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M. leprae Br4923 MLBr_00715 (lpqC)

annotation: putative secreted hydrolase
coordinates: 854785 - 855699
length: 304

LNVARWLASVVLAVCLAGCVGRQVSASSRDQPGTFQFGGLNRTYVLHVPPGSPVGLVLNLHGGGGTGAGQ
QGLTDFDAVADLNNLLVAYPDGYDKSWADGRGASPADRRHVDDVGFLVELAAKLQSDFGVAPGHVFVTGM
SNGGFMSNKLACDRADMFAAIAPVAGTLGVDVACHPSQPVSVMDAHGTDDPLVPFNGGDVHGRGGVSHVV
SVTNMVEKWRTADGCQGDPSQQELPDVGDGTFVRRFDYTVCANSAEVVFYKINKGGHTWPGGKQYLPKVV
IGSTTCVFDASEVIAQFFLTHARS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00715lpqC-100% (304)putative secreted hydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3326clpqC1e-13072.00% (300) esterase lipoprotein LpqC
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv3298clpqC1e-13072.00% (300) esterase lipoprotein LpqC
M. abscessus ATCC 19977-----
M. marinum MMMAR_1236lpqC1e-12468.00% (300) esterase lipoprotein LpqC
M. avium 104MAV_4268-1e-13073.75% (301) LpqC protein
M. smegmatis MC2 155MSMEG_3463-8e-8551.33% (300) putative esterase
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_2651lpqC1e-12468.00% (300) esterase lipoprotein LpqC
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_00715|M.leprae_Br4923          MNVARWLASVVLAVCLAGCVGRQVSASS-RDQPG-TFQFGGLNRTYVLHV
MAV_4268|M.avium_104                MAYARWLWLAVLAVCVVGCGVRHVSAASARDISG-TFRSGGMDRTYMLHV
Mb3326c|M.bovis_AF2122/97           MPWARMLSLIVLMVCLAGCGGDQLLARHASSVA--TFQFGGLTRSYRLHV
Rv3298c|M.tuberculosis_H37Rv        MPWARMLSLIVLMVCLAGCGGDQLLARHASSVA--TFQFGGLTRSYRLHV
MMAR_1236|M.marinum_M               MLGVRWLSLLVLALCLVGCGEQQTSVPRARNEAG-MFAFGGLKRTYILHV
MUL_2651|M.ulcerans_Agy99           MLGVRWLSLLVLALCLVGCGEQQTSVPRARNEAG-MFAFGGLKRTYILHV
MSMEG_3463|M.smegmatis_MC2_155      -----MTSSLLGAAMMLGCAAPWAHAGPLGPIPAAQIDVGGMLRTYQLHL
                                              :    : **      .      .   :  **: *:* **:

MLBr_00715|M.leprae_Br4923          PPGS--PVGLVLNLHGGGGTGAGQQGLTDFDAVADLNNLLVAYPDGYDKS
MAV_4268|M.avium_104                PAGD--PVGLVLSLHGGGGTGIAQRGLTGFDAVADAHNLLVVYPDGYEKS
Mb3326c|M.bovis_AF2122/97           PPAE--PSGLVISLHGGGGTGAGQEALTDFDAVADAADLLVVYPDGYDKS
Rv3298c|M.tuberculosis_H37Rv        PPAE--PSGLVISLHGGGGTGAGQEALTDFDAVADAADLLVVYPDGYDKS
MMAR_1236|M.marinum_M               PPGP--PTGLVLNLHGGGSSGAGQQRLTDFDSAADANNLLVVYPNGYDKS
MUL_2651|M.ulcerans_Agy99           PPGP--PTGLVLNLHGGGSSGAGQQRLTDFDSAADANNLLVVYPNGYDKS
MSMEG_3463|M.smegmatis_MC2_155      PPGMDKPSGLVVNLHAAGLTGADQAALTHYDSVADAHGFAVVYPDGIDRS
                                    *..   * ***:.**..* :*  *  ** :*:.**  .: *.**:* ::*

MLBr_00715|M.leprae_Br4923          WADGRGASPADRRHVDDVGFLVELAAKLQSDFGVAPGHVFVTGMSNGGFM
MAV_4268|M.avium_104                WADGRGASPADRHHVDDVAFLVGLVTKLQNDYRVAPGHVFVTGMSNGGFM
Mb3326c|M.bovis_AF2122/97           WADGRGASPADRRHLDDVGFLVALAAKLVHDFDIAPGHVFATGMSNGGFM
Rv3298c|M.tuberculosis_H37Rv        WADGRGASPADRRHLDDVGFLVALAAKLVHDFDIAPGHVFATGMSNGGFM
MMAR_1236|M.marinum_M               WADGRGAAPADRRHLDDIGFLVALVGKVQKDFGVPAGHVFATGMSNGGFM
MUL_2651|M.ulcerans_Agy99           WADGRGAAPADRRHLDDNGFLVALVGKVQKDFGVPAGHVFATGMSNGGFM
MSMEG_3463|M.smegmatis_MC2_155      WADGRGASVPDREGVDDVGFITTLVDRLVTDFGIPRDRVYATGLSAGAFM
                                    *******: .**. :** .*:. *. ::  *: :. .:*:.**:* *.**

