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VSAAVAPTCKATMYVCGITPYDATHLGHAATYLAFDLIHRLWLDLGHEVHYVQNVTDVDDPLFERADRNG VDWRDLAEREVALFRDDMASLRILPPHDYVAATETIVEIVELVDKMLVSGAAYVIDDEYPDIYFRADATL QFGYESGYDRDTMLRLYEQSGGDPRRPGKNGELDALLWRAARPGEPSWSSPFGPGRPGWHVECAAIALSR IGIGLDIQGGGSDLIFPHHEFTAAHAECVRGERRFARHYVHAGMIGWDEHKMSKSRGNLVLVSTLRAQGA PPSAIRLGLLAGHYRADRFWSSQLLDDAIARLHRWRTAASMPAGPDVADVIARVRGYLADDLDTPKAIAA LDGWVTDALEYGGHDAAAPKLLATAIDALLGVDL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_01302 | cysS2 | - | 100% (384) | cysteinyl-tRNA synthetase |
| M. leprae Br4923 | MLBr_00323 | cysS | 2e-52 | 33.07% (381) | cysteinyl-tRNA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2154c | cysS | 0.0 | 85.12% (383) | cysteinyl-tRNA synthetase |
| M. gilvum PYR-GCK | Mflv_3049 | - | 1e-172 | 72.70% (381) | cysteinyl-tRNA synthetase |
| M. tuberculosis H37Rv | Rv2130c | cysS | 0.0 | 85.12% (383) | cysteinyl-tRNA synthetase |
| M. abscessus ATCC 19977 | MAB_2116 | - | 1e-168 | 74.13% (375) | cysteinyl-tRNA synthetase |
| M. marinum M | MMAR_3110 | mshC | 0.0 | 82.37% (380) | cysteinyl-tRNA synthetase, MshC |
| M. avium 104 | MAV_2361 | cysS | 0.0 | 80.99% (384) | cysteinyl-tRNA synthetase |
| M. smegmatis MC2 155 | MSMEG_4189 | cysS | 0.0 | 77.43% (381) | cysteinyl-tRNA synthetase |
| M. thermoresistible (build 8) | TH_3668 | - | 0.0 | 77.92% (385) | PUTATIVE cysteinyl-tRNA synthetase |
| M. ulcerans Agy99 | MUL_2360 | mshC | 0.0 | 82.11% (380) | cysteinyl-tRNA synthetase |
| M. vanbaalenii PYR-1 | Mvan_3478 | - | 0.0 | 77.95% (381) | cysteinyl-tRNA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3049|M.gilvum_PYR-GCK MPCDRKTSPDQHHALQIHRHHHRRKIRARVDAMQSWSAPSVPALPGRGPQ
Mvan_3478|M.vanbaalenii_PYR-1 ----MNQPSDLSHTS-----------MSRVEAMHSWSAPNVPALPGRGPQ
MSMEG_4189|M.smegmatis_MC2_155 --------------------------------MQSWSAPAIPVVPGRGPA
Mb2154c|M.bovis_AF2122/97 --------------------------------MQSWYCPPVPVLPGRGPQ
Rv2130c|M.tuberculosis_H37Rv --------------------------------MQSWYCPPVPVLPGRGPQ
MLBr_01302|M.leprae_Br4923 --------------------------------------------------
MMAR_3110|M.marinum_M --------------------------------MQSWSSAPVPIVPGRGPE
MUL_2360|M.ulcerans_Agy99 --------------------------------MQSWSSAPVPIVPGREPE
MAV_2361|M.avium_104 --------------------------------------------------
TH_3668|M.thermoresistible__bu --------------------------------MQSWPAPEVPTLPGQPPP
MAB_2116|M.abscessus_ATCC_1997 --------------------------------MQSWASAPVPELDGGGPQ
Mflv_3049|M.gilvum_PYR-GCK LRLFDSADRQIRPVSPGATATMYVCGITPYDATHLGHAATYLTFDLVNRV
Mvan_3478|M.vanbaalenii_PYR-1 LRLYDSADRQVRPVAPGATATMYVCGITPYDATHLGHAATYLTFDLVHRL
