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M. marinum M MMAR_1189 (-)

annotation: integral membrane protein
coordinates: 1438963 - 1439991
length: 342

LTTTTEPAKPGTLDRLRARYGWFDHAMRAAKRFNEQRGGFFAGGLTYYTIFALFPLLMVGFAVFGFVLAS
HPDLLKTIDGKIRESVSGALSQQLVGLMNSAIDARASVGLIGLATASWAGLTWMSHLRVALSEMWAHPVQ
RVGYVRTKLSDLTAMIGTFLVTMLTIALTALGHLRPMATVLSWFGIPELAIFNVVFRLISILISVLVAWL
MFTWMIARLPRQPGRLGTSMQAGLMAAIGFELFKQVASIYLRTVLRSPAGAAFGPVLGLMVFANVTAYLV
LFATAWAATKDPYSEHIEPPGPAIISPRIQVEEGLGVRQTVAALIAGAVGALTISRLFRRRR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_1189--100% (342)integral membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3368c-1e-11570.07% (284) integral membrane protein
M. gilvum PYR-GCKMflv_4870-1e-10054.07% (344) putative ribonuclease
M. tuberculosis H37RvRv3335c-1e-11570.07% (284) integral membrane protein
M. leprae Br4923MLBr_00687-1e-10061.46% (288) hypothetical protein MLBr_00687
M. abscessus ATCC 19977MAB_3682c-6e-9750.89% (336) hypothetical protein MAB_3682c
M. avium 104MAV_2739-1e-1126.80% (250) hypothetical protein MAV_2739
M. smegmatis MC2 155MSMEG_1658-1e-10757.91% (335) ribonuclease, putative
M. thermoresistible (build 8)TH_1975-1e-10557.57% (337) PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
M. ulcerans Agy99MUL_1442-0.099.42% (342) integral membrane protein
M. vanbaalenii PYR-1Mvan_1561-1e-10054.62% (346) putative ribonuclease

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1189|M.marinum_M               MTTTTEPAK----PGTLDRLRARYGWFDHAMRAAKRFNEQRGGFFAGGLT
MUL_1442|M.ulcerans_Agy99           MTTTTEPAK----PGTLDRLRARYGWFDHAMRAAKRFNEQRGGFFAGGLT
Mb3368c|M.bovis_AF2122/97           ---MGELAE----PGVLDRLRARFGWLDHVVRAFTRFNDRNGSLFAAGLT
Rv3335c|M.tuberculosis_H37Rv        ---MGELAE----PGVLDRLRARFGWLDHVVRAFTRFNDRNGSLFAAGLT
MLBr_00687|M.leprae_Br4923          ---MTEPAN----TGIIDRLRGRFRWLDHVVRAHQRFDERNGSFFAAGLT
Mflv_4870|M.gilvum_PYR-GCK          MTTQSATADPEDKPGFLDRQRARRPWFDHVMRAQERYKDSKGDFYAAGIT
Mvan_1561|M.vanbaalenii_PYR-1       MTAQPAPTDTEDKPGFLDRMRARMPWFDHVMRAQERYKDAKGDFYAAGIT
MSMEG_1658|M.smegmatis_MC2_155      ---MTEPADESAKPGLLDRLKARWPWFDHVMRAQERYNDSKGDFYAAGIT
TH_1975|M.thermoresistible__bu      ---VTEPSE----PGVLQRLRARYAWFDHVLRAQERYTEARGNHFAAGIT
MAB_3682c|M.abscessus_ATCC_199      --MVAEDDK----PGILDRYRARFPWFDHIMRMQERYGKVNGNFFAAGIT
MAV_2739|M.avium_104                ----------------------------MIVGVVYKYNDDQGGYLAALIT
                                                                  :    :: . .*.  *. :*

