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MNFSVMPPEINSVLMFAGAGSEPMLLAARGWSELSAELQSAAAGFASLTSGLTGQFWQGAAAQAMTGVAQ AYAAHLSATAAQAGQVSAQANGVAAVFDAARAAIVHPLQVAANRTQLVSLVVSNLFGQNAPAIAAVEANY EEMWAQDVSAMSGYYTAASAAVAQLTPWELTSEGIVIPLPDHIGVLNFTPGNIGSLNLGIGNVGDLNLGS GNTGAGNLGLGNFGELNLGSGNGNSGNGDSTTPLLASFNLGSGNLGDANLGSGNLGMLNLGSGNKGDTNF GFGNIGDLNLGSGNIGSHNFGSGNSGSANLGSGNTGNSNFGLGNTGSTNLGSGNTGSANFGSGNLGDANV GWGNLGSHNFGFGNNGSNNIGIGLTGDNQIGINFGALNSGHGNIGLFNSGNDNVGFFNSGDKNIGIANSG LGVGPLSTEFFTSGEFNSGVGSSGTLNTGWGNSGSTNTGYFNAGHTNTGLFNSGDTSTGLFNSGDTNTGL FNSGDTNTGFFNAGTANFGSFNGGSTNTGDWNSGSINTGYANSGGTNTGILNAGNLNTGAFSPFDQPVVN SGFSNDFDGPFGKGGVNQSGAFNQGVGNSGFDSGDNIKGGTVSSSGFENHGNFGSGFLNAGSFSSGFRNT GPEGINPGFMSGFVNSSGTFISGFFNAGTFTPGLLETFNSGFGNLGNQVSGLFNAQNVKSGPIH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1297 | - | - | 100% (694) | PPE family protein |
| M. marinum M | MMAR_5331 | - | 0.0 | 52.46% (751) | PPE family protein |
| M. marinum M | MMAR_4554 | - | 0.0 | 51.42% (704) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1575c | PPE21 | 0.0 | 55.49% (710) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 7e-22 | 27.31% (509) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1548c | PPE21 | 0.0 | 55.49% (710) | PPE family protein |
| M. leprae Br4923 | MLBr_01182 | - | 6e-26 | 39.75% (161) | PPE-family protein |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-21 | 27.10% (465) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_2913 | - | 1e-45 | 39.31% (318) | PPE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 9e-24 | 27.53% (494) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3113 | - | 3e-22 | 37.34% (158) | PUTATIVE PPE protein |
| M. ulcerans Agy99 | MUL_0902 | - | 1e-169 | 50.53% (663) | PPE family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 9e-21 | 28.29% (463) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1575c|M.bovis_AF2122/97 --------------------------------------------------
Rv1548c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1297|M.marinum_M --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------------MMFLAPPG
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MAV_2913|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1575c|M.bovis_AF2122/97 --------------------------------------------------
Rv1548c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1297|M.marinum_M --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---------------------------------------MVTFGGGATPT
Mvan_1264|M.vanbaalenii_PYR-1 GPGPISAAIQLTSTGSEATEP----------------WYVVSFGGSGAPT
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MAV_2913|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1575c|M.bovis_AF2122/97 --------------------------------------------------
Rv1548c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1297|M.marinum_M --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK PTSLGAA-------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 PNNLAAS-------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MAV_2913|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1575c|M.bovis_AF2122/97 --------------------------------------------------
