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SSGAKKYGILVAVDGSAQSDAAVAWAAREAGLHRTPITLMHGVAPVVVGWPVGQLYAEMPDWQRDEANSV MERARKVLSEALGDSESPDVRTEVVYSNVVAALIEASTQASMVVVGSQGMGALGRMLLGSVCSALLHHAH CPVAVVHSDSGAAPDPGAAVVVGIDGSPAAEAATAMAFEEASRRGVDLVALHAWSDVGVFPILGMDWRER ESQGEEILAERLAGWQEQYPDVHVKRSLVCDKPAHWLLEEAQHAQLVIVGNRGRGGFPGMLLGSVSSTVA HSAKVPVIVVRPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2995 | - | - | 100% (294) | hypothetical protein MMAR_2995 |
| M. marinum M | MMAR_3477 | - | 3e-81 | 51.01% (298) | hypothetical protein MMAR_3477 |
| M. marinum M | MMAR_2993 | - | 5e-80 | 50.17% (293) | hypothetical protein MMAR_2993 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2051c | - | 1e-123 | 71.43% (294) | hypothetical protein Mb2051c |
| M. gilvum PYR-GCK | Mflv_4992 | - | 1e-95 | 57.58% (297) | UspA domain-containing protein |
| M. tuberculosis H37Rv | Rv2026c | - | 1e-123 | 71.43% (294) | hypothetical protein Rv2026c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2489 | - | 8e-44 | 37.12% (299) | hypothetical protein MAB_2489 |
| M. avium 104 | MAV_2506 | - | 1e-115 | 69.66% (290) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_3940 | - | 1e-96 | 58.95% (285) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_2494 | - | 6e-70 | 46.91% (307) | PUTATIVE putative conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_2236 | - | 1e-166 | 98.98% (294) | hypothetical protein MUL_2236 |
| M. vanbaalenii PYR-1 | Mvan_1386 | - | 4e-93 | 55.82% (292) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4992|M.gilvum_PYR-GCK MSDPS--TDLGILVGVDGSPESHAAVRWAAQEAVLRRRPVTLMHVVSPIV
Mvan_1386|M.vanbaalenii_PYR-1 MSESS--SEFGILVGVDGSPEAHSAVRWAVQEAALRHRPITLMHVVAPVV
MSMEG_3940|M.smegmatis_MC2_155 MSHNGNGAGYGMVVAVDGSAESDAAVRWAAREATLRKIPVTVMHVVEPMI
MMAR_2995|M.marinum_M --MSSGAKKYGILVAVDGSAQSDAAVAWAAREAGLHRTPITLMHGVAPVV
MUL_2236|M.ulcerans_Agy99 --MSSGAKKYGILVAVDGSAQSDAAVPWAAREAGLHRTPITLMHGVAPVV
Mb2051c|M.bovis_AF2122/97 --MSAATAKYGILVGVDGSAQSNAAVAWAAREAVMRQLPITLLHIVAPVV
Rv2026c|M.tuberculosis_H37Rv --MSAATAKYGILVGVDGSAQSNAAVAWAAREAVMRQLPITLLHIVAPVV
MAV_2506|M.avium_104 --MSD-PKHRGILVCVDGSAASDAAVAWAAREAAMRGLPITVIHAVAPVV
TH_2494|M.thermoresistible__bu --VSSTAAYEGIVVGVDGSAASADAVRWAARSAALRNLQLTLVHVMTATS
MAB_2489|M.abscessus_ATCC_1997 --MTTSTPNSHILVGVDGSTSALHALTWAGAEAQRRNLPLTLVHVIDHSS
::* ****. : *: ** .* : :*::* :
Mflv_4992|M.gilvum_PYR-GCK VT----WPIDTVVANFYEWQEDNAARVLKQSQETLAAAVSDT--------
Mvan_1386|M.vanbaalenii_PYR-1 VT----WPIEAVVTSFYEWQEDNAKSVIEQSQETVAAATAGA--------
MSMEG_3940|M.smegmatis_MC2_155 VN----WPVPPVQGSVTEWQEANARNVIKHAHDTFVAVEESA--------
MMAR_2995|M.marinum_M VG----WPVGQLYAEMPDWQRDEANSVMERARKVLSEALGDS--------
MUL_2236|M.ulcerans_Agy99 VG----WPVGQLYAEMPDWQRDEANSVMERARKVLSEALGDS--------
Mb2051c|M.bovis_AF2122/97 VG----WPVGQLYANMTEWQKDNAQQVIEQAREALTNSLGES--------
Rv2026c|M.tuberculosis_H37Rv VG----WPVGQLYANMTEWQKDNAQQVIEQAREALTNSLGES--------
MAV_2506|M.avium_104 VG----WPVGQLYADMPAWQQDGAQQVIDQARKIVIANQGGG--------
TH_2494|M.thermoresistible__bu IGAPLVWPAGPIPDSLIQWQEDEARQILADSAEIAENAFQEARAAGPGPA
MAB_2489|M.abscessus_ATCC_1997 LGQG--YNLG-ASASFFQHLETDGAEFLSQAKDHVYALHPNV--------
: : .. . . .: : .
