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M. leprae Br4923 MLBr_00232 (-)

annotation: pantothenate kinase
coordinates: 302850 - 303674
length: 274

VLLAIDVRNTHTVVGLLSGSKEHAKVVQQWRIRTESEVTADELALIIDGLIGDDSERLAGAAALSTVPSV
LHEVRIMLDQYWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAFHKFGQAAIVVDFGSSICVDV
VSAKGEFLGGAIAPGVQVSSDAAAARSAALRRVELARPRSVVGKNTVECMQAGVVFGFAGLVDGLVGRMR
QDVEEFSGDLGNRVAVVATGHTAPLLLPELHTVDHYDRHLTLHGLRLVFERNREAQRGRLKTAR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00232--100% (274)pantothenate kinase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3630c-1e-13790.88% (274) pantothenate kinase
M. gilvum PYR-GCKMflv_1426-1e-12583.94% (274) pantothenate kinase
M. tuberculosis H37RvRv3600c-1e-13790.88% (274) pantothenate kinase
M. abscessus ATCC 19977MAB_0543-1e-12381.75% (274) pantothenate kinase
M. marinum MMMAR_5103-1e-13689.42% (274) hypothetical protein MMAR_5103
M. avium 104MAV_0553-1e-13990.15% (274) pantothenate kinase
M. smegmatis MC2 155MSMEG_6096-1e-13286.50% (274) pantothenate kinase
M. thermoresistible (build 8)TH_2349-1e-11075.55% (274) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_4182-1e-13689.05% (274) pantothenate kinase
M. vanbaalenii PYR-1Mvan_5362-1e-13085.40% (274) pantothenate kinase

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_00232|M.leprae_Br4923          MLLAIDVRNTHTVVGLLSGSKEHAKVVQQWRIRTESEVTADELALIIDGL
MAV_0553|M.avium_104                MLLAIDVRNTHTVVGLISGSKEHAKVVQQWRIRTESEITADELALTIDGL
Mb3630c|M.bovis_AF2122/97           MLLAIDVRNTHTVVGLLSGMKEHAKVVQQWRIRTESEVTADELALTIDGL
Rv3600c|M.tuberculosis_H37Rv        MLLAIDVRNTHTVVGLLSGMKEHAKVVQQWRIRTESEVTADELALTIDGL
MMAR_5103|M.marinum_M               MLLAIDVRNTHTVVGLLSGAKQHAKVVQQWRIRTESEVTADELALTIDGL
MUL_4182|M.ulcerans_Agy99           MLLAIDVRNTHTVVGLLSGAKQHAKVVQQWRIRTESEVTADELALTIDGL
MSMEG_6096|M.smegmatis_MC2_155      MLLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADELALTIDGL
Mvan_5362|M.vanbaalenii_PYR-1       MLLAIDVRNTHTVVGLISGSGDHAKVEQHWRIRTEPEVTADELALTIDGL
Mflv_1426|M.gilvum_PYR-GCK          MLLAIDVRNTHTVVGLISGSGSHGKVEHHWRIRTESEVTADELALTIDGL
TH_2349|M.thermoresistible__bu      VLLAIDVRNTHTVVGLISGSGSHAKVS-----------------------
MAB_0543|M.abscessus_ATCC_1997      MLLAIDVRNTHTVLGLVSGTGEHAKVVQHWRIRTEAEITADELALTIDGL
                                    :************:**:**  .*.**                        