Rv1548c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1297|M.marinum_M --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MAV_2913|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1575c|M.bovis_AF2122/97 -----------------------------------------MNFSVLPPE
Rv1548c|M.tuberculosis_H37Rv -----------------------------------------MNFSVLPPE
MMAR_1297|M.marinum_M -----------------------------------------MNFSVMPPE
MUL_0902|M.ulcerans_Agy99 -----------------------------------------MNFPMLPPE
Mflv_5091|M.gilvum_PYR-GCK --------------------AVDLSGTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 --------------------LVDLSGTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MAV_2913|M.avium_104 ----------------------------------------MSIYAGLPPE
MLBr_01182|M.leprae_Br4923 ----------------------------------------MFDFAALSPE
TH_3113|M.thermoresistible__bu --------------------------------------------MALPPE
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------MSIIDFILNLFRDPVE
Mb1575c|M.bovis_AF2122/97 IN-----SALMFAGAGPGPMLAAASAWTGLAGDLGSAAASFSAVTSQLAT
Rv1548c|M.tuberculosis_H37Rv IN-----SALMFAGAGPGPMLAAASAWTGLAGDLGSAAASFSAVTSQLAT
MMAR_1297|M.marinum_M IN-----SVLMFAGAGSEPMLLAARGWSELSAELQSAAAGFASLTSGLTG
MUL_0902|M.ulcerans_Agy99 IN-----SARMFAGAGSGPMLSAAMAWDGLAVELGSAAESFGSVTSGLVG
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
MAV_2913|M.avium_104 VN-----SARMYSGPGSESMLAAAAAWNALSAELRSAATDYESAIATLTG
MLBr_01182|M.leprae_Br4923 TN-----STRMYLGPGSSPILTAAAAWVVLAKELTAAAQGLQSAVEALLT
TH_3113|M.thermoresistible__bu VH-----STLLRTGPGPGALSAAADAWRMLSDEYRAAAVELAAVVSQTCA
MAB_4284c|M.abscessus_ATCC_199 AASYVADPEAALANAGLS-AVSAAQVGAVMPVVAESVASNYGYQSQWVNT
. * . .
Mb1575c|M.bovis_AF2122/97 GSWQGPASAAMTGAAASYARW-LTTAAAQAEQAAGQAQAAVSAFEAALAA
Rv1548c|M.tuberculosis_H37Rv GSWQGPASAAMTGVAASYARW-LTTAAAQAEQAAGQAQAAVSAFEAALAA
MMAR_1297|M.marinum_M QFWQGAAAQAMTGVAQAYAAH-LSATAAQAGQVSAQANGVAAVFDAARAA
MUL_0902|M.ulcerans_Agy99 SSWQGAAATAMSAAAAPYVSW-LNAAAVRAGEAALQAKEVVSAFEAARAA
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNG-GNGGVGVVGATGAVG--APGVAGATGAT
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNG-GNGGVGIAGATGAVG--APGVAGATGAT
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAG-GAGGVGADGTSAHVDGGTGGTGGTGGGT
MAV_2913|M.avium_104 EGWFGPSAAKMSAAVTPYLEW-LHSTATQAEQAGAQANAAAAAYQAAFAA
MLBr_01182|M.leprae_Br4923 -TFEGESAAALAERVTPYEKW-LTQNAASAELTATQLTVAANAYETAFTM
TH_3113|M.thermoresistible__bu TAWEGVGADAYAAAHGPYLFW-LTDTAAAAAAAGAQLEAAAAAHASALAA
MAB_4284c|M.abscessus_ATCC_199 GNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNP
. :
Mb1575c|M.bovis_AF2122/97 TVHPGAVSANRGRLRSLVASNLLGQNAPAIAAVEAV--------------
Rv1548c|M.tuberculosis_H37Rv TVHPGAVSANRGRLRSLVASNLLGQNAPAIAAVEAV--------------
MMAR_1297|M.marinum_M IVHPLQVAANRTQLVSLVVSNLFGQNAPAIAAVEAN--------------
MUL_0902|M.ulcerans_Agy99 MIHPLAVAANRNALVQLVLTNLFGQNAPAIAAAEGS--------------
Mflv_5091|M.gilvum_PYR-GCK GVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 GVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNV
MAV_2913|M.avium_104 TVPPAVVAANRTQLANLVAGNIFGQNAGLIAANEAQ--------------
MLBr_01182|M.leprae_Br4923 TVPPLMVFVNRAQACLLIMSNIFGQNSTAIAEKEAE--------------
TH_3113|M.thermoresistible__bu MPTMAELTANRTTHAALVATNFFGVNTIPIAVNEAD--------------
MAB_4284c|M.abscessus_ATCC_199 IASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRD--------------
.