MMAR_1189|M.marinum_M               YYTIFALFPLLMVGFAVFGFVLASHPDLLKTIDGKIRESVSGALSQQLVG
MUL_1442|M.ulcerans_Agy99           YYTIFALFPLLMVGFAVFGFVLASHPDLLKTINGKIRESVSGALSQQLVG
Mb3368c|M.bovis_AF2122/97           YYTIFAIFPLLMVGFGVGGFALSRRPELLTTLEERIRTSVSGAVGQQLVD
Rv3335c|M.tuberculosis_H37Rv        YYTIFAIFPLLMVGFGVGGFALSRRPELLTTLEERIRTSVSGAVGQQLVD
MLBr_00687|M.leprae_Br4923          YYTIFALFPMLMVSFSVVGLVLFRRPELLTTIDDHIRSAVSSQLGQELVD
Mflv_4870|M.gilvum_PYR-GCK          YFTIFALFPLLMLGFSVAGFVLANQPELLQDVEERIRSTFSGDLGQQLVT
Mvan_1561|M.vanbaalenii_PYR-1       YFTIFALFPLLMLGFSVGGFVLASQPELLATVVERIRSAVSGELGRQLIE
MSMEG_1658|M.smegmatis_MC2_155      YFTIFALFPLLMVGFAVGGFVLASQPELMGQLEDKIRQAVSGDLGAQLVQ
TH_1975|M.thermoresistible__bu      YFTVFALFPLLMVGFSIGGFVLAGRPDLLRQIEDRIRTTVSGDASQQLIE
MAB_3682c|M.abscessus_ATCC_199      YFTVFALFPLMMVAFAVMGFVLSRRPDTIAELRGRISGAISGEVGNQLIN
MAV_2739|M.avium_104                YYALVSLFPLLLLLTTGLGVILAGRPDLQAQVLHSTLSEFP-VIGSQLHH
                                    *:::.::**::::     *. *  :*:    :       ..   . :*  

MMAR_1189|M.marinum_M               LMNSAIDARASVGLIGLATASWAGLTWMSHLRVALSEMW-AHPVQRVGYV
MUL_1442|M.ulcerans_Agy99           LMNSAIDARASVGLIGLATASWAGLTWMSHLRVALSEMW-AHPVQRVGYV
Mb3368c|M.bovis_AF2122/97           LMNSAIDARASVGVIGLATAAWVGLGWMWHLREALSQMW-AHPVAPAGYL
Rv3335c|M.tuberculosis_H37Rv        LMNSAIDARASVGVIGLATAAWVGLGWMWHLREALSQMW-AHPVAPAGYL
MLBr_00687|M.leprae_Br4923          LMNRAIDARASVGVVGLATAAWAGLCWMSHFRAALTKMWWEHHIDPSSLL
Mflv_4870|M.gilvum_PYR-GCK          LMDSAIESRGAVGLIGLATAAWAGLGWMANLREALSQMWGLFRGETPGFV
Mvan_1561|M.vanbaalenii_PYR-1       LMDSAIDSRGTVGVIGLATAAWAGLGWMANLREALSQMWGLYREESPGFV
MSMEG_1658|M.smegmatis_MC2_155      LMDSAIDSRTSVGVIGLATAAWAGLGWMANLREALSQMWGLFREEKPGFV
TH_1975|M.thermoresistible__bu      LMDSAIASRTSVGLIGLATATWAGLSWMANLREALSEMWEQ-RPEKGNFV
MAB_3682c|M.abscessus_ATCC_199      LMDTAIASRTSLGIAGLATAAWAGLGWMANVRAALSAMWEQ-PNDSENFV
MAV_2739|M.avium_104                PEG--LSGGAAGVIVGLAGALYGGLGVGQAVQNAMDSVWAVPKHKRPNPI
                                      .  : .  :  : *** * : **     .: *:  :*        . :