MLBr_00232|M.leprae_Br4923          IGDDSERLAGAAALSTVPSVLHEVRIMLDQYWPSVPHVLIEPGVRTGIPL
MAV_0553|M.avium_104                IGDDSERLTGAAALSTVPSVLHEVRLMLDQYWPSVPHVLIEPGVRTGIPL
Mb3630c|M.bovis_AF2122/97           IGEDSERLTGTAALSTVPSVLHEVRIMLDQYWPSVPHVLIEPGVRTGIPL
Rv3600c|M.tuberculosis_H37Rv        IGEDSERLTGTAALSTVPSVLHEVRIMLDQYWPSVPHVLIEPGVRTGIPL
MMAR_5103|M.marinum_M               IGEDSERLTGATGLSTVPSVLHEVRIMLEQYWPSVPHVLIEPGVRTGIPL
MUL_4182|M.ulcerans_Agy99           IGEDSERLTGATGLSTVPSVLHEVRIMLEQYWPSVPHVLIEPGVRTGIPL
MSMEG_6096|M.smegmatis_MC2_155      IGDDAERLTGASGLSTVPSVLHEVRVMLEQYWPNVPHVLIEPGVRTGIPL
Mvan_5362|M.vanbaalenii_PYR-1       IGDDAERLTGAAGLSTVPSVLHEVRVMLDQYWPSVPHVLIEPGVRTGIPL
Mflv_1426|M.gilvum_PYR-GCK          IGDDAELLTGAAGLSTVPSVLHEVRVMLEQYWPSVPHVLIEPGVRTGIPL
TH_2349|M.thermoresistible__bu      ------------ALSTVPSVLHEVRIMLEQYWPSVPHVLIEPGVRTGIPL
MAB_0543|M.abscessus_ATCC_1997      IGDDSETLTGVAALSTVPSVLHEMRGMFDQYWSSVPQVLIEPGVRTGLPL
                                                .**********:* *::***..**:**********:**

MLBr_00232|M.leprae_Br4923          LVDNPKEVGADRIVNCLAAFHKFGQAAIVVDFGSSICVDVVSAKGEFLGG
MAV_0553|M.avium_104                LVDNPKEVGADRIVNCLAAFHRFQSPAIVIDFGSSICVDVVSAKGEFLGG
Mb3630c|M.bovis_AF2122/97           LVDNPKEVGADRIVNCLAAYDRFRKAAIVVDFGSSICVDVVSAKGEFLGG
Rv3600c|M.tuberculosis_H37Rv        LVDNPKEVGADRIVNCLAAYDRFRKAAIVVDFGSSICVDVVSAKGEFLGG
MMAR_5103|M.marinum_M               LVDNPKEVGADRIVNCLAAYQQFAKAAIVVDFGSSICVDVVSAKGEFLGG
MUL_4182|M.ulcerans_Agy99           LVDNPKEVGADRIVNCLAAYQQFAKAAIVVDFGSSICVDVVSAKGEFLGG
MSMEG_6096|M.smegmatis_MC2_155      LVDNPKEVGADRIVNCLAAYHKYGTAAIVVDFGSSICVDVVSAKGEFLGG
Mvan_5362|M.vanbaalenii_PYR-1       LVDNPKEVGADRIVNCLAAYHKFGTASIVVDFGSSICVDVVSAKGEFLGG
Mflv_1426|M.gilvum_PYR-GCK          LVDNPKEVGADRIVNCLAAYQKYGSAAIVVDFGSSICVDVVSAKGEFLGG
TH_2349|M.thermoresistible__bu      LVDNPKEVGADRIVNCLAAYHKFGTAAIVVDFGSSICVDVVSAKGEFLGG
MAB_0543|M.abscessus_ATCC_1997      LVDNPKEVGADRIVNCLAAHHRFGSACIVVDFGSSICVDVVSAKGEFLGG
                                    *******************..::  ..**:********************