Mflv_4992|M.gilvum_PYR-GCK --TAPTVEVEVRHDGIVPEFTEASQHADLLVLGSRGLGPVGGAVLGSVSR
Mvan_1386|M.vanbaalenii_PYR-1 --PPPEVRVEVRHGGAVTEFADASAHADLMVVGSRGLGPVGGAVLGSVSR
MSMEG_3940|M.smegmatis_MC2_155 --PDG-IRHEIRYAGIVAELVDVSKNATMMVVGSRGLGAFGGALLGSVSS
MMAR_2995|M.marinum_M --ESPDVRTEVVYSNVVAALIEASTQASMVVVGSQGMGALGRMLLGSVCS
MUL_2236|M.ulcerans_Agy99 --ESPDVRTEVVYSNVVAALIEASTQASMVVVGSQGMGALGRMLLGSVCS
Mb2051c|M.bovis_AF2122/97 --KPPQVHTELVFSNVVPTLIDASQQAWLMVVGSQGMGALGRLLLGSIST
Rv2026c|M.tuberculosis_H37Rv --KPPQVHTELVFSNVVPTLIDASQQAWLMVVGSQGMGALGRLLLGSIST
MAV_2506|M.avium_104 --TPPEMRTEIIYSAVTPTLIDASRDAWMIVAGSQGLGALGRLLLGSVTA
TH_2494|M.thermoresistible__bu GDDAVRVVTGVVRAAPVPTLVDASKQAKLVAVGSRGQGPLRRVLLGSVSS
MAB_2489|M.abscessus_ATCC_1997 -----EVSTVKATGRPVPVLVELSRNALMTVLGSSGLGGFTGMMAGSVSV
: .. : : * .* : . ** * * . : **:
Mflv_4992|M.gilvum_PYR-GCK ALLHHAQCPVVIAKEGVVPRDA-GALPVLLGIDGSPASENATTFAFDEAS
Mvan_1386|M.vanbaalenii_PYR-1 ALLHHAKCPVVVTREGVVGKPH-DTLPVLLGIDGSPASENATAFAFDEAS
MSMEG_3940|M.smegmatis_MC2_155 GVIHHAHCPVAVIHGDQIRRPD-PRSPVLVGIDGSPASEDATAFAFDEAS
MMAR_2995|M.marinum_M ALLHHAHCPVAVVHSDSGAAPD-PGAAVVVGIDGSPAAEAATAMAFEEAS
MUL_2236|M.ulcerans_Agy99 ALLHHAHCPVAVVHSDSGAAPD-PGAAVVVGIDGSPAAEAATAMAFEEAS
Mb2051c|M.bovis_AF2122/97 ALLHHARCPVAIIHSGNGATPD-SDAPVLVGIDGSPASEAATALAFDEAS
Rv2026c|M.tuberculosis_H37Rv ALLHHARCPVAIIHSGNGATPD-SDAPVLVGIDGSPASEAATALAFDEAS
MAV_2506|M.avium_104 ALLAHAHCPVAVVHTDDHAARA-ADAPVLVGTDGSPASEAAIALAFDEAS
TH_2494|M.thermoresistible__bu GLVHHAHCPVAVIREGTPHTPDFAKRPVLVGIDGSESAQRATAVAFEEAS
MAB_2489|M.abscessus_ATCC_1997 SLTAKGHSPVVVVRESPVPGGG----PVVVGIDDSESSDGAAAWAFEEAA
.: :.:.**.: : . .*::* *.* ::: * : **:**:
Mflv_4992|M.gilvum_PYR-GCK RRGADLVALHAWSDVA------VFPILGMDWHQYEQQGHEILAERLAGWQ
Mvan_1386|M.vanbaalenii_PYR-1 RRGVELVVLHAWSDVA------VFPILGMDWHQYEQQGHEVLGERLAGWQ
MSMEG_3940|M.smegmatis_MC2_155 RRRVDLIALHAWSDVG------VFSALGMDWHEYEDQGRELLGERLAGWR
