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M. leprae Br4923 MLBr_02095 (phoS2)

annotation: PstS component of phosphate uptake
coordinates: 2490990 - 2492099
length: 369

KLNQFGAAIGLLATGALLSGCGSDNNAAVGSARTGPSSGQVSCGGKPTLKASGSTAQANAMTRFVNAFER
SCPGQTLNYTANGSGAGVSEFNGNQTDFGGSDSPLSRKEYAAAEQRCGSQAWNLPVVFGPIAITYNVNGL
SSLNLDGPTTAKIFNGSIASWNDPAIQALNTGVALPAEPIHVVFRNDESGTTDNFQRYLDVASNGEWGKG
IGKTFKGGVGEGAKGNDGTSAAVKSTEGSITYNEWSFASARKLNTAKIATSADPEPIAISVDSVGKTISG
ATIIGEGNDLVLDTVSFYKPAQPGSYPIVLATYEIVCSKYPDAQVGRAVKAFLQSTIGGGQNGLGDNGYV
PIPDSFKSRLSTAANAIA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02095phoS2-100% (369)PstS component of phosphate uptake
M. leprae Br4923MLBr_02192phoS36e-8243.72% (366) phosphate-binding protein 3 precursor

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0951pstS31e-16977.57% (370) periplasmic phosphate-binding lipoprotein PSTS3 (PBP-3)
M. gilvum PYR-GCKMflv_1661-1e-14265.86% (372) phosphate ABC transporter, periplasmic phosphate-binding
M. tuberculosis H37RvRv0928pstS31e-16977.57% (370) periplasmic phosphate-binding lipoprotein PSTS3 (PBP-3)
M. abscessus ATCC 19977MAB_4852c-1e-15471.51% (372) phosphate ABC transporter periplasmic-binding protein
M. marinum MMMAR_4580phoS21e-17279.51% (371) periplasmic phosphate-binding lipoprotein PhoS2
M. avium 104MAV_1047pstS1e-17581.03% (369) phosphate ABC transporter, phosphate-binding protein PstS
M. smegmatis MC2 155MSMEG_5782pstS8e-9047.89% (380) phosphate ABC transporter, phosphate-binding protein PstS
M. thermoresistible (build 8)TH_0383pstS2e-9246.92% (373) phosphate ABC transporter, phosphate-binding protein PstS
M. ulcerans Agy99MUL_4441phoS21e-17279.25% (371) periplasmic phosphate-binding lipoprotein PhoS2
M. vanbaalenii PYR-1Mvan_5092-1e-14566.49% (373) phosphate ABC transporter, periplasmic phosphate-binding

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1661|M.gilvum_PYR-GCK          ---MKAKRTGAALS------MLAAGTLLLSACGSDNNTSSSGSGDGG-SE
Mvan_5092|M.vanbaalenii_PYR-1       ---MKANRTGAALS------LLAAGTLLLSACGSDNNTASSGSGEGGTAA
Mb0951|M.bovis_AF2122/97            ---MKLNRFGAAVG------VLAAGALVLSACGNDDN-VTGGGATTGQAS
Rv0928|M.tuberculosis_H37Rv         ---MKLNRFGAAVG------VLAAGALVLSACGNDDN-VTGGGATTGQAS
MMAR_4580|M.marinum_M               ---MKLNRVGAALS------VLASGALVLSACGSDNN-ASGGSSPAGQSS
MUL_4441|M.ulcerans_Agy99           ---MKLNRVGAALS------VLASGALVLSACGSDNN-ASGGSSPAGQSS
MAV_1047|M.avium_104                ---MKLNRFGAVLS------VLSAGALVLSGCGSDNN-GAGAG-AGGSSS
MLBr_02095|M.leprae_Br4923          ---MKLNQFGAAIG------LLATGAL-LSGCGSDNN-AAVGSARTGPSS
MAB_4852c|M.abscessus_ATCC_199      ---MKLNRFGAVLT------LVASGALVLSACGSDNN-ASGSSGSGSGDP
MSMEG_5782|M.smegmatis_MC2_155      ---MKLNSMGRKVGRPVGIAAAAIAALTLSACGSDNNAPATGTSGAAPSG
TH_0383|M.thermoresistible__bu      VGQVKFDGFGRAFG---SVSVAAVAALVLAGCGSDDNVP----TGAAPTG
                                       :* .  *  .         : .:* *:.**.*:*         .   

