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M. leprae Br4923 MLBr_01833 (secY)

annotation: preprotein translocase subunit SecY
coordinates: 2220681 - 2221997
length: 438

LSAFISSLRTVDLRRKILFTLGILVLYRVSAALPSPGVNYRHVQQCIQEATAGEAGEIYSLINLFSGGAL
LKLTVGVMPYITASIIVQLLTVVIPRFEELRKEGQAGQAKMTQYTRYLAIALAVLQATSIVALAANGGLL
QGCQEDIISDQSIFSLVVIVLVMTGGAALVMWMGELITERGIGNGMSLLIFVGIAARIPAEGKQILDSRG
GVIFAAVCLAALVIIVGVVFVEQGQRRIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYI
PHLITQLVRSGSGGVGKSWWDKFVGTYLSDPADPVYINIYFGLIIFFTYFYVSVTFNPDERADEMKKFGG
FIPGIRPGRPTADYLRYVLSRITLPGSIYLGAIAVLPNLFLQIGNGGEVQNLPFGGTAVLIMIGVGLDTV
KQIESQLMQRNYEGFLK*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_01833secY-100% (438)preprotein translocase subunit SecY

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0753secY0.091.84% (441) preprotein translocase subunit SecY
M. gilvum PYR-GCKMflv_5022secY0.080.67% (445) preprotein translocase subunit SecY
M. tuberculosis H37RvRv0732secY0.091.84% (441) preprotein translocase subunit SecY
M. abscessus ATCC 19977MAB_3784csecY0.079.95% (419) preprotein translocase subunit SecY
M. marinum MMMAR_1070secY0.091.38% (441) preprotein translocase, SecY
M. avium 104MAV_4434secY0.092.29% (441) preprotein translocase subunit SecY
M. smegmatis MC2 155MSMEG_1483secY0.085.71% (441) preprotein translocase subunit SecY
M. thermoresistible (build 8)TH_0325secY0.083.52% (443) PROBABLE PREPROTEIN TRANSLOCASE SECY
M. ulcerans Agy99MUL_0828secY0.091.38% (441) preprotein translocase subunit SecY
M. vanbaalenii PYR-1Mvan_1347secY0.081.57% (445) preprotein translocase subunit SecY

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5022|M.gilvum_PYR-GCK          ------------MLSAFISSLRTVDLRRKILFTLGIVILYRVGASIPSPG
Mvan_1347|M.vanbaalenii_PYR-1       ------------MLSAFISSLRTVDLRRKILFTLGIVILYRVGAQIPSPG
MSMEG_1483|M.smegmatis_MC2_155      ------------MLSAFISSLRTADLRRKILFTLGLVILYRVGASIPSPG
TH_0325|M.thermoresistible__bu      ------------VLSAFISSLRTADLRRKILFTLGIVLLYRVGASIPSPG
MLBr_01833|M.leprae_Br4923          ------------MLSAFISSLRTVDLRRKILFTLGILVLYRVSAALPSPG
MAV_4434|M.avium_104                MMQEIPAAQEEELLSAFISSLRTVDLRRKILFTLGIVVLYRVGAALPSPG
MMAR_1070|M.marinum_M               ------------MLSAFISSLRTVDLRRKILFTLGIVVLYRLGAALPSPG
MUL_0828|M.ulcerans_Agy99           ------------MLSAFISSLRTVDLRRKILFTLGIVVLYRLGAALPSPG
Mb0753|M.bovis_AF2122/97            ------------MLSAFISSLRTVDLRRKILFTLGIVILYRVGAALPSPG
Rv0732|M.tuberculosis_H37Rv         ------------MLSAFISSLRTVDLRRKILFTLGIVILYRVGAALPSPG
MAB_3784c|M.abscessus_ATCC_199      ------------------------------------MVLYRVGATLPSPG
                                                                        ::***:.* :****