Mb1575c|M.bovis_AF2122/97 -YEQMWAADVAAMLGYHGEASAVALSLTPFTPSPSAAA--------TPGG
Rv1548c|M.tuberculosis_H37Rv -YEQMWAADVAAMLGYHGEASAVALSLTPFTPSPSAAA--------TPGG
MMAR_1297|M.marinum_M -YEEMWAQDVSAMSGYYTAASAAVAQLTPWELTS---------------E
MUL_0902|M.ulcerans_Agy99 -YEQMWAADVAAMLGYHGGASAAASGLASWQQALQG--------------
Mflv_5091|M.gilvum_PYR-GCK AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG-----
Mvan_1264|M.vanbaalenii_PYR-1 AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG-----
MSMEG_0868|M.smegmatis_MC2_155 TVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDG
MAV_2913|M.avium_104 -YGDMWAQDAAAMTGYASASNAATQQLTPFTPPRPD--------------
MLBr_01182|M.leprae_Br4923 -YTEMWIQDAAAMTSYQASVLEAVGATKAFTAPPLGVN------------
TH_3113|M.thermoresistible__bu -YARMWIQAATTMATYEAVASAAVSATPRTVAPPPILG------------
MAB_4284c|M.abscessus_ATCC_199 --TTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVRDSN----------II
Mb1575c|M.bovis_AF2122/97 AVIIAGFPFLDLGNVTIGGFNLASGNLG---------------LGNLGSF
Rv1548c|M.tuberculosis_H37Rv AVIIAGFPFLDLGNVTIGGFNLASGNLG---------------LGNLGSF
MMAR_1297|M.marinum_M GIVIPLPDHIGVLNFTPG--NIGSLNLG---------------IGNVGDL
MUL_0902|M.ulcerans_Agy99 ---LAGPAASVILGLSIG--NTGVGNLS---------------IGNIGVF
Mflv_5091|M.gilvum_PYR-GCK --AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGL
Mvan_1264|M.vanbaalenii_PYR-1 --VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTA
MSMEG_0868|M.smegmatis_MC2_155 HAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGH
MAV_2913|M.avium_104 --TTANGIAAQANTVAQAANDAGSGDPS---------------GGLLAWL
MLBr_01182|M.leprae_Br4923 EVGLAQEVVEEVVEEVVEEVVEAEQAIS------------------QAAL
TH_3113|M.thermoresistible__bu -AGTGESATAAITGAHVTAELRAAESRT-----------------LLDEI
MAB_4284c|M.abscessus_ATCC_199 NADHGSNVGVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTNI
Mb1575c|M.bovis_AF2122/97 NPGSANTGSVNLG-------------------------NANIGDLNLGSG
Rv1548c|M.tuberculosis_H37Rv NPGSANTGSVNLG-------------------------NANIGDLNLGSG
MMAR_1297|M.marinum_M NLGSGNTGAGNLG-------------------------LGNFGELNLGSG
MUL_0902|M.ulcerans_Agy99 NLGGGNAGNLNLG-------------------------GGNTGNANLGSG
Mflv_5091|M.gilvum_PYR-GCK GETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGA
Mvan_1264|M.vanbaalenii_PYR-1 GETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGV
MSMEG_0868|M.smegmatis_MC2_155 STGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEI
MAV_2913|M.avium_104 GLAPNTNGPGQPG---------------------------LAGLMNFLDG
MLBr_01182|M.leprae_Br4923 DQAVNEGMEATVVP-------------------------QVDQQVNVDVA
TH_3113|M.thermoresistible__bu NELIDRLFAPLFPP-------------------------GFADALPDGLL
MAB_4284c|M.abscessus_ATCC_199 NDSFNTDRSTNIGS-------------------------GNTTNTEIGSH
.
