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M. leprae Br4923 MLBr_02228 (-)

annotation: hypothetical protein MLBr_02228
coordinates: 2645915 - 2646535
length: 206

MNSRFLPYATSPGRLTIQLLSDIAVVMWTTFWVLVGIAVYNTISTIADTGAQVESGAHGIADNLASASHG
MQLIPVLGNAVSKPLTLTSAAALDIADAGHSLNTTASWLAVLLALAVIALPILVAVVPWLVLRFWFFRHK
WTVTTLAATPAGKQLLALRALTLRSPSKLAAVSADPVGGWRREDPGTIRGLAALELQSSGITLRVH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02228--100% (206)hypothetical protein MLBr_02228

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0802c-3e-7567.16% (204) transmembrane protein
M. gilvum PYR-GCKMflv_1615-3e-5957.21% (201) putative transmembrane protein
M. tuberculosis H37RvRv0779c-3e-7567.16% (204) transmembrane protein
M. abscessus ATCC 19977MAB_0688c-2e-6058.08% (198) hypothetical protein MAB_0688c
M. marinum MMMAR_4910-5e-7567.16% (204) transmembrane protein
M. avium 104MAV_0724-6e-8072.55% (204) hypothetical protein MAV_0724
M. smegmatis MC2 155MSMEG_5842-3e-6760.78% (204) hypothetical protein MSMEG_5842
M. thermoresistible (build 8)TH_1815ctaD6e-1736.36% (121) PROBABLE CYTOCHROME C OXIDASE POLYPEPTIDE I CTAD (CYTOCHROME
M. ulcerans Agy99MUL_0496-8e-7566.67% (204) transmembrane protein
M. vanbaalenii PYR-1Mvan_5139-4e-6359.20% (201) putative transmembrane protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1615|M.gilvum_PYR-GCK          -------------MRSRWIPYATTPVRLLWQLVSDIVVIAWTAAWVWVGT
Mvan_5139|M.vanbaalenii_PYR-1       -------------MKSRWVPYATTPGRLMAQLFSDVVVVGWTAIWIFVGT
MLBr_02228|M.leprae_Br4923          -------------MNSRFLPYATSPGRLTIQLLSDIAVVMWTTFWVLVGI
MAV_0724|M.avium_104                -------------MTPRFLPYSTRPGRLAAQLFSDLAVVIWTGLWILVGL
Mb0802c|M.bovis_AF2122/97           -------------MRSRFLPYATTPGRLLAQLISDITVAVWTTLWMLVGL
Rv0779c|M.tuberculosis_H37Rv        -------------MRSRFLPYATTPGRLLAQLISDITVAVWTTLWMLVGL
MMAR_4910|M.marinum_M               -------------MKSRFLPYSTRPLRLAIQLFSDITVAVWTTLWVFVGI
MUL_0496|M.ulcerans_Agy99           -------------MKSRFLPYSTRPLRLAIQLFSDITVVVWTTLWVFVGI
MAB_0688c|M.abscessus_ATCC_199      ---------------MRFLPYSTRPGRLLAQLFSDIAVATWTTIWVFVGL
MSMEG_5842|M.smegmatis_MC2_155      -------------MRSRYLPYASRPGRLLAQLFSDVAVILWTAIWVLVGM
TH_1815|M.thermoresistible__bu      VGRIRADLCWDRAMRSRYVPYATTPARLLAQLLSDIVIALWIAVWVLVGM
                                                    *::**:: * **  **.**:.:  *   *: ** 

Mflv_1615|M.gilvum_PYR-GCK          AVHSAVSTIAEFGYQLEGGANGVAGN----LDNAGNSADGVPLIG-----
Mvan_5139|M.vanbaalenii_PYR-1       AVHSAVATIADFGYQVESGANGVAGN----LDSAGQSAEDVPLIG-----
MLBr_02228|M.leprae_Br4923          AVYNTISTIADTGAQVESGAHGIADN----LASASHGMQLIPVLG-----
MAV_0724|M.avium_104                AVYDAIATIADAGRQVESGAHGVAGN----LASAGHGAQHIPVVG-----
Mb0802c|M.bovis_AF2122/97           AVHDAISIIGEAGRQIEIGSHGIAGN----LAAAGQDAQRIPVVG-----
Rv0779c|M.tuberculosis_H37Rv        AVHDAISIIGEAGRQIEIGSHGIAGN----LAAAGQDAQRIPVVG-----
MMAR_4910|M.marinum_M               AVHRAISAIAEAGHQIETGSQGVAGN----LASAGHGAQHIPLVG-----
MUL_0496|M.ulcerans_Agy99           AVHRAISAIAEAGHQIDTGSQGVAGN----LASAGHGAQHIPLVG-----
MAB_0688c|M.abscessus_ATCC_199      AVHAAVATIAEVGRQVKNGADGISDN----LNSAGDSAHRIPLVG-----
MSMEG_5842|M.smegmatis_MC2_155      AVHSAVSTIAEVGRQVETGANGVSEN----LSSAGDSTDNVPLIG-----
TH_1815|M.thermoresistible__bu      AVHTAVSTIAEVGRNVHTGATGVSEXXXVALPFFGIVTEIFPVFSRKPVF
                                    **: ::: *.: * ::. *: *::      *   .   . .*:..     