MLBr_00232|M.leprae_Br4923          AIAPGVQVSSDAAAARSAALRRVELARPRSVVGKNTVECMQAGVVFGFAG
MAV_0553|M.avium_104                AIAPGLQVSSDAAAARSAALRRVELARPRSVIGKNTVECMQAGAVFGFAG
Mb3630c|M.bovis_AF2122/97           AIAPGVQVSSDAAAARSAALRRVELARPRSVVGKNTVECMQAGAVFGFAG
Rv3600c|M.tuberculosis_H37Rv        AIAPGVQVSSDAAAARSAALRRVELARPRSVVGKNTVECMQAGAVFGFAG
MMAR_5103|M.marinum_M               AIAPGVQVSSDAAAARSAALRRVELARPRSVVGKNTVECMQAGAVFGFAG
MUL_4182|M.ulcerans_Agy99           AIAPGVQVSSDAAAARSAALRRVELARPRSVVGKNTVECMQAGAVFGFAG
MSMEG_6096|M.smegmatis_MC2_155      AIAPGVQVSSDAAAARSAALRRVELTRPRSVIGKNTVECMQAGAVFGFAG
Mvan_5362|M.vanbaalenii_PYR-1       AIAPGVQVSSDAAAERSAALRRVELTRPRSVVGKNTVECMQAGAVFGFAG
Mflv_1426|M.gilvum_PYR-GCK          AIAPGVQVSSDAAAARSAALRRVELTRPRSVVGKNTVECMQAGAVFGFAA
TH_2349|M.thermoresistible__bu      AIAPGVQVSSDAAAARSAALRRVELTRPRSVIGKNTVECMQAGAVFGFAG
MAB_0543|M.abscessus_ATCC_1997      AIAPGVQVSSDAAAARSAALRRVELTRPRSVVGKNTVECMQSGAVFGFAG
                                    *****:******** **********:*****:*********:*.*****.

MLBr_00232|M.leprae_Br4923          LVDGLVGRMRQDVEEFSGDLGNRVAVVATGHTAPLLLPELHTVDHYDRHL
MAV_0553|M.avium_104                LVDGLVGRIREDVPGFGGDD---VAIVATGHTAPLLLPELDTVSHYDQHL
Mb3630c|M.bovis_AF2122/97           LVDGLVGRIREDVSGFSVDHD--VAIVATGHTAPLLLPELHTVDHYDQHL
Rv3600c|M.tuberculosis_H37Rv        LVDGLVGRIREDVSGFSVDHD--VAIVATGHTAPLLLPELHTVDHYDQHL
MMAR_5103|M.marinum_M               LVDGLVARIREDVKGFSADDD--VAVVATGHTAPLLLPELHSVEHFDEHL
MUL_4182|M.ulcerans_Agy99           LVDGLVARIREDVKGFSADDD--VAVVATGHTAPLLLPELHSVEHFDEHL
MSMEG_6096|M.smegmatis_MC2_155      LVDGLVNRIRDDVDGFSGAD---VAVVATGHTAPLVLPDLRTVEHYDRHL
Mvan_5362|M.vanbaalenii_PYR-1       LVDGLVSRVRDDVDGFGGGD---VNVVATGHGAPLVLADLRTVEHYDRHL
Mflv_1426|M.gilvum_PYR-GCK          LVDGLVNRIREDVDGFGGDD---VTVVATGHSAPLVLEDLSTVQHYDRHL
TH_2349|M.thermoresistible__bu      LVDGLVNRVRRDVDGFTG-D---VAVVATGHIAPILLPDLETVEHYDRYL
MAB_0543|M.abscessus_ATCC_1997      LVDGLVERVRRDIDGFGAAG---VTVVATGHTAPLILPETHTVDRYEEHL
                                    ****** *:* *:  *       * :***** **::* :  :*.:::.:*

MLBr_00232|M.leprae_Br4923          TLHGLRLVFERNREAQRGRLKTAR
MAV_0553|M.avium_104                TLHGLRLVFERNRDAQRGRLKTAR
Mb3630c|M.bovis_AF2122/97           TLQGLRLVFERNLEVQRGRLKTAR
Rv3600c|M.tuberculosis_H37Rv        TLQGLRLVFERNLEVQRGRLKTAR
MMAR_5103|M.marinum_M               TLHGLRLVFERNREAQRGRLKPAR
MUL_4182|M.ulcerans_Agy99           TLNGLRLVFERNREAQRGRLKPAR
MSMEG_6096|M.smegmatis_MC2_155      TLDGLRLVFERNRANQRGKLKPAR
Mvan_5362|M.vanbaalenii_PYR-1       TLDGLRLVFERNRDSQRGKLKQAR
Mflv_1426|M.gilvum_PYR-GCK          TLDGLRLVFERNRDNQR-KLKQAR
TH_2349|M.thermoresistible__bu      TLDGLRLVFERNRDSSRGRLRQAR
MAB_0543|M.abscessus_ATCC_1997      TLDGLRLVYERNRADQRGKARATR
                                    **.*****:***   .* : : :*