For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTIEVKDELSRLAVKSISARRAEVTSLLRFAGGLHIVGGRVVIEAEVDLENIARRLRKDIFDLYGYNAVV HVLSASGIRKSVRYVLRVANDGEALARQTGLLDMRGRPVRGLPAQVVGGSLIDAEAVWRGAFLAHGSLTE PGRSSALEVSCPGLEAALALVGAARKLGVNAKAREVRGADRVVVRDGEAIGVLLTRMGAQDTRLVWEERR MRREVRATANRLANFDDANLRRSARAAIAAAARAERALEILGDTVPDHLASAGKLRVEYRQASLEELGRL ADPPMTKDAVAGRIRRLLSMADRKAKVEGIPDTESAVTPDLLEDA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_00565 | - | - | 100% (325) | putative transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1458 | whiA | 1e-165 | 92.00% (325) | transcriptional regulatory protein WHIA |
| M. gilvum PYR-GCK | Mflv_3712 | - | 1e-161 | 90.15% (325) | hypothetical protein Mflv_3712 |
| M. tuberculosis H37Rv | Rv1423 | whiA | 1e-165 | 92.00% (325) | transcriptional regulatory protein WHIA |
| M. abscessus ATCC 19977 | MAB_2781c | - | 1e-160 | 89.23% (325) | hypothetical protein MAB_2781c |
| M. marinum M | MMAR_2230 | whiA | 1e-167 | 93.85% (325) | transcriptional regulatory protein WhiA |
| M. avium 104 | MAV_3357 | - | 1e-169 | 93.54% (325) | hypothetical protein MAV_3357 |
| M. smegmatis MC2 155 | MSMEG_3081 | - | 1e-161 | 91.28% (321) | hypothetical protein MSMEG_3081 |
| M. thermoresistible (build 8) | TH_1322 | - | 1e-155 | 86.15% (325) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN WHIA |
| M. ulcerans Agy99 | MUL_1817 | whiA | 1e-167 | 93.23% (325) | transcriptional regulatory protein WhiA |
| M. vanbaalenii PYR-1 | Mvan_2700 | - | 1e-161 | 90.15% (325) | hypothetical protein Mvan_2700 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3712|M.gilvum_PYR-GCK --MTAEVKDELSRLVVNSVSARRAEVASLLRFAGGLHIVSGRVVVEAEVD
Mvan_2700|M.vanbaalenii_PYR-1 --MTAEVKDELSRLVVNSVSARRAEVASLLRFAGGLHIVSGRVVVEAEVD
Mb1458|M.bovis_AF2122/97 --MTTDVKDELSRLVVKSVSARRAEVTSLLRFAGGLHIVGGRVVVEAELD
Rv1423|M.tuberculosis_H37Rv --MTTDVKDELSRLVVKSVSARRAEVTSLLRFAGGLHIVGGRVVVEAELD
MMAR_2230|M.marinum_M --MTTEVKDELSRLVVKSVSARRAEVTSLLRFAGGLHIVAGRVVVEAEVD
MUL_1817|M.ulcerans_Agy99 --MTTEVKDELSRLVVKSVSARRAEVTSLLRFAGGLHIVAGRVVVEAEVD
MLBr_00565|M.leprae_Br4923 --MTIEVKDELSRLAVKSISARRAEVTSLLRFAGGLHIVGGRVVIEAEVD
MAV_3357|M.avium_104 MAMTTEVKDELSRLVVKSVSARRAEVTSLLRFAGGLHIVGGRVVVEAEVD
MSMEG_3081|M.smegmatis_MC2_155 ------MKDELSRLVVNSVSARRAEVASLLRFAGGLHIVAGRVVVEAEVD
MAB_2781c|M.abscessus_ATCC_199 --MTAEVKDELSRLVVTQVSSRRAEVASLLRFAGGLHIVSGRVVVEAEVD
TH_1322|M.thermoresistible__bu VAMTAEVKDELSRLVVTSVTARRAEVASLLRFAGGLHIVNGRVVVEAEVD
:*******.*..:::*****:************ ****:***:*
Mflv_3712|M.gilvum_PYR-GCK LGIIARRLRKDIYDLYGYSAVVHVLSASGIRKSTRYVVRVAKDGEALARQ
