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SPHPRPVAQIWCSFCAKPDTEIDMLVAGAGVQICNECVATAAAIMDTYRDRPREVRLPMWEAMDDQQMLS HIPRIAVMAGQVEADLRAWVAELRRRGVTWSRVGEALGITRQSAWERFSVQR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3428 | - | - | 100% (123) | hypothetical protein MMAR_3428 |
| M. marinum M | MMAR_3805 | clpX | 9e-05 | 42.86% (35) | ATP-dependent Clp protease ATP-binding subunit ClpX |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2682 | - | 1e-06 | 45.61% (57) | hypothetical protein Mb2682 |
| M. gilvum PYR-GCK | Mflv_2591 | clpX | 7e-05 | 42.86% (35) | ATP-dependent protease ATP-binding subunit |
| M. tuberculosis H37Rv | Rv2664 | - | 1e-06 | 45.61% (57) | hypothetical protein Rv2664 |
| M. leprae Br4923 | MLBr_01477 | clpX | 5e-06 | 45.71% (35) | ATP-dependent protease ATP-binding subunit ClpX |
| M. abscessus ATCC 19977 | MAB_1583 | clpX | 7e-05 | 42.86% (35) | ATP-dependent protease ATP-binding subunit ClpX |
| M. avium 104 | MAV_1716 | clpX | 7e-05 | 42.86% (35) | ATP-dependent protease ATP-binding subunit |
| M. smegmatis MC2 155 | MSMEG_4671 | clpX | 9e-05 | 42.86% (35) | ATP-dependent protease ATP-binding subunit |
| M. thermoresistible (build 8) | TH_0353 | clpX | 3e-05 | 39.13% (46) | PROBABLE ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT |
| M. ulcerans Agy99 | MUL_2703 | - | 2e-65 | 93.50% (123) | hypothetical protein MUL_2703 |
| M. vanbaalenii PYR-1 | Mvan_4036 | clpX | 8e-05 | 42.86% (35) | ATP-dependent protease ATP-binding subunit |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01477|M.leprae_Br4923 -MARIGDSGDLLKCSFCGKSQTQVKKLIAGPGVYICDECIDLCNEIIEEE
MAV_1716|M.avium_104 -MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEE
MAB_1583|M.abscessus_ATCC_1997 -MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEE
MSMEG_4671|M.smegmatis_MC2_155 -MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEE
Mflv_2591|M.gilvum_PYR-GCK -MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEE
TH_0353|M.thermoresistible__bu -MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEE
Mvan_4036|M.vanbaalenii_PYR-1 -MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEE
MMAR_3428|M.marinum_M -MSPHPRPVAQIWCSFCAKPDTEIDMLVAGAGVQICNECVATAAAIMDTY
MUL_2703|M.ulcerans_Agy99 MLSAHPTPVAQIWCSFCAKPDTEIDMLVAGAGVQICNECVATAAAIMDTY
Mb2682|M.bovis_AF2122/97 -----------------MKHKTDID-------------------EWLDTI
Rv2664|M.tuberculosis_H37Rv -----------------MKHKTDID-------------------EWLDTI
* ..::. ::
MLBr_01477|M.leprae_Br4923 LADADDVQLDELPKPVEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAG
MAV_1716|M.avium_104 LADADDVKLDELPKPIEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAG
MAB_1583|M.abscessus_ATCC_1997 LADADDVKLDELPKPAEIRDFLENYVIGQDTAKKTLAVAVYNHYKRIQAG
MSMEG_4671|M.smegmatis_MC2_155 LADADDVKLDELPKPAEIREFLEGYVIGQDSAKRTLAVAVYNHYKRIQAG
Mflv_2591|M.gilvum_PYR-GCK LADADDVKLDELPKPAEIRDFLEGYVIGQDTAKRTLAVAVYNHYKRIQAG
TH_0353|M.thermoresistible__bu LADADEVKLDELPKPAEIHEFLESYVIGQESAKRTLAVAVYNHYKRIQAG
Mvan_4036|M.vanbaalenii_PYR-1 LADADDVKLDELPKPAEIREFLEGYVIGQDTAKRTLAVAVYNHYKRIQAG
MMAR_3428|M.marinum_M RDRPREVRLPMWEAMDDQ-----------------------QMLSHIPRI