Mb1575c|M.bovis_AF2122/97 N----------------------------------IGSYN----------
Rv1548c|M.tuberculosis_H37Rv N----------------------------------IGSYN----------
MMAR_1297|M.marinum_M NG----------------------NSGNGDSTTPLLASFN----------
MUL_0902|M.ulcerans_Agy99 N----------------------------------NGFFN----------
Mflv_5091|M.gilvum_PYR-GCK G----------STGAVGG-------VGGKG----IQGGQG----------
Mvan_1264|M.vanbaalenii_PYR-1 G----------ATGGAGG-------VGGKG----IQGGQG----------
MSMEG_0868|M.smegmatis_MC2_155 YSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGT
MAV_2913|M.avium_104 S-------------------------------------------------
MLBr_01182|M.leprae_Br4923 TP------------------------------------------------
TH_3113|M.thermoresistible__bu G-------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 N----------------------------------QANIG----------
Mb1575c|M.bovis_AF2122/97 ---LGGGNTGDLNPGSGNTGTLNWGS------------------GNIGSY
Rv1548c|M.tuberculosis_H37Rv ---LGGGNTGDLNPDSGNTGTLNWGS------------------GNIGSY
MMAR_1297|M.marinum_M ---LGSGNLGDANLGSGNLGMLNLGS------------------GNKGDT
MUL_0902|M.ulcerans_Agy99 ---LGSGNTGNTNFGNGNRGNLNWGS------------------GNLGNA
Mflv_5091|M.gilvum_PYR-GCK ---LQGGKGGDGGAGGKGGDADSMGS------------------AGATGG
Mvan_1264|M.vanbaalenii_PYR-1 ---LQGGQGGDGGTGGTGGDATSMGE------------------AGATGG
MSMEG_0868|M.smegmatis_MC2_155 AKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGA
MAV_2913|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---TSTSAGGSAAVGGNAGLAGNAGLAG----------------NAGLAG
Mb1575c|M.bovis_AF2122/97 NLGGGNLGSYNLGSGNTGDTNFGGGNTGNLNVGGGNTGNS----------
Rv1548c|M.tuberculosis_H37Rv NLGGGNLGSYNLGSGNTGDTNFGGGNTGNLNVGGGNTGNS----------
MMAR_1297|M.marinum_M NFGFGNIGDLNLGSGNIGSHNFGSGNSGSANLGSGNTGNS----------
MUL_0902|M.ulcerans_Agy99 NVGFGNF----LGQG-----NFGFGN---------RVGDA----------
Mflv_5091|M.gilvum_PYR-GCK KGGNGGNGGRGGLFG---------------KGGNAGNGAD----------
Mvan_1264|M.vanbaalenii_PYR-1 KGGNGGNGGRGSLFG---------------RGGNAGNGGN----------
MSMEG_0868|M.smegmatis_MC2_155 VGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNG
MAV_2913|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGNAG---------------LAGNAGLAGN----------
Mb1575c|M.bovis_AF2122/97 -----------------NFGFGNTGNVNFGNGNTGD--------------
Rv1548c|M.tuberculosis_H37Rv -----------------NFGFGNTGNVNFGNGNTGD--------------
MMAR_1297|M.marinum_M -----------------NFGLGNTGSTNLGSGNTGS--------------
MUL_0902|M.ulcerans_Agy99 -----------------NLGSGNLGNANFGNGNLGD--------------
Mflv_5091|M.gilvum_PYR-GCK ------------GGTGGAGGAGGTGG-TGGAGGTGG--------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------GGTGGNGGNGGTGG-TGGNGGTGG--------------
MSMEG_0868|M.smegmatis_MC2_155 PAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTG
MAV_2913|M.avium_104 --------------------DGNVLG------------------------
MLBr_01182|M.leprae_Br4923 -----------------QTAVPDSSS------------------------
TH_3113|M.thermoresistible__bu -----------------TLLAPLLPG------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------AGLAGNAGLAGNAGLAGNAGLAGN--------------
.