MSMEG_4189|M.smegmatis_MC2_155 LRLFDSADRQVRPVTPGPTATMYVCGITPYDATHLGHAATYLTFDLVHRL
Mb2154c|M.bovis_AF2122/97 LRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYVTFDLIHRL
Rv2130c|M.tuberculosis_H37Rv LRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYVTFDLIHRL
MLBr_01302|M.leprae_Br4923 ---------MSAAVAPTCKATMYVCGITPYDATHLGHAATYLAFDLIHRL
MMAR_3110|M.marinum_M LRLYDTADRQVRPVAPGNTATMYVCGITPYDATHLGHAATYLAFDLIHRL
MUL_2360|M.ulcerans_Agy99 LRLYDTADRQVRPVAPGNTATMYVCGITPYDATHLGHAATYLAFDLIHRL
MAV_2361|M.avium_104 ---------MAAGAGPGSAATMYVCGITPYDATHLGHAATYLAFDLIYRQ
TH_3668|M.thermoresistible__bu LRLYDSADRQIRPVTPGRTATMYVCGITPYDATHLGHAATYLAFDLIYRV
MAB_2116|M.abscessus_ATCC_1997 LRLYDTADRQVRPVTTGPTATMYVCGITPYDATHLGHAATYLTFDLIYRQ
. . **********************::***: *
Mflv_3049|M.gilvum_PYR-GCK WRDSGHDVHYVQNITDVDDPLFERAARDGIGWRELGDRETDLFREDMAAL
Mvan_3478|M.vanbaalenii_PYR-1 WRDSGHDVHYVQNITDVDDPLFERAQRDGIGWRELGDRETELFREDMAAL
MSMEG_4189|M.smegmatis_MC2_155 WLDAGHTVQYVQNVTDVDDPLFERAERDGIDWRTLGDRETQLFREDMAAL
Mb2154c|M.bovis_AF2122/97 WLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAAL
Rv2130c|M.tuberculosis_H37Rv WLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAAL
MLBr_01302|M.leprae_Br4923 WLDLGHEVHYVQNVTDVDDPLFERADRNGVDWRDLAEREVALFRDDMASL
MMAR_3110|M.marinum_M WLDLGHEVRYVQNVTDVDDPLFERADRDGVDWRDLAAQEVALFREDMAAL
MUL_2360|M.ulcerans_Agy99 WLDLGHEVRYVQNVTDVDDPLFERADRDGVDWRDLAAQEVALFREDMAAL
MAV_2361|M.avium_104 WLDLGHDVHYVQNVTDVDDPLLERAARDGIDWRALAEREVSLFREDMAAL
TH_3668|M.thermoresistible__bu WLDSGFDVHYVQNITDIDDPLLERAERDGVDWRDLAARETRLFTEDMAAL
MAB_2116|M.abscessus_ATCC_1997 WLDAGLDVHYVQNVTDIDDPLFERADRDGIDWRELGDRETELFRGDMTAL
* * * ::****:**:****:*** *:*:.** *. *. ** **::*
Mflv_3049|M.gilvum_PYR-GCK RVVPPRDYVAATEAIAEVIEVVEKLLASGAAYVVDD----AQYPDVYFHA
Mvan_3478|M.vanbaalenii_PYR-1 RVLPPRDYVAATEAIAEVVELVEKMLAAGAAYVVDD----PQYPDVYFRA
MSMEG_4189|M.smegmatis_MC2_155 RVLPPHDYVAATDAIAEVVEMVEKLLASGAAYIVED----AEYPDVYFRA
Mb2154c|M.bovis_AF2122/97 RVLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREM--GEYQDIYFRA
Rv2130c|M.tuberculosis_H37Rv RVLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREM--GEYQDIYFRA
MLBr_01302|M.leprae_Br4923 RILPPHDYVAATETIVEIVELVDKMLVSGAAYVID-----DEYPDIYFRA
MMAR_3110|M.marinum_M RVLSPHDYVGATEAVAEIIELVEKLLASGAAYVLD-----GEHPDVYYRS
MUL_2360|M.ulcerans_Agy99 RVLSPHDYVGATEAVAEIIELVEKLLASGAAYVLD-----GEHPDVYYRS
MAV_2361|M.avium_104 RILAPRDYVGATEAIADVVELVEKMLASGAAYVVD-----GEFPDIYYRA
TH_3668|M.thermoresistible__bu RVLPPRDYVAATEAIDEVIELIEKMLAAGAAYVVDCDVPGADYPDVYFRA
MAB_2116|M.abscessus_ATCC_1997 RVLPPREYVRATESIACIIELVEKMLASGAAYVVDD----PEYPDVYFRV