Mflv_1615|M.gilvum_PYR-GCK          GALAGPLRGAGDAAREIAGAGQSLGVTAGWLAWLLALA------------
Mvan_5139|M.vanbaalenii_PYR-1       GAIGGPLTAAGDAAREIAGAGQTLGVTAGWLAWLLALA------------
MLBr_02228|M.leprae_Br4923          NAVSKPLTLTSAAALDIADAGHSLNTTASWLAVLLALA------------
MAV_0724|M.avium_104                DTVSKPLNSASQAALDMAGAGHDLDVAASWLAVLLAMA------------
Mb0802c|M.bovis_AF2122/97           DALSNPITAASQAALDIAGAGHNLDTTAGWLAVVLALA------------
Rv0779c|M.tuberculosis_H37Rv        DALSNPITAASQAALDIAGAGHNLDTTAGWLAVVLALA------------
MMAR_4910|M.marinum_M               DAVSKPIAAAADAALGIAEAGHNLDSTASWLAIVLALA------------
MUL_0496|M.ulcerans_Agy99           DAVSKPIAAAADAALGIAEAGHNLDSTASWLAIVLAFA------------
MAB_0688c|M.abscessus_ATCC_199      DKVGAPLRAASEAAADLAGAGHNLDTTASWLAVVLAIA------------
MSMEG_5842|M.smegmatis_MC2_155      DTLSKPLRAASDAALDIAGAGHNLDSTASWLAWVLALA------------
TH_1815|M.thermoresistible__bu      GYTALVYATVGIGALSMAVWAHHMFATGAVLLPFFAFTTYLIAVPTGIKF
                                    .  .     .. .*  :*  .: :  :.. *  .:*::            

Mflv_1615|M.gilvum_PYR-GCK          ------------------------------------VAAPPILALMMPWL
Mvan_5139|M.vanbaalenii_PYR-1       ------------------------------------VAAPPILALMMPWL
MLBr_02228|M.leprae_Br4923          ------------------------------------VIALPILVAVVPWL
MAV_0724|M.avium_104                ------------------------------------VVALPILVAVGPWL
Mb0802c|M.bovis_AF2122/97           ------------------------------------VAATPILAVAMPWL
Rv0779c|M.tuberculosis_H37Rv        ------------------------------------VAATPILAVAMPWL
MMAR_4910|M.marinum_M               ------------------------------------VAATPILAVAMPWL
MUL_0496|M.ulcerans_Agy99           ------------------------------------VAATPILAVAMPWL
MAB_0688c|M.abscessus_ATCC_199      ------------------------------------VAAPPILAFAGPWI
MSMEG_5842|M.smegmatis_MC2_155      ------------------------------------VAAAPILFVAMPWL
TH_1815|M.thermoresistible__bu      FNWIGTMWKGQLTFESPMLFSVGFILTFLIGGLSGVMLASPPLDFHVTDT
                                                                        : * * *    .  

Mflv_1615|M.gilvum_PYR-GCK          FLRVRFFRRKWTAVTLSSTWAG----------------------------
Mvan_5139|M.vanbaalenii_PYR-1       FLRVRFFRRKWTAVTLSSTWAG----------------------------
MLBr_02228|M.leprae_Br4923          VLRFWFFRHKWTVTTLAATPAG----------------------------
MAV_0724|M.avium_104                FLRLRFFRRKLTVTALAATPAG----------------------------
Mb0802c|M.bovis_AF2122/97           FLRLRFCRRKWTVTTLAATPAG----------------------------
Rv0779c|M.tuberculosis_H37Rv        FLRLRFCRRKWTVTTLAATPAG----------------------------
MMAR_4910|M.marinum_M               FLRLRFFRRKWTVTALAATAAG----------------------------
MUL_0496|M.ulcerans_Agy99           FLRLRFFRRKWTVTALAATAAG----------------------------
MAB_0688c|M.abscessus_ATCC_199      FLRIRFFRRKLIAVQLAATPAG----------------------------
MSMEG_5842|M.smegmatis_MC2_155      YLRVRFFRRKWTAITLASTAAG----------------------------
TH_1815|M.thermoresistible__bu      YFLVAHFHYVLFGTIVFATFAGVYFWFPKMTGRMLDERLAKLHFWLTFIG
                                     : . . :       : :* **                            