MMAR_1189|M.marinum_M               RTKLSDLTAMIGTFLVTMLTIALTALGHLRPMATVLSWFGIPELAIFNVV
MUL_1442|M.ulcerans_Agy99           RTKLSDLTAMIGTFLVTMLTIALTALGHLRPMATVLSWFGIPELAIFNVV
Mb3368c|M.bovis_AF2122/97           RTKLSDLAAMVGTFVVIVATIALTVLGHARPMAAVLRWLEIPQFSVFDEI
Rv3335c|M.tuberculosis_H37Rv        RTKLSDLAAMVGTFVVIVATIALTVLGHARPMAAVLRWLEIPQFSVFDEI
MLBr_00687|M.leprae_Br4923          RNKLSDLLAMVGTFVVFLTTLALTVLSHQAPMAAILRCIGITHFFVFGVI
Mflv_4870|M.gilvum_PYR-GCK          KTKLSDLVALLTTFVAIIVTLALSALGNSSLVENILTRIGFPDSPVLTVV
Mvan_1561|M.vanbaalenii_PYR-1       RTKLSDLLALLSAFAAIVVTLALTALGNTSVMAGVLARLGIEDAPGLSLM
MSMEG_1658|M.smegmatis_MC2_155      RTKLSDLLALLSAFVAIILTIGLTALGSSTAIENVLNRIGMPDSVGLSIL
TH_1975|M.thermoresistible__bu      RTKLSDLVALLSLFLALLVTFGLTALGDRAVMRGVLRRLEISEFPGLGIG
MAB_3682c|M.abscessus_ATCC_199      KGKLSDLLALGSTFVALALTIAVTAVGDEKTILRILGWMGLHDVAIPSVL
MAV_2739|M.avium_104                RSRVRSLLLLLVLGSAAIAATLLAAAGQATAGLGFLGKAGLA--------
                                    : :: .*  :     .   :  ::. .       .*    :         

MMAR_1189|M.marinum_M               FRLISILISVLVAWLMFTWMIARLPRQPGRLGTSMQAGLMAAIGFELFKQ
MUL_1442|M.ulcerans_Agy99           FRLISILISVLVAWLMFTWMIARLPRQPGRLGTSMQAGLMAAIGFELFKQ
Mb3368c|M.bovis_AF2122/97           FRGISVLVSVLVSWVLFTWMIGRLPREPVGLVTAARAGLMAAVGFELFKQ
Rv3335c|M.tuberculosis_H37Rv        FRGISVLVSVLVSWVLFTWMIGRLPREPVGLVTAARAGLMAAVGFELFKQ
MLBr_00687|M.leprae_Br4923          FQGASVLVSTLVSWLLFTWMIAWLPRKSVNLVASMRGGLIAAVGFELFKQ
Mflv_4870|M.gilvum_PYR-GCK          LRASSITVSVLVSWLLFTWIIARLPRERVGFRSSVRAGLIAALAFEVFKL
Mvan_1561|M.vanbaalenii_PYR-1       LRLASFAVSVLVSWSLFTWMIARLPRESVSFRSSVRAGMIAAVAFEIFKF
MSMEG_1658|M.smegmatis_MC2_155      LWVLSVLMSLFVSWLLFTWMIARLPRETVTFRSSLRAGLLAAVGFEIFKQ
TH_1975|M.thermoresistible__bu      LKVASIAVAMLVAWLLFTWVIARLPRTTVSLRSSVRAGLLAAIGFEIFKQ
MAB_3682c|M.abscessus_ATCC_199      LKVVTIAIATVLSWALFTWMIARLPRERLPFSSSVRAGLIAAIGFELFKQ
MAV_2739|M.avium_104                --LTSVAINALICLVLFRLTTAR----ALSYRQVWPGAVAAALVWQLLQW
                                        :. :  .:.  :*    .              ..: **: ::::: 