Mflv_5022|M.gilvum_PYR-GCK          VNYPNVQQCIADVSGGESGQIYSLINLFSGGALLQLSVFAVGIMPYITAS
Mvan_1347|M.vanbaalenii_PYR-1       VNYPNVQQCIAEVSGGESGQIYSLINLFSGGALLQLSVFAVGIMPYITAS
MSMEG_1483|M.smegmatis_MC2_155      VNYPNVQQCIAQVSGGDSAQIYSLINLFSGGALLQLTVFAVGVMPYITAS
TH_0325|M.thermoresistible__bu      VNYPNVQRCIEQVSGGDSGQIYSLINLFSGGALLQLAVFAVGVMPYITAS
MLBr_01833|M.leprae_Br4923          VNYRHVQQCIQEATAGEAGEIYSLINLFSGGALLKLT---VGVMPYITAS
MAV_4434|M.avium_104                VNYPNVQQCIKEASGGAAGQIYSLINLFSGGALLKLTVFAVGVMPYITAS
MMAR_1070|M.marinum_M               VDFPNVQQCIKEASSGEAGQIYSLINLFSGGALLKLTVFAVGVMPYITAS
MUL_0828|M.ulcerans_Agy99           VDFPNVQQCIKEASSGEAGQIYSLINLFSGGALLKLTVFAVGVMPYITAS
Mb0753|M.bovis_AF2122/97            VNFPNVQQCIKEASAGEAGQIYSLINLFSGGALLKLTVFAVGVMPYITAS
Rv0732|M.tuberculosis_H37Rv         VNFPNVQQCIKEASAGEAGQIYSLINLFSGGALLKLTVFAVGVMPYITAS
MAB_3784c|M.abscessus_ATCC_199      VNYANVKYCVEQVSSGDSAQIYSLINLFSGGALLQLSVFAVGVMPYITAS
                                    *:: :*: *: :.:.* :.:**************:*:   **:*******

Mflv_5022|M.gilvum_PYR-GCK          IIVQLLGVVIPRFEQLRKEGQAGQTKLTQYTRYLAIALAILQATSIVALA
Mvan_1347|M.vanbaalenii_PYR-1       IIVQLLGVVIPRFEQLRKEGQAGQTKLTQYTRYLAIALAILQATSIVALA
MSMEG_1483|M.smegmatis_MC2_155      IIVQLLTVVIPRFEQLRKEGQAGQAKMTQYTRYLSIALAILQATSIVALA
TH_0325|M.thermoresistible__bu      IIVQLLTVVIPRFEQLRKEGQAGQAKMTQYTRYLAVALALLQATSIVALA
MLBr_01833|M.leprae_Br4923          IIVQLLTVVIPRFEELRKEGQAGQAKMTQYTRYLAIALAVLQATSIVALA
MAV_4434|M.avium_104                IIVQLLTVVIPRFEELRKEGQSGQAKMTQYTRYLAIALAILQATSIVALA
MMAR_1070|M.marinum_M               IIVQLLTVVIPRFEELRKEGQSGQAKMTQYTRYLAIALAVLQATSIVALA
MUL_0828|M.ulcerans_Agy99           IIVQLLTVVIPRFEELRKEGQSGQAKMTQYTRYLAIALAVLQATSIVALA
Mb0753|M.bovis_AF2122/97            IIVQLLTVVIPRFEELRKEGQAGQSKMTQYTRYLAIALAILQATSIVALA
Rv0732|M.tuberculosis_H37Rv         IIVQLLTVVIPRFEELRKEGQAGQSKMTQYTRYLAIALAILQATSIVALA
MAB_3784c|M.abscessus_ATCC_199      IIVQLLTVVIPRFEQLRKEGQSGQAKMTQYTRYLSVALALLQSTSIVALG
                                    ****** *******:******:**:*:*******::***:**:******.