Mflv_1661|M.gilvum_PYR-GCK          P--AGDCGGKESLKASGSSAQANAMTRFINAYEKDCPGFTLNYTSSGSGA
Mvan_5092|M.vanbaalenii_PYR-1       P--AGDCGGKESLKASGSSAQANAMTRFINAYEKDCPGYTLNYTSSGSGA
Mb0951|M.bovis_AF2122/97            A--KVDCGGKKTLKASGSTAQANAMTRFVNVFEQACPGQTLNYTANGSGA
Rv0928|M.tuberculosis_H37Rv         A--KVDCGGKKTLKASGSTAQANAMTRFVNVFEQACPGQTLNYTANGSGA
MMAR_4580|M.marinum_M               ---NVSCGGKKTLKASGSTAQANAMTRFVKAFEEACPGQTLNYTGNGSGA
MUL_4441|M.ulcerans_Agy99           ---NVSCGGKKTLKASGSTAQANAMTRFVKAFEEACPGQTLNYTGNGSGA
MAV_1047|M.avium_104                S--KVSCGGKKALKASGSTAQANAMTRFVNAFEQACPGQTLNYTANGSGA
MLBr_02095|M.leprae_Br4923          G--QVSCGGKPTLKASGSTAQANAMTRFVNAFERSCPGQTLNYTANGSGA
MAB_4852c|M.abscessus_ATCC_199      A--GVSCGGKKSLKASGSTAQANAMTRFVNAYEQACSGYTLNYTSNGSGA
MSMEG_5782|M.smegmatis_MC2_155      SAASAECGGKNSLTAEGSTAQQNAIAEFNKAWGQVCGGKNLSYNPTGSGA
TH_0383|M.thermoresistible__bu      ---AADCGGKTNITAEGSTAQQNAVAMFNQVWGQLCPGKNMSYNPTGSGA
                                         .****  :.*.**:** **:: * :.: . * * .:.*. .****

Mflv_1661|M.gilvum_PYR-GCK          GVSEFLGGQTDFGGSDSPLSADKGEYEKAKARCGGSDAWNLPAVFGPIAI
Mvan_5092|M.vanbaalenii_PYR-1       GVSEFLGGQTDFGGSDSPLNAEKGEIEKAKERCGGSEAWNLPAVFGPIAI
Mb0951|M.bovis_AF2122/97            GISEFNGNQTDFGGSDVPLSKD--EAAAAQRRCG-SPAWNLPVVFGPIAV
Rv0928|M.tuberculosis_H37Rv         GISEFNGNQTDFGGSDVPLSKD--EAAAAQRRCG-SPAWNLPVVFGPIAV
MMAR_4580|M.marinum_M               GISEFNGNQTDFGGSDSPLSND--EAATAEQRCGGSPAWNLPVVFGPIAV
MUL_4441|M.ulcerans_Agy99           GISEFNGNQTDFGGSDSPLSND--EAATAEQRCGGSPAWNLPVVFGPIAV
MAV_1047|M.avium_104                GISEFNGKQTDFGGSDSPLAPS--EYAAAQQRCG-SPAWNLPVVFGPIAI
MLBr_02095|M.leprae_Br4923          GVSEFNGNQTDFGGSDSPLSRK--EYAAAEQRCG-SQAWNLPVVFGPIAI
MAB_4852c|M.abscessus_ATCC_199      GVSEFLGKQTDIGGSDSPLSKDKGEYDKAVQRCG-SPAWNLPVVFGPLAV
MSMEG_5782|M.smegmatis_MC2_155      GREQFIAKQVDIAGSDSALSGD--QVAAAAERCGGNPAWNLPLVFGPVAM
TH_0383|M.thermoresistible__bu      GREQFIAGQVDFAGSDSPLSES--QVPQAAQRCDGHPAWHLPLVFGPVAL
                                    * .:* . *.*:.*** .*  .  :   *  **.   **:** ****:*:

Mflv_1661|M.gilvum_PYR-GCK          TYNVAGVDGLVLDGPTLGKIFNGTVNTWNAPEIAALNEGATLPAEPITVI
Mvan_5092|M.vanbaalenii_PYR-1       TYNLEGVDGLVLDGPTLGKIFNGTVKTWDAPEIAALNQGVTLPAQPINVI
Mb0951|M.bovis_AF2122/97            TYNLNSVSSLNLDGPTLAKIFNGSITQWNNPAIQALNRDFTLPGERIHVV
Rv0928|M.tuberculosis_H37Rv         TYNLNSVSSLNLDGPTLAKIFNGSITQWNNPAIQALNRDFTLPGERIHVV
MMAR_4580|M.marinum_M               TYNISGVSSLNLDGTTLAKIFNGTITTWNDPAVAALNSGTSLPDTPIHVV
MUL_4441|M.ulcerans_Agy99           TYNISGVSSLNLDGTTLAKIFNGTITTWNDPAVAALNSGTSLPDTPIHVV
MAV_1047|M.avium_104                TYNVAGLNSLNLDGATAAKIFNGAITTWNDPGIQALNPGVALPAEPIHVV
MLBr_02095|M.leprae_Br4923          TYNVNGLSSLNLDGPTTAKIFNGSIASWNDPAIQALNTGVALPAEPIHVV
MAB_4852c|M.abscessus_ATCC_199      TYNLAGVDALVLDGPTAAKIFNGAITTWNDPALAALNPGASLPAEPIHVV
MSMEG_5782|M.smegmatis_MC2_155      AYNLEGVDKLVLNGDLLAKIFQGQITKWNDPAIAGLNEGTSLPDAAITPI
TH_0383|M.thermoresistible__bu      AYNLDGVDDLVLNADVLARIFQGQITNWNDPAIAALNEGVALPDAPITPI
                                    :**: .:. * *:.   .:**:* :  *: * : .** . :**   *  :

Mflv_1661|M.gilvum_PYR-GCK          FRSDESGTTDNFQKYLDAASDGAWGKGAGKSFAGGVGEGAKGNEGTSAAI
Mvan_5092|M.vanbaalenii_PYR-1       FRSDESGTTDNFQKYLDAASDGAWGKGAGKSFAGGVGEGAKGNEGTSAAI
Mb0951|M.bovis_AF2122/97            FRSDESGTTDNFQRYLQAASNGAWGKGAGKSFQGGVGEGARGNDGTSAAA
Rv0928|M.tuberculosis_H37Rv         FRSDESGTTDNFQRYLQAASNGAWGKGAGKSFQGGVGEGARGNDGTSAAA
MMAR_4580|M.marinum_M               FRSDESGTTDNFQRYLDAASDGAWGKGAGKSFKGGVGEGAKGNDGTSAAI
MUL_4441|M.ulcerans_Agy99           FRSDESGTTDNFQRYLDAASDGAWGKGAGKSFKGGVGEGAKGNDGTSAAI
MAV_1047|M.avium_104                FRNDESGTTDNFQKYLDAAADGAWGKGAGKTFKGGVGEGAKGNDGTSAAI
MLBr_02095|M.leprae_Br4923          FRNDESGTTDNFQRYLDVASNGEWGKGIGKTFKGGVGEGAKGNDGTSAAV
MAB_4852c|M.abscessus_ATCC_199      FRSDESGTTDNFQKYLNGASEGAWAKGAGKAFNGGVGEGAKGNEGTSAAI
MSMEG_5782|M.smegmatis_MC2_155      YRSDSSGTTDNFQKYLTAAAPQSWTKGDGSEFNGGAGEGAQKSSGVVQAV
TH_0383|M.thermoresistible__bu      YRSDSSGTTDNFQKYLAAAAPESWTRGDGSEFQGGAGEGAQKSAGVVQAV
                                    :*.*.********:**  *:   * :* *. * **.****: . *.  * 

Mflv_1661|M.gilvum_PYR-GCK          SSTPGSITYNEWSFAKAQGLSIAEIVTSAGPEPVELSVESAGKAIDGVKF
Mvan_5092|M.vanbaalenii_PYR-1       KNTPGSITYNEWSFAKAQNLSIAKIVTSAGPEPVELSTESAGKAIDGVKF
Mb0951|M.bovis_AF2122/97            KNTPGSITYNEWSFAQAQHLTMANIVTSAGGDPVAITIDSVGQTIAGATI
Rv0928|M.tuberculosis_H37Rv         KNTPGSITYNEWSFAQAQHLTMANIVTSAGGDPVAITIDSVGQTIAGATI
MMAR_4580|M.marinum_M               KNTEGSITYNEWSFAQAQHLNMAKVITSAGPEPVAISTESVGKTIAGAAI
MUL_4441|M.ulcerans_Agy99           KNTEGSITYNEWSFAQAQHLNMAKVITSAGPEPVAISTESVGKTIAGAAI
MAV_1047|M.avium_104                KATEGSITYNEWSFAQAQKLNMAKIITSAGPDAVAISADSVGKTIAGAKI
MLBr_02095|M.leprae_Br4923          KSTEGSITYNEWSFASARKLNTAKIATSADPEPIAISVDSVGKTISGATI
MAB_4852c|M.abscessus_ATCC_199      KNTPGAITYNEWSFAKAQNLSVAKIVTSAGPDPVEISVDTVGKTIAGATI
MSMEG_5782|M.smegmatis_MC2_155      QATPGSIGYVEKGFAEQAGLPFAQIDSGAG--AVELTDESAAKAIDAAKF
TH_0383|M.thermoresistible__bu      QATPGAIGYVEVGFAQQAGVPYAKLDSGAG--AVELTDESAGKAIDAARF
                                    . * *:* * * .**.   :  *:: :.*.  .: :: ::..::* .. :