Mb1575c|M.bovis_AF2122/97 --TNFGSGNLGSGNIGFGNKGSHNIG-FGNSGNNNIGFGLTG-----DNQ
Rv1548c|M.tuberculosis_H37Rv --TNFGSGNLGSGNIGFGNKGSHNIG-FGNSGNNNIGFGLTG-----DNQ
MMAR_1297|M.marinum_M --ANFGSGNLGDANVGWGNLGSHNFG-FGNNGSNNIGIGLTG-----DNQ
MUL_0902|M.ulcerans_Agy99 --TNLGSGNNGFSNVGFGNLGSNNLG-FGNNGDNNIGFGLTG-----NNQ
Mflv_5091|M.gilvum_PYR-GCK ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGK
Mvan_1264|M.vanbaalenii_PYR-1 ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGK
MSMEG_0868|M.smegmatis_MC2_155 QTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGR
MAV_2913|M.avium_104 --SFLNNASVANLSNAFTTSGLLNPTSFVDAAVNLNSINSLN--------
MLBr_01182|M.leprae_Br4923 ---AAAPQLWGGFAQHLSPINDTLSMINNHAGMANAGLSLVN--------
TH_3113|M.thermoresistible__bu ---ATGDGPPMATIMSFLLMGLSNPAYLFPVLVYLLFTGVVH--------
MAB_4284c|M.abscessus_ATCC_199 -AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG----NAGL
. .
Mb1575c|M.bovis_AF2122/97 IG--FGALNSGSGNLGFGNSGNGNIGFFNSGN------------NNIGMG
Rv1548c|M.tuberculosis_H37Rv IG--FGALNSGSGNLGFGNSGNGNIGFFNSGN------------NNIGMG
MMAR_1297|M.marinum_M IGINFGALNSGHGNIGLFNSGNDNVGFFNSGD------------KNIGIA
MUL_0902|M.ulcerans_Agy99 VGINFAGLNGGIGNIDLGNSGDNNVGFFNSGS------------NNVGFF
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNG
MAV_2913|M.avium_104 ---AVDSTTSGLGVLAAGLGGTANLASAAAPG-------------AAAAA
MLBr_01182|M.leprae_Br4923 ------GMGSAMKSLAPTTTKAAESAFKAMGS-------------AVQST
TH_3113|M.thermoresistible__bu ---TTVAVSGMLAQLVPLMPALLPVAVAALGG-----------LAGVWAG
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAGNAAVAGNAAVAGNAAVAG----------NAAVGGVL
. . . .
Mb1575c|M.bovis_AF2122/97 NSGNGVGALSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTG--------
Rv1548c|M.tuberculosis_H37Rv NSGNGVGALSVEFGSSAERSSGFGNSGELSTGIGNSGQLSTG--------
MMAR_1297|M.marinum_M NSGLGVGPLSTEFFTSGEFNSGVGSSGTLNTGWGNSGSTNTG--------
MUL_0902|M.ulcerans_Agy99 NSG--------------DRNFGFANSGDTNTGFWNAGRVNTG--------
Mflv_5091|M.gilvum_PYR-GCK GAG-----------DGTGGTGGTGG----TGGQGGQGGQGG---------
Mvan_1264|M.vanbaalenii_PYR-1 GAG-----------DGLGGTGGTGG----TGGFGGQGGQGG---------
MSMEG_0868|M.smegmatis_MC2_155 GAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVI
MAV_2913|M.avium_104 EVG----------------QASLVGALSVPPTWGATGAAITP--------
MLBr_01182|M.leprae_Br4923 GRG----------------LLGSSSGGHVTAQLGRAASIGSLR-------
TH_3113|M.thermoresistible__bu LSG----------------LAGLAGLTAVPAADGGASAAPVP--------
MAB_4284c|M.abscessus_ATCC_199 NTG-----------VSGAIGGSSHVGGAINESLGGSGSVGGSTAVG----
* . .