Mflv_5022|M.gilvum_PYR-GCK          ANGGLLQGCS--LDIIQGQSEGLNVWTLAVIVIVMTAGAALVMWMGELVT
Mvan_1347|M.vanbaalenii_PYR-1       ANGGLLQGCA--LDIIEGQSEGLNIWTLTVIVIVMTAGAALVMWMGELVT
MSMEG_1483|M.smegmatis_MC2_155      ANGGLLQGCS--LDIIQDSS----IFGLIVIVLVMTAGAALVMWMGELVT
TH_0325|M.thermoresistible__bu      ANGGLLQGCT--LDIIDNSS----IFSLFVIVIVMTAGGALVMWMGELVT
MLBr_01833|M.leprae_Br4923          ANGGLLQGCQ--EDIISDQS----IFSLVVIVLVMTGGAALVMWMGELIT
MAV_4434|M.avium_104                ANGGLLQGCS--LDIIADQS----IFTLVVIVLVMTAGAALVMWMGELIT
MMAR_1070|M.marinum_M               ANGGLLQGCS--LEIIADQS----IFTLVVIVMVMTAGAALVMWMGELIT
MUL_0828|M.ulcerans_Agy99           ANGGLLQGCS--LEIIADQS----IFTLVVIVMVMTAGAALVMWMGELIT
Mb0753|M.bovis_AF2122/97            ANGGLLQGCS--LDIIADQS----IFTLVVIVLVMTGGAALVMWMGELIT
Rv0732|M.tuberculosis_H37Rv         ANGGLLQGCS--LDIIADQS----IFTLVVIVLVMTGGAALVMWMGELIT
MAB_3784c|M.abscessus_ATCC_199      ASGNLLQGCDRKDEIVADQS----IFALSVMVLVMTAGSTLVMWLGEMVT
                                    *.*.*****    :*: ..*    :: * *:*:***.*.:****:**::*

Mflv_5022|M.gilvum_PYR-GCK          ERGVGNGMSLIIFASIASAIPGEGKNILDSRGGMVFTLVCVAALIIVVGV
Mvan_1347|M.vanbaalenii_PYR-1       ERGVGNGMSLIIFASIAASIPGEGKNILDSRGGMVFTLVCVAAVVIVVGV
MSMEG_1483|M.smegmatis_MC2_155      ERGIGNGMSLLIFAGIAARIPAEGQTILESRGGVVFTAVVIAALVIIIGV
TH_0325|M.thermoresistible__bu      ERGIGNGMSLLIFAGIAAQIPAEGNMILESRGGLVFTAVCAAALVILIGV
MLBr_01833|M.leprae_Br4923          ERGIGNGMSLLIFVGIAARIPAEGKQILDSRGGVIFAAVCLAALVIIVGV
MAV_4434|M.avium_104                ERGIGNGMSLLIFVGIAARIPAEGKTILDSRGGMIFAAVLVAALIIIVGV
MMAR_1070|M.marinum_M               ERGIGNGMSLLIFVGIAARIPAEGNQIMESRGGVIFAAVCAATLIIIVGV
MUL_0828|M.ulcerans_Agy99           ERGIGNGMSLLIFVGIAARIPAEGNQIMESRGGVIFAAVCAATLIIIVGV
Mb0753|M.bovis_AF2122/97            ERGIGNGMSLLIFVGIAARIPAEGQSILESRGGVVFTAVCAAALIIIVGV
Rv0732|M.tuberculosis_H37Rv         ERGIGNGMSLLIFVGIAARIPAEGQSILESRGGVVFTAVCAAALIIIVGV
MAB_3784c|M.abscessus_ATCC_199      ERGIGNGMSLLIFAGIAARIPAEGKTILDSRGGVTFAAVCVAALLIVVGV
                                    ***:******:**..**: **.**: *::****: *: *  *:::*::**