Mvan_2700|M.vanbaalenii_PYR-1 LGIIARRLRKDIYDLYGYNAVVHVLSASGIRKSTRYVVRVAKDGEALARQ
Mb1458|M.bovis_AF2122/97 LGSIARRLRKEIFELYGYTAVVHVLSASGIRKSTRYVLRVANDGEALARQ
Rv1423|M.tuberculosis_H37Rv LGSIARRLRKEIFELYGYTAVVHVLSASGIRKSTRYVLRVANDGEALARQ
MMAR_2230|M.marinum_M LGSIARRLRKDIFDLYGYSAVVHVLSASGIRKNTRYVLRVANDGEALARQ
MUL_1817|M.ulcerans_Agy99 LGSIARRLRKDIFDLYGYSAVVHVLSASGIRKNTRYVLRVANDGEALARQ
MLBr_00565|M.leprae_Br4923 LENIARRLRKDIFDLYGYNAVVHVLSASGIRKSVRYVLRVANDGEALARQ
MAV_3357|M.avium_104 LGNVARRLRKDIFELYGYNAVVHVLSASGIRKSTRYVLRVANDGEALARQ
MSMEG_3081|M.smegmatis_MC2_155 LGIIARRLRKDIYDLYGYNAVVHVLSASGIRKNTRYVVRVANDGEALARQ
MAB_2781c|M.abscessus_ATCC_199 QGSIARRLRKDIFDLYGYNAVVHVLSAGGIRKTTRYVVRVAKDGEALARQ
TH_1322|M.thermoresistible__bu LGITARRLRQAIYDLYGYTAAVQVLSASGVRKNTRYVVRVVKDGEALARQ
*****: *::****.*.*:****.*:**..***:**.:********
Mflv_3712|M.gilvum_PYR-GCK TGLLDLRGRPVRGLPAQVVGGSVADAEAAWRGAFLAHGSLTEPGRSSALE
Mvan_2700|M.vanbaalenii_PYR-1 TGLLDLRGRPVRGLPAQVVGGSVGDAEAAWRGAFLAHGSLTEPGRSSALE
Mb1458|M.bovis_AF2122/97 TGLLDMRGRPVRGLPAQVVGGSIDDAEAAWRGAFLAHGSLTEPGRSSALE
Rv1423|M.tuberculosis_H37Rv TGLLDMRGRPVRGLPAQVVGGSIDDAEAAWRGAFLAHGSLTEPGRSSALE
MMAR_2230|M.marinum_M TGLLDMRGRPVRGLPAQVVGGSIGDAEAAWRGAFLAHGSLTEPGRSSALE
MUL_1817|M.ulcerans_Agy99 TGLFDMRGRPVRGLPAQVVGGSIGDAEAAWRGAFLAHGSLTEPGRSSALE
MLBr_00565|M.leprae_Br4923 TGLLDMRGRPVRGLPAQVVGGSLIDAEAVWRGAFLAHGSLTEPGRSSALE
MAV_3357|M.avium_104 TGLLDNRGRPVRGLPAQVVGGSIADAEAAWRGAFLAHGSLTEPGRSSALE
MSMEG_3081|M.smegmatis_MC2_155 TGLLDMRGRPVRGLPAQVVGGSVGDAEAAWRGAFLAHGSLTEPGRSSALE
MAB_2781c|M.abscessus_ATCC_199 TGLLDLRGRPVRGLPAQVVGGSVADAEAAWRGAFLAHGSLTEPGRSSALE
TH_1322|M.thermoresistible__bu TGLLDMRGRPVRGLPAHVVGGSIADAEAAWRGAFLAHGSLTEPGRSSALE
***:* **********:*****: ****.*********************
Mflv_3712|M.gilvum_PYR-GCK VSCPGPEAALALVGAARRLGVSAKAREVRGSDRVVVRDGEAIGALLTRMG
Mvan_2700|M.vanbaalenii_PYR-1 VSCPGPEAALALVGAARRLGVSAKAREVRGSDRVVVRDGEAIGALLTRMG
Mb1458|M.bovis_AF2122/97 VSCPGPEAALALVGAARRLGVGAKAREVRGADRVVVRDGEAIGALLTRMG
Rv1423|M.tuberculosis_H37Rv VSCPGPEAALALVGAARRLGVGAKAREVRGADRVVVRDGEAIGALLTRMG
MMAR_2230|M.marinum_M VSCPGPEAALALVGAARRLGVGAKAREVRGADRVVVRDGEAIGALLTRMG
MUL_1817|M.ulcerans_Agy99 VSCPGPEAALALVGAARRLGVGAKAREVRGADRVVVRDGEAIGALLTRMG
MLBr_00565|M.leprae_Br4923 VSCPGLEAALALVGAARKLGVNAKAREVRGADRVVVRDGEAIGVLLTRMG
MAV_3357|M.avium_104 VSCPGPEAALALVGAARRLGVSAKAREVRGADRVVVRDGEAIGALLTRMG
MSMEG_3081|M.smegmatis_MC2_155 VSCPGPEAALALVGAARRLGVSAKAREVRGSDRVVVRDGEAIGALLTRMG
MAB_2781c|M.abscessus_ATCC_199 VSCPGPEAALALVGAARRLGVSAKAREVRGSDRVVVRDGEAIGALLTRMG