Mb1575c|M.bovis_AF2122/97 ------WFNSATTSTGWFNSGTTNTG-----------------------W
Rv1548c|M.tuberculosis_H37Rv ------WFNSATTSTGWFNSGTTNTG-----------------------W
MMAR_1297|M.marinum_M ------YFNAGHTNTGLFNSGDTSTG-----------------------L
MUL_0902|M.ulcerans_Agy99 ------FGNGGNFNLGFGNGGAANVG-----------------------V
Mflv_5091|M.gilvum_PYR-GCK --------TGGTGGQGG-LGGGGGTG-----------------------G
Mvan_1264|M.vanbaalenii_PYR-1 --------TGGTGGQGG-LGGVGGTG-----------------------G
MSMEG_0868|M.smegmatis_MC2_155 GSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDG
MAV_2913|M.avium_104 ------------------LAATTQVG------------------------
MLBr_01182|M.leprae_Br4923 ---------VPQTWTTASQPVTAATR------------------------
TH_3113|M.thermoresistible__bu --------AGGPSLPSGSSAPPAPTG------------------------
MAB_4284c|M.abscessus_ATCC_199 --------GGAHTGVGGGVSTGVGVG-----------------------S
.
Mb1575c|M.bovis_AF2122/97 FNSGTTNTGIGNSGGNLVTGSMG------LFNSGHTNTGSFNAGSMNTGD
Rv1548c|M.tuberculosis_H37Rv FNSGTTNTGIGNSGGNLVTGSMG------LFNSGHTNTGSFNAGSMNTGD
MMAR_1297|M.marinum_M FNSGDTNTGLFNSG----DTNTG------FFNAGTANFGSFNGGSTNTGD
MUL_0902|M.ulcerans_Agy99 GNGGGGNLGFGNSG----TENTG------SFNSGGDNGR--NGG--NTGS
Mflv_5091|M.gilvum_PYR-GCK QGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGG
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGG
MSMEG_0868|M.smegmatis_MC2_155 HGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGG
MAV_2913|M.avium_104 ------------LG------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu ----------------------------------------SAAPTTGTAP
MAB_4284c|M.abscessus_ATCC_199 HVGGGISESLGGSGSVGGSTAVG--------GGAHTGVGGGVSTGVGVGS
Mb1575c|M.bovis_AF2122/97 FNSGNVNTGYFNSGNINTGFFNSGD-------------------------
Rv1548c|M.tuberculosis_H37Rv FNSGNVNTGYFNSGNINTGFFNSGD-------------------------
MMAR_1297|M.marinum_M WNSGSINTGYANSGGTNTGILNAGN-------------------------
MUL_0902|M.ulcerans_Agy99 FNSGYVNTGFFNSGSTNTGLFNAGS-------------------------
Mflv_5091|M.gilvum_PYR-GCK SGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGK
Mvan_1264|M.vanbaalenii_PYR-1 VGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGT
MSMEG_0868|M.smegmatis_MC2_155 DGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGST
MAV_2913|M.avium_104 --------AYHGFGSATPMVMEEAG-------------------------
MLBr_01182|M.leprae_Br4923 ----ALSPARVAVATESESAPLLGG-------------------------
TH_3113|M.thermoresistible__bu GGAGSPPPAGHSVPPAPHSAPPVGTS------------------------
MAB_4284c|M.abscessus_ATCC_199 HVGGGISESLGGSGSVGGSTAVGGG-------------------------
Mb1575c|M.bovis_AF2122/97 ---LNTGLFNSVNQPVQNSGWLHT--------GTNNSGYANAGTFNSGFD
Rv1548c|M.tuberculosis_H37Rv ---LNTGLFNSVNQPVQNSGWLHT--------GTNNSGYANAGTFNSGFD
MMAR_1297|M.marinum_M ---LNTGAFSPFDQPVVNSGFSNDFDGPFGKGGVNQSGAFNQGVGNSGFD
MUL_0902|M.ulcerans_Agy99 ---VNTGIGSPDTQPGSISGFGNT--------GAGVSGFNNSGDATSGFM
Mflv_5091|M.gilvum_PYR-GCK AGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGAT
Mvan_1264|M.vanbaalenii_PYR-1 AGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSA
MSMEG_0868|M.smegmatis_MC2_155 LGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDG
MAV_2913|M.avium_104 -------------------------------------AVGMPGVPLAGLP
MLBr_01182|M.leprae_Br4923 -------------------------------------GLPMAPMVPGGGS
TH_3113|M.thermoresistible__bu ------------------------------GPPYLIAAQPAPGVARRSAG
MAB_4284c|M.abscessus_ATCC_199 ---AHTGVGGGVN-------------------TGVGVGSHVGGGISESLG
. .