MMAR_1189|M.marinum_M               VASIYLRTVLR--SPAGAAFGPVLGLMVFANVTAYLVLFATAW-------
MUL_1442|M.ulcerans_Agy99           VASIYLRTVLR--SPAGAAFGPVLGLMVFANVTAYLVLFATAW-------
Mb3368c|M.bovis_AF2122/97           VGAIYLQIVLR--SPAGAVFGPVLGLMVFAFVTAWLILFATAW-------
Rv3335c|M.tuberculosis_H37Rv        VGAIYLQIVLR--SPAGAVFGPVLGLMVFAFVTAWLILFATAW-------
MLBr_00687|M.leprae_Br4923          VGSIYLQIVLR--SPAGSVFGPVLGVMVFSYFTAYLVLFAASW-------
Mflv_4870|M.gilvum_PYR-GCK          VASIYLRSVLT--GPAGATFGPVLGLMVFAYITSRLILFSTCW-------
Mvan_1561|M.vanbaalenii_PYR-1       FGSVYLRSVVT--GPAGATFGPVLGLMVFAYITSRLILFSAAW-------
MSMEG_1658|M.smegmatis_MC2_155      LASIYLKSVIT--GPAGATFGPVLGLMVFAYITARLVLFATAW-------
TH_1975|M.thermoresistible__bu      VGSVYLASVTT--GPAGATFGPVLGLMVFAYITSRLILFATAW-------
MAB_3682c|M.abscessus_ATCC_199      VASIYLSVIMH--GPAGSTFGPVLGIMVFAYITARLLLYATAW-------
MAV_2739|M.avium_104                FGAGYVAHVVKRASATNSVFALVLGALAFLFLASTVLVVCAEVNVVLVER
                                    ..: *:  :    ..:.:.*. *** :.*  .:: ::: .:         

MMAR_1189|M.marinum_M               --------AATKDPYS--EHIEPPGPAIISPRIQVEEGLGVRQTVA----
MUL_1442|M.ulcerans_Agy99           --------AATKDPYS--EHIEPPDPAIISPRIQVEEGLGVRQTVA----
Mb3368c|M.bovis_AF2122/97           --------AATASA------------------------------------
Rv3335c|M.tuberculosis_H37Rv        --------AATASA------------------------------------
MLBr_00687|M.leprae_Br4923          --------AATAELCM--KPVS------------------VQLPWS----
Mflv_4870|M.gilvum_PYR-GCK          --------AATTPENMRENEIPAPPPAVINNRVIARPGLQIWQGLT----
Mvan_1561|M.vanbaalenii_PYR-1       --------AATTPENMAEELIPAPAPAIINNRIINRPGLQAWQAVA----
MSMEG_1658|M.smegmatis_MC2_155      --------AATAEENLEAARVLPPEPVQITTRVQVREGAGVPAMLT----
TH_1975|M.thermoresistible__bu      --------AATSADSLAARPVEPPVGARITTRIQVREGVGVVGTLT----
MAB_3682c|M.abscessus_ATCC_199      --------AATSDENRPLAHVPPPEPVVITTRVETVERPSKLGVIA----
MAV_2739|M.avium_104                LYPRALLGAFSDDADLTSADRRTYTKKVKAERVKAFERVSVRLDDAKRSP
                                            * :                                       

MMAR_1189|M.marinum_M               ALIAGAVGALTISRLFRRRR
MUL_1442|M.ulcerans_Agy99           ALIAGAVGALTISRLFRRRR
Mb3368c|M.bovis_AF2122/97           --------------------
Rv3335c|M.tuberculosis_H37Rv        --------------------
MLBr_00687|M.leprae_Br4923          YLFPGRDESGS---------
Mflv_4870|M.gilvum_PYR-GCK          AAAVGAIGALSLSRRRR---
Mvan_1561|M.vanbaalenii_PYR-1       AATAGALGALSLTRWRRR--
MSMEG_1658|M.smegmatis_MC2_155      AAAAGAVGGFGLSRLRFRQ-
TH_1975|M.thermoresistible__bu      AAAIGALGALGLSRWLRH--
MAB_3682c|M.abscessus_ATCC_199      AFGAGVIGALGISWLGRGGD
MAV_2739|M.avium_104                AKTVGRLNIFGDVRRPRTP-