MLBr_00715|M.leprae_Br4923          SNKLACDRADMFAAIAPVAGTLGVDVACHPSQPVSVMDAHGTDDPLVPFN
MAV_4268|M.avium_104                SNRLACDRADVFAAVAPVAGTLGVGVACNPSRPVSVWAAHGTADPLVPFK
Mb3326c|M.bovis_AF2122/97           SNRLACDRADIFAAVAPVAGTLGVGVTCNPSRPVSVLEAHGTADPLVPFN
Rv3298c|M.tuberculosis_H37Rv        SNRLACDRADIFAAVAPVAGTLGVGVTCNPSRPVSVLEAHGTADPLVPFN
MMAR_1236|M.marinum_M               SNRLACDRADVFAAIAPIAGTLGVGVPCNPSRPVSVLAAHGTADRVVPFK
MUL_2651|M.ulcerans_Agy99           SNRLACDRADVFAAIAPIAGTLGVGVPCNPSRPVSVLAAHGTADRVVPFK
MSMEG_3463|M.smegmatis_MC2_155      ANRLACERADLFAAIAPVAGTLGSNVGCSPSQPVSVLAMYGTADPIVPFG
                                    :*:***:***:***:**:***** .* * **:****   :** * :*** 

MLBr_00715|M.leprae_Br4923          GGDVHGRGGVSHVVSVTNMVEKWRTADGCQGDPSQQELPDVGDGTFVRRF
MAV_4268|M.avium_104                GGAVRGRGGLSHAVSAEAMVDKWRKVDGCQGDPSMELLPDARDGTVVHRF
Mb3326c|M.bovis_AF2122/97           GGAVRGRGGLSHSISVASLVDRWRAVDGCQGDPSAAELPDVGDGTMVHLF
Rv3298c|M.tuberculosis_H37Rv        GGAVRGRGGLSHSISVASLVDRWRAVDGCQGDPSAAELPDVGDGTMVHLF
MMAR_1236|M.marinum_M               GGKVRGRGGLSRAISAASMIERWRAVDECQGKPAVAELPEAGDSTVVLRF
MUL_2651|M.ulcerans_Agy99           GGKVRGRGGLSRAISAASMIERWRAVDECQGKPAVAELPEAGDSTVVLRF
MSMEG_3463|M.smegmatis_MC2_155      GGVMNGRGGTSTVLSATELVDRWRGLDGCADDPAPETLPAVGDGTSTERL
                                    ** :.**** *  :*.  ::::**  * * ..*:   ** . *.* .  :

MLBr_00715|M.leprae_Br4923          DYTVCANSAEVVFYKINKGGHTWPGGKQYLPKVVIGSTTCVFDASEVIAQ
MAV_4268|M.avium_104                DSTSCAASTEVVFYRIDKGGHTWPGGKQYLPAAVIGPTTHTLDGSEAIAE
Mb3326c|M.bovis_AF2122/97           DSSSCAAGTEVISYQIDNGGHTWPGGRQYLPKAVIGATTRAFDGSQVIAQ
Rv3298c|M.tuberculosis_H37Rv        DSSSCAAGTEVISYQIDNGGHTWPGGRQYLPKAVIGATTRAFDGSQVIAQ
MMAR_1236|M.marinum_M               DSTACAPGTEVIFYQIGNGGHTWPGSRQYLPKPVIGATTRAFDGSEAIVQ
MUL_2651|M.ulcerans_Agy99           DSTACAPGTEVIFYQIGNGGHTWPGSRQYLPKPVIGATTRAFDGSEAIVQ
MSMEG_3463|M.smegmatis_MC2_155      TYAPCAAGTAVVFMRVDNGGHTWPGAPEVLPAQQVGLAIRGFDASVLSMD
                                      : ** .: *:  ::.:*******. : **   :* :   :*.*    :

MLBr_00715|M.leprae_Br4923          FFLTHARS
MAV_4268|M.avium_104                FFLAHARD
Mb3326c|M.bovis_AF2122/97           FFATHGRD
Rv3298c|M.tuberculosis_H37Rv        FFATHGRD
MMAR_1236|M.marinum_M               FFVTHARE
MUL_2651|M.ulcerans_Agy99           FFVTHARE
MSMEG_3463|M.smegmatis_MC2_155      FFEAHGR-
                                    ** :*.*