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TLSLSNHLAEDSVYLALRRDVFDGLQKSPKSLPPKWFYDAVGSELFDQITRLPEYYPTRAEAQILRARSA DIAAASSADTLVELGSGTSEKTRLLLNALRDRGLLQRFVPFDVDESVLSAAASAIQSEYAGIEINAVCGD FEEHLAEIPTGGRRLFVFLGSTIGNLTPGPRAEFLAGLAAVMRPGDSLLLGTDLVKDTDRLIRAYDDAAG VTARFNRNVLAVVNRELDADFNVDAYQHIARWNSVEERIEMWLRAEGRQRVRVRALGLTVDFAAGEEMLT EVSCKFRPEGVSAELDAAGLRRIQWWTDEAGDFGLSLATK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5212 | - | - | 100% (321) | s-adenosyl-L-methionine-dependentmethyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3727c | - | 1e-153 | 81.93% (321) | hypothetical protein Mb3727c |
| M. gilvum PYR-GCK | Mflv_1318 | - | 1e-138 | 75.62% (320) | hypothetical protein Mflv_1318 |
| M. tuberculosis H37Rv | Rv3701c | - | 1e-153 | 81.93% (321) | hypothetical protein Rv3701c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0372 | - | 1e-121 | 67.40% (319) | hypothetical protein MAB_0372 |
| M. avium 104 | MAV_0402 | - | 1e-152 | 82.55% (321) | hypothetical protein MAV_0402 |
| M. smegmatis MC2 155 | MSMEG_6247 | - | 1e-138 | 76.64% (321) | hypothetical protein MSMEG_6247 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4285 | - | 1e-180 | 99.07% (321) | S-adenosyl-L-methionine-dependentmethyltransferase |
| M. vanbaalenii PYR-1 | Mvan_5483 | - | 1e-138 | 74.14% (321) | hypothetical protein Mvan_5483 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1318|M.gilvum_PYR-GCK -MV----FSLENLLAADAAEEALRRDVAHGLTQQPKSLPPKWFYDATGSD
Mvan_5483|M.vanbaalenii_PYR-1 -MT----FSLENYLAADAADEALRRDVRHGLTQHPKTLPPKWFYDSVGSD
MMAR_5212|M.marinum_M -MT----LSLSNHLAEDSVYLALRRDVFDGLQKSPKSLPPKWFYDAVGSE
MUL_4285|M.ulcerans_Agy99 -MT----LSLSNHLAEDSVYLALRRDVFDGLQKSPKSLPPKWFYDAVGSE
Mb3727c|M.bovis_AF2122/97 -MR----VSVANHLGEDAGHLALRRDVYSGLQKTPKSLPPKWFYDTVGSE
Rv3701c|M.tuberculosis_H37Rv -MR----VSVANHLGEDAGHLALRRDVYSGLQKTPKSLPPKWFYDTVGSE
MAV_0402|M.avium_104 MMT----LSLSNHLAADSAHHALRRDVLDGLRRTPKSLPPKWFYDSVGSD
MSMEG_6247|M.smegmatis_MC2_155 -MT----LSLANYLAADSAAEALRRDVRAGLTAAPKSLPPKWFYDAVGSD
MAB_0372|M.abscessus_ATCC_1997 -MTPLPPMTLENHLASGAAAAALRRDVRQGLTAKAKSLPPKWFYDEAGSD
* .:: * *. .: ****** ** .*:******** .**:
Mflv_1318|M.gilvum_PYR-GCK LFDQITRLPEYYPTRAEAQILRSRASEIAAASGADTLVELGSGTSEKTRM
Mvan_5483|M.vanbaalenii_PYR-1 LFDQITRLPEYYPTRAEAQILHARAAEIAAASGADTLVELGSGTSEKTRA
MMAR_5212|M.marinum_M LFDQITRLPEYYPTRAEAQILRARSADIAAASSADTLVELGSGTSEKTRL
MUL_4285|M.ulcerans_Agy99 LFDRITRLPEYYPTRAEAQILRARSADIAAASSADTLVELGSGTSEKTRL
Mb3727c|M.bovis_AF2122/97 LFDQITRLPEYYPTRAEAEILRARSAEVASACRADTLVELGSGTSEKTRM
Rv3701c|M.tuberculosis_H37Rv LFDQITRLPEYYPTRAEAEILRARSAEVASACRADTLVELGSGTSEKTRM
MAV_0402|M.avium_104 LFDQITRLPEYYPTRAEAEILRAQAPGIASASEADTLVELGSGTSEKTRV
MSMEG_6247|M.smegmatis_MC2_155 LFDQITRLPEYYPTRTEAQILRTRSAEIIAAAGADTLVELGSGTSEKTRM
MAB_0372|M.abscessus_ATCC_1997 LFDEITRLPEYYPTRTEAGLLRAHAADIAAACGADTLVELGSGTSEKTRM
***.***********:** :*::::. : :*. ****************
Mflv_1318|M.gilvum_PYR-GCK LLDALRDRGSLRRFIPFDVDSSVLTAAGAAIETEYPGIEITAVCGDFEEH
Mvan_5483|M.vanbaalenii_PYR-1 LLDAMRDRGTLRRFIPFDVDASVLKDAGASIEAEYPGVQIEAVCGDFEEH
MMAR_5212|M.marinum_M LLNALRDRGLLQRFVPFDVDESVLSAAASAIQSEYAGIEINAVCGDFEEH
MUL_4285|M.ulcerans_Agy99 LLNALRDRGLLQRFVPFDVDESVLSAAVSAIQSEYAGIEINAVCGDFEEH
Mb3727c|M.bovis_AF2122/97 LLDALRHRGSLRRFVPFDVDASVLSATATAIQREYSGVEINAVCGDFEEH
Rv3701c|M.tuberculosis_H37Rv LLDALRHRGSLRRFVPFDVDASVLSATATAIQREYSGVEINAVCGDFEEH
MAV_0402|M.avium_104 LLDALRERGALRRYVPFDVDAGILSASAAAIQREYAGIEIQAVCGDFEEH
MSMEG_6247|M.smegmatis_MC2_155 LLDAMRDAELLRRFIPFDVDAGVLRSAGAAIGAEYPGIEIDAVCGDFEEH
MAB_0372|M.abscessus_ATCC_1997 LLDALDPN----TFIPFDVDSGVLRAAGDALVAEYPGMSVRAVCGDFEKD
**:*: ::***** .:* : :: **.*:.: *******:.
Mflv_1318|M.gilvum_PYR-GCK LGKIPGDGRRLVAFLGSTIGNFTPGPRAEFLASVAQMMQPGDTLLLGTDL
Mvan_5483|M.vanbaalenii_PYR-1 LGKIPAVGRRLVAFLGSTIGNLTPGPRAEFLASVAELMQPGDTLLLGTDL
MMAR_5212|M.marinum_M LAEIPTGGRRLFVFLGSTIGNLTPGPRAEFLAGLAAVMRPGDSLLLGTDL
MUL_4285|M.ulcerans_Agy99 LAEIPTGGRRLFVFLGSTIGNLTPGPRAEFLAGLAAVMRPGDSLLLGTDL
Mb3727c|M.bovis_AF2122/97 LTEIPRGGRRLFVFLGSTIGNLTPGPRAQFLTALAGVMRPGDSLLLGTDL
Rv3701c|M.tuberculosis_H37Rv LTEIPRGGRRLFVFLGSTIGNLTPGPRAQFLTALAGVMRPGDSLLLGTDL
MAV_0402|M.avium_104 LTEIPEGGRRLFVFLGSTIGNLTPGPRAQFLAALSAQMRPGDSLLLGTDL
MSMEG_6247|M.smegmatis_MC2_155 LGKIPHVGRRLVVFLGSTIGNLTPAPRAEFLSTLADTLQPGDSLLLGTDL