Mflv_5022|M.gilvum_PYR-GCK          VFVEQGQRRIPVQYAKRMVGRKMYGGTSTYLPLKVNQAGVIPVIFASSLI
Mvan_1347|M.vanbaalenii_PYR-1       VFVEQGQRRIPVQYAKRMVGRKMYGGTSTYLPLKVNQAGVIPVIFASSLI
MSMEG_1483|M.smegmatis_MC2_155      VFVEQGQRRIPVQYAKRMVGRKMYGGTSTYLPLKVNQAGVIPVIFASSLI
TH_0325|M.thermoresistible__bu      VFVEQGQRRIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLI
MLBr_01833|M.leprae_Br4923          VFVEQGQRRIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLI
MAV_4434|M.avium_104                VFVEQGQRRIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLI
MMAR_1070|M.marinum_M               VFVEQGQRRIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLI
MUL_0828|M.ulcerans_Agy99           VFVEQGQRRIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLI
Mb0753|M.bovis_AF2122/97            VFVEQGQRRIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLI
Rv0732|M.tuberculosis_H37Rv         VFVEQGQRRIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLI
MAB_3784c|M.abscessus_ATCC_199      VFVEQGQRRIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLL
                                    *********************:***************************:

Mflv_5022|M.gilvum_PYR-GCK          YIPHLITQLITSA-SDSPSTGWWQSFVADYLTDPSSPVYIAIYFGLIIFF
Mvan_1347|M.vanbaalenii_PYR-1       YIPHLITQLITSA-SDTPSTGWWQTFVAEYLTDPSSPVYIAIYFGLIVFF
MSMEG_1483|M.smegmatis_MC2_155      YIPHLITQLIQSG-SSNPGTGWWDKFVADYLTNPADPVYIAVYFGLIVFF
TH_0325|M.thermoresistible__bu      YIPQLITQLIQSGRSDPTQTGWWDRFVAEYLTDPSSPVYIGIYFGLIIFF
MLBr_01833|M.leprae_Br4923          YIPHLITQLVRSG-SGGVGKSWWDKFVGTYLSDPADPVYINIYFGLIIFF
MAV_4434|M.avium_104                YIPHLITQLIRSG-SGGVGNSWWDKFVGSYLSDPSDPVYIGIYFGLIIFF
MMAR_1070|M.marinum_M               YIPHLITQLVRSG-SGGVGHSWWDKFVGTYLSDPSNLGYIAIYFGLIIFF
MUL_0828|M.ulcerans_Agy99           YIPHLITQLVRSG-SGGVGHSWWDKFVGTYLSDPSNLGYIAIYFGLIIFF
Mb0753|M.bovis_AF2122/97            YIPHLITQLIRSG-SGVVGNSWWDKFVGTYLSDPSNLVYIGIYFGLIIFF
Rv0732|M.tuberculosis_H37Rv         YIPHLITQLIRSG-SGVVGNSWWDKFVGTYLSDPSNLVYIGIYFGLIIFF
MAB_3784c|M.abscessus_ATCC_199      YIPGLITQLVRSG-GNKEKTGWWDRFVSTYLTDPSNYWYIAIYFTLIVFF
                                    *** *****: *. ..    .**: **. **::*:.  ** :** **:**