Mb1575c|M.bovis_AF2122/97 NNARDEHAEFVTG--------------------NSGLANVGNYNAGIINV
Rv1548c|M.tuberculosis_H37Rv NNARDEHAEFVTG--------------------NSGLANVGNYNAGIINV
MMAR_1297|M.marinum_M --SGDNIKGGTVS--------------------SSGFENHGNFGSGFLNA
MUL_0902|M.ulcerans_Agy99 N-----VATTFGF--------------------ASGINNVGDYQVGLFNT
Mflv_5091|M.gilvum_PYR-GCK GAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGK
Mvan_1264|M.vanbaalenii_PYR-1 GSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGK
MSMEG_0868|M.smegmatis_MC2_155 GAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGW
MAV_2913|M.avium_104 GAHEDEFSEPMYG-----------------------------FRPRIIGR
MLBr_01182|M.leprae_Br4923 GTGGVNTALRLQP------------------------------RAFVMPR
TH_3113|M.thermoresistible__bu ARRAASIVEPAGS---------------------AAAAAAARESAPIRRR
MAB_4284c|M.abscessus_ATCC_199 GSGSVGGSTAVGG------------------GAHTSAINDALGGSGSVGG
Mb1575c|M.bovis_AF2122/97 GDHLSGFRNSVPTITGTANISGFVN-AGTSISGFFNFG------------
Rv1548c|M.tuberculosis_H37Rv GDHLSGFRNSVPTITGTANISGFVN-AGTSISGFFNFG------------
MMAR_1297|M.marinum_M GSFSSGFRNTGPEGINPGFMSGFVNSSGTFISGFFNAGTFTPGL------
MUL_0902|M.ulcerans_Agy99 G-----FGN-----------AGIAN-SGNATFGIANSG------------
Mflv_5091|M.gilvum_PYR-GCK AGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG------
Mvan_1264|M.vanbaalenii_PYR-1 AGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG------
MSMEG_0868|M.smegmatis_MC2_155 VQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWK
MAV_2913|M.avium_104 PPAAG---------------------------------------------
MLBr_01182|M.leprae_Br4923 NPAAG---------------------------------------------
TH_3113|M.thermoresistible__bu RGQKDGLHGHRHEHQQPASMSAATAPSAAGIRVLGGAG------------
MAB_4284c|M.abscessus_ATCC_199 STAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMG------------
Mb1575c|M.bovis_AF2122/97 -------------------------------------------SLMSGFA
Rv1548c|M.tuberculosis_H37Rv -------------------------------------------SLMSGFA
MMAR_1297|M.marinum_M -----------------------------------------LETFNSGFG
MUL_0902|M.ulcerans_Agy99 -------------------------------------------ALSSGIS
Mflv_5091|M.gilvum_PYR-GCK -----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1 -----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG
MSMEG_0868|M.smegmatis_MC2_155 SGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSG
MAV_2913|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu -----------------------------------------RISRTRGSV
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------------SHGAA
Mb1575c|M.bovis_AF2122/97 NFDDEVSGYLNGDSRASGWIH-------
Rv1548c|M.tuberculosis_H37Rv NFDDEVSGYLNGDSRASGWIH-------
MMAR_1297|M.marinum_M NLGNQVSGLFNAQNVKSGPIH-------
MUL_0902|M.ulcerans_Agy99 NSGTNSSGGFNTGDDQSGFFN-------
Mflv_5091|M.gilvum_PYR-GCK --GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 --GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGNGGNGGADGTPGTAGTTGANNP
MAV_2913|M.avium_104 ----------------------------
MLBr_01182|M.leprae_Br4923 ----------------------------
TH_3113|M.thermoresistible__bu PHAEITPGDPTEPSSPTDRAHRPAEPN-
MAB_4284c|M.abscessus_ATCC_199 GTGFEAQGHAQGHASETAHTTLPGAEHH