*::.*::** **::: ::*:::*:*..****::: :. *:*::
Mflv_3049|M.gilvum_PYR-GCK GATVQFGYESGYDRETMLALFAERGGDPDRPGKSDPLDALLWRAERPEEP
Mvan_3478|M.vanbaalenii_PYR-1 DATVQFGYESGYDRDTMLALFAERGGDPDRPGKSDPLDALLWLAERPGEP
MSMEG_4189|M.smegmatis_MC2_155 DATAQFGYESGYDRDTMLTLFAERGGDPDRPGKSDQLDALLWRAERPGEP
Mb2154c|M.bovis_AF2122/97 DATLQFGYESGYDRDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEP
Rv2130c|M.tuberculosis_H37Rv DATLQFGYESGYDRDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEP
MLBr_01302|M.leprae_Br4923 DATLQFGYESGYDRDTMLRLYEQSGGDPRRPGKNGELDALLWRAARPGEP
MMAR_3110|M.marinum_M DATLQFGYESGYDRDTMLGLFEQRGGDPGRPGKNDALDALLWRAARPGEP
MUL_2360|M.ulcerans_Agy99 DATLQFGYESGYDRDTMLGLFEQRGGDPGRPGKNDALDALLWRAARPGEP
MAV_2361|M.avium_104 DATLQFGYESGYDRETMLRLFAERGGDPQRPGKTDALDALLWRAARPGEP
TH_3668|M.thermoresistible__bu DATEQFGYESGYDRETMARLFAERGGDPDRPGKLDPLDALLWRAARPGEP
MAB_2116|M.abscessus_ATCC_1997 DATEQFGYESGYDIETMSRLFAERGGDPGRPGKANELDALLWRAARPGEP
.** ********* :** * : **** **** . ****** * ** **
Mflv_3049|M.gilvum_PYR-GCK SWPSPFGPGRPGWHVECAAIAMTRIGNVLDIQGGGSDLIFPHHEFSSAHA
Mvan_3478|M.vanbaalenii_PYR-1 SWPSPFGPGRPGWHVECAAIALSRIGTGLDIQGGGSDLIFPHHEFSAAHA
MSMEG_4189|M.smegmatis_MC2_155 SWPSPFGRGRPGWHVECSAIALTRIGTGLDIQGGGSDLIFPHHEYSAAHA
Mb2154c|M.bovis_AF2122/97 SWPSPFGPGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHA
Rv2130c|M.tuberculosis_H37Rv SWPSPFGPGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHA
MLBr_01302|M.leprae_Br4923 SWSSPFGPGRPGWHVECAAIALSRIGIGLDIQGGGSDLIFPHHEFTAAHA
MMAR_3110|M.marinum_M SWPSPFGPGRPGWHIECAAIALSRVGSGLDVQGGGSDLIFPHHEFTAAHA
MUL_2360|M.ulcerans_Agy99 SWPSPFGPGRPGWHIECAAIALSRVGSGLDVQGGGSDLIFPHHEFTAAHA
MAV_2361|M.avium_104 SWPSPFGNGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHA
TH_3668|M.thermoresistible__bu SWPSPFGPGRPGWHVECAAIALSRIGTGLDIQGGGSDLIFPHHEFSAAHA
MAB_2116|M.abscessus_ATCC_1997 SWEASFGPGRPGWHVECSAIVLRELGAGIDIQGGGSDLIFPHHEYSAAHA
** :.** ******:**:**.: .:* :*:*************:::***
Mflv_3049|M.gilvum_PYR-GCK ECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSQLRRDGVDPGAIR
Mvan_3478|M.vanbaalenii_PYR-1 ECVTGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSQLRRDGVDPAAIR
MSMEG_4189|M.smegmatis_MC2_155 ESVTGERRFARHYVHTGMIGWDGHKMSKSRGNLVLVSQLRAQGVDPSAIR
Mb2154c|M.bovis_AF2122/97 ECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSALRAQDVEPSAVR
Rv2130c|M.tuberculosis_H37Rv ECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSALRAQDVEPSAVR
MLBr_01302|M.leprae_Br4923 ECVRGERRFARHYVHAGMIGWDEHKMSKSRGNLVLVSTLRAQGAPPSAIR
MMAR_3110|M.marinum_M ECVTGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSGLRAEGVNPAAVR
MUL_2360|M.ulcerans_Agy99 ECVTGEQRFARHYVHAGMIGWDGHKMSKSRGNLVLVSGLRAEGVNPAAVR
MAV_2361|M.avium_104 ECVRGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSQLRGRGVEPAAIR
TH_3668|M.thermoresistible__bu ECVTGERRFARHYVHAGMIGWDGEKMSKSRGNLVLVSELRAAGHDPAAIR
MAB_2116|M.abscessus_ATCC_1997 EAVTAQRRFARHYVHAGMIGWDGHKMSKSRGNLVKVSGLTAQGVDPAAVR
*.* .::********:****** .********** ** * . *.*:*
Mflv_3049|M.gilvum_PYR-GCK LGLFAGHYRQDRYWSPAVLDEAQQRLHRWRSATALDGAPDATDVVARVRR
Mvan_3478|M.vanbaalenii_PYR-1 LGLFAGHYRDDRFWSPAVLDEALARLHRWRSATALAGAPDATDVVARVRR
MSMEG_4189|M.smegmatis_MC2_155 LGLFSGHYREDRFWSNEVLDEANARLARWRSATALPEAPDATDVIARVRQ
Mb2154c|M.bovis_AF2122/97 LGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDVVARVRR
Rv2130c|M.tuberculosis_H37Rv LGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDVVARVRR
MLBr_01302|M.leprae_Br4923 LGLLAGHYRADRFWSSQLLDDAIARLHRWRTAASMPAGPDVADVIARVRG
MMAR_3110|M.marinum_M LGLLAGHYRADRFWSQQVLDEAVGRLQRWRAATTLPAGPDAAAVVARVRQ
MUL_2360|M.ulcerans_Agy99 LGLLAGHYRADRFWSQQVLDEAVGRLQRWRAATTLPAGPDAAAVVARVRQ
MAV_2361|M.avium_104 LGLLAGHFRGDRYWSDQVLDEATARLRRWRTATALPAGPDATDVIARVRQ
TH_3668|M.thermoresistible__bu LGLLAGHYRADRFWSDQLLAEATERLHRWRSATALPAGPDATDVVARLRR
MAB_2116|M.abscessus_ATCC_1997 LGLLAGHYRADRSWSDAVLADAQGRLARWRHAVALSAAPSARDVVARVRR
***::**:* ** ** :* :* ** *** *.:: .* . *:**:*
Mflv_3049|M.gilvum_PYR-GCK YLADDLDTPKALAAIDGWAEDTLSYGGHDRTAGPTVSAAVDALLGVAL--
Mvan_3478|M.vanbaalenii_PYR-1 YLADDLDTPKALAALDGWATDALTYGGHDATAGTTVATAVDALLGIAL--
MSMEG_4189|M.smegmatis_MC2_155 YLADDLDTPKALAALDGWCTDALSYGGHDTESPRLVATTVDALLGVDL--
Mb2154c|M.bovis_AF2122/97 YLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL--
Rv2130c|M.tuberculosis_H37Rv YLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL--
MLBr_01302|M.leprae_Br4923 YLADDLDTPKAIAALDGWVTDALEYGGHDAAAPKLLATAIDALLGVDL--
MMAR_3110|M.marinum_M YLADDLNTPKAIAALDGWATDALDYGGHDEVAPRLVASTIDALLGVDL--
MUL_2360|M.ulcerans_Agy99 YLADDLNTPKAIAALDGWATDALDYGGHDEVAPRLVASTIDALLGVDL--
MAV_2361|M.avium_104 YLADDLNTPKALAALDGWTTDALDYGGHDTAAPRLVATAVDALLGVAL--
TH_3668|M.thermoresistible__bu YLADDLDTPKALAALDGWCTDALEYGGDDPDAPGAVAAAVDALLGVDLRG
MAB_2116|M.abscessus_ATCC_1997 YLADDLDTPNALAALDNWVTDALAYGGHDAAAGAQVRDAVDALLGVQL--
******:**:*:**:*.* *:: ***.* : : ::*****: *
Mflv_3049|M.gilvum_PYR-GCK ---
Mvan_3478|M.vanbaalenii_PYR-1 ---
MSMEG_4189|M.smegmatis_MC2_155 ---
Mb2154c|M.bovis_AF2122/97 ---
Rv2130c|M.tuberculosis_H37Rv ---
MLBr_01302|M.leprae_Br4923 ---
MMAR_3110|M.marinum_M ---
MUL_2360|M.ulcerans_Agy99 ---
MAV_2361|M.avium_104 ---
TH_3668|M.thermoresistible__bu PLE
MAB_2116|M.abscessus_ATCC_1997 ---