Mflv_5022|M.gilvum_PYR-GCK          TYFYVSITFNPEERADEMKKYGGFIPGIRPGKPTAQYLSFVLSRITLPGS
Mvan_1347|M.vanbaalenii_PYR-1       TYFYVSITFNPDERADEMKKYGGFIPGIRPGRPTADYLRFVLSRITLPGS
MSMEG_1483|M.smegmatis_MC2_155      TYFYVSITFNPDERADEMKKFGGFIPGIRPGKPTADYLRYVLSRITLPGS
TH_0325|M.thermoresistible__bu      TYFYVSITFNPDERADEMKKFGGFIPGIRPGRPTADYLRYVLSRITLPGS
MLBr_01833|M.leprae_Br4923          TYFYVSVTFNPDERADEMKKFGGFIPGIRPGRPTADYLRYVLSRITLPGS
MAV_4434|M.avium_104                TYFYVSITFNPDERADEMKKFGGFIPGIRPGKPTADYLRYVLSRITLPGS
MMAR_1070|M.marinum_M               TYFYVSITFNPDERADEMKKFGGFIPGIRPGRPTADYLRYVLSRITLPGS
MUL_0828|M.ulcerans_Agy99           TYFYVSITFNPDERADEMKKFGGFIPGIRPGRPTADYLRYVLSRITLPGS
Mb0753|M.bovis_AF2122/97            TYFYVSITFNPDERADEMKKFGGFIPGIRPGRPTADYLRYVLSRITLPGS
Rv0732|M.tuberculosis_H37Rv         TYFYVSITFNPDERADEMKKFGGFIPGIRPGRPTADYLRYVLSRITLPGS
MAB_3784c|M.abscessus_ATCC_199      TFFYVSITFNPDERADEMNKFGGFIPGIRPGRATADYLRYVLNRITWPGS
                                    *:****:****:******:*:**********:.**:** :**.*** ***

Mflv_5022|M.gilvum_PYR-GCK          IYLGVIAVLPNLFLEIGNTG-SVQNLPFGGTAVLIAVGVGLDTVKQIESQ
Mvan_1347|M.vanbaalenii_PYR-1       IYLGIIAVLPNLFLEIGNTG-SVQNLPFGGTAVLIAVGVALDTIKQIESQ
MSMEG_1483|M.smegmatis_MC2_155      IYLGVIAVLPNLFLEIGNTG-SVQNLPFGGTAVLIMIGVGLDTVKQIESQ
TH_0325|M.thermoresistible__bu      IYLGVIAVMPNVFLQMGSGGQTLQNLPFGGVAVLIMIGVGLDTVKQIESQ
MLBr_01833|M.leprae_Br4923          IYLGAIAVLPNLFLQIGNGG-EVQNLPFGGTAVLIMIGVGLDTVKQIESQ
MAV_4434|M.avium_104                IYLGAISVLPNLFLQIGNGG-AVQNLPFGGTAVLIMIGVGLDTVKQIESQ
MMAR_1070|M.marinum_M               IYLGVIAVLPNLFLQIGNSG-GVQNLPFGGTAVLIMIGVGLDTVKQIESQ
MUL_0828|M.ulcerans_Agy99           IYLGVIAVLPNLFLQIGNSG-GVQNLPFGGTAVLIMIGVGLDTVKQIESQ
Mb0753|M.bovis_AF2122/97            IYLGVIAVLPNLFLQIGAGG-TVQNLPFGGTAVLIMIGVGLDTVKQIESQ
Rv0732|M.tuberculosis_H37Rv         IYLGVIAVLPNLFLQIGAGG-TVQNLPFGGTAVLIMIGVGLDTVKQIESQ
MAB_3784c|M.abscessus_ATCC_199      IYLGVIAILPNLFLQIGSSG-GAQNLPFGGTAVLIMIGVGLDTVKQIESQ
                                    **** *:::**:**::*  *   *******.**** :**.***:******

Mflv_5022|M.gilvum_PYR-GCK          LMQRNYEGFLK
Mvan_1347|M.vanbaalenii_PYR-1       LMQRNYEGFLK
MSMEG_1483|M.smegmatis_MC2_155      LMQRNYEGFLK
TH_0325|M.thermoresistible__bu      LMQRNYEGFLK
MLBr_01833|M.leprae_Br4923          LMQRNYEGFLK
MAV_4434|M.avium_104                LMQRNYEGFLK
MMAR_1070|M.marinum_M               LMQRNYEGFLK
MUL_0828|M.ulcerans_Agy99           LMQRNYEGFLK
Mb0753|M.bovis_AF2122/97            LMQRNYEGFLK
Rv0732|M.tuberculosis_H37Rv         LMQRNYEGFLK
MAB_3784c|M.abscessus_ATCC_199      LMQRNYEGFLK
                                    ***********