQPSAAPAPAAAEARKPAAP---------------------TPAPAL
Mvan_3106|M.vanbaalenii_PYR-1 GLTGIADALNGPLKAIVEDAYDR-------------------SYLPAEPG
MSMEG_0044|M.smegmatis_MC2_155 TDLVVETAADGASCDLSWTPPAG----------GQVAIYRSQNGPSADAE
. . .
MMAR_5240|M.marinum_M ARAEAKEMVRQSMRRPAP-PEPKSAPER----------------------
MUL_4315|M.ulcerans_Agy99 ARAGAKEMVRQSMRRPAP-PEPKSVPEP----------------------
MAB_0309|M.abscessus_ATCC_1997 APEPPAPIPGPAPEPPAPRPEPEPAPEP----------------------
TH_3554|M.thermoresistible__bu APQPPRTVYETVPQTQAP---PPPAEAP----------------------
MAV_2273|M.avium_104 AHLRGTTQKASRIRQITAAKTRESLLAT----------------------
Mvan_3106|M.vanbaalenii_PYR-1 LPSEPEPEPEPEPEPEEPQTDPEPEGET----------------------
MSMEG_0044|M.smegmatis_MC2_155 AIELPQGALEQVGLTPELRVTQDLTEETGSDGRRRARLTGVTWPSEWSRA
MMAR_5240|M.marinum_M --PPAPEPRPAPEPRRAPEPRPAPESRPAPVPEPVSA-----PGELNAAA
MUL_4315|M.ulcerans_Agy99 --PPAPEPRPAPEPRRAPEPR------PAPVPEPVSA-----PGELNAAA
MAB_0309|M.abscessus_ATCC_1997 --EPAPEPTPIPEPP-APEPAPEPEPEPAPVPEPEPAREPRQPGALDTTA
TH_3554|M.thermoresistible__bu --PPAQEPPPAEEPPPAEEPPPATEEPPP-------------------TT
MAV_2273|M.avium_104 --AQLTQTHEVDMTRLVGLRARAKAAFAEREGVNLTFLPFIARAVIDALK
Mvan_3106|M.vanbaalenii_PYR-1 --APLTSVQSLTIDEDDQGSVPEEATSDQQ------------------AA
MSMEG_0044|M.smegmatis_MC2_155 YFTPVTLMGERAMLGRTLSSVRTGTIRDIELAEYCNKQVLTFDWPDGAAS
MMAR_5240|M.marinum_M VRSMWPTVREKVRQRSRTTEVMLAAATVRALEDNTLVLTHDSAPLARRLS
MUL_4315|M.ulcerans_Agy99 VRSMWPTVREKVRQRSRTTEVMLAAATVRALEDNTLVLTHDSAPLARRLS
MAB_0309|M.abscessus_ATCC_1997 VRNAWAEIRAKVRDRSRTTEVMLSGATVRAIDGNTLVLSHDSPPLAKRIT
TH_3554|M.thermoresistible__bu TRPRWLPTLPRPTLPTLPTIPGLPAPPAPPAEAP----------------
MAV_2273|M.avium_104 IHPNINASYNEETKEITYYDAEHLGFAVDTEQGLLSPVVHNAGDLSLAGL
Mvan_3106|M.vanbaalenii_PYR-1 EDQQAAEETQEPEEAQEPEEAQEPEEAAEEAEEAAEPEAEEAEAPEAEEA
MSMEG_0044|M.smegmatis_MC2_155 VIVYLAPKGHDPRSGLNGRSFEISLEEYERYGGMHLTGQLPVGGCSLHLA
MMAR_5240|M.marinum_M EQRNADVIAEALRDALGVNWRVRCEVGAAEPAATPT--PAKAAA------
MUL_4315|M.ulcerans_Agy99 EQRNADVIAEALRDALGVNWRVRCEVGAAEPAATPT--PAKAAA------
MAB_0309|M.abscessus_ATCC_1997 ESRNAEVIREALRDALGVNWEIRCDVGSAEAAAPAASRPAKAAPRVVTRP
TH_3554|M.thermoresistible__bu --------------------------------------------------
MAV_2273|M.avium_104 ARAIADIAARARSGNLKPDELSGGTFTITNIGSQGALFDTPILVPPQAAM
Mvan_3106|M.vanbaalenii_PYR-1 EEAQEDPEDSSGTDDTPAQDSSSGDSSGGDE-------------------
MSMEG_0044|M.smegmatis_MC2_155 PVAFAGGRRVVGAFSSIEYRGLLRLQYAVRIGRDPNGFPTTATIALRAEQ
MMAR_5240|M.marinum_M --PAADPVAVDSARRE------EEESLLAEAGRSDPSEPRRDPEEVALEL
MUL_4315|M.ulcerans_Agy99 --PAADPVAVDSARRE------EEESLLAEAGRSDPSEPRRDPEEVALEL
MAB_0309|M.abscessus_ATCC_1997 SRPTPDPEPVPEPEPEPPSPEDEEEQMLAEAGQSEAG-PRRDPEEVALEL
TH_3554|M.thermoresistible__bu --------------------------------------------------
MAV_2273|M.avium_104 LGTGAIVKRPRVIVDEFGNESIGVRSVCYLPLTYDHRLIDGADAGRFLTT
Mvan_3106|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0044|M.smegmatis_MC2_155 NVPGSPGFVLVNNPQRLPLSVHDGHPVDVAPLDARGQLADHPSKELRWSA
MMAR_5240|M.marinum_M LRNELGARRIDNA-------------------------------------
MUL_4315|M.ulcerans_Agy99 LRNELGARRIDNA-------------------------------------
MAB_0309|M.abscessus_ATCC_1997 LQNELGARKIDPN-------------------------------------
TH_3554|M.thermoresistible__bu --------------------------------------------------
MAV_2273|M.avium_104 IKHRLEEGAFEADLGL----------------------------------
Mvan_3106|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0044|M.smegmatis_MC2_155 LTTSGDGELWAANLSGLQGWIRLFVNIGSPAQLRVIALLDPPVETLRLTA
MMAR_5240|M.marinum_M ---
MUL_4315|M.ulcerans_Agy99 ---
MAB_0309|M.abscessus_ATCC_1997 ---
TH_3554|M.thermoresistible__bu ---
MAV_2273|M.avium_104 ---
Mvan_3106|M.vanbaalenii_PYR-1 ---
MSMEG_0044|M.smegmatis_MC2_155 ATL