MUL_2703|M.ulcerans_Agy99 RDRPHEVRLPMWESMDDQ-----------------------QMLSYIPRI
Mb2682|M.bovis_AF2122/97 EPNP--------ADAHDA-----------------------SHLRRIIAA
Rv2664|M.tuberculosis_H37Rv EPNP--------ADAHDA-----------------------SHLRRIIAA
. : . *
MLBr_01477|M.leprae_Br4923 EKGRDSKREPVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATA
MAV_1716|M.avium_104 EKGRDSRHEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATA
MAB_1583|M.abscessus_ATCC_1997 DKARDARGETVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATA
MSMEG_4671|M.smegmatis_MC2_155 EKSRDSRSEPVELTKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATA
Mflv_2591|M.gilvum_PYR-GCK EKARDSRAEPVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATA
TH_0353|M.thermoresistible__bu EKSRDSRSEPVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATA
Mvan_4036|M.vanbaalenii_PYR-1 EKARDSRSEPVELAKSNILMLGPTGCGKTYLAQTLAKMLNVPFAIADATA
MMAR_3428|M.marinum_M AVMAGQVEADLRAWVAELRRRGVTWS-----------RVGEALGITRQSA
MUL_2703|M.ulcerans_Agy99 AVVAGQVEADLRAWVAELRRRGVTWS-----------RVGGALGVTRQSA
Mb2682|M.bovis_AF2122/97 KEAVQTAESELRAAVNAARAAGDTWA-----------AIGVALGITRQAA
Rv2664|M.tuberculosis_H37Rv KEAVQTAESELRAAVNAARAAGDTWA-----------AIGVALGITRQAA
:. * * . :. .:.:: :*
MLBr_01477|M.leprae_Br4923 LTEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPS
MAV_1716|M.avium_104 LTEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPS
MAB_1583|M.abscessus_ATCC_1997 LTEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPS
MSMEG_4671|M.smegmatis_MC2_155 LTEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPS
Mflv_2591|M.gilvum_PYR-GCK LTEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPS
TH_0353|M.thermoresistible__bu LTEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPS
Mvan_4036|M.vanbaalenii_PYR-1 LTEAGYVGEDVENILLKLIQAADYDVKRAETGIIYIDEVDKIARKSENPS
MMAR_3428|M.marinum_M WERFSVQR------------------------------------------
MUL_2703|M.ulcerans_Agy99 WERFSVQR------------------------------------------
Mb2682|M.bovis_AF2122/97 FQRFGPHSTASP--------------------------------------
Rv2664|M.tuberculosis_H37Rv FQRFGPHSTASP--------------------------------------
. .
MLBr_01477|M.leprae_Br4923 ITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIV
MAV_1716|M.avium_104 ITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIV
MAB_1583|M.abscessus_ATCC_1997 ITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIV
MSMEG_4671|M.smegmatis_MC2_155 ITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIV
Mflv_2591|M.gilvum_PYR-GCK ITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIV
TH_0353|M.thermoresistible__bu ITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIV
Mvan_4036|M.vanbaalenii_PYR-1 ITRDVSGEGVQQALLKILEGTQASVPPQGGRKHPHQEFIQIDTTNVLFIV
MMAR_3428|M.marinum_M --------------------------------------------------
MUL_2703|M.ulcerans_Agy99 --------------------------------------------------
Mb2682|M.bovis_AF2122/97 --------------------------------------------------
Rv2664|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01477|M.leprae_Br4923 AGAFAGLDKIIYERIGKRGLGFGAEVRSKAEIDTTDHFADVMPEDLIKFG