MMAR_2995|M.marinum_M RRGVDLVALHAWSDVG------VFPILGMDWRERESQGEEILAERLAGWQ
MUL_2236|M.ulcerans_Agy99 RRGVDLVALHAWSDVG------VFPILGMDWRERESQGEEILAERLASWQ
Mb2051c|M.bovis_AF2122/97 RRRVDLVALHAWTDLG------MFPVLGMDWREREKREAEVLAERLAGWQ
Rv2026c|M.tuberculosis_H37Rv RRRVDLVALHAWTDLG------MFPVLGMDWREREKREAEVLAERLAGWQ
MAV_2506|M.avium_104 RRGVGVVALHAWSDVG------VFPILGMDWRDSEAKGEELLAERLAGWQ
TH_2494|M.thermoresistible__bu FRGVDLIALHAWSDAD------IADIPTLELSAVQQSAERVLSERLAGFR
MAB_2489|M.abscessus_ATCC_1997 MRETELVAVHVWNNIPPGYVYAYTAWSAMDSAGEQQRQEQLLAERLAGWQ
* . ::.:*.*.: :: : .:*.****.::
Mflv_4992|M.gilvum_PYR-GCK ERYPDVHIRRRIVCDTPARWLIDESRHSQLVVVGSRGRGGIAGLLLGSVS
Mvan_1386|M.vanbaalenii_PYR-1 ERYPDVAIRRRIVCDKPARWLIDESRQAQLVVVGSRGRGGISSMLLGSVS
MSMEG_3940|M.smegmatis_MC2_155 ERYPDVRVTRQIVCDQPARWLIDGSRHAQLVVVGSHGRAGFAGMLLGSVG
MMAR_2995|M.marinum_M EQYPDVHVKRSLVCDKPAHWLLEEAQHAQLVIVGNRGRGGFPGMLLGSVS
MUL_2236|M.ulcerans_Agy99 QQYPDVHVKRSLVCDKPAHWLLEEAQHAQLVIVGNRGRGGFPGMLLGSVS
Mb2051c|M.bovis_AF2122/97 EQYPDVRVHRSLVCDKPARWLLEHSEQAQLVVVGSHGRGGFSGMLLGSVS
Rv2026c|M.tuberculosis_H37Rv EQYPDVRVHRSLVCDKPARWLLEHSEQAQLVVVGSHGRGGFSGMLLGSVS
MAV_2506|M.avium_104 EQYPDVHVKRLVVCDKPSRWLVAEAERAQLVVVGSHGRGGFPGMLLGSVS
TH_2494|M.thermoresistible__bu ERYPDVSVHRRIVGSEPARHLVEASEDAQLVVVGSRGRGGFTGMLLGSVS
MAB_2489|M.abscessus_ATCC_1997 EKYPDVPVRRVVAVGHPADVLLSQAAGAQLIVTGSRGRGDIAGFFLGSTS
::**** : * :. . *: *: : :**::.*.:**..:..::***..
Mflv_4992|M.gilvum_PYR-GCK TTVAESALAPVAVVRG-
Mvan_1386|M.vanbaalenii_PYR-1 TAVAESALAPVAVVRG-
MSMEG_3940|M.smegmatis_MC2_155 SKVARAAYSPVIVVR--
MMAR_2995|M.marinum_M STVAHSAKVPVIVVRPA
MUL_2236|M.ulcerans_Agy99 STVAHSAKVPVIVVRPA
Mb2051c|M.bovis_AF2122/97 SAVAHSVRIPVIVVRPS
Rv2026c|M.tuberculosis_H37Rv SAVAHSVRIPVIVVRPS
MAV_2506|M.avium_104 SHVAQSATAPVIVVRGR
TH_2494|M.thermoresistible__bu RAVVNAVTTPVIVAR--
MAB_2489|M.abscessus_ATCC_1997 HALIHKASCPVLVAPRT
: . . ** *.