Mflv_1615|M.gilvum_PYR-GCK          --EQLLALRALANRPLPK----------------LAAINPDPVGA-----
Mvan_5139|M.vanbaalenii_PYR-1       --EQLLALRALANRPLPK----------------LAAISTDPVGA-----
MLBr_02228|M.leprae_Br4923          --KQLLALRALTLRSPSK----------------LAAVSADPVGG-----
MAV_0724|M.avium_104                --AQLLALRALANRPPRK----------------LTAVSADPVGG-----
Mb0802c|M.bovis_AF2122/97           --RQLLALRALANRPPGK----------------LAAVSTDPVGA-----
Rv0779c|M.tuberculosis_H37Rv        --RQLLALRALANRPPGK----------------LAAVSTDPVGA-----
MMAR_4910|M.marinum_M               --QQLLALRALTNRPAAK----------------LAAVSADPVGG-----
MUL_0496|M.ulcerans_Agy99           --QQLLALRALTNRPAAK----------------LAAVSADPVGG-----
MAB_0688c|M.abscessus_ATCC_199      --EQLLALRALANRPLKK----------------LAVITADPVSA-----
MSMEG_5842|M.smegmatis_MC2_155      --EQLLALRALANRPLSK----------------LTAVSDDPVGA-----
TH_1815|M.thermoresistible__bu      FHTTFLVQHWLGNEGMPRRYADYLPTDGFTELNIVSSVGAFILGASMLPF
                                        :*. : *  .   :                :: :    :..     

Mflv_1615|M.gilvum_PYR-GCK          -------WREQDPVAIRG------------------------------LA
Mvan_5139|M.vanbaalenii_PYR-1       -------WREQDPVAIRG------------------------------LA
MLBr_02228|M.leprae_Br4923          -------WRREDPGTIRG------------------------------LA
MAV_0724|M.avium_104                -------WRREDPATIRA------------------------------LA
Mb0802c|M.bovis_AF2122/97           -------WRREDPATMRA------------------------------LA
Rv0779c|M.tuberculosis_H37Rv        -------WRREDPATMRA------------------------------LA
MMAR_4910|M.marinum_M               -------WRREDPAIIRG------------------------------LA
MUL_0496|M.ulcerans_Agy99           -------WRREDPAIIRG------------------------------LA
MAB_0688c|M.abscessus_ATCC_199      -------WRAQDATAMRG------------------------------LA
MSMEG_5842|M.smegmatis_MC2_155      -------FQRQDQAAIRG------------------------------LA
TH_1815|M.thermoresistible__bu      IWNVFKSWRYGDPVTVDDPWGYGNSLEWATTCPPPRHNFYELPRIRSERP
                                           ::  *   :                                 .

Mflv_1615|M.gilvum_PYR-GCK          ALELRASGIRAANLKRAK----------------------
Mvan_5139|M.vanbaalenii_PYR-1       ALELRASGIRAANLKRAK----------------------
MLBr_02228|M.leprae_Br4923          ALELQSSGITLRVH--------------------------
MAV_0724|M.avium_104                ALELQSAGIAIRGM--------------------------
Mb0802c|M.bovis_AF2122/97           ALELRAAGIPLRGD--------------------------
Rv0779c|M.tuberculosis_H37Rv        ALELRAAGIPLRGD--------------------------
MMAR_4910|M.marinum_M               ALELRAAGVRLRYR--------------------------
MUL_0496|M.ulcerans_Agy99           ALELRAAGVRLRYR--------------------------
MAB_0688c|M.abscessus_ATCC_199      AVELKAAGIGVPKQWRT-----------------------
MSMEG_5842|M.smegmatis_MC2_155      ALELRSAGMRLRRIP-------------------------
TH_1815|M.thermoresistible__bu      AFELHYPHMIERMRAESHIGRSHGPADGDVTRMEDTNVRT
                                    *.**: . :