Mflv_1661|M.gilvum_PYR-GCK          KGEGNDLVLDTASFYMPTEAGSYPIMLAAYEIVCSQYPDADVATAVKAFM
Mvan_5092|M.vanbaalenii_PYR-1       KGEGNDLVLDTTSFYKPSEPGAYPIVLAAYEIVCSQYPDAEVATAVKAFM
Mb0951|M.bovis_AF2122/97            SGVGNDLVLDTDSFYRPKRPGSYPIVLATYEIVCSKYPDSQVGTAVKAFL
Rv0928|M.tuberculosis_H37Rv         SGVGNDLVLDTDSFYRPKRPGSYPIVLATYEIVCSKYPDSQVGTAVKAFL
MMAR_4580|M.marinum_M               MGQGNDLVLDTVSFYKPTKPGSYPIVLATYEIVCSKYPDSQVGTAVRAFL
MUL_4441|M.ulcerans_Agy99           MGQGNDLVLDTVSFYKPTKPGSYPIVLGTYEIVCSKYPDSQVGTAVRAFL
MAV_1047|M.avium_104                SGQGNDLVLDTLSFYKPTQAGSYPIVLATYEIVCSKYPDPQVGTAVKAFL
MLBr_02095|M.leprae_Br4923          IGEGNDLVLDTVSFYKPAQPGSYPIVLATYEIVCSKYPDAQVGRAVKAFL
MAB_4852c|M.abscessus_ATCC_199      KGEGHDLVLDTTSFYKPTQAGAYPIVLATYEIVCSKYPDADTATAVKAFL
MSMEG_5782|M.smegmatis_MC2_155      AAEGNDLALDLNSLYGTKEAGAYPLVLATYEIVCSKGYDADTAAAVKSFL
TH_0383|M.thermoresistible__bu      AGDGQDLVLDLNSLYGTREPGAYPLVLATYEIVCSNGYDPDTATAVKSFL
                                     . *:**.**  *:* . ..*:**::*.:******:  *.:.. **::*:

Mflv_1661|M.gilvum_PYR-GCK          HSALGNGQTGLEENGYIPVPEAFKTRLTEAVDAINATS
Mvan_5092|M.vanbaalenii_PYR-1       HSALGNGQTGLEENGYIPIPEAFKTRLTEAVDAINATS
Mb0951|M.bovis_AF2122/97            QSTIGAGQSGLGDNGYIPIPDEFKSRLSTAVNAIA---
Rv0928|M.tuberculosis_H37Rv         QSTIGAGQSGLGDNGYIPIPDEFKSRLSTAVNAIA---
MMAR_4580|M.marinum_M               QSTIGAGQNGLADNGYIPIPDEFKSRLSTAVNAIA---
MUL_4441|M.ulcerans_Agy99           QSTIGAGQNGLADNGYIPIPDEFKSRLSTAVNAIA---
MAV_1047|M.avium_104                QSTVGAGQNGLADNGYIPIPDAFKSRLSAAINAIT---
MLBr_02095|M.leprae_Br4923          QSTIGGGQNGLGDNGYVPIPDSFKSRLSTAANAIA---
MAB_4852c|M.abscessus_ATCC_199      KSTIGPGQKGLSDNGYIPLPDAFGSKLSDAVGAIA---
MSMEG_5782|M.smegmatis_MC2_155      TVAANEGQANLSAAGYVPLPNAFKERLLTSIDAIS---
TH_0383|M.thermoresistible__bu      TAAADDGQSGLSAAGYVPLPERFKERLLGSIDAIGSNP
                                      : . ** .*   **:*:*: *  :*  : .**