MAB_0372|M.abscessus_ATCC_1997 LARIPREGRRLVAFLGSTIGNLTAEPRARFLADVAATLQSGEMLLLGTDL
* .** ****..********:*. ***.**: :: ::.*: *******
Mflv_1318|M.gilvum_PYR-GCK VKDTERLVRAYDDGAGVTARFNRNVLAVVNRKLGADFDIDAFEHVAVWNG
Mvan_5483|M.vanbaalenii_PYR-1 VKDTGRLLRAYDDSAGVTARFNRNVLAVINRELGADFGVEAFEHVARWNA
MMAR_5212|M.marinum_M VKDTDRLIRAYDDAAGVTARFNRNVLAVVNRELDADFNVDAYQHIARWNS
MUL_4285|M.ulcerans_Agy99 VKDTDRLIRAYDDAAGVTARFNRNVLAVVNRELDADFNVDAYQHIARWNS
Mb3727c|M.bovis_AF2122/97 VKDAARLVRAYDDPGGVTAQFNRNVLAVINRELEADFDVDAFQHVARWNS
Rv3701c|M.tuberculosis_H37Rv VKDAARLVRAYDDPGGVTAQFNRNVLAVINRELEADFDVDAFQHVARWNS
MAV_0402|M.avium_104 VKDTERLVRAYDDAAGVTAAFNRNVLAVINRELDADFDVDAFEHVARWNV
MSMEG_6247|M.smegmatis_MC2_155 VKDTGRLVRAYDDAAGVTAAFNRNVLAVVNRELSADFDLDAFEHVAKWNS
MAB_0372|M.abscessus_ATCC_1997 VKDAERLVRAYDDSAGVTAAFNRNVLAVINRELDADFDLDAFDHVARWNG
***: **:***** .**** ********:**:* ***.::*::*:* **
Mflv_1318|M.gilvum_PYR-GCK DEQRIEMWLRSTRAQRVRIDALDLDVDFADGEQMLTEVSSKFRPSGVEEE
Mvan_5483|M.vanbaalenii_PYR-1 AEERIEMWLRSTRAQRVHIAALDLAVDFADGEQLLTEVSCKFRPSGVDQE
MMAR_5212|M.marinum_M VEERIEMWLRAEGRQRVRVRALGLTVDFAAGEEMLTEVSCKFRPEGVSAE
MUL_4285|M.ulcerans_Agy99 VEERIEMWLRAEGRQRVRVRALGLTLDFAAGEEMLTEVSCKFRPEGVSAE
Mb3727c|M.bovis_AF2122/97 AEERIEMWLRADGRQRVRVGALDLTVDFDAGEEMLTEVSCKFRPQAVGAE
Rv3701c|M.tuberculosis_H37Rv AEERIEMWLRADGRQRVRVGALDLTVDFDAGEEMLTEVSCKFRPQAVGAE
MAV_0402|M.avium_104 DEERIEMWLRATGRQRVRVGALGLTVDFRAGEEMLTEVSCKFRPERVSAE
MSMEG_6247|M.smegmatis_MC2_155 DEERIEMWLRARTAQHVRVAALDLEVDFAAGEEMLTEVSCKFRPENVVAE
MAB_0372|M.abscessus_ATCC_1997 DEERMEMWLRSVRDQRITIEALDLSVDFEAGEMMLTEVSCKFRREGVARE
*:*:*****: *:: : **.* :** ** :*****.*** . * *
Mflv_1318|M.gilvum_PYR-GCK LAAAGLRRTHWWTDEAGDFGLSLATL-
Mvan_5483|M.vanbaalenii_PYR-1 LASAGLRRTHWWTDDAGDFGLSLAVK-
MMAR_5212|M.marinum_M LDAAGLRRIQWWTDEAGDFGLSLATK-
MUL_4285|M.ulcerans_Agy99 LDAAGLRRIQWWTDEAGDFGLSLATK-
Mb3727c|M.bovis_AF2122/97 LAAAGLHRIRWWTDEAGDFGLSLAAK-
Rv3701c|M.tuberculosis_H37Rv LAAAGLHRIRWWTDEAGDFGLSLAAK-
MAV_0402|M.avium_104 LAAAGLRRTRWWTDGAEDFGLSLAVK-
MSMEG_6247|M.smegmatis_MC2_155 LAEAGLRQTHWWTDPAGDFGLSLAVR-
MAB_0372|M.abscessus_ATCC_1997 LAAAGLRQTHWWTDDADDFGLSLAVKE
* ***:: :**** * *******.