TH_1322|M.thermoresistible__bu VSCPGPEAALALVGAARRLGVSAKAREVRGSDRVVVRDGDAIGALLTRMG
***** ***********:***.********:********:***.******
Mflv_3712|M.gilvum_PYR-GCK AQDTRLTWEERRMRREVRATANRLANFDDANLRRSARAAVAAAARVERAL
Mvan_2700|M.vanbaalenii_PYR-1 AQDTRLTWEERRMRREVRATANRLANFDDANLRRSARAAVAAAARVERAL
Mb1458|M.bovis_AF2122/97 AQDTRLVWEERRLRREVRATANRLANFDDANLRRSARAAVAAAARVERAL
Rv1423|M.tuberculosis_H37Rv AQDTRLVWEERRLRREVRATANRLANFDDANLRRSARAAVAAAARVERAL
MMAR_2230|M.marinum_M AQDTRLVWEERRMRREVRATANRLANFDDANLRRSARAAVAAAARVERAL
MUL_1817|M.ulcerans_Agy99 AQDTRLVWEERRMRREVRATANRLANFDDANLRRSARAAVAAAARVERAL
MLBr_00565|M.leprae_Br4923 AQDTRLVWEERRMRREVRATANRLANFDDANLRRSARAAIAAAARAERAL
MAV_3357|M.avium_104 AQDTRLIWEERRMRREVRATANRLANFDDANLRRSARAAVAAAARVERAL
MSMEG_3081|M.smegmatis_MC2_155 AQDTRLTWEERRMRREVRATANRLANFDDANLRRSARAAVAAAARVERAL
MAB_2781c|M.abscessus_ATCC_199 AQDTRLTWEERRMRREVRATANRLANFDDANLRRSARAAVAAAARVERAL
TH_1322|M.thermoresistible__bu AQDTRLTWEERRMRREVRATANRLANFDDANLRRSARAAVAAAARVERAL
****** *****:**************************:*****.****
Mflv_3712|M.gilvum_PYR-GCK EILGDTVPDHLAAAGTLRVAHRQASLEELGRLADPPMTKDAVAGRIRRLL
Mvan_2700|M.vanbaalenii_PYR-1 QILGDTVPDHLAAAGNLRVAHRQASLEELGRLADPPMTKDAVAGRIRRLL
Mb1458|M.bovis_AF2122/97 EILGDTVPEHLASAGKLRVEHRQASLEELGRLADPPMTKDAVAGRIRRLL
Rv1423|M.tuberculosis_H37Rv EILGDTVPEHLASAGKLRVEHRQASLEELGRLADPPMTKDAVAGRIRRLL
MMAR_2230|M.marinum_M EILGDTVPDHLASAGKLRVEHRQASLEELGRLADPPMTKDAVAGRIRRLL
MUL_1817|M.ulcerans_Agy99 EILGDTVPDHLASAGKLRVEHRQVSLEELGRLADPPMTKDAVAGRIRRLL
MLBr_00565|M.leprae_Br4923 EILGDTVPDHLASAGKLRVEYRQASLEELGRLADPPMTKDAVAGRIRRLL
MAV_3357|M.avium_104 EILGDTVPDHLASAGKLRVEHRQASLEELGRLADPPMTKDAVAGRIRRLL
MSMEG_3081|M.smegmatis_MC2_155 EILGDSVPDHLAAAGKLRVEHRQASLEELGRLADPPMTKDAVAGRIRRLL
MAB_2781c|M.abscessus_ATCC_199 EILGDTVPDHLAAAGKLRVEHRQASLEELGRLADPVMTKDAVAGRIRRLL
TH_1322|M.thermoresistible__bu EILGDSVPEHLAAAGRLRIEHRQASLEELGRLADPPMTKDAVAGRIRRLL
:****:**:***:** **: :**.*********** **************
Mflv_3712|M.gilvum_PYR-GCK SMADRKAKQDGIPDTESAVTPDLLEDA
Mvan_2700|M.vanbaalenii_PYR-1 SMADRKAKQDGIPDTESAVTPDLLEDA
Mb1458|M.bovis_AF2122/97 SMADRKAKVDGIPDTESVVTPDLLEDA
Rv1423|M.tuberculosis_H37Rv SMADRKAKVDGIPDTESVVTPDLLEDA
MMAR_2230|M.marinum_M SMADRKAKVEGIPDTESAVTPDLLEDA
MUL_1817|M.ulcerans_Agy99 SMADRKAKVEGIPDTESAVTPDLLEDA
MLBr_00565|M.leprae_Br4923 SMADRKAKVEGIPDTESAVTPDLLEDA
MAV_3357|M.avium_104 SMADRKAKIEGIPDTESAVTPDLLEDA
MSMEG_3081|M.smegmatis_MC2_155 SMADRKAKQEGIPDTESAVTPDLLDDA
MAB_2781c|M.abscessus_ATCC_199 SMADRKAKTEGIPDTESAVTPELLEEA
TH_1322|M.thermoresistible__bu SMADRKAKQEGIPDTESAVTPELLEEA
******** :*******.***:**::*