MAV_1716|M.avium_104 AGAFAGLEKIIYERVGKRGLGFGAEVRSKAEIDTTDHFAEVMPEDLIKFG
MAB_1583|M.abscessus_ATCC_1997 AGAFAGLEKIVSDRVGKRGLGFGAEVKSKADIDTTDHFAEVMPEDLIKFG
MSMEG_4671|M.smegmatis_MC2_155 AGAFAGLEKIVSDRVGKRGLGFGAEVRSKAEIDTQDHFAEVMPEDLIKFG
Mflv_2591|M.gilvum_PYR-GCK AGAFAGLEKIVSDRVGKRGLGFGAEVHSKAEIDTQDHFAEVMPEDLIKFG
TH_0353|M.thermoresistible__bu AGAFAGLEKIVQDRVGKRGLGFGAEVHSKSEIDTTDHFAEVMPEDLIKYG
Mvan_4036|M.vanbaalenii_PYR-1 AGAFAGLERIVSDRVGKRGLGFGAEVKSKAEIDTQDHFAEVMPEDLIKFG
MMAR_3428|M.marinum_M --------------------------------------------------
MUL_2703|M.ulcerans_Agy99 --------------------------------------------------
Mb2682|M.bovis_AF2122/97 --------------------------------------------------
Rv2664|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01477|M.leprae_Br4923 LIPEFIGRLPVIASVINLDMESLVKILSEPKNALVKQYTWLFEMDGVELE
MAV_1716|M.avium_104 LIPEFIGRLPVVASVTNLDRESLVKILSEPKNALVKQYTRLFEMDGVELE
MAB_1583|M.abscessus_ATCC_1997 LIPEFIGRLPIVASVTNLDRESLIKILSEPKNALVKQYTRLFEMDGVELE
MSMEG_4671|M.smegmatis_MC2_155 LIPEFIGRLPVVASVTNLDKASLVKILSEPKNALVKQYVRLFEMDGVELE
Mflv_2591|M.gilvum_PYR-GCK LIPEFIGRLPVVASVTNLDKESLVKILSEPKNALVKQYTRLFEMDGVELE
TH_0353|M.thermoresistible__bu LIPEFIGRLPVVASVTNLDKNSLVQILSKPKNALVKQYTKLFEMDGVELE
Mvan_4036|M.vanbaalenii_PYR-1 LIPEFIGRLPVVASVTNLDKESLVQILSQPKNALVKQYTRLFEMDGVELE
MMAR_3428|M.marinum_M --------------------------------------------------
MUL_2703|M.ulcerans_Agy99 --------------------------------------------------
Mb2682|M.bovis_AF2122/97 --------------------------------------------------
Rv2664|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01477|M.leprae_Br4923 FTNDALEAVADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVT
MAV_1716|M.avium_104 FTDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVT
MAB_1583|M.abscessus_ATCC_1997 FSQDALEAIADQAIHRGTGARGLRAIMEEVLQPVMYDIPSRDDVAKVVVT
MSMEG_4671|M.smegmatis_MC2_155 FTEEALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVT
Mflv_2591|M.gilvum_PYR-GCK FAEDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVT
TH_0353|M.thermoresistible__bu FTDDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVT
Mvan_4036|M.vanbaalenii_PYR-1 FAEDALEAIADQAIHRGTGARGLRAIMEEVLLPVMYDIPSRDDVAKVVVT
MMAR_3428|M.marinum_M --------------------------------------------------
MUL_2703|M.ulcerans_Agy99 --------------------------------------------------
Mb2682|M.bovis_AF2122/97 --------------------------------------------------
Rv2664|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01477|M.leprae_Br4923 KETVQDNVLPTIVPRKPSRTERRDKSA
MAV_1716|M.avium_104 KETVQDNVLPTIVPRKPSRTERRDKSA
MAB_1583|M.abscessus_ATCC_1997 GETVIDNVLPTIVPRKPSRTERRDKSA
MSMEG_4671|M.smegmatis_MC2_155 KETVQDNVLPTIVPRKPSRSERRDKSA
Mflv_2591|M.gilvum_PYR-GCK KETVDDNVLPTIVPRKPSRSERRDKTA
TH_0353|M.thermoresistible__bu KETVLDNVLPTIVPRKPSRAERRDKTA
Mvan_4036|M.vanbaalenii_PYR-1 KETVLDNVLPTIVPRKPSRTERRDKSA
MMAR_3428|M.marinum_M ---------------------------
MUL_2703|M.ulcerans_Agy99 ---------------------------
Mb2682|M.bovis_AF2122/97 ---------------------------
Rv2664|M.tuberculosis_H37